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Gene mutations
Gene mutations describe a change in the DNA sequence that makes up a gene. There are many kinds of gene mutations which have been characterized by scientists. The main categories of mutations are germline mutations, which occur in the gametes (haploid male or female reproductive cells), and somatic mutations, occur in all other cell types. Chromosomal alterations are mutations that change the structure of chromosomes in a variety of ways such as deletion, duplication, insertion, translocation, or inversion of a section of the chromosome. Point mutations include a single nucleotide change within the DNA and these mutations can be classified as silent (the mutation codes for the same amino acid so the change has no effect), missense (the mutation codes for an alternative amino acid), and nonsense (the mutation codes for a premature stop codon). Frameshift mutations occur when the addition or deletion of nucleotide(s) alter the reading frame of the sequence altering all subsequent amino acid coding.
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DEC 28, 2017Cancer
Participants experienced an improvement in global sleep quality.Written By: Julia TraversDEC 23, 2017Genetics & Genomics
Researchers have shown that additions, deletions and rearrangements can alter the structure of the genome, and lead to p ...Written By: Carmen LeitchDEC 22, 2017Genetics & Genomics
Zebrafish don't seem to have a lot in common with people, but they make an excellent research model.Written By: Carmen LeitchDEC 19, 2017Genetics & Genomics
The field of personalized medicine studies how individual differences in genes impact drug efficacy.Written By: Carmen LeitchDEC 17, 2017Drug Discovery & Development
Brief overview of epigenetic therapeuticsWritten By: Courtney SchaalDEC 12, 2017Cancer
Time and time again, cancer has proven to be a most complex and formidable enemy. In many instances, cancer has outwitte ...DEC 11, 2017Genetics & Genomics
There is a genetic disorder affecting the immune system so severely that its patients often require protective isolation ...Written By: Kara MarkerDEC 10, 2017Drug Discovery & Development
AAV viral vector gene delivery will soon be approved for FDA approval, and will likely just be the first of many proving ...Written By: Courtney SchaalDEC 09, 2017Drug Discovery & Development
Pitfalls and considerations in all things factoring into identifying and targeting actionable targetsWritten By: Courtney SchaalDEC 07, 2017Genetics & Genomics
CRISPR/Cas9 gene editing technology has been hailed as revolutionary, but the technique came with some caveats. Now, it ...Written By: Carmen LeitchDEC 07, 2017Chemistry & Physics
This past Sunday marked the seventy-five anniversary of the day when the world’s first man-made self-sustainable c ...Written By: Daniel DuanDEC 05, 2017Drug Discovery & Development
Summary of ethical principles for biotechnology advances in human disease set forth by global summitWritten By: Courtney SchaalDEC 04, 2017Drug Discovery & Development
What is drug discovery and what does it entailWritten By: Courtney SchaalNOV 29, 2017Drug Discovery & Development
New evidence that chromatin rearranges in a reversible manner in drug resistant cancer cellsWritten By: Courtney SchaalNOV 25, 2017Cell & Molecular Biology
Antibiotic resistance is a growing health problem, one that already kills an estimated 23,000 people every year in the U ...Written By: Carmen LeitchNOV 24, 2017Genetics & Genomics
Children that suffer from epidermolysis bullosa, sometimes called butterfly children because of their fragile skin, face ...Written By: Carmen LeitchNOV 20, 2017Genetics & Genomics
CRISPR gene editing is being attempted for the first time in an adult; the patient has a disease called Hunter Syndrome.Written By: Carmen LeitchNOV 18, 2017Drug Discovery & Development
Scientists in Europe Use Genetically Modified Patient Stem Cells to Graft Whole Body SkinWritten By: Courtney SchaalNOV 17, 2017Cell & Molecular Biology
A new tool has been developed by Canon BioMedical that aims to improve the diagnosis and treatment of a devastating dise ...Written By: Carmen LeitchNOV 16, 2017Genetics & Genomics
Genome editing, now inspired by yeast, aims to turn a 'hacksaw to a scalpel.'Written By: Carmen LeitchNOV 13, 2017Clinical & Molecular DX
Repeat sequences are common in our DNA, and are known to cause human disorders. In particular, a triplet repeat on the X ...NOV 12, 2017Drug Discovery & Development
Repurposing already approved drugs for new therapeutic indications to expedite new drugs being used in the clinicWritten By: Courtney SchaalNOV 11, 2017Clinical & Molecular DX
A boy whose extremely fragile skin, like that of a butterfly, has been saved by an experimental therapy. The first-of-it ...NOV 10, 2017Cancer
By carefully observing how DNA is packaged inside of cancer cells, scientists have developed a therapy that they say can ...
