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    Animal disease model development

    Animal disease models are non-human animals used to research strategies to detect, prevent, or treat human disease. A variety of animals, including mice, rats, rabbits, and non-human primates are used for animal disease modeling. New animal disease models are developed regularly as knowledge of disease expand and technological improvements enhance current models.

    Webinars

    • FEB 05, 2015 | 12:00 PM
      C.E. CREDITS
      The importance of pre-operative assessment and post-operative care in surgical procedures
      The importance of pre-operative assessment and post-operative...
      The pre-operative assessment and post-operative is critical for successful surgical procedures which will in turn lead to high quality outcomes in research studies. The care of the animals go...
      Speaker: Pilar Ariza Guzman, DVM, MS
      Presented at: Laboratory Animal Sciences Virtual Event Series 2015
      6
      FEB 04, 2015 | 1:30 PM
      C.E. CREDITS
      The Surgeons Toolbox: outcomes are only as good as the contents of the box
      The Surgeons Toolbox: outcomes are only as good as the contents...
      The field of surgical research has been growing rapidly with the development of new surgical and disease models. An extremely important and often overlooked aspect of creating these models is...
      Speaker: Szczepan Baran, VMD, MS
      Presented at: Laboratory Animal Sciences Virtual Event Series 2015
      4
      FEB 04, 2015 | 9:00 AM
      C.E. CREDITS
      Keynote: Applying Principles of Biosafety in Laboratory Animal Facilities
      Keynote: Applying Principles of Biosafety in Laboratory Animal...
      Some commonly accepted principles of biosafety include the strict adherence to standard laboratory practices and techniques, the use of safety equipment such as primary barriers and personal...
      Speaker: James R Swearengen, DVM
      Presented at: Laboratory Animal Sciences Virtual Event Series 2015
      14
      OCT 30, 2014 | 3:00 PM
      Clinical Shotgun Proteomics in Cancer Biomarker and Drug Target Research/Discovery
      Clinical Shotgun Proteomics in Cancer Biomarker and Drug Target...
      Mass spectrometry (MS)-based profiling of clinical specimens has been increasingly used in cancer research to characterize changes in protein expression between tumor and healthy tissue or be...
      Speaker: Josip Blonder, MD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      30
      SEP 24, 2014 | 2:00 PM
      Development and Applications of CRISPR-Cas9 for Genome Editing
      Development and Applications of CRISPR-Cas9 for Genome Editing
      The RNA-guided nuclease Cas9 from the microbial CRISPR adaptive immune system has emerged as an exciting tool for precise genome editing in eukaryotic cells. This presentation will discuss th...
      Speaker: Feng Zhang, Ph.D.
      Presented at: Advances in Drug Discovery and Development
      39
      AUG 21, 2014 | 8:45 AM
      From Genetics to Genetic Medicine: Gene Therapy for vision restoration as a case study
      From Genetics to Genetic Medicine: Gene Therapy for vision restoration...
      Gene therapy for two forms of inherited retinal degeneration have met promising safety and efficacy endpoints in early stage clinical trials. These approaches made use of a replication defect...
      Speaker: Luk H Vandenberghe, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2014
      0
      MAY 29, 2014 | 10:30 AM
      Why are we unable to lose weight and keep it off? All about the connection between the gut and the brain
      Why are we unable to lose weight and keep it off? All about the...
      Obesity is a disease. It was once not considered to be a disease and to be a matter of will power and gluttony. It was also the case that we once thought that fat tissue had no metabolic func...
      Speaker: Caroline M Apovian, MD, FACP, FACN
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2014
      53
      MAR 20, 2014 | 1:00 PM
      The role of high throughput sequencing in the research and diagnosis of neurodegenerative disorders
      The role of high throughput sequencing in the research and diagnosis...
      Using high throughput next-generation sequencing to simultaneously search large number of genes for pathogenic mutations has numerous advantages. It decreases the pressure to narrow the dif...
      Speaker: Peter L Nagy, MD, PhD
      Presented at: Neuroscience Virtual Event Series 2014
      0
      MAR 20, 2014 | 6:00 AM
      Connectomics - Defining Neural Circuits to Understand Brain Function
      Connectomics - Defining Neural Circuits to Understand Brain Function
      Connectomics is a new field of research that aims to map the synapses of the nervous system in order to construct a wiring diagram of all the neural circuits. It is necessary to use the elect...
