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    Drug Discovery

    Drug Discovery: drug discovery is the process by which new candidate medications are discovered. Historically, drugs were discovered through identifying the active ingredient from traditional remedies or by serendipitous discovery. Modern drug discovery involves the identification of screening hits, medicinal chemistry and optimization of those hits to increase the affinity, selectivity (to reduce the potential of side effects), efficacy/potency, metabolic stability (to increase the half-life), and oral bioavailability.

    Trending News

    • MAR 24, 2021
      Drug Discovery & Development
      Three Compounds May Be Suitable for SARS-CoV-2
      Three Compounds May Be Suitable for SARS-CoV-2
      Researchers have found that that three common antiviral and antimalarial therapeutics may be effective in vitro at targe ...
      Written By: Nouran Amin
      1 1
      MAR 22, 2021
      Cancer
      Can we use our own bacteria to fight cancer?
      Can we use our own bacteria to fight cancer?
      New research highlighted recently in Nature explores the ways that bacteria in tumors could be targeted to trigger immun ...
      Written By: Kathryn DeMuth Sullivan
      2
      MAR 21, 2021
      Microbiology
      Potent Drug Rapidly Clears Drug-Resistant Gonorrhea in Mouse Model
      Potent Drug Rapidly Clears Drug-Resistant Gonorrhea in Mouse Model
      A mouse model has shown that it's possible to clear a multi-drug resistant gonorrhea with only one dose of antibioti ...
      Written By: Carmen Leitch
      2
      MAR 20, 2021
      Drug Discovery & Development
      Weekly Insulin for Type 2 Diabetes Proved Effective
      Weekly Insulin for Type 2 Diabetes Proved Effective
      A study found that a new once-weekly basal insulin injection holds similar efficacy, safety and lower rate of low blood ...
      Written By: Nouran Amin
      1
      MAR 18, 2021
      Drug Discovery & Development
      New Cancer Immunotherapy Targets Genetic Alteration in All Cancers
      New Cancer Immunotherapy Targets Genetic Alteration in All Cancers
      Researchers have developed a prototype for a new kind of cancer immunotherapy. The therapy uses engineered T-cells to ta ...
      Written By: Annie Lennon
      1
      MAR 18, 2021
      Technology
      Technology Fixes Errors Associated with Self-Administering Medications
      Technology Fixes Errors Associated with Self-Administering Medications
      Almost all medications allow patients to self-administer—however, that does not mean that they always get it right ...
      Written By: Nouran Amin
      1
      MAR 16, 2021
      Drug Discovery & Development
      Machine Learning Speeds Up Drug Discovery
      Machine Learning Speeds Up Drug Discovery
      How do drugs work? Well, they work when they stick to their target protein. Of course, there is much more complicated pr ...
      Written By: Nouran Amin
      1
      MAR 12, 2021
      Drug Discovery & Development
      Drug Starves Melanoma Tumors
      Drug Starves Melanoma Tumors
      Scientists at Sanford Burnham Prebys Medical Discovery Institute have identified a drug candidate that blocks the uptake ...
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      1
      MAR 11, 2021
      Immunology
      Bye-Bye Burning: A New UTI Vaccine
      Bye-Bye Burning: A New UTI Vaccine
      Researchers have developed a vaccine that “trains” the bladder to fight back against the bacteria that cause ...
      Written By: Tara Fernandes
      3
      MAR 09, 2021
      Cannabis Sciences
      Cannabis Alleviates Neuropathic Pain from Chemotherapy
      Cannabis Alleviates Neuropathic Pain from Chemotherapy
      Neuropathic pain from oxaliplatin-based chemotherapy regimens occurs in up to 90% of patients, and continued exposure to ...
      Written By: Annie Lennon
      2
      MAR 09, 2021
      Immunology
      A 'Plug-and-Play' CRISPR Therapy for Flu and COVID
      A 'Plug-and-Play' CRISPR Therapy for Flu and COVID
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      Written By: Tara Fernandes
      4
      MAR 09, 2021
      Cannabis Sciences
      Top Benefits of Having Your Medical Marijuana Card
      Top Benefits of Having Your Medical Marijuana Card
      With the use of medicinal marijuana booming, estimated at almost 4.5 million patients in 2020, it’s time to talk a ...
      Written By: Veriheal He
      1
      MAR 09, 2021
      Drug Discovery & Development
      Leprosy Drug Repurposed for Potential COVID19 Treatment
      Leprosy Drug Repurposed for Potential COVID19 Treatment
      New research published in Nature study shows that a drug for treating leprosy was repurposed to treat COVID19. The study ...
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      1
      MAR 09, 2021
      Drug Discovery & Development
