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    Drug Discovery

    Drug Discovery: drug discovery is the process by which new candidate medications are discovered. Historically, drugs were discovered through identifying the active ingredient from traditional remedies or by serendipitous discovery. Modern drug discovery involves the identification of screening hits, medicinal chemistry and optimization of those hits to increase the affinity, selectivity (to reduce the potential of side effects), efficacy/potency, metabolic stability (to increase the half-life), and oral bioavailability.

    Trending News

    • MAR 13, 2023
      Drug Discovery & Development
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      Combating the global antibiotic resistance with an unexpected creature: maggots
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      MAR 13, 2023
      Drug Discovery & Development
      A Promising New Chemical Compound to Treat Autoimmune Diseases like Multiple sclerosis and Rheumatoid Arthritis
      A Promising New Chemical Compound to Treat Autoimmune Diseases like Multiple sclerosis and Rheumatoid Arthritis
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      MAR 13, 2023
      Cancer
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      MAR 12, 2023
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      Experimental Anti-amyloid Treatment Fails to Slow Cognitive Decline
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      MAR 11, 2023
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      Using blood pressure medications to treat diabetes: how does it work?
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      MAR 10, 2023
      Health & Medicine
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      In a First, an mRNA Vaccine for a Deadly Bacterium is Created
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      MAR 09, 2023
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      MAR 08, 2023
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      CBD May Increase THC's Adverse Effects in Edible Cannabis Products
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      MAR 07, 2023
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      FDA mandate decreased acetaminophen liver failure
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      MAR 06, 2023
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      Drug Combo Best for Older Adults with Treatment-Resistant Depression
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      MAR 05, 2023
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      MAR 05, 2023
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      New Anti-diabetic Drug May Reduce Risk for Respiratory and Renal Conditions
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      MAR 03, 2023
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      MAR 02, 2023
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      MAR 02, 2023
      Neuroscience
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      MAR 01, 2023
      Drug Discovery & Development
      FDA Committee Votes in Favor of Pfizer's RSV Vaccine
      FDA Committee Votes in Favor of Pfizer's RSV Vaccine
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      FEB 27, 2023
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      FEB 27, 2023
      Cancer
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      FEB 25, 2023
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      Scientists Discover a "Thermal Cortex" in the Posterior Brain Region
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      What happens in our brains when reaching for that hot latte or cold milkshake? Researchers from the Max Delbrück Ce ...
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      FEB 24, 2023
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      First and Only Treatment for Preventing Leading Cause of Blindness
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      FEB 24, 2023
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      FEB 23, 2023
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    MAR 13, 2023
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    Combating the global antibiotic resistance with an unexpected creature: maggots
    Antibiotics are a great class of drugs used to treat a variety of infections.1 However, the bacterial life cycle is much ...
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    3
    MAR 13, 2023
    Drug Discovery & Development
    A Promising New Chemical Compound to Treat Autoimmune Diseases like Multiple sclerosis and Rheumatoid Arthritis
    A Promising New Chemical Compound to Treat Autoimmune Diseases like Multiple sclerosis and Rheumatoid Arthritis
    A team of researchers from the Okinawa Institute of Science and Technology (OIST) have developed a new chemical compound ...
    Written By: Laurence Tognetti, MSc
    7
    MAR 13, 2023
    Cancer
    New Data from Lung Cancer Immunotherapy Clinical Trial Released
    New Data from Lung Cancer Immunotherapy Clinical Trial Released
    Immune checkpoint inhibitor (ICI) therapy has revolutionized the cancer treatment landscape providing treatment options ...
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    4
    MAR 12, 2023
    Drug Discovery & Development
    Experimental Anti-amyloid Treatment Fails to Slow Cognitive Decline
    Experimental Anti-amyloid Treatment Fails to Slow Cognitive Decline
    Experimental anti-amyloid treatment, solanezumab, did not significantly slow Alzheimer’s disease (AD)-related cogn ...
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    3
    MAR 11, 2023
    Drug Discovery & Development
    Using blood pressure medications to treat diabetes: how does it work?
    Using blood pressure medications to treat diabetes: how does it work?
    Type 1 Diabetes Mellitus (T1DM) is a condition where the pancreas makes little to no insulin.1 Insulin is a type of ...
    Written By: Greta Anne
    2
     
