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    Drug Discovery

    Drug Discovery: drug discovery is the process by which new candidate medications are discovered. Historically, drugs were discovered through identifying the active ingredient from traditional remedies or by serendipitous discovery. Modern drug discovery involves the identification of screening hits, medicinal chemistry and optimization of those hits to increase the affinity, selectivity (to reduce the potential of side effects), efficacy/potency, metabolic stability (to increase the half-life), and oral bioavailability.

    Trending News

    • MAY 13, 2022
      Drug Discovery & Development
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      Opioid Addiction Treatments Minimize Fetal Brain Changes
      The rise in opioid use, addiction, and overdose is a serious public health matter. Almost 850,000 people have died of dr ...
      Written By: Ryan Vingum
      1
      MAY 13, 2022
      Drug Discovery & Development
      Multiple Mental Health Diagnoses are Increasingly Common. Why?
      Multiple Mental Health Diagnoses are Increasingly Common. Why?
      Mental illness has become increasingly common. The number of people with anxiety and depression, specifically, has stead ...
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      MAY 13, 2022
      Drug Discovery & Development
      Promising New Treatment for Cat Litter Parasite T. Gondii
      Promising New Treatment for Cat Litter Parasite T. Gondii
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      MAY 13, 2022
      Health & Medicine
      Increased Mental Health Risks Linked to High Potency Cannabis Concentrates
      Increased Mental Health Risks Linked to High Potency Cannabis Concentrates
      As more states legalize cannabis for medical and recreational purposes, the association between excessive cannabis consu ...
      Written By: Kerry Charron
      1
      MAY 12, 2022
      Drug Discovery & Development
      Gut Bacteria Composition Predicts Resposnse to Statins
      Gut Bacteria Composition Predicts Resposnse to Statins
      The composition of the gut microbiome is predictive of patient responses to statins. The corresponding study was publish ...
      Written By: Annie Lennon
      1
      MAY 11, 2022
      Drug Discovery & Development
      Gene Therapy Shows Promise for Neuropathic Pain
      Gene Therapy Shows Promise for Neuropathic Pain
      A gene therapy has been able to inhibit neuropathic pain with no detectable side effects in mice with spinal cord and pe ...
      Written By: Annie Lennon
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      MAY 11, 2022
      Cannabis Sciences
      Legal Recreational Cannabis Reduces Prescription Drug Demand
      Legal Recreational Cannabis Reduces Prescription Drug Demand
      A research study published in Health Economics found a link between the availability of legal recreational cannabis, and ...
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      MAY 10, 2022
      Immunology
      A Failed Immunotherapy Trial Leads to a Crucial Discovery
      A Failed Immunotherapy Trial Leads to a Crucial Discovery
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      MAY 09, 2022
      Cancer
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      A Gel Implant Protects from Cancer Recurrence
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      MAY 07, 2022
      Drug Discovery & Development
      Ibuprofen and Blood Pressure Medication Linked to Kidney Damage
      Ibuprofen and Blood Pressure Medication Linked to Kidney Damage
      A combination of ibuprofen and certain blood pressure medications could lead to acute kidney injury. The corresponding s ...
      Written By: Annie Lennon
      2
      MAY 06, 2022
      Drug Discovery & Development
      Scientists discover new methods of production for Sulphur-based medications
      Scientists discover new methods of production for Sulphur-based medications
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      MAY 05, 2022
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      Insulin Nasal Spray Improves Cognitive Outcome for Diabetes Patients
      Insulin Nasal Spray Improves Cognitive Outcome for Diabetes Patients
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      1
      MAY 02, 2022
      Drug Discovery & Development
      Synthetic Coating Improves Survival of Oral Medications During Digestion
      Synthetic Coating Improves Survival of Oral Medications During Digestion
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      MAY 02, 2022
      Cell & Molecular Biology
      Pipette Matchmaker: Tip Compatibility Like Never Before
      Pipette Matchmaker: Tip Compatibility Like Never Before
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      MAY 02, 2022
      Immunology
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      A Gene Defect That Causes Deadly Reactions to Viruses & Vaccines
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      3
      APR 28, 2022
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      APR 28, 2022
      Drug Discovery & Development
      Keto Molecule Shows Promise for Treating Colorectal Cancer
      Keto Molecule Shows Promise for Treating Colorectal Cancer
      A molecule produced when on low-carbohydrate ketogenic diets suppresses the growth of colorectal tumors in the lab. The ...
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      2
      APR 28, 2022
      Drug Discovery & Development
      Essential Vitamins and Minerals Help Children with ADHD and Emotional Dysregulation
      Essential Vitamins and Minerals Help Children with ADHD and Emotional Dysregulation
      Conditions like attention deficit hyperactivity disorder (ADHD) have become increasingly common. An estimated 6.1 millio ...
      Written By: Ryan Vingum
      2
      APR 28, 2022
      Genetics & Genomics
      A Genetic Cause of Lupus is Identified
      A Genetic Cause of Lupus is Identified
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      3
      APR 28, 2022
      Health & Medicine
      Antidepressants Not Associated Improved Quality of Life
      Antidepressants Not Associated Improved Quality of Life
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      Written By: Kerry Charron
      2
      APR 26, 2022
      Immunology
      Unraveling the Mystery of an Immune Cell Checkpoint
      Unraveling the Mystery of an Immune Cell Checkpoint
      The immune system can get tired when it has to fight against a chronic infection or a disease like cancer. Exhausted T c ...
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      2
      APR 25, 2022
      Microbiology
      How a Serious Infection Can Cause Mood Disorders
      How a Serious Infection Can Cause Mood Disorders
      When a pathogen invades the body, the immune system has to mount a response, which involves inflammation. But inflammati ...
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      4
      APR 25, 2022
      Health & Medicine
      Sex differences in association between cannabis use and diabetes
      Sex differences in association between cannabis use and diabetes
      A preprint published in Cannabis Cannabinoid Research examined the association between cannabis use and diabetes to dete ...
      Written By: Kerry Charron
      1
      APR 22, 2022
      Health & Medicine
      Differences in the Impact of Acute and Chronic Cannabis Use on Stress Response Regulation
      Differences in the Impact of Acute and Chronic Cannabis Use on Stress Response Regulation
      A new study published in Frontiers examined the influence of acute and chronic cannabis use on stress regulation. Althou ...
      Written By: Kerry Charron
      1
    MAY 13, 2022
    Drug Discovery & Development
    Opioid Addiction Treatments Minimize Fetal Brain Changes
    Opioid Addiction Treatments Minimize Fetal Brain Changes
    The rise in opioid use, addiction, and overdose is a serious public health matter. Almost 850,000 people have died of dr ...
    Written By: Ryan Vingum
    1
    MAY 13, 2022
    Drug Discovery & Development
    Multiple Mental Health Diagnoses are Increasingly Common. Why?
    Multiple Mental Health Diagnoses are Increasingly Common. Why?
    Mental illness has become increasingly common. The number of people with anxiety and depression, specifically, has stead ...
    Written By: Ryan Vingum
    2
    MAY 13, 2022
    Drug Discovery & Development
    Promising New Treatment for Cat Litter Parasite T. Gondii
    Promising New Treatment for Cat Litter Parasite T. Gondii
    Researchers have discovered a promising therapy for those suffering from toxoplasmosis, a disease caused by a parasite l ...
    Written By: Annie Lennon
    3
    MAY 13, 2022
    Health & Medicine
    Increased Mental Health Risks Linked to High Potency Cannabis Concentrates
    Increased Mental Health Risks Linked to High Potency Cannabis Concentrates
    As more states legalize cannabis for medical and recreational purposes, the association between excessive cannabis consu ...
    Written By: Kerry Charron
    1
    MAY 12, 2022
    Drug Discovery & Development
    Gut Bacteria Composition Predicts Resposnse to Statins
    Gut Bacteria Composition Predicts Resposnse to Statins
    The composition of the gut microbiome is predictive of patient responses to statins. The corresponding study was publish ...
    Written By: Annie Lennon
    1
     
