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    Drug Discovery

    Drug Discovery: drug discovery is the process by which new candidate medications are discovered. Historically, drugs were discovered through identifying the active ingredient from traditional remedies or by serendipitous discovery. Modern drug discovery involves the identification of screening hits, medicinal chemistry and optimization of those hits to increase the affinity, selectivity (to reduce the potential of side effects), efficacy/potency, metabolic stability (to increase the half-life), and oral bioavailability.

    Trending News

    • OCT 14, 2022
      Drug Discovery & Development
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      Experimental Gene Therapy Restores Night Vision in Blind Patients
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      OCT 13, 2022
      Neuroscience
      A Newly Discovered Function of the Cerebellum
      A Newly Discovered Function of the Cerebellum
      The cerebellum is primarily involved in movement, but a recent study found that the cerebellum is also involved in remem ...
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      OCT 13, 2022
      Technology
      Robotic Pill Effective for Oral Delivery of Medications Like Insulin
      Robotic Pill Effective for Oral Delivery of Medications Like Insulin
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      OCT 13, 2022
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      High Doses of CBD Safe for Driving
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      OCT 12, 2022
      Cannabis Sciences
      Cannabis Use for Menopausal Symptoms
      Cannabis Use for Menopausal Symptoms
      A study published in Menopause found that women are increasingly using medical cannabis to alleviate menopause-related s ...
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      OCT 12, 2022
      Plants & Animals
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      New Antimicrobial Discovered in Bacteria That Infects Potatoes
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      OCT 12, 2022
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      Cavity-Causing Germs Can Form Superorganisms Able to Crawl on Teeth
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      OCT 12, 2022
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      A Coach's Authentic Leadership has a Positive Effect on Athletes
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      OCT 11, 2022
      Clinical & Molecular DX
      Researchers Discover Method of Synthesizing a Cancer Drug Discovered in the Australian Rainforest
      Researchers Discover Method of Synthesizing a Cancer Drug Discovered in the Australian Rainforest
      Tigilanol tiglate (also referred to as EBC-46) is a chemical compound with a storied history. Found naturally in the see ...
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      OCT 10, 2022
      Clinical & Molecular DX
      Scripps and Moderna Scientists Propose an HIV Vaccine Based on mRNA Technology
      Scripps and Moderna Scientists Propose an HIV Vaccine Based on mRNA Technology
      A new report published in the Journal Immunity describes an approach to developing an effective vaccine against human im ...
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      OCT 10, 2022
      Cancer
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      OCT 09, 2022
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      OCT 07, 2022
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      A wearable sensor that can monitor tumor size changes in real-time
      A wearable sensor that can monitor tumor size changes in real-time
      As cancer drugs are developed, one important process the drug goes through is testing in experimental animals. The use o ...
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      OCT 06, 2022
      Chemistry & Physics
      2022 Nobel Prize in Chemistry
      2022 Nobel Prize in Chemistry
      It’s that time of year again! Three scientists, Carolyn R. Bertozzi, Morten Meldal, and K. Barry Sharpless, were a ...
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      OCT 05, 2022
      Technology
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      OCT 05, 2022
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      OCT 04, 2022
      Cancer
      The NCI Welcomes First Woman Director: Monica M. Bertagnolli, MD
      The NCI Welcomes First Woman Director: Monica M. Bertagnolli, MD
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      OCT 03, 2022
      Plants & Animals
      Yeast Proteins Could Provide Clues for New Antifungal Development
      Yeast Proteins Could Provide Clues for New Antifungal Development
      Yeast, like bacteria, causes infections. In fact, yeasts are responsible for over 100 million infections every year. The ...
      Written By: Ryan Vingum
      1
      OCT 03, 2022
      Clinical & Molecular DX
      Could Blood Samples Detect the Risk of Peripheral Neuropathy in Type 2 Diabetes?
      Could Blood Samples Detect the Risk of Peripheral Neuropathy in Type 2 Diabetes?
      Type 2 diabetes is a disease that impacts the body’s ability to respond to insulin. Insulin is a hormone made by t ...
      Written By: Zoe Michaud
      1
      OCT 03, 2022
      Technology
      Scientists Develop "RoboCap" Capsule to Deliver Drugs to Digestive Tract
      Scientists Develop "RoboCap" Capsule to Deliver Drugs to Digestive Tract
      In a recent study published in Science Robotics, a team of researchers led by the Massachusetts Institute of Technology ...
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      1
      OCT 01, 2022
      Drug Discovery & Development
      Capsule-based Fecal Microbiota Transplant Treats Clostridiodes Difficile Infection
      Capsule-based Fecal Microbiota Transplant Treats Clostridiodes Difficile Infection
      Oral treatment with Fecal Microbiota Transplant (FMT) via capsules containing freeze-dried microbes has similar effects ...
      Written By: Annie Lennon
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      SEP 30, 2022
      Technology
      Microbots Created with Algae Cells Deliver Antibiotics Directly to the Lungs
      Microbots Created with Algae Cells Deliver Antibiotics Directly to the Lungs
      Pneumonia is a common lung affliction. While a range of things can cause pneumonia, one of the most common include bacte ...
      Written By: Ryan Vingum
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      SEP 30, 2022
      Drug Discovery & Development
      A New Kind of Antiviral Against SARS-CoV-2
      A New Kind of Antiviral Against SARS-CoV-2
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      SEP 29, 2022
      Neuroscience
      Omega 3's Increase Attention, Reduce Impulsivity in Teenagers
      Omega 3's Increase Attention, Reduce Impulsivity in Teenagers
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    OCT 14, 2022
    Drug Discovery & Development
    Experimental Gene Therapy Restores Night Vision in Blind Patients
    Experimental Gene Therapy Restores Night Vision in Blind Patients
    Adults with a hereditary form of childhood-onset blindness experienced dramatic improvements in night vision within days ...
    Written By: Annie Lennon
    2
    OCT 13, 2022
    Neuroscience
    A Newly Discovered Function of the Cerebellum
    A Newly Discovered Function of the Cerebellum
    The cerebellum is primarily involved in movement, but a recent study found that the cerebellum is also involved in remem ...
    Written By: Kerry Charron
    2
    OCT 13, 2022
    Technology
    Robotic Pill Effective for Oral Delivery of Medications Like Insulin
    Robotic Pill Effective for Oral Delivery of Medications Like Insulin
    Treating and managing diabetes can be a lot of work, and it’s a condition that affects about 10% of Americans to d ...
    Written By: Ryan Vingum
    3
    OCT 13, 2022
    Cannabis Sciences
    High Doses of CBD Safe for Driving
    High Doses of CBD Safe for Driving
    The University of Sydney research team studied the effects of cannabidiol (CBD) on driving, and they found that the high ...
    Written By: Kerry Charron
    2
    OCT 12, 2022
    Cannabis Sciences
    Cannabis Use for Menopausal Symptoms
    Cannabis Use for Menopausal Symptoms
    A study published in Menopause found that women are increasingly using medical cannabis to alleviate menopause-related s ...
    Written By: Kerry Charron
    2
     
