Learn about the latest medical breakthroughs by participating in webinars on topics surrounding disease, prevention and treatment in accordance with the latest research in health and medicine. Updates encompass a biological, psychological and sociological understanding of health.
Learning Objectives 1. Identify 3 obstacles that inhibit the immune cell response to cancer. 2. List 3 aspects of T cells antitumor function that can be improved with costimulatory signals....
Changes in transcriptional regulation are thought to be one of the key drivers of carcinogenesis. Although next-generation sequencer revolutionized transcriptome analysis, there are limitati...
In 2012, the Choosing Wisely initiative was commenced by the ABIM with numerous societies putting forward lists of overused tests or procedures. The Choosing Wisely movement has spread to nu...
Major depression (MDD) is a common psychiatric condition and a leading cause of disability worldwide. While psychotherapy and pharmacotherapy are effective treatments for the majority of peo...
Recent developments in reporters for calcium, voltage, and neurotransmitters, together with interest in understanding neuronal circuit function, have driven the development of methods for fa...
The opioid crisis erupted from a tragic convergence of factors from the private and public sectors. Changing sensibilities on opioid use and abuse, perspectives on addiction and recovery, be...
The enzyme-linked immunosorbent assay (ELISA) is one of the most common techniques performed in both research and clinical laboratories to detect the molecules of interest in fluid samples....
Background: Despite the immunogenicity and safety profile of dendritic cell (DC) vaccines, the importance of vaccine-induced antigen-specific T cell responses is unclear across clinical tria...
Within this talk the advantages of using intensified Design of experiments (iDoE) in combination with hybrid modeling will be demonstrated. In detailed upstream and downstream showcases the...
The global pandemic has increased focus and scrutiny on molecular diagnostic assay development, resulting in a need for assays that provide quick results while delivering expected performanc...
Multi-mode chromatography has come to prominence in recent years due to the general utility of multi-mode ligands for product capture and polishing. In particular, their application in flow-t...
Image-based approaches to single-cell transcriptomics are emerging as powerful complements to single-cell RNA sequencing, in part, because these techniques preserve the native spatial contex...
Organoids are emerging tools to study homeostatic function and disease of human organs. This technology has now for the first time been extended to reptiles by establishing cultures of the s...
Malaria is a life-threatening disease that is caused by unicellular eukaryotic parasites of the genus Plasmodium, with P. falciparum being responsible for the most severe form of human malar...
The transport properties of biomolecules in cells can reveal a great deal about the functional interactions regulating cells at the molecular level. Various biophysical methods have been dev...
Image manipulation scandals and tightening journal guidelines have put traditional Western blots under a spotlight: every manual step—from gel casting to image export—adds variab...
While many technologies focus on either exploring the spatial context of a handful of targets, or expression patterns of hundreds or thousands of targets in bulk samples or dissociated singl...
Dr. Christopher E. Mason Professor of Genomics, Physiology, and Biophysics at Weill Cornell Medicine and the Director of the WorldQuant Initiative for Quantitative Prediction Digital PCR for...
Most currently used conventional influenza vaccines are based on 1940s technology. Advances in immunogen design and vaccine delivery emerging over the last decade open novel opportunities fo...
Cas9 based therapeutics have the potential to revolutionize the treatment of genetic diseases. However, safe and effective methods for delivering Cas9 protein, gRNA and donor DNA need to be...
Interest in cell and gene therapy-based disease prevention and treatment has increased rapidly over the last few decades, however there are still many hurdles to overcome and further progres...
The COVID-19 pandemic has taken a dramatic toll worldwide. Its impact possibly has been the most palpable amongst uniquely vulnerable groups of patients, such as patients with a cancer diagn...
Accurate prediction of CYP2D6 activity from genotype data is of utmost importance as CYP2D6 pharmacogenetic (PGx) testing is increasingly used to guide drug therapy. However, given the compl...
Recent evidence indicates that the immunoglobulin (IG) gene loci reside within the most complex and variable regions of the human genome, characterized by elevated levels of single nucleotide...