DEC 28, 2017
Cancer
Participants experienced an improvement in global sleep quality.
Written By:
Julia Travers
DEC 23, 2017
Genetics & Genomics
Researchers have shown that additions, deletions and rearrangements can alter the structure of the genome, and lead to p
...
Written By:
Carmen Leitch
DEC 22, 2017
Genetics & Genomics
Zebrafish don't seem to have a lot in common with people, but they make an excellent research model.
Written By:
Carmen Leitch
DEC 19, 2017
Genetics & Genomics
The field of personalized medicine studies how individual differences in genes impact drug efficacy.
Written By:
Carmen Leitch
DEC 17, 2017
Drug Discovery & Development
Brief overview of epigenetic therapeutics
Written By:
Courtney Schaal
DEC 12, 2017
Cancer
Time and time again, cancer has proven to be a most complex and formidable enemy. In many instances, cancer has outwitte
...
DEC 11, 2017
Genetics & Genomics
There is a genetic disorder affecting the immune system so severely that its patients often require protective isolation
...
Written By:
Kara Marker
DEC 10, 2017
Drug Discovery & Development
AAV viral vector gene delivery will soon be approved for FDA approval, and will likely just be the first of many proving
...
Written By:
Courtney Schaal
DEC 09, 2017
Drug Discovery & Development
Pitfalls and considerations in all things factoring into identifying and targeting actionable targets
Written By:
Courtney Schaal
DEC 07, 2017
Genetics & Genomics
CRISPR/Cas9 gene editing technology has been hailed as revolutionary, but the technique came with some caveats. Now, it
...
Written By:
Carmen Leitch
DEC 07, 2017
Chemistry & Physics
This past Sunday marked the seventy-five anniversary of the day when the world’s first man-made self-sustainable c
...
Written By:
Daniel Duan
DEC 05, 2017
Drug Discovery & Development
Summary of ethical principles for biotechnology advances in human disease set forth by global summit
Written By:
Courtney Schaal
DEC 04, 2017
Drug Discovery & Development
What is drug discovery and what does it entail
Written By:
Courtney Schaal
NOV 29, 2017
Drug Discovery & Development
New evidence that chromatin rearranges in a reversible manner in drug resistant cancer cells
Written By:
Courtney Schaal
NOV 25, 2017
Cell & Molecular Biology
Antibiotic resistance is a growing health problem, one that already kills an estimated 23,000 people every year in the U
...
Written By:
Carmen Leitch
NOV 24, 2017
Genetics & Genomics
Children that suffer from epidermolysis bullosa, sometimes called butterfly children because of their fragile skin, face
...
Written By:
Carmen Leitch
NOV 20, 2017
Genetics & Genomics
CRISPR gene editing is being attempted for the first time in an adult; the patient has a disease called Hunter Syndrome.
Written By:
Carmen Leitch
NOV 18, 2017
Drug Discovery & Development
Scientists in Europe Use Genetically Modified Patient Stem Cells to Graft Whole Body Skin
Written By:
Courtney Schaal
NOV 17, 2017
Cell & Molecular Biology
A new tool has been developed by Canon BioMedical that aims to improve the diagnosis and treatment of a devastating dise
...
Written By:
Carmen Leitch
NOV 16, 2017
Genetics & Genomics
Genome editing, now inspired by yeast, aims to turn a 'hacksaw to a scalpel.'
Written By:
Carmen Leitch
NOV 13, 2017
Clinical & Molecular DX
Repeat sequences are common in our DNA, and are known to cause human disorders. In particular, a triplet repeat on the X
...
NOV 12, 2017
Drug Discovery & Development
Repurposing already approved drugs for new therapeutic indications to expedite new drugs being used in the clinic
Written By:
Courtney Schaal
NOV 11, 2017
Clinical & Molecular DX
A boy whose extremely fragile skin, like that of a butterfly, has been saved by an experimental therapy. The first-of-it
...
NOV 10, 2017
Cancer
By carefully observing how DNA is packaged inside of cancer cells, scientists have developed a therapy that they say can
...