     
  • OCT 12, 2022
    Plants & Animals
    New Antimicrobial Discovered in Bacteria That Infects Potatoes
    New Antimicrobial Discovered in Bacteria That Infects Potatoes
    Resistance to antibiotics and antimicrobials has become an increasingly common concern around the globe. Due to high rat ...
    Written By: Ryan Vingum
    2
    OCT 12, 2022
    Health & Medicine
    Cavity-Causing Germs Can Form Superorganisms Able to Crawl on Teeth
    Cavity-Causing Germs Can Form Superorganisms Able to Crawl on Teeth
    Scientists have found that bacteria and fungi in the human mouth can join forces to form a superorganism that is stronge ...
    Written By: Carmen Leitch
    2
    OCT 12, 2022
    Health & Medicine
    A Coach's Authentic Leadership has a Positive Effect on Athletes
    A Coach's Authentic Leadership has a Positive Effect on Athletes
    A recent study found that the coaches who model authentic leadership influence their athletes in positive ways. The stud ...
    Written By: Kerry Charron
    2
    OCT 11, 2022
    Clinical & Molecular DX
    Researchers Discover Method of Synthesizing a Cancer Drug Discovered in the Australian Rainforest
    Researchers Discover Method of Synthesizing a Cancer Drug Discovered in the Australian Rainforest
    Tigilanol tiglate (also referred to as EBC-46) is a chemical compound with a storied history. Found naturally in the see ...
    Written By: Zoe Michaud
    2
    OCT 10, 2022
    Clinical & Molecular DX
    Scripps and Moderna Scientists Propose an HIV Vaccine Based on mRNA Technology
    Scripps and Moderna Scientists Propose an HIV Vaccine Based on mRNA Technology
    A new report published in the Journal Immunity describes an approach to developing an effective vaccine against human im ...
    Written By: Zoe Michaud
    1
     
