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    Animal disease model development

    Animal disease models are non-human animals used to research strategies to detect, prevent, or treat human disease. A variety of animals, including mice, rats, rabbits, and non-human primates are used for animal disease modeling. New animal disease models are developed regularly as knowledge of disease expand and technological improvements enhance current models.

    Webinars

    • SEP 07, 2016 | 7:30 AM
      Keynote Speaker: Challenges towards a Universal Influenza Virus Vaccine
      Keynote Speaker: Challenges towards a Universal Influenza Virus...
      Despite FDA-approved vaccines and antivirals, seasonal and pandemic influenza remains a serious threat associated with substantial morbidity and mortality.  The present modalities and va...
      Speaker: Peter Palese, PhD
      Presented at: Microbiology & Immunology Virtual Event Series 2016
      3
      SEP 07, 2016 | 6:00 AM
      Invisible Influence: How the indoor microbiome influences health
      Invisible Influence: How the indoor microbiome influences health
      The human race, like all macrobiological life, evolved in a sea of microbes. There was no way to keep the bacterial and archaeal hoards at bay, so instead life evolved mechanisms to live with...
      Speaker: Jack Gilbert, PhD
      Presented at: Microbiology & Immunology Virtual Event Series 2016
      2
      AUG 30, 2016 | 8:00 AM
      Transplanted human stem cell-derived interneuron precursors mitigate mouse bladder dysfunction and central neuropathic pain after spinal cord injury
      Transplanted human stem cell-derived interneuron precursors mitigate...
      Neuropathic pain and bladder dysfunction represent significant quality of life issues for many spinal cord injury patients. Loss of GABAergic tone in the injured spinal cord may contribute to...
      Speaker: Cory Nicholas, PhD
      Presented at: 4th Annual 24 Hours of Stem Cells™ virtual event
      1
      AUG 30, 2016 | 8:00 AM
      Translating Pluripotent Stem Cell Therapies For Focal Brain Disorders
      Translating Pluripotent Stem Cell Therapies For Focal Brain Disorders
      A major challenge for the clinical application of pluripotent stem cell therapy for neurodegenerative diseases is large-scale manufacturing and cryopreservation of neurons and glia that can b...
      Speaker: Dustin Wakeman, PhD
      Presented at: 4th Annual 24 Hours of Stem Cells™ virtual event
      1
      AUG 24, 2016 | 8:00 AM
      Beyond Bone: Emerging Applications in Preclinical microCT Imaging
      Beyond Bone: Emerging Applications in Preclinical microCT Imaging
      DATE: August 24th 2016TIME:  8:00AM PST, 11:00AM ESTPreclinical micro-computed tomography (microCT) imaging systems are utilized across a wide range of applications requiring imagi...
      Speaker: Gael Rochefort, PhD , Chris Damoci
      Sponsored By: Revvity
      32
      JUN 23, 2016 | 11:00 AM
      Spotlights on T cells: new developments for translational and basic T cell research
      Spotlights on T cells: new developments for translational and...
      DATE:  June 23, 2016 TIME:  11:00am Pacific time, 2:00pm Eastern time T cells as part of the adaptive immune system play a central role in cell-mediated immunity. Their link to ...
      Speaker: Anne Richter, PhD
      Sponsored By: Miltenyi Biotec, Miltenyi Biotec
      6 1
      JUN 15, 2016 | 8:00 AM
      Novel  PET radiochemistries: Improving understanding and detection of disease
      Novel PET radiochemistries: Improving understanding and detection...
      DATE: June 15, 2016TIME:  08:00AM PDT, 11:00AM EDT, 3:00PM GMT Positron Emission Tomography (PET) is a 3-dimensional, quantitative imaging technology that has robust clinical trans...
      Speaker: Timothy DeGrado, PhD , Roger Schibli, PhD
      Sponsored By: Revvity
      32 1
      MAR 17, 2016 | 12:00 PM
      Keynote Speaker - Animal models in psychiatry research
      Keynote Speaker - Animal models in psychiatry research
      Schizophrenia, depression, bipolar disorder are all uniquely human conditions.  Psychiatric conditions include alterations in several different and overlapping domains (NIMH RDoC). Each...