     
  • MAY 11, 2022
    Drug Discovery & Development
    Gene Therapy Shows Promise for Neuropathic Pain
    Gene Therapy Shows Promise for Neuropathic Pain
    A gene therapy has been able to inhibit neuropathic pain with no detectable side effects in mice with spinal cord and pe ...
    Written By: Annie Lennon
    1
    MAY 11, 2022
    Cannabis Sciences
    Legal Recreational Cannabis Reduces Prescription Drug Demand
    Legal Recreational Cannabis Reduces Prescription Drug Demand
    A research study published in Health Economics found a link between the availability of legal recreational cannabis, and ...
    Written By: Kerry Charron
    1
    MAY 10, 2022
    Immunology
    A Failed Immunotherapy Trial Leads to a Crucial Discovery
    A Failed Immunotherapy Trial Leads to a Crucial Discovery
    Immunotherapies, which boost a patient's immune system so it's better at fighting cancer, have been a game-chang ...
    Written By: Carmen Leitch
    4
    MAY 09, 2022
    Cancer
    A Gel Implant Protects from Cancer Recurrence
    A Gel Implant Protects from Cancer Recurrence
    Following a successful course of cancer treatment, a patient may enter remission. Remission, classified as either partia ...
    Written By: Katie Kokolus
    5
    MAY 07, 2022
    Drug Discovery & Development
    Ibuprofen and Blood Pressure Medication Linked to Kidney Damage
    Ibuprofen and Blood Pressure Medication Linked to Kidney Damage
    A combination of ibuprofen and certain blood pressure medications could lead to acute kidney injury. The corresponding s ...
    Written By: Annie Lennon
    2
     
