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    Chromosome aberration

    Chromosome aberrations are changes in chromosome structure or number. Most aberrations are known as aneuploidies, or different numbers of chromosomes other than pairs (e.g., a trisomy is an aneuploidy with one extra chromosome and a monosomy has one fewer chromosome for a total of 1).

    Webinars

    • SEP 15, 2022 | 9:00 AM
      Advances and Challenges in Targeting Kinases in Cancer Therapeutics
      Advances and Challenges in Targeting Kinases in Cancer Therapeutics
      Date: September 15, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) Tyrosine kinases, a ubiquitous and diverse family of enzymes, are of considerable clinical interest because they dir...
      Speaker: Aishath Shanaz Naeem , Veronique Baron
      Sponsored By: BPS Bioscience
      9
      APR 22, 2021 | 12:00 AM
      An Introduction to Resources Facilitating Cancer Variant Interpretation
      An Introduction to Resources Facilitating Cancer Variant Interpretation
      Learning Objectives: 1. Identify different kinds of genomic resources 2. Learn to apply the features available in genomic resources to cancer variant interpretation 3. Describe the importanc...
      Speaker: Beth Pitel, M.S., CG(ASCP)CM
      Presented at: Genetics Week Virtual Event Series 2021
      2
      JUL 29, 2020 | 1:00 PM
      Using quantitative imaging microscopy to explore and target the molecular origins of cancer
      Using quantitative imaging microscopy to explore and target the...
      The identification of novel drug targets and the development of next generation therapeutic strategies remain elusive goals for cancer researchers. We believe that the aberrant molecular eve...
      Speaker: Kirk McManus, PhD
      Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
      1
      JUN 26, 2020 | 8:00 AM
      Next-Generation Cytogenetics: international, multi-center study of chromosomal aberrations in constitutional diseases and leukemia with Bionano genome imaging
      Next-Generation Cytogenetics: international, multi-center study...
      DATE: June 26, 2020 TIME: 8:00am PT Structural variants (SVs) are an important source of genetic variation in the human genome and they are involved in a multitude of human diseases as well...
      Speaker: Alexander Hoischen , Laila El Khattabi
      Sponsored By: Bionano
      16
      NOV 28, 2018 | 7:00 AM
      Discover how single-cell RNA sequencing provides deeper insights into lung cancer biology
      Discover how single-cell RNA sequencing provides deeper insights...
      DATE: November 28, 2018TIME:  7:00AM PSTSingle-cell genomics enables a deep dive into the mechanisms responsible for health and disease, in areas from cancer biology to neurob...
      Speaker: Bernard Thienpont , Annika Branting , Pawel Zajac, Ph.D.
      Sponsored By: Illumina, 10x Genomics
      5
      OCT 16, 2018 | 7:00 AM
      On the right track: building the neural circuitry for feeding and swallowing
      On the right track: building the neural circuitry for feeding...
      DATE:  October 16, 2018TIME:  7:00m PDT, 10:00am EDT 22q11 Deletion Syndrome (22q11DS) is a genomic disorder caused by a microdeletion of chromosome 22 that occurs...
      Speaker: Zahra Motahari, PhD
      Sponsored By: Leica Microsystems
      5
      AUG 09, 2018 | 8:00 AM
      Exon-level array: Bridging the gap between chromosomal microarray and next-gen sequencing
      Exon-level array: Bridging the gap between chromosomal microarray...
      DATE:  August 9, 2018TIME:  8:00am PDT, 11:00am EDT Current exon-level arrays and NGS techniques for CNV detection are plagued with a high number of false-positive...
      Speaker: Nicole de Leeuw, PhD , Kristina Cusmano-Ozog, MD
      Sponsored By: Thermo Fisher Scientific - Applied Biosystems
      9
      JAN 18, 2018 | 8:00 AM
      Unravel the exome odyssey: overcome the challenges of exon-level CNV detection
      Unravel the exome odyssey: overcome the challenges of exon-level...
      Current exon-level arrays and NGS techniques for CNV detection are plagued with a high number of false-positive calls and are challenging...
      Speaker: Alka Chaubey, PhD, FACMG , Kristina Cusmano-Ozog, MD
      Sponsored By: Thermo Fisher Scientific - Applied Biosystems
      8
      DEC 05, 2017 | 10:00 AM
      WEBINAR: Pathologist's Perspective: Limitations and Benefits of Immunofixation and Immunotyping for Monoclonal Gammopathy Characterization
      WEBINAR: Pathologist's Perspective: Limitations and Benefits of...
      DATE: December 5, 2017TIME: 10:00AM PT, 1:00PM ET Monoclonal Gammopathies (MG) are characterized by chromosomal aberration of B-cells or plasma cells resulting in benign or mal...