      Speaker: Patricio O'Donnell, PhD
      Presented at: Neuroscience Virtual Event Series 2016
      2
      MAR 17, 2016 | 10:30 AM
      Promise and challenges of iPSC modeling in Parkinson's disease
      Promise and challenges of iPSC modeling in Parkinson's disease
      Given the challenges of replicating Parkinson’s disease in animal models, returning to models that are human-based and highly clinically characterized may provide the most successful pa...
      Speaker: Birgitt Schuele, MD
      Presented at: Neuroscience Virtual Event Series 2016
      2
      MAR 17, 2016 | 7:30 AM
      Featured Speaker - Friends with (Brain) Benefits: The impact of the gut microbiota on neurodevelopment and behaviour
      Featured Speaker - Friends with (Brain) Benefits: The impact of...
      There is a growing appreciation of the relationship between gut microbiota, and the host in maintaining homeostasis in health and predisposing to disease. Bacterial colonisation of the gut pl...
      Speaker: John Cryan, PhD
      Presented at: Neuroscience Virtual Event Series 2016
      4
      FEB 24, 2016 | 10:00 AM
      Harnessing the Power of Healthcare Data with Causal Machine Learning to drive Personalized and Effective Treatment Interventions
      Harnessing the Power of Healthcare Data with Causal Machine Learning...
      Every day, vast amounts of healthcare data are collected from clinical trials as well as real world medical visits on patient treatment regimens and subsequent clinical outcomes. This big dat...
      Speaker: Iya Khalil, PhD
      Presented at: Precision Medicine Virtual Event Series 2016
      2
      FEB 24, 2016 | 8:00 AM
      Keynote Presentation - Integrating the digital universe of data with consumer-driven mobile apps and large-scale panomics data to better understand, treat, and prevent disease
      Keynote Presentation - Integrating the digital universe of data...
      One of the primary goals of precision medicine is the aggregation and interpretation of deep, longitudinal patient-specific data in the context of the digital universe of information, using a...
      Speaker: Eric Schadt, PhD
      Presented at: Precision Medicine Virtual Event Series 2016
      2
      FEB 04, 2016 | 10:30 AM
      Stressed out! The consequences of environmentally induced stress on mouse models
      Stressed out! The consequences of environmentally induced stress...
      The environment has been found to be a major contributor to data variability and many aspects of the laboratory environment are stressful to rodents and do not accurately reflect the human ex...
      Speaker: Brianna Gaskill, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2016
      3
      FEB 04, 2016 | 6:00 AM
      Zebrafish: an upswing model in research and the need for refinement of anaesthesia
      Zebrafish: an upswing model in research and the need for refinement...
           In the last decade the number of publications in zebrafish tripled, from 938 in 2005 to 2432 in 2015 (Pubmed database; keyword: “zebrafish” in Title/Abstract;...
      Speaker: Ana Valentim, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2016
      2
      FEB 03, 2016 | 12:00 PM
      Evaluating the results of animal studies by means of Meta Analysis
      Evaluating the results of animal studies by means of Meta Analysis
      Animal studies still play a crucial role in research aimed at improving human health care. When performing animal studies, the results and their interpretation are not always straightforward....
      Speaker: Carlijn Hooijmans, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2016
      7
      FEB 03, 2016 | 10:30 AM
      Panel Discussion: Promoting reproducible animal research in journal publications
      Panel Discussion: Promoting reproducible animal research in journal...
      Reproducibility refers to the ability of an experiment or study to be replicated, either by the same person or group or by others working independently.  With regard to scientific public...
      Speaker: Linda Toth, DVM, PhD , Susan Compton
      Presented at: Laboratory Animal Sciences Virtual Event Series 2016
      2
      FEB 03, 2016 | 9:00 AM
      Keynote: Risks of Bias in in vivo research - and what to do about them
      Keynote: Risks of Bias in in vivo research - and what to do about...