      Speaker: Scott W. Emmons, PhD
      Presented at: Neuroscience Virtual Event Series 2014
      54
      MAR 19, 2014 | 8:00 AM
      BRAIN Initiative Panel Discussion - science overview
      BRAIN Initiative Panel Discussion - science overview
      The Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative is part of a new Presidential focus aimed at revolutionizing our understanding of the human brain. By...
      Speaker: Emery N. Brown, MD, PhD, William Newsome, PhD, Justin Sanchez, PhD, Terrence J Sejnowski, PhD
      Presented at: Neuroscience Virtual Event Series 2014
      59
      FEB 06, 2014 | 12:00 PM
      C.E. CREDITS
      Molecular Diagnostic Tests To Advance Health Monitoring of Laboratory Zebrafish
      Molecular Diagnostic Tests To Advance Health Monitoring of Laboratory...
      The zebrafish, Danio rerio, is an ideal model organism to address a broad array of biomedical questions, and is now widely employed to answer questions about aging, behavior, cancer, growth,...
      Speaker: Marcus Crim, DVM
      Presented at: Laboratory Animal Sciences Virtual Event Series 2014
      46
      FEB 06, 2014 | 12:00 PM
      C.E. CREDITS
      Real Experience = Real Results: Tips and Strategies for the Delivery of Effective Safety Training Programs
      Real Experience = Real Results: Tips and Strategies for the Delivery...
      All trainers are people but not all people are trainers. Several factors beyond the trainer influence the effectiveness of a safety training programs. This program will discuss the critical...
      Speaker: Sean Kaufman, MPH, CIC, CPH, CHES
      Presented at: Laboratory Animal Sciences Virtual Event Series 2014
      12
      FEB 06, 2014 | 10:00 AM
      Zebrafish Husbandry Education Efforts by GSCC, UAB, and a Community of Scholars
      Zebrafish Husbandry Education Efforts by GSCC, UAB, and a Community...
      A problem facing the rapid growth of zebrafish as a model for human disease is a lack of qualified personnel that understand the benefits and limitations of fish culture. As this model gains...
      Speaker: Hugh Hammer, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2014
      0
      FEB 06, 2014 | 6:00 AM
      Use of Dried Blood Spot Samples in Serological Testing of Rodents
      Use of Dried Blood Spot Samples in Serological Testing of Rodents
      The utility of dried blood spot (DBS) sampling technology for rodent colony health monitoring was investigated using a two-tiered approach. In the first approach, groups of mice and rats were...
      Speaker: Matthew H Myles, DVM, PhD, DACLAM
      Presented at: Laboratory Animal Sciences Virtual Event Series 2014
      0
      FEB 05, 2014 | 2:00 PM
      Guidelines for Inanimate Surgical Training and Competency Assessment; Improvement of Animal Welfare and Decreasing Confounding Factors
      Guidelines for Inanimate Surgical Training and Competency Assessment;...
      With the growth and expansion of mouse and rat transgenic models in recent years, the demand for surgically altered models mimicking human diseases is growing at an amazing rate. Surgical pro...
      Speaker: Szczepan Baran, VMD, MS
      Presented at: Laboratory Animal Sciences Virtual Event Series 2014
      0
      OCT 16, 2013 | 11:00 AM
      C.E. CREDITS
      Embracing Complexity: Drosophila as a Tool to Develop Cancer Therapeutics
      Embracing Complexity: Drosophila as a Tool to Develop Cancer Therapeutics
      Cancer and diabetes are complex diseases that have proven difficult to treat in the clinics. Until recently, most efforts have focused on hitting individual therapeutic targets cleanly. Unfor...
      Speaker: Ross L. Cagan, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      78
      OCT 16, 2013 | 9:00 AM
      C.E. CREDITS
      Keynote: Breast Cancer Genomics and Genetics
      Keynote: Breast Cancer Genomics and Genetics
      It is now appreciated that breast cancer is not a single disease, but instead is a spectrum of tumor subtypes with distinct cellular origins, somatic changes and somewhat predictable clinical...
      Speaker: Charles M. Perou, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      132
      AUG 21, 2013 | 8:00 AM
      Post Genome-Wide Association Studies
      Post Genome-Wide Association Studies
      In this presentation I describe some of the approaches we are taking to identify the genetic architecture of common complex cancers with a particular focus on the etiology of lung cancer. Can...