      Speaker: Daniel Hood, MD
      Sponsored By: Sebia, Inc.
      10
      MAR 21, 2017 | 10:00 AM
      WEBINAR: Application of combined RNA in situ hybridization and multiplex immunohistochemistry to unravel tumor heterogeneity in prostate cancer
      WEBINAR: Application of combined RNA in situ hybridization and...
      DATE: March 21, 2017TIME: 10:00am PT, 1:00pm ETSponsored By:      Prostate cancer is a complex disease with multiple tumors originating independent...
      Speaker: Nallasivam Palanisamy, PhD , Courtney Anderson, PhD
      Sponsored By: Novus Biologicals a Bio-Techne Brand
      20 9
      SEP 16, 2014 | 10:00 AM
      Expanded clinical research opportunities for Crizotinib identified from an analysis of over 5,000 exomes
      Expanded clinical research opportunities for Crizotinib identified...
      Patients with chromosomal rearrangements resulting in fusion proteins are among the most responsive to published targeted therapy. For example, targeting of the EML4-ALK fusion in non-small c...
      Speaker: Sean Eddy, PhD
      Presented at: Advanced Genomics in Clinical and Translational Research - Informing end-to-end cancer drug development with bioinformatics
      12
      AUG 20, 2014 | 8:00 AM
      Exploring Complex Structural Genomic Variation using Next-Gen Sequencing
      Exploring Complex Structural Genomic Variation using Next-Gen...
      Structural variants (SVs), defined as the deletion, duplication, insertion, inversion or translocation of genomic regions, are both a major source of genetic diversity in human populations an...
      Speaker: Ryan E. Mills, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2014
      12
      OCT 16, 2013 | 1:00 PM
      C.E. CREDITS
      Molecular Diagnostics in Detection, Diagnosis, and Prognosis of Cancer
      Molecular Diagnostics in Detection, Diagnosis, and Prognosis of...
      Cancer cells have historically been classified by microscopic analysis of blood smears and tissue sections. Current technologies use molecular techniques to categorize and classify tumor cell...
      Speaker: Kristin Landis-Piwowar, PhD, MLS
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      129
    SEP 15, 2022 | 9:00 AM
    Advances and Challenges in Targeting Kinases in Cancer Therapeutics
    Advances and Challenges in Targeting Kinases in Cancer Therapeutics
    Date: September 15, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) Tyrosine kinases, a ubiquitous and diverse family of enzymes, are of considerable clinical interest because they dir...
    Speaker: Aishath Shanaz Naeem , Veronique Baron
    Sponsored By: BPS Bioscience
    9
    APR 22, 2021 | 12:00 AM
    An Introduction to Resources Facilitating Cancer Variant Interpretation
    An Introduction to Resources Facilitating Cancer Variant Interpretation
    Learning Objectives: 1. Identify different kinds of genomic resources 2. Learn to apply the features available in genomic resources to cancer variant interpretation 3. Describe the importanc...
    Speaker: Beth Pitel, M.S., CG(ASCP)CM
    Presented at: Genetics Week Virtual Event Series 2021
    2
    JUL 29, 2020 | 1:00 PM
    Using quantitative imaging microscopy to explore and target the molecular origins of cancer
    Using quantitative imaging microscopy to explore and target the...
    The identification of novel drug targets and the development of next generation therapeutic strategies remain elusive goals for cancer researchers. We believe that the aberrant molecular eve...
    Speaker: Kirk McManus, PhD
    Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
    1
    JUN 26, 2020 | 8:00 AM
    Next-Generation Cytogenetics: international, multi-center study of chromosomal aberrations in constitutional diseases and leukemia with Bionano genome imaging
    Next-Generation Cytogenetics: international, multi-center study...
    DATE: June 26, 2020 TIME: 8:00am PT Structural variants (SVs) are an important source of genetic variation in the human genome and they are involved in a multitude of human diseases as well...
    Speaker: Alexander Hoischen , Laila El Khattabi
    Sponsored By: Bionano
    16
    NOV 28, 2018 | 7:00 AM
    Discover how single-cell RNA sequencing provides deeper insights into lung cancer biology
    Discover how single-cell RNA sequencing provides deeper insights...
    DATE: November 28, 2018TIME:  7:00AM PSTSingle-cell genomics enables a deep dive into the mechanisms responsible for health and disease, in areas from cancer biology to neurob...
    Speaker: Bernard Thienpont , Annika Branting , Pawel Zajac, Ph.D.
    Sponsored By: Illumina, 10x Genomics
    5
     