      Personalized Psychedelic Assisted-Therapy
      Personalized Psychedelic Assisted-Therapy
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      Written By: Nouran Amin
      1
      MAR 08, 2021
      Cell & Molecular Biology
      The Cause of Post-Surgical Scarring, Revealed
      The Cause of Post-Surgical Scarring, Revealed
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      1
      MAR 06, 2021
      Genetics & Genomics
      Green Tea Extract Can Affect Facial Development in Kids With Down Syndrome
      Green Tea Extract Can Affect Facial Development in Kids With Down Syndrome
      Individuals with Down syndrome often have certain facial features. New research has suggested that green tea supplements ...
      Written By: Carmen Leitch
      1
      MAR 05, 2021
      Drug Discovery & Development
      Personalized Treatment for Sickle Cell Disease
      Personalized Treatment for Sickle Cell Disease
      Globally, the most prevalent inherited blood disease is sickle cell which affects 70,000 to 100,000 Americans. Despite s ...
      Written By: Nouran Amin
      1
      MAR 04, 2021
      Drug Discovery & Development
      How Placebo Drugs for Pain Work in the Brain
      How Placebo Drugs for Pain Work in the Brain
      Researchers from Dartmouth College have found that pain relief drugs that work via the placebo effect reduce pain-relate ...
      Written By: Annie Lennon
      1
      MAR 04, 2021
      Infographics
      All You Need to Know about COVID-19 Vaccines
      All You Need to Know about COVID-19 Vaccines
      After over a year lockdowns brought on by the pandemic, hopes for returning to something even similar to ' ...
      Written By: Annie Lennon
      4 1
      MAR 03, 2021
      Drug Discovery & Development
      Keeping HIV Latent
      Keeping HIV Latent
      When (HIV) human immunodeficiency virus infects cells, it can go to sleep as opposed to make viral copies of itself&mdas ...
      Written By: Nouran Amin
      1
      MAR 02, 2021
      Health & Medicine
      Vitamin B6 May Reduce the Risk of Severe COVID-19
      Vitamin B6 May Reduce the Risk of Severe COVID-19
      Scientists are trying to learn more about whether any nutrients, like vitamins C, D, and now B6, can provide some protec ...
      Written By: Carmen Leitch
      2
      MAR 02, 2021
      Immunology
      Another Trick up Tumors' Sleeves Exposed
      Another Trick up Tumors' Sleeves Exposed
      Tumors have sneaky strategies for establishing themselves within healthy tissues, flourishing in plain sight of circulat ...
      Written By: Tara Fernandes
      2
      MAR 01, 2021
      Microbiology
      New Therapeutic Potential for a 'Miracle Poison'
      New Therapeutic Potential for a 'Miracle Poison'
      Most people know botulism as a nasty disease and botox as a wrinkle reducer that may cause a 'frozen' look if it's overu ...
      Written By: Carmen Leitch
      2
      FEB 26, 2021
      Microbiology
      Good Bacteria Fights Bad Bacteria in a Clinical Trial
      Good Bacteria Fights Bad Bacteria in a Clinical Trial
      Eczema is a skin condition that causes a chronic, itchy rash. The most common form of the disorder, atopic dermatitis, i ...
      Written By: Carmen Leitch
      1
    MAR 24, 2021
    Drug Discovery & Development
    Three Compounds May Be Suitable for SARS-CoV-2
    Three Compounds May Be Suitable for SARS-CoV-2
    Researchers have found that that three common antiviral and antimalarial therapeutics may be effective in vitro at targe ...
    Written By: Nouran Amin
    1 1
    MAR 22, 2021
    Cancer
    Can we use our own bacteria to fight cancer?
    Can we use our own bacteria to fight cancer?
    New research highlighted recently in Nature explores the ways that bacteria in tumors could be targeted to trigger immun ...
    Written By: Kathryn DeMuth Sullivan
    2
    MAR 21, 2021
    Microbiology
    Potent Drug Rapidly Clears Drug-Resistant Gonorrhea in Mouse Model
    Potent Drug Rapidly Clears Drug-Resistant Gonorrhea in Mouse Model
    A mouse model has shown that it's possible to clear a multi-drug resistant gonorrhea with only one dose of antibioti ...
    Written By: Carmen Leitch
    2
    MAR 20, 2021
    Drug Discovery & Development
    Weekly Insulin for Type 2 Diabetes Proved Effective
    Weekly Insulin for Type 2 Diabetes Proved Effective
    A study found that a new once-weekly basal insulin injection holds similar efficacy, safety and lower rate of low blood ...
    Written By: Nouran Amin
    1
    MAR 18, 2021
    Drug Discovery & Development
    New Cancer Immunotherapy Targets Genetic Alteration in All Cancers
    New Cancer Immunotherapy Targets Genetic Alteration in All Cancers
    Researchers have developed a prototype for a new kind of cancer immunotherapy. The therapy uses engineered T-cells to ta ...
    Written By: Annie Lennon
    1
     