      Speaker: Christopher I Amos, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2013
      105
    FEB 05, 2015 | 12:00 PM
    C.E. CREDITS
    The importance of pre-operative assessment and post-operative care in surgical procedures
    The importance of pre-operative assessment and post-operative...
    The pre-operative assessment and post-operative is critical for successful surgical procedures which will in turn lead to high quality outcomes in research studies. The care of the animals go...
    Speaker: Pilar Ariza Guzman, DVM, MS
    Presented at: Laboratory Animal Sciences Virtual Event Series 2015
    6
    FEB 04, 2015 | 1:30 PM
    C.E. CREDITS
    The Surgeons Toolbox: outcomes are only as good as the contents of the box
    The Surgeons Toolbox: outcomes are only as good as the contents...
    The field of surgical research has been growing rapidly with the development of new surgical and disease models. An extremely important and often overlooked aspect of creating these models is...
    Speaker: Szczepan Baran, VMD, MS
    Presented at: Laboratory Animal Sciences Virtual Event Series 2015
    4
    FEB 04, 2015 | 9:00 AM
    C.E. CREDITS
    Keynote: Applying Principles of Biosafety in Laboratory Animal Facilities
    Keynote: Applying Principles of Biosafety in Laboratory Animal...
    Some commonly accepted principles of biosafety include the strict adherence to standard laboratory practices and techniques, the use of safety equipment such as primary barriers and personal...
    Speaker: James R Swearengen, DVM
    Presented at: Laboratory Animal Sciences Virtual Event Series 2015
    14
    OCT 30, 2014 | 3:00 PM
    Clinical Shotgun Proteomics in Cancer Biomarker and Drug Target Research/Discovery
    Clinical Shotgun Proteomics in Cancer Biomarker and Drug Target...
    Mass spectrometry (MS)-based profiling of clinical specimens has been increasingly used in cancer research to characterize changes in protein expression between tumor and healthy tissue or be...
    Speaker: Josip Blonder, MD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    30
    SEP 24, 2014 | 2:00 PM
    Development and Applications of CRISPR-Cas9 for Genome Editing
    Development and Applications of CRISPR-Cas9 for Genome Editing
    The RNA-guided nuclease Cas9 from the microbial CRISPR adaptive immune system has emerged as an exciting tool for precise genome editing in eukaryotic cells. This presentation will discuss th...
    Speaker: Feng Zhang, Ph.D.
    Presented at: Advances in Drug Discovery and Development
    39
     
     
  • AUG 21, 2014 | 8:45 AM
    From Genetics to Genetic Medicine: Gene Therapy for vision restoration as a case study
    From Genetics to Genetic Medicine: Gene Therapy for vision restoration...
    Gene therapy for two forms of inherited retinal degeneration have met promising safety and efficacy endpoints in early stage clinical trials. These approaches made use of a replication defect...
    Speaker: Luk H Vandenberghe, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2014
    0
    MAY 29, 2014 | 10:30 AM
    Why are we unable to lose weight and keep it off? All about the connection between the gut and the brain
    Why are we unable to lose weight and keep it off? All about the...
    Obesity is a disease. It was once not considered to be a disease and to be a matter of will power and gluttony. It was also the case that we once thought that fat tissue had no metabolic func...
    Speaker: Caroline M Apovian, MD, FACP, FACN
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2014
    53
    MAR 20, 2014 | 1:00 PM
    The role of high throughput sequencing in the research and diagnosis of neurodegenerative disorders
    The role of high throughput sequencing in the research and diagnosis...
    Using high throughput next-generation sequencing to simultaneously search large number of genes for pathogenic mutations has numerous advantages. It decreases the pressure to narrow the dif...
    Speaker: Peter L Nagy, MD, PhD
    Presented at: Neuroscience Virtual Event Series 2014
    0
    MAR 20, 2014 | 6:00 AM
    Connectomics - Defining Neural Circuits to Understand Brain Function
    Connectomics - Defining Neural Circuits to Understand Brain Function
    Connectomics is a new field of research that aims to map the synapses of the nervous system in order to construct a wiring diagram of all the neural circuits. It is necessary to use the elect...