     
  • OCT 16, 2018 | 7:00 AM
    On the right track: building the neural circuitry for feeding and swallowing
    On the right track: building the neural circuitry for feeding...
    DATE:  October 16, 2018TIME:  7:00m PDT, 10:00am EDT 22q11 Deletion Syndrome (22q11DS) is a genomic disorder caused by a microdeletion of chromosome 22 that occurs...
    Speaker: Zahra Motahari, PhD
    Sponsored By: Leica Microsystems
    5
    AUG 09, 2018 | 8:00 AM
    Exon-level array: Bridging the gap between chromosomal microarray and next-gen sequencing
    Exon-level array: Bridging the gap between chromosomal microarray...
    DATE:  August 9, 2018TIME:  8:00am PDT, 11:00am EDT Current exon-level arrays and NGS techniques for CNV detection are plagued with a high number of false-positive...
    Speaker: Nicole de Leeuw, PhD , Kristina Cusmano-Ozog, MD
    Sponsored By: Thermo Fisher Scientific - Applied Biosystems
    9
    JAN 18, 2018 | 8:00 AM
    Unravel the exome odyssey: overcome the challenges of exon-level CNV detection
    Unravel the exome odyssey: overcome the challenges of exon-level...
    Current exon-level arrays and NGS techniques for CNV detection are plagued with a high number of false-positive calls and are challenging...
    Speaker: Alka Chaubey, PhD, FACMG , Kristina Cusmano-Ozog, MD
    Sponsored By: Thermo Fisher Scientific - Applied Biosystems
    8
    DEC 05, 2017 | 10:00 AM
    WEBINAR: Pathologist's Perspective: Limitations and Benefits of Immunofixation and Immunotyping for Monoclonal Gammopathy Characterization
    WEBINAR: Pathologist's Perspective: Limitations and Benefits of...
    DATE: December 5, 2017TIME: 10:00AM PT, 1:00PM ET Monoclonal Gammopathies (MG) are characterized by chromosomal aberration of B-cells or plasma cells resulting in benign or mal...
    Speaker: Daniel Hood, MD
    Sponsored By: Sebia, Inc.
    10
    MAR 21, 2017 | 10:00 AM
    WEBINAR: Application of combined RNA in situ hybridization and multiplex immunohistochemistry to unravel tumor heterogeneity in prostate cancer
    WEBINAR: Application of combined RNA in situ hybridization and...
    DATE: March 21, 2017TIME: 10:00am PT, 1:00pm ETSponsored By:      Prostate cancer is a complex disease with multiple tumors originating independent...
    Speaker: Nallasivam Palanisamy, PhD , Courtney Anderson, PhD
    Sponsored By: Novus Biologicals a Bio-Techne Brand
    20 9
     
     
  • SEP 16, 2014 | 10:00 AM
    Expanded clinical research opportunities for Crizotinib identified from an analysis of over 5,000 exomes
    Expanded clinical research opportunities for Crizotinib identified...
    Patients with chromosomal rearrangements resulting in fusion proteins are among the most responsive to published targeted therapy. For example, targeting of the EML4-ALK fusion in non-small c...
    Speaker: Sean Eddy, PhD
    Presented at: Advanced Genomics in Clinical and Translational Research - Informing end-to-end cancer drug development with bioinformatics
    12
    AUG 20, 2014 | 8:00 AM
    Exploring Complex Structural Genomic Variation using Next-Gen Sequencing
    Exploring Complex Structural Genomic Variation using Next-Gen...
    Structural variants (SVs), defined as the deletion, duplication, insertion, inversion or translocation of genomic regions, are both a major source of genetic diversity in human populations an...
    Speaker: Ryan E. Mills, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2014
    12
    OCT 16, 2013 | 1:00 PM
    C.E. CREDITS
    Molecular Diagnostics in Detection, Diagnosis, and Prognosis of Cancer
    Molecular Diagnostics in Detection, Diagnosis, and Prognosis of...
    Cancer cells have historically been classified by microscopic analysis of blood smears and tissue sections. Current technologies use molecular techniques to categorize and classify tumor cell...
    Speaker: Kristin Landis-Piwowar, PhD, MLS
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    129
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