      Translational failure in biomedicine has led to much soul-searching about the causes for this. Amongst many others (misunderstanding of statistical tests, vibration of effects, flexibility in...
      Speaker: Malcolm Macleod BSc(Hons) MBChB PhD FRCP Ed
      Presented at: Laboratory Animal Sciences Virtual Event Series 2016
      2
      DEC 08, 2015 | 8:00 AM
      WEBINAR: Advancing PD Cell Therapy: Transplanting Cryopreserved iPSC-derived Neurons
      WEBINAR: Advancing PD Cell Therapy: Transplanting Cryopreserved...
      December 8th, 2015 8:00 am PT, 10:00 am CT   Cryopreservation of post-mitotic, induced pluripotent stem cell-derived midbrain lineage dopamine neurons (iPSC-mDA) is a significant advan...
      Speaker: Dustin Wakeman, PhD
      Sponsored By: Cellular Dynamics, Cellular Dynamics
      9 3
      JUN 24, 2015 | 9:00 AM
      Solaris™ - A novel open-air fluorescence imaging system for image-guided surgery applications
      Solaris™ - A novel open-air fluorescence imaging system for image-guided...
      Date: Wednesday, June 24th, 2015 Time: 09:00AM PDT, 12:00PM EDT, 4:00PM GMT Solaris™ is a new open-air fluorescence imaging system developed by PerkinElmer, enabling translational in vivo pre...
      Speaker: Wael Yared, PhD , Jeffrey Peterson, PhD
      Sponsored By: Revvity
      12 1
      JUN 16, 2015 | 8:00 AM
      Employing new approaches to investigate human and mouse group 2 innate lymphoid cell responses
      Employing new approaches to investigate human and mouse group...
      Date: June 16, 2015Time: 8:00AM Pacific time, 11:00AM Eastern TimeGroup 2 innate lymphoid cells (ILC2s) are recently described innate immune cells that contribute to type 2 inflammation, tiss...
      Speaker: Elia Tait Wojno
      Sponsored By: eBioscience, an Affymetrix business, eBioscience, an Affymetrix business
      12
      JUN 11, 2015 | 7:00 AM
      The dynamics of β-amyloid plaque genesis - an in vivo study in transgenic mice of Alzheimer's disease
      The dynamics of β-amyloid plaque genesis - an in vivo study in...
      Date: Thursday, June 11th, 2015Time: 07:00AM PDT, 10:00AM EDT, 03:00PM BST Alzheimer's disease (AD) is the most common form of dementia with nearly 44 million people affected worldwide. Chara...
      Speaker: Steffen Burgold, PhD , Finn Peters
      Sponsored By: Andor, Andor
      14 1
      MAY 14, 2015 | 1:30 PM
      Epigenomic Profiles of Asthma
      Epigenomic Profiles of Asthma
      Asthma is heritable, influenced by the environment, and is modified by in utero exposures and aging; all of these features are also common to epigenetic regulation. Furthermore, genetic varia...
      Speaker: Ivana Yang, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2015
      2
      MAR 19, 2015 | 9:00 AM
      Keynote - Impulsivity and Compulsivity: Neural Substrates and Neuropsychiatric Implications
      Keynote - Impulsivity and Compulsivity: Neural Substrates and...
      Impulsivity can be defined as the tendency to act prematurely without foresight. Behavioural and neurobiological analysis of this construct, based on evidence from both animal and human studi...
      Speaker: Trevor Robbins, CBE FRS FMedSci FBPsS
      Presented at: Neuroscience Virtual Event Series 2015
      12
      MAR 18, 2015 | 12:00 PM
      Keynote - Psychosis as a Learning and Memory Disorder
      Keynote - Psychosis as a Learning and Memory Disorder
      The hippocampal formation is one of the most extensively studied regions of the brain, with well described anatomy and basic physiology; moreover, aspects of human memory mediated by hippocam...
