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Drug Discovery
Drug Discovery: drug discovery is the process by which new candidate medications are discovered. Historically, drugs were discovered through identifying the active ingredient from traditional remedies or by serendipitous discovery. Modern drug discovery involves the identification of screening hits, medicinal chemistry and optimization of those hits to increase the affinity, selectivity (to reduce the potential of side effects), efficacy/potency, metabolic stability (to increase the half-life), and oral bioavailability.
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JUN 04, 2024Neuroscience
A meta-analysis published in Journal of the American Academy of Child and Adolescent Psychiatry sought to explore the ef ...Written By: Greta AnneJUN 04, 2024Drug Discovery & Development
Moderate-vigorous intensity exercise could improve the efficacy of antibody therapies when treating leukemia. The corres ...Written By: Annie LennonJUN 04, 2024Drug Discovery & Development
The long journey from cell culture to a purified monoclonal antibody (mAb) involves many sample processing steps, with c ...JUN 03, 2024eBooksThis application note highlights a study that evaluates the use of Sartoclear Dynamics® Lab Filter Aid, containing d ...JUN 03, 2024Neuroscience
Female rats given synthetic estrogen found in birth control exhibited more anxiety-like behaviors than those given natur ...Written By: Annie LennonJUN 03, 2024Neuroscience
A new study found that SSRIs may be able to help other drugs cross the blood-brain barrier. The findings could aid the d ...Written By: Annie LennonMAY 30, 2024eBooksProteins possess diverse conformations, some pivotal in disease pathology. Protein misfolding and aggregation are linked ...Sponsored By: Quantum-SiMAY 30, 2024Immunology
Chimeric antigen receptor (CAR) T cells are a form of immunotherapy in which T cells, a type of immune cell, is engineer ...Written By: Brian G. MorrealeMAY 30, 2024Cell & Molecular Biology
For many years, the efficacy of many front-line antibiotics has been declining because of the spread of antibiotic resis ...Written By: Carmen LeitchMAY 30, 2024Genetics & Genomics
With advances in genomics research, personalized medicine, and sequencing-based technologies, there is a necessity for p ...Sponsored By: Omega Bio-tekMAY 30, 2024Cancer
Oncologists base prognosis, the predicted long-term outcome of an individual’s cancer, on the chances of recovery ...Written By: Katie KokolusMAY 29, 2024Microbiology
The Epstein-Barr virus (EBV) is known to cause a wide variety of diseases, including various types of cancer and multipl ...Written By: Carmen LeitchMAY 28, 2024Drug Discovery & Development
People who use metformin are less likely to develop a group of rare blood cancers over time. The corresponding study was ...Written By: Annie LennonMAY 28, 2024Drug Discovery & Development
A study published in Diabetes Care, a journal of the American Diabetes Association investigates the impact of the timing ...Written By: Greta AnneMAY 27, 2024Drug Discovery & Development
Intracerebral hemorrhage (ICH) is a serious and often life-threatening condition, particularly in patients taking antico ...Written By: Greta AnneMAY 21, 2024Technology
Atrial fibrillation (AFib) is a prevalent cardiac arrhythmia associated with significant morbidity and mortality. C ...Written By: Greta AnneMAY 20, 2024Neuroscience
Oxytocin, commonly known as the ‘bonding’ or ‘cuddle’ hormone, can reduce acute feelings of ...Written By: Annie LennonMAY 20, 2024Plants & Animals
A study in the "Prevención con Dieta Mediterránea" (PREDIMED) trial was recently published in th ...Written By: Greta AnneMAY 16, 2024Cell & Molecular Biology
Proteins are often studied at very low temperatures. In the case of cryo-electron microscopy, for example, proteins are ...Written By: Carmen LeitchMAY 14, 2024eBooksNeurodegenerative conditions such as Alzheimer's and Parkinson's gradually destroy brain cells, leading to deter ...MAY 14, 2024Technology
The Population Assessment of Tobacco and Health (PATH) Study aims to understand the impact of tobacco and e-cigarette us ...Written By: Greta AnneMAY 13, 2024Neuroscience
The EMERGENT-3 trial, published in the Journal of the American Medical Association Psychiatry, represent ...Written By: Greta AnneMAY 13, 2024Microbiology
The gut microbiome contains trillions of microorganisms, which carry out a variety of activities. Not only do they expre ...Written By: Carmen LeitchMAY 13, 2024Cancer
Pancreatic ductal adenocarcinoma (PDAC) remains a highly aggressive and deadly disease with a poor prognosis. Deva ...Written By: Katie Kokolus
JUN 04, 2024
Neuroscience
A meta-analysis published in Journal of the American Academy of Child and Adolescent Psychiatry sought to explore the ef
...