     
  • MAR 18, 2021
    Technology
    Technology Fixes Errors Associated with Self-Administering Medications
    Technology Fixes Errors Associated with Self-Administering Medications
    Almost all medications allow patients to self-administer—however, that does not mean that they always get it right ...
    Written By: Nouran Amin
    1
    MAR 16, 2021
    Drug Discovery & Development
    Machine Learning Speeds Up Drug Discovery
    Machine Learning Speeds Up Drug Discovery
    How do drugs work? Well, they work when they stick to their target protein. Of course, there is much more complicated pr ...
    Written By: Nouran Amin
    1
    MAR 12, 2021
    Drug Discovery & Development
    Drug Starves Melanoma Tumors
    Drug Starves Melanoma Tumors
    Scientists at Sanford Burnham Prebys Medical Discovery Institute have identified a drug candidate that blocks the uptake ...
    Written By: Nouran Amin
    1
    MAR 11, 2021
    Immunology
    Bye-Bye Burning: A New UTI Vaccine
    Bye-Bye Burning: A New UTI Vaccine
    Researchers have developed a vaccine that “trains” the bladder to fight back against the bacteria that cause ...
    Written By: Tara Fernandes
    3
    MAR 09, 2021
    Cannabis Sciences
    Cannabis Alleviates Neuropathic Pain from Chemotherapy
    Cannabis Alleviates Neuropathic Pain from Chemotherapy
    Neuropathic pain from oxaliplatin-based chemotherapy regimens occurs in up to 90% of patients, and continued exposure to ...
    Written By: Annie Lennon
    2
     