     
  • MAY 06, 2022
    Drug Discovery & Development
    Scientists discover new methods of production for Sulphur-based medications
    Scientists discover new methods of production for Sulphur-based medications
    Modern medicine has drastically changed since humans discovered the first ancient treatment methods. Herbal remedies and ...
    Written By: Mandy Woods
    3
    MAY 05, 2022
    Drug Discovery & Development
    Insulin Nasal Spray Improves Cognitive Outcome for Diabetes Patients
    Insulin Nasal Spray Improves Cognitive Outcome for Diabetes Patients
    Diabetes is an increasingly common condition that affects at least 1 in 10 U.S adults. Millions more have prediabetes an ...
    Written By: Ryan Vingum
    1
    MAY 02, 2022
    Drug Discovery & Development
    Synthetic Coating Improves Survival of Oral Medications During Digestion
    Synthetic Coating Improves Survival of Oral Medications During Digestion
    We’re probably all familiar with the (sometimes unpleasant) experience of swallowing pills. Whether ibuprofen for ...
    Written By: Ryan Vingum
    3
    MAY 02, 2022
    Cell & Molecular Biology
    Pipette Matchmaker: Tip Compatibility Like Never Before
    Pipette Matchmaker: Tip Compatibility Like Never Before
    Article Written by John Winsor All lab workers have to do it, shifting countless stacks of indiscernible boxes to f ...
    Sponsored By: Labcon
    3
    MAY 02, 2022
    Immunology
    A Gene Defect That Causes Deadly Reactions to Viruses & Vaccines
    A Gene Defect That Causes Deadly Reactions to Viruses & Vaccines
    For many years, researchers have stressed the need to add diverse populations to genetic studies, which have often cente ...
    Written By: Carmen Leitch
    3
     
     
  • APR 28, 2022
    Immunology
    Lipid Supplement May Reduce Inflammation in MS
    Lipid Supplement May Reduce Inflammation in MS
    Administration of an inflammation-mediating lipid has shown promise in reducing multiple sclerosis-related inflammation ...
    Written By: Annie Lennon
    2
    APR 28, 2022
    Drug Discovery & Development
    Keto Molecule Shows Promise for Treating Colorectal Cancer
    Keto Molecule Shows Promise for Treating Colorectal Cancer
    A molecule produced when on low-carbohydrate ketogenic diets suppresses the growth of colorectal tumors in the lab. The ...
    Written By: Annie Lennon
    2
    APR 28, 2022
    Drug Discovery & Development
    Essential Vitamins and Minerals Help Children with ADHD and Emotional Dysregulation
    Essential Vitamins and Minerals Help Children with ADHD and Emotional Dysregulation
    Conditions like attention deficit hyperactivity disorder (ADHD) have become increasingly common. An estimated 6.1 millio ...
    Written By: Ryan Vingum
    2
    APR 28, 2022
    Genetics & Genomics
    A Genetic Cause of Lupus is Identified
    A Genetic Cause of Lupus is Identified
    Lupus is an autoimmune disease that can impact anyone, but tends to affects women between the ages of 15 and 45. The dis ...
    Written By: Carmen Leitch
    3
    APR 28, 2022
    Health & Medicine
    Antidepressants Not Associated Improved Quality of Life
    Antidepressants Not Associated Improved Quality of Life
    According to a recently published study in PLoS, antidepressants do not improve health-related quality of life (HRQoL) o ...
    Written By: Kerry Charron
    2
     
     
  • APR 26, 2022
    Immunology
    Unraveling the Mystery of an Immune Cell Checkpoint
    Unraveling the Mystery of an Immune Cell Checkpoint
    The immune system can get tired when it has to fight against a chronic infection or a disease like cancer. Exhausted T c ...
    Written By: Carmen Leitch
    2
    APR 25, 2022
    Microbiology
    How a Serious Infection Can Cause Mood Disorders
    How a Serious Infection Can Cause Mood Disorders
    When a pathogen invades the body, the immune system has to mount a response, which involves inflammation. But inflammati ...
    Written By: Carmen Leitch
    4
    APR 25, 2022
    Health & Medicine
    Sex differences in association between cannabis use and diabetes
    Sex differences in association between cannabis use and diabetes
    A preprint published in Cannabis Cannabinoid Research examined the association between cannabis use and diabetes to dete ...
    Written By: Kerry Charron
    1
    APR 22, 2022
    Health & Medicine
    Differences in the Impact of Acute and Chronic Cannabis Use on Stress Response Regulation
    Differences in the Impact of Acute and Chronic Cannabis Use on Stress Response Regulation
    A new study published in Frontiers examined the influence of acute and chronic cannabis use on stress regulation. Althou ...
    Written By: Kerry Charron
    1
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