Written By:
Greta Anne
JUN 04, 2024
Drug Discovery & Development
Moderate-vigorous intensity exercise could improve the efficacy of antibody therapies when treating leukemia. The corres
...
Written By:
Annie Lennon
JUN 04, 2024
Drug Discovery & Development
The long journey from cell culture to a purified monoclonal antibody (mAb) involves many sample processing steps, with c
...
JUN 03, 2024
eBooks
This application note highlights a study that evaluates the use of Sartoclear Dynamics® Lab Filter Aid, containing d
...
JUN 03, 2024
Neuroscience
Female rats given synthetic estrogen found in birth control exhibited more anxiety-like behaviors than those given natur
...
Written By:
Annie Lennon
JUN 03, 2024
Neuroscience
A new study found that SSRIs may be able to help other drugs cross the blood-brain barrier. The findings could aid the d
...
Written By:
Annie Lennon
MAY 30, 2024
eBooks
Proteins possess diverse conformations, some pivotal in disease pathology. Protein misfolding and aggregation are linked
...
Sponsored By:
Quantum-Si
MAY 30, 2024
Immunology
Chimeric antigen receptor (CAR) T cells are a form of immunotherapy in which T cells, a type of immune cell, is engineer
...
Written By:
Brian G. Morreale
MAY 30, 2024
Cell & Molecular Biology
For many years, the efficacy of many front-line antibiotics has been declining because of the spread of antibiotic resis
...
Written By:
Carmen Leitch
MAY 30, 2024
Genetics & Genomics
With advances in genomics research, personalized medicine, and sequencing-based technologies, there is a necessity for p
...
Sponsored By:
Omega Bio-tek
MAY 30, 2024
Cancer
Oncologists base prognosis, the predicted long-term outcome of an individual’s cancer, on the chances of recovery
...
Written By:
Katie Kokolus
MAY 29, 2024
Microbiology
The Epstein-Barr virus (EBV) is known to cause a wide variety of diseases, including various types of cancer and multipl
...
Written By:
Carmen Leitch
MAY 28, 2024
Drug Discovery & Development
People who use metformin are less likely to develop a group of rare blood cancers over time. The corresponding study was
...
Written By:
Annie Lennon
MAY 28, 2024
Drug Discovery & Development
A study published in Diabetes Care, a journal of the American Diabetes Association investigates the impact of the timing
...
Written By:
Greta Anne
MAY 27, 2024
Drug Discovery & Development
Intracerebral hemorrhage (ICH) is a serious and often life-threatening condition, particularly in patients taking antico
...
Written By:
Greta Anne
MAY 21, 2024
Technology
Atrial fibrillation (AFib) is a prevalent cardiac arrhythmia associated with significant morbidity and mortality. C
...
Written By:
Greta Anne
MAY 20, 2024
Neuroscience
Oxytocin, commonly known as the ‘bonding’ or ‘cuddle’ hormone, can reduce acute feelings of
...
Written By:
Annie Lennon
MAY 20, 2024
Plants & Animals
A study in the "Prevención con Dieta Mediterránea" (PREDIMED) trial was recently published in th
...
Written By:
Greta Anne
MAY 16, 2024
Cell & Molecular Biology
Proteins are often studied at very low temperatures. In the case of cryo-electron microscopy, for example, proteins are
...
Written By:
Carmen Leitch
MAY 14, 2024
eBooks
Neurodegenerative conditions such as Alzheimer's and Parkinson's gradually destroy brain cells, leading to deter
...
MAY 14, 2024
Technology
The Population Assessment of Tobacco and Health (PATH) Study aims to understand the impact of tobacco and e-cigarette us
...
Written By:
Greta Anne
MAY 13, 2024
Neuroscience
The EMERGENT-3 trial, published in the Journal of the American Medical Association Psychiatry, represent
...
Written By:
Greta Anne
MAY 13, 2024
Microbiology
The gut microbiome contains trillions of microorganisms, which carry out a variety of activities. Not only do they expre
...
Written By:
Carmen Leitch
MAY 13, 2024
Cancer
Pancreatic ductal adenocarcinoma (PDAC) remains a highly aggressive and deadly disease with a poor prognosis. Deva
...
Written By:
Katie Kokolus