     
  • MAR 10, 2023
    Health & Medicine
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    In a First, an mRNA Vaccine for a Deadly Bacterium is Created
    While the world became very familiar with mRNA vaccines because of the COVID-19 pandemic, mRNA vaccines have been around ...
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    3
    MAR 09, 2023
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    Immunotherapy Duo Eliminates Metastatic Breast Cancer in Mice
    Immunotherapy Duo Eliminates Metastatic Breast Cancer in Mice
    Researchers investigated a two-pronged immunotherapy approach that eliminates metastatic breast cancer in mice. The corr ...
    Written By: Annie Lennon
    2
    MAR 08, 2023
    Cancer
    Why Automation is Outpacing Traditional Methods for Single-Cell Cloning
    Why Automation is Outpacing Traditional Methods for Single-Cell Cloning
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    3
    MAR 08, 2023
    Cannabis Sciences
    CBD May Increase THC's Adverse Effects in Edible Cannabis Products
    CBD May Increase THC's Adverse Effects in Edible Cannabis Products
    A recent Johns Hopkins University School of Medicine study found that relatively high doses of cannabidiol (CBD) may int ...
    Written By: Kerry Charron
    3
    MAR 07, 2023
    Health & Medicine
    FDA mandate decreased acetaminophen liver failure
    FDA mandate decreased acetaminophen liver failure
    In 2011 the FDA limited the milligrams of acetaminophen in opioid medications. Now, a new study out of JAMA has the resu ...
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    2
     
     
  • MAR 07, 2023
    Neuroscience
    Save the Date! Labroots to Host 11th Annual Neuroscience Virtual Event Series, March 8th, 2023
    Save the Date! Labroots to Host 11th Annual Neuroscience Virtual Event Series, March 8th, 2023
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    5
    MAR 06, 2023
    Drug Discovery & Development
    Drug Combo Best for Older Adults with Treatment-Resistant Depression
    Drug Combo Best for Older Adults with Treatment-Resistant Depression
    Adding an antipsychotic or antidepressant drug to pre-existing antidepressant treatment is more effective than switching ...
    Written By: Annie Lennon
    2
    MAR 05, 2023
    Immunology
    Digital Twins Provide Insight Into Inflammatory Disease Treatment
    Digital Twins Provide Insight Into Inflammatory Disease Treatment
    The immune system is incredibly complex, and there are many different signaling molecules and receptors that can dial in ...
    Written By: Carmen Leitch
    1
    MAR 05, 2023
    Drug Discovery & Development
    New Anti-diabetic Drug May Reduce Risk for Respiratory and Renal Conditions
    New Anti-diabetic Drug May Reduce Risk for Respiratory and Renal Conditions
    A new antidiabetic drug may reduce the risk of respiratory and renal conditions, including end-stage renal disease and p ...
    Written By: Annie Lennon
    2
    MAR 03, 2023
    Health & Medicine
    How Bacteria Enter the Brain to Cause Meningitis
    How Bacteria Enter the Brain to Cause Meningitis
    Infections with many different types of bacteria including Streptococcus pneumonia and Listeria monocytogens can cause b ...
    Written By: Carmen Leitch
    2
     
     
  • MAR 02, 2023
    Drug Discovery & Development
    Allergy Desensitization: How We Can Phase Out 'Peanut-Free' Tables at School
    Allergy Desensitization: How We Can Phase Out 'Peanut-Free' Tables at School
    Peanut allergies affect roughly 6.1 million Americans, and over 32 million have more general allergies.1 Many of these p ...
    Written By: Greta Anne
    1
    MAR 02, 2023
    Neuroscience
    Study Examines Electrodes Grown in the Brain
    Study Examines Electrodes Grown in the Brain
    Researchers in Sweden have cultivated electrodes in living brain tissue using the body’s molecules. The body&rsquo ...
    Written By: Kerry Charron
    1
    MAR 01, 2023
    Drug Discovery & Development
    FDA Committee Votes in Favor of Pfizer's RSV Vaccine
    FDA Committee Votes in Favor of Pfizer's RSV Vaccine
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    Written By: Greta Anne
    3
    FEB 27, 2023
    Drug Discovery & Development
    Night of pleasure leads to sexual infection drug discovery
    Night of pleasure leads to sexual infection drug discovery
    A new drug shows the potential to treat an exceptionally resilient sexual infection.    A case study from the ...
    Written By: Amielle Moreno
    4
    FEB 27, 2023
    Cancer
    Safety of an AHR Inhibitor Demonstrated in Early Phase Clinical Trial
    Safety of an AHR Inhibitor Demonstrated in Early Phase Clinical Trial
    A study presented in November at the Society for Immunotherapy of Cancer 37th Annual Meeting and published in the Journa ...
    Written By: Katie Kokolus
    2
     
     
  • FEB 25, 2023
    Neuroscience
    Scientists Discover a "Thermal Cortex" in the Posterior Brain Region
    Scientists Discover a "Thermal Cortex" in the Posterior Brain Region
    What happens in our brains when reaching for that hot latte or cold milkshake? Researchers from the Max Delbrück Ce ...
    Written By: Kerry Charron
    1
    FEB 24, 2023
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    First and Only Treatment for Preventing Leading Cause of Blindness
    Geographic atrophy (GA) sounds like it is related to geography - which it is - geography of the eye. GA is an irreversib ...
    Written By: Greta Anne
    1
    FEB 24, 2023
    Drug Discovery & Development
    New nanomaterial discovered that can enhance disinfectant potency
    New nanomaterial discovered that can enhance disinfectant potency
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    FEB 23, 2023
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