      Speaker: Carol Tamminga, MD
      Presented at: Neuroscience Virtual Event Series 2015
      10
    SEP 07, 2016 | 7:30 AM
    Keynote Speaker: Challenges towards a Universal Influenza Virus Vaccine
    Keynote Speaker: Challenges towards a Universal Influenza Virus...
    Despite FDA-approved vaccines and antivirals, seasonal and pandemic influenza remains a serious threat associated with substantial morbidity and mortality.  The present modalities and va...
    Speaker: Peter Palese, PhD
    Presented at: Microbiology & Immunology Virtual Event Series 2016
    3
    SEP 07, 2016 | 6:00 AM
    Invisible Influence: How the indoor microbiome influences health
    Invisible Influence: How the indoor microbiome influences health
    The human race, like all macrobiological life, evolved in a sea of microbes. There was no way to keep the bacterial and archaeal hoards at bay, so instead life evolved mechanisms to live with...
    Speaker: Jack Gilbert, PhD
    Presented at: Microbiology & Immunology Virtual Event Series 2016
    2
    AUG 30, 2016 | 8:00 AM
    Transplanted human stem cell-derived interneuron precursors mitigate mouse bladder dysfunction and central neuropathic pain after spinal cord injury
    Transplanted human stem cell-derived interneuron precursors mitigate...
    Neuropathic pain and bladder dysfunction represent significant quality of life issues for many spinal cord injury patients. Loss of GABAergic tone in the injured spinal cord may contribute to...
    Speaker: Cory Nicholas, PhD
    Presented at: 4th Annual 24 Hours of Stem Cells™ virtual event
    1
    AUG 30, 2016 | 8:00 AM
    Translating Pluripotent Stem Cell Therapies For Focal Brain Disorders
    Translating Pluripotent Stem Cell Therapies For Focal Brain Disorders
    A major challenge for the clinical application of pluripotent stem cell therapy for neurodegenerative diseases is large-scale manufacturing and cryopreservation of neurons and glia that can b...
    Speaker: Dustin Wakeman, PhD
    Presented at: 4th Annual 24 Hours of Stem Cells™ virtual event
    1
    AUG 24, 2016 | 8:00 AM
    Beyond Bone: Emerging Applications in Preclinical microCT Imaging
    Beyond Bone: Emerging Applications in Preclinical microCT Imaging
    DATE: August 24th 2016TIME:  8:00AM PST, 11:00AM ESTPreclinical micro-computed tomography (microCT) imaging systems are utilized across a wide range of applications requiring imagi...
    Speaker: Gael Rochefort, PhD , Chris Damoci
    Sponsored By: Revvity
    32
     
     
  • JUN 23, 2016 | 11:00 AM
    Spotlights on T cells: new developments for translational and basic T cell research
    Spotlights on T cells: new developments for translational and...
    DATE:  June 23, 2016 TIME:  11:00am Pacific time, 2:00pm Eastern time T cells as part of the adaptive immune system play a central role in cell-mediated immunity. Their link to ...
    Speaker: Anne Richter, PhD
    Sponsored By: Miltenyi Biotec, Miltenyi Biotec
    6 1
    JUN 15, 2016 | 8:00 AM
    Novel  PET radiochemistries: Improving understanding and detection of disease
    Novel PET radiochemistries: Improving understanding and detection...
    DATE: June 15, 2016TIME:  08:00AM PDT, 11:00AM EDT, 3:00PM GMT Positron Emission Tomography (PET) is a 3-dimensional, quantitative imaging technology that has robust clinical trans...
    Speaker: Timothy DeGrado, PhD , Roger Schibli, PhD
    Sponsored By: Revvity
    32 1
    MAR 17, 2016 | 12:00 PM
    Keynote Speaker - Animal models in psychiatry research
    Keynote Speaker - Animal models in psychiatry research
    Schizophrenia, depression, bipolar disorder are all uniquely human conditions.  Psychiatric conditions include alterations in several different and overlapping domains (NIMH RDoC). Each...