     
  • MAR 09, 2021
    Immunology
    A 'Plug-and-Play' CRISPR Therapy for Flu and COVID
    A 'Plug-and-Play' CRISPR Therapy for Flu and COVID
    Researchers have developed a CRISPR treatment that could potentially treat both viruses that cause COVID-19 and influenz ...
    Written By: Tara Fernandes
    4
    MAR 09, 2021
    Cannabis Sciences
    Top Benefits of Having Your Medical Marijuana Card
    Top Benefits of Having Your Medical Marijuana Card
    With the use of medicinal marijuana booming, estimated at almost 4.5 million patients in 2020, it’s time to talk a ...
    Written By: Veriheal He
    1
    MAR 09, 2021
    Drug Discovery & Development
    Leprosy Drug Repurposed for Potential COVID19 Treatment
    Leprosy Drug Repurposed for Potential COVID19 Treatment
    New research published in Nature study shows that a drug for treating leprosy was repurposed to treat COVID19. The study ...
    Written By: Nouran Amin
    1
    MAR 09, 2021
    Drug Discovery & Development
    Personalized Psychedelic Assisted-Therapy
    Personalized Psychedelic Assisted-Therapy
    Psychedelics have long been known for their therapeutic in treating mental health disorders. However, there remains a co ...
    Written By: Nouran Amin
    1
    MAR 08, 2021
    Cell & Molecular Biology
    The Cause of Post-Surgical Scarring, Revealed
    The Cause of Post-Surgical Scarring, Revealed
    Our bodies can heal many injuries we endure, and while the process often works well, problems can also arise. After abdo ...
    Written By: Carmen Leitch
    1
     
     
  • MAR 06, 2021
    Genetics & Genomics
    Green Tea Extract Can Affect Facial Development in Kids With Down Syndrome
    Green Tea Extract Can Affect Facial Development in Kids With Down Syndrome
    Individuals with Down syndrome often have certain facial features. New research has suggested that green tea supplements ...
    Written By: Carmen Leitch
    1
    MAR 05, 2021
    Drug Discovery & Development
    Personalized Treatment for Sickle Cell Disease
    Personalized Treatment for Sickle Cell Disease
    Globally, the most prevalent inherited blood disease is sickle cell which affects 70,000 to 100,000 Americans. Despite s ...
    Written By: Nouran Amin
    1
    MAR 04, 2021
    Drug Discovery & Development
    How Placebo Drugs for Pain Work in the Brain
    How Placebo Drugs for Pain Work in the Brain
    Researchers from Dartmouth College have found that pain relief drugs that work via the placebo effect reduce pain-relate ...
    Written By: Annie Lennon
    1
    MAR 04, 2021
    Infographics
    All You Need to Know about COVID-19 Vaccines
    All You Need to Know about COVID-19 Vaccines
    After over a year lockdowns brought on by the pandemic, hopes for returning to something even similar to ' ...
    Written By: Annie Lennon
    4 1
    MAR 03, 2021
    Drug Discovery & Development
    Keeping HIV Latent
    Keeping HIV Latent
    When (HIV) human immunodeficiency virus infects cells, it can go to sleep as opposed to make viral copies of itself&mdas ...
    Written By: Nouran Amin
    1
     
     
  • MAR 02, 2021
    Health & Medicine
    Vitamin B6 May Reduce the Risk of Severe COVID-19
    Vitamin B6 May Reduce the Risk of Severe COVID-19
    Scientists are trying to learn more about whether any nutrients, like vitamins C, D, and now B6, can provide some protec ...
    Written By: Carmen Leitch
    2
    MAR 02, 2021
    Immunology
    Another Trick up Tumors' Sleeves Exposed
    Another Trick up Tumors' Sleeves Exposed
    Tumors have sneaky strategies for establishing themselves within healthy tissues, flourishing in plain sight of circulat ...
    Written By: Tara Fernandes
    2
    MAR 01, 2021
    Microbiology
    New Therapeutic Potential for a 'Miracle Poison'
    New Therapeutic Potential for a 'Miracle Poison'
    Most people know botulism as a nasty disease and botox as a wrinkle reducer that may cause a 'frozen' look if it's overu ...
    Written By: Carmen Leitch
    2
    FEB 26, 2021
    Microbiology
    Good Bacteria Fights Bad Bacteria in a Clinical Trial
    Good Bacteria Fights Bad Bacteria in a Clinical Trial
    Eczema is a skin condition that causes a chronic, itchy rash. The most common form of the disorder, atopic dermatitis, i ...
    Written By: Carmen Leitch
    1
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