    Speaker: Scott W. Emmons, PhD
    Presented at: Neuroscience Virtual Event Series 2014
    54
    MAR 19, 2014 | 8:00 AM
    BRAIN Initiative Panel Discussion - science overview
    BRAIN Initiative Panel Discussion - science overview
    The Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative is part of a new Presidential focus aimed at revolutionizing our understanding of the human brain. By...
    Speaker: Emery N. Brown, MD, PhD, William Newsome, PhD, Justin Sanchez, PhD, Terrence J Sejnowski, PhD
    Presented at: Neuroscience Virtual Event Series 2014
    59
     
     
  • FEB 06, 2014 | 12:00 PM
    C.E. CREDITS
    Molecular Diagnostic Tests To Advance Health Monitoring of Laboratory Zebrafish
    Molecular Diagnostic Tests To Advance Health Monitoring of Laboratory...
    The zebrafish, Danio rerio, is an ideal model organism to address a broad array of biomedical questions, and is now widely employed to answer questions about aging, behavior, cancer, growth,...
    Speaker: Marcus Crim, DVM
    Presented at: Laboratory Animal Sciences Virtual Event Series 2014
    46
    FEB 06, 2014 | 12:00 PM
    C.E. CREDITS
    Real Experience = Real Results: Tips and Strategies for the Delivery of Effective Safety Training Programs
    Real Experience = Real Results: Tips and Strategies for the Delivery...
    All trainers are people but not all people are trainers. Several factors beyond the trainer influence the effectiveness of a safety training programs. This program will discuss the critical...
    Speaker: Sean Kaufman, MPH, CIC, CPH, CHES
    Presented at: Laboratory Animal Sciences Virtual Event Series 2014
    12
    FEB 06, 2014 | 10:00 AM
    Zebrafish Husbandry Education Efforts by GSCC, UAB, and a Community of Scholars
    Zebrafish Husbandry Education Efforts by GSCC, UAB, and a Community...
    A problem facing the rapid growth of zebrafish as a model for human disease is a lack of qualified personnel that understand the benefits and limitations of fish culture. As this model gains...
    Speaker: Hugh Hammer, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2014
    0
    FEB 06, 2014 | 6:00 AM
    Use of Dried Blood Spot Samples in Serological Testing of Rodents
    Use of Dried Blood Spot Samples in Serological Testing of Rodents
    The utility of dried blood spot (DBS) sampling technology for rodent colony health monitoring was investigated using a two-tiered approach. In the first approach, groups of mice and rats were...
    Speaker: Matthew H Myles, DVM, PhD, DACLAM
    Presented at: Laboratory Animal Sciences Virtual Event Series 2014
    0
    FEB 05, 2014 | 2:00 PM
    Guidelines for Inanimate Surgical Training and Competency Assessment; Improvement of Animal Welfare and Decreasing Confounding Factors
    Guidelines for Inanimate Surgical Training and Competency Assessment;...
    With the growth and expansion of mouse and rat transgenic models in recent years, the demand for surgically altered models mimicking human diseases is growing at an amazing rate. Surgical pro...
    Speaker: Szczepan Baran, VMD, MS
    Presented at: Laboratory Animal Sciences Virtual Event Series 2014
    0
     
     
  • OCT 16, 2013 | 11:00 AM
    C.E. CREDITS
    Embracing Complexity: Drosophila as a Tool to Develop Cancer Therapeutics
    Embracing Complexity: Drosophila as a Tool to Develop Cancer Therapeutics
    Cancer and diabetes are complex diseases that have proven difficult to treat in the clinics. Until recently, most efforts have focused on hitting individual therapeutic targets cleanly. Unfor...
    Speaker: Ross L. Cagan, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    78
    OCT 16, 2013 | 9:00 AM
    C.E. CREDITS
    Keynote: Breast Cancer Genomics and Genetics
    Keynote: Breast Cancer Genomics and Genetics
    It is now appreciated that breast cancer is not a single disease, but instead is a spectrum of tumor subtypes with distinct cellular origins, somatic changes and somewhat predictable clinical...
    Speaker: Charles M. Perou, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    132
    AUG 21, 2013 | 8:00 AM
    Post Genome-Wide Association Studies
    Post Genome-Wide Association Studies
    In this presentation I describe some of the approaches we are taking to identify the genetic architecture of common complex cancers with a particular focus on the etiology of lung cancer. Can...
    Speaker: Christopher I Amos, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2013
    105
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