    Speaker: Patricio O'Donnell, PhD
    Presented at: Neuroscience Virtual Event Series 2016
    2
    MAR 17, 2016 | 10:30 AM
    Promise and challenges of iPSC modeling in Parkinson's disease
    Promise and challenges of iPSC modeling in Parkinson's disease
    Given the challenges of replicating Parkinson’s disease in animal models, returning to models that are human-based and highly clinically characterized may provide the most successful pa...
    Speaker: Birgitt Schuele, MD
    Presented at: Neuroscience Virtual Event Series 2016
    2
    MAR 17, 2016 | 7:30 AM
    Featured Speaker - Friends with (Brain) Benefits: The impact of the gut microbiota on neurodevelopment and behaviour
    Featured Speaker - Friends with (Brain) Benefits: The impact of...
    There is a growing appreciation of the relationship between gut microbiota, and the host in maintaining homeostasis in health and predisposing to disease. Bacterial colonisation of the gut pl...
    Speaker: John Cryan, PhD
    Presented at: Neuroscience Virtual Event Series 2016
    4
     
     
  • FEB 24, 2016 | 10:00 AM
    Harnessing the Power of Healthcare Data with Causal Machine Learning to drive Personalized and Effective Treatment Interventions
    Harnessing the Power of Healthcare Data with Causal Machine Learning...
    Every day, vast amounts of healthcare data are collected from clinical trials as well as real world medical visits on patient treatment regimens and subsequent clinical outcomes. This big dat...
    Speaker: Iya Khalil, PhD
    Presented at: Precision Medicine Virtual Event Series 2016
    2
    FEB 24, 2016 | 8:00 AM
    Keynote Presentation - Integrating the digital universe of data with consumer-driven mobile apps and large-scale panomics data to better understand, treat, and prevent disease
    Keynote Presentation - Integrating the digital universe of data...
    One of the primary goals of precision medicine is the aggregation and interpretation of deep, longitudinal patient-specific data in the context of the digital universe of information, using a...
    Speaker: Eric Schadt, PhD
    Presented at: Precision Medicine Virtual Event Series 2016
    2
    FEB 04, 2016 | 10:30 AM
    Stressed out! The consequences of environmentally induced stress on mouse models
    Stressed out! The consequences of environmentally induced stress...
    The environment has been found to be a major contributor to data variability and many aspects of the laboratory environment are stressful to rodents and do not accurately reflect the human ex...
    Speaker: Brianna Gaskill, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2016
    3
    FEB 04, 2016 | 6:00 AM
    Zebrafish: an upswing model in research and the need for refinement of anaesthesia
    Zebrafish: an upswing model in research and the need for refinement...
         In the last decade the number of publications in zebrafish tripled, from 938 in 2005 to 2432 in 2015 (Pubmed database; keyword: “zebrafish” in Title/Abstract;...
    Speaker: Ana Valentim, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2016
    2
    FEB 03, 2016 | 12:00 PM
    Evaluating the results of animal studies by means of Meta Analysis
    Evaluating the results of animal studies by means of Meta Analysis
    Animal studies still play a crucial role in research aimed at improving human health care. When performing animal studies, the results and their interpretation are not always straightforward....
    Speaker: Carlijn Hooijmans, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2016
    7
     
     
  • FEB 03, 2016 | 10:30 AM
    Panel Discussion: Promoting reproducible animal research in journal publications
    Panel Discussion: Promoting reproducible animal research in journal...
    Reproducibility refers to the ability of an experiment or study to be replicated, either by the same person or group or by others working independently.  With regard to scientific public...
    Speaker: Linda Toth, DVM, PhD , Susan Compton
    Presented at: Laboratory Animal Sciences Virtual Event Series 2016
    2
    FEB 03, 2016 | 9:00 AM
    Keynote: Risks of Bias in in vivo research - and what to do about them
    Keynote: Risks of Bias in in vivo research - and what to do about...