     
  • OCT 10, 2022
    Cancer
    Experimental Drug Can Create Targets for Cancer-Killing Drugs
    Experimental Drug Can Create Targets for Cancer-Killing Drugs
    Immunotherapies continue to expand the cancer treatment landscape, providing new and exciting approaches to treat tumors ...
    Written By: Katie Kokolus
    4
    OCT 09, 2022
    Immunology
    A Gel Treatment for Gum Disease is in Development
    A Gel Treatment for Gum Disease is in Development
    Scientists have developed a gel that can relieve multiple symptoms of gum disease, and brings better health to the oral ...
    Written By: Carmen Leitch
    3
    OCT 07, 2022
    Drug Discovery & Development
    A wearable sensor that can monitor tumor size changes in real-time
    A wearable sensor that can monitor tumor size changes in real-time
    As cancer drugs are developed, one important process the drug goes through is testing in experimental animals. The use o ...
    Written By: J. Bryce Ortiz
    3
    OCT 06, 2022
    Chemistry & Physics
    2022 Nobel Prize in Chemistry
    2022 Nobel Prize in Chemistry
    It’s that time of year again! Three scientists, Carolyn R. Bertozzi, Morten Meldal, and K. Barry Sharpless, were a ...
    Written By: Hannah Daniel
    2
    OCT 05, 2022
    Technology
    Swimming Microrobots Treat Fatal Pneumonia in Mice
    Swimming Microrobots Treat Fatal Pneumonia in Mice
    In a recent study published in Nature Materials, a team of researchers from the University of California San Diego (UCSD ...
    Written By: Laurence Tognetti, MSc
    1
     
     
  • OCT 05, 2022
    Technology
    Drug Delivery System for Treating Multiple Alzheimer's Pathologies at the Same Time
    Drug Delivery System for Treating Multiple Alzheimer's Pathologies at the Same Time
    Alzheimer’s disease, which affects an estimated 5 and a half million adults in the U.S., can be caused by a number ...
    Written By: Ryan Vingum
    1
    OCT 04, 2022
    Cancer
    The NCI Welcomes First Woman Director: Monica M. Bertagnolli, MD
    The NCI Welcomes First Woman Director: Monica M. Bertagnolli, MD
    In August, President Biden announced his intention to appoint Dr. Monica M. Bertagnolli as the newest director of the Na ...
    Written By: Katie Kokolus
    5
    OCT 03, 2022
    Plants & Animals
    Yeast Proteins Could Provide Clues for New Antifungal Development
    Yeast Proteins Could Provide Clues for New Antifungal Development
    Yeast, like bacteria, causes infections. In fact, yeasts are responsible for over 100 million infections every year. The ...
    Written By: Ryan Vingum
    1
    OCT 03, 2022
    Clinical & Molecular DX
    Could Blood Samples Detect the Risk of Peripheral Neuropathy in Type 2 Diabetes?
    Could Blood Samples Detect the Risk of Peripheral Neuropathy in Type 2 Diabetes?
    Type 2 diabetes is a disease that impacts the body’s ability to respond to insulin. Insulin is a hormone made by t ...
    Written By: Zoe Michaud
    1
    OCT 03, 2022
    Technology
    Scientists Develop "RoboCap" Capsule to Deliver Drugs to Digestive Tract
    Scientists Develop "RoboCap" Capsule to Deliver Drugs to Digestive Tract
    In a recent study published in Science Robotics, a team of researchers led by the Massachusetts Institute of Technology ...
    Written By: Laurence Tognetti, MSc
    1
     
     
  • OCT 01, 2022
    Drug Discovery & Development
    Capsule-based Fecal Microbiota Transplant Treats Clostridiodes Difficile Infection
    Capsule-based Fecal Microbiota Transplant Treats Clostridiodes Difficile Infection
    Oral treatment with Fecal Microbiota Transplant (FMT) via capsules containing freeze-dried microbes has similar effects ...
    Written By: Annie Lennon
    1
    SEP 30, 2022
    Technology
    Microbots Created with Algae Cells Deliver Antibiotics Directly to the Lungs
    Microbots Created with Algae Cells Deliver Antibiotics Directly to the Lungs
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    Written By: Ryan Vingum
    1
    SEP 30, 2022
    Drug Discovery & Development
    A New Kind of Antiviral Against SARS-CoV-2
    A New Kind of Antiviral Against SARS-CoV-2
    Scientists are developing a human version of a drug that was highly beneficial to a hamster model of COVID-19. The drug, ...
    Written By: Carmen Leitch
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    SEP 29, 2022
    Neuroscience
    Omega 3's Increase Attention, Reduce Impulsivity in Teenagers
    Omega 3's Increase Attention, Reduce Impulsivity in Teenagers
    Omega-3 fatty acids from fish are linked to greater selective and sustained attention in teenagers, while omega 3’ ...
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