    Translational failure in biomedicine has led to much soul-searching about the causes for this. Amongst many others (misunderstanding of statistical tests, vibration of effects, flexibility in...
    Speaker: Malcolm Macleod BSc(Hons) MBChB PhD FRCP Ed
    Presented at: Laboratory Animal Sciences Virtual Event Series 2016
    2
    DEC 08, 2015 | 8:00 AM
    WEBINAR: Advancing PD Cell Therapy: Transplanting Cryopreserved iPSC-derived Neurons
    WEBINAR: Advancing PD Cell Therapy: Transplanting Cryopreserved...
    December 8th, 2015 8:00 am PT, 10:00 am CT   Cryopreservation of post-mitotic, induced pluripotent stem cell-derived midbrain lineage dopamine neurons (iPSC-mDA) is a significant advan...
    Speaker: Dustin Wakeman, PhD
    Sponsored By: Cellular Dynamics, Cellular Dynamics
    9 3
    JUN 24, 2015 | 9:00 AM
    Solaris™ - A novel open-air fluorescence imaging system for image-guided surgery applications
    Solaris™ - A novel open-air fluorescence imaging system for image-guided...
    Date: Wednesday, June 24th, 2015 Time: 09:00AM PDT, 12:00PM EDT, 4:00PM GMT Solaris™ is a new open-air fluorescence imaging system developed by PerkinElmer, enabling translational in vivo pre...
    Speaker: Wael Yared, PhD , Jeffrey Peterson, PhD
    Sponsored By: Revvity
    12 1
    JUN 16, 2015 | 8:00 AM
    Employing new approaches to investigate human and mouse group 2 innate lymphoid cell responses
    Employing new approaches to investigate human and mouse group...
    Date: June 16, 2015Time: 8:00AM Pacific time, 11:00AM Eastern TimeGroup 2 innate lymphoid cells (ILC2s) are recently described innate immune cells that contribute to type 2 inflammation, tiss...
    Speaker: Elia Tait Wojno
    Sponsored By: eBioscience, an Affymetrix business, eBioscience, an Affymetrix business
    12
     
     
  • JUN 11, 2015 | 7:00 AM
    The dynamics of β-amyloid plaque genesis - an in vivo study in transgenic mice of Alzheimer's disease
    The dynamics of β-amyloid plaque genesis - an in vivo study in...
    Date: Thursday, June 11th, 2015Time: 07:00AM PDT, 10:00AM EDT, 03:00PM BST Alzheimer's disease (AD) is the most common form of dementia with nearly 44 million people affected worldwide. Chara...
    Speaker: Steffen Burgold, PhD , Finn Peters
    Sponsored By: Andor, Andor
    14 1
    MAY 14, 2015 | 1:30 PM
    Epigenomic Profiles of Asthma
    Epigenomic Profiles of Asthma
    Asthma is heritable, influenced by the environment, and is modified by in utero exposures and aging; all of these features are also common to epigenetic regulation. Furthermore, genetic varia...
    Speaker: Ivana Yang, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2015
    2
    MAR 19, 2015 | 9:00 AM
    Keynote - Impulsivity and Compulsivity: Neural Substrates and Neuropsychiatric Implications
    Keynote - Impulsivity and Compulsivity: Neural Substrates and...
    Impulsivity can be defined as the tendency to act prematurely without foresight. Behavioural and neurobiological analysis of this construct, based on evidence from both animal and human studi...
    Speaker: Trevor Robbins, CBE FRS FMedSci FBPsS
    Presented at: Neuroscience Virtual Event Series 2015
    12
    MAR 18, 2015 | 12:00 PM
    Keynote - Psychosis as a Learning and Memory Disorder
    Keynote - Psychosis as a Learning and Memory Disorder
    The hippocampal formation is one of the most extensively studied regions of the brain, with well described anatomy and basic physiology; moreover, aspects of human memory mediated by hippocam...
    Speaker: Carol Tamminga, MD
    Presented at: Neuroscience Virtual Event Series 2015
    10
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