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    Hallmarks of cancer

    The Hallmarks of Cancer comprise a summary of biological processes proposed by Douglas Hanahan and Robert Weinberg in a landmark publication in Cell in 2000. The Hallmarks acquired by cancer included 1) evading apoptosis, 2) self-sufficiency in growth signals, 3) insensitivity to anti-growth signals, 4) sustained angiogenesis, 5) tissue invasion and metastasis, and 6) limitless replicative potential. In XXX, Hanahan and Weinberg updated the hallmarks to include two emerging hallmarks (deregulating cellular energetics and avoiding immune destruction) and two enabling characteristics (genomic instability and mutation and tumor-promoting inflammation).

    Webinars

    • SEP 26, 2023 | 8:00 AM
      Exploring Extracellular Vesicles: Unlocking the Potential of EV Research
      Exploring Extracellular Vesicles: Unlocking the Potential of EV...
      Join us for an educational webinar that delves into the fascinating world of Extracellular Vesicles (EVs) and their impact on biomedical research and medicine. In collaboration with ExoVecto...
      Speaker: Roland Leathers, PhD , Jeroen de Vrij, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      41 1
      FEB 08, 2023 | 9:00 AM
      Visualizing Cancer Biology through Cell Culture Inserts
      Visualizing Cancer Biology through Cell Culture Inserts
      Date: February 08, 2023 Time: 9:00am (PST), 12:00pm (EST), 6:00pm (CEST) Understanding cell-to-cell interactions in a tumor microenvironment are increasingly challenging due to the complexit...
      Speaker: Rayees Ahamed
      Sponsored By: Thermo Fisher Scientific
      20
      SEP 27, 2022 | 10:00 AM
      Spatial Single Cell Characterization of Alzheimer's Disease in Mouse and Human Hippocampus
      Spatial Single Cell Characterization of Alzheimer's Disease in...
      Date: September 27, 2022 Time: 10:00am (PDT), 1:00pm (EDT), 7:00pm (CEST) Alzheimer’s disease is the most common cause of dementia and the seventh leading cause of death in the United...
      Speaker: Vikram Devgan , Miranda Orr
      Sponsored By: NanoString Technologies
      10
      JUN 28, 2022 | 9:00 PM
      Mastering basic techniques for cancer cell culture
      Mastering basic techniques for cancer cell culture
      Date: June 29, 2022 Time: 12:00pm (PST), 2:00pm (EST), 8:00pm (CEST) The burden of antimicrobial resistance (AMR) has been acknowledged worldwide by leading health institutes. Besides the ne...
      Speaker: Brittany Balhouse
      Sponsored By: Thermo Fisher Scientific/Gibco
      40 2
      OCT 07, 2021 | 7:30 AM
      Uncover All Hallmarks of Cancer with Multiplex Gene and Protein Assays Using Luminex Technology
      Uncover All Hallmarks of Cancer with Multiplex Gene and Protein...
      Advances in cancer research have improved our understanding of the complex interactions between tumors, their microenvironment and the host immune response. The evolving research field of im...
      Speaker: Sigrun Badrnya, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2021
      Sponsored By: Luminex - A DiaSorin Company
      2
      JUN 16, 2021 | 8:00 AM
      Simplicity that defies complexity - the MACSimaâ„¢ Platform for ultrahigh-content imaging
      Simplicity that defies complexity - the MACSimaâ„¢ Platform for...
      Date: June 16, 2021 Time: 8:00am PDT The MACSima™ Imaging Platform is the only complete solution for ultrahigh-content imaging of hundreds of markers, allowing you to understand the tu...
      Speaker: Dr. Ali Kinkhabwala , Dr. Markus Habich
      Sponsored By: Miltenyi Biotec
      7
      APR 21, 2021 | 5:00 PM
      Immunology Researchers share their Spatial Discoveries in SARS-CoV-2 host response and in multiple sclerosis
      Immunology Researchers share their Spatial Discoveries in SARS-CoV-2...
      Date: April 21, 2021 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) Spatial Answers Trilogy - Spatial Answers in Immunology Immunology Researchers share their Spatial Discoveries in SARS-C...
      Speaker: Doug Brown, PhD , Susanne Krasemann, MD, PhD , Michelle Naughton, PhD
      Sponsored By: NanoString Technologies, Illumina
      5
      SEP 17, 2020 | 12:15 PM
      Metabolic imaging of cellular heterogeneity in patient-derived cancer organoids
      Metabolic imaging of cellular heterogeneity in patient-derived...
      Abnormal cellular metabolism is a hallmark of many diseases, yet there is an absence of quantitative methods to dynamically image metabolism with cellular-level resolution. Optical metabolic...
      Speaker: Melissa C. Skala, PhD
      Presented at: 7th Annual Conference: SBI2 High Content
      1
      JUL 29, 2020 | 12:00 AM
      Therapeutic targeting of metabolic synthetic lethality in cancer research
      Therapeutic targeting of metabolic synthetic lethality in cancer...
      In this webinar, Dr. Yuting Sun discusses her research supporting a Phase 1 clinical trial advancing cancer therapies, targeted at metabolic vulnerabilities. Metabolic rewiring is a hallmark...
      Speaker: Yuting Sun, PhD
      Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
      2
      APR 21, 2020 | 1:30 PM
      Spatially Resolved Molecular Investigation of Triple Negative Breast Cancer
      Spatially Resolved Molecular Investigation of Triple Negative...
      Triple-negative breast cancer (TNBC) is an aggressive disease that accounts for 10-20% of all breast cancer cases diagnosed annually in the U.S.1. Despite its prevalence, TNBC remains resist...
      Speaker: Dina Finan, PhD , Stephen Williams, PhD
      Presented at: Genetics Week Virtual Event Series 2020
      1
      JAN 01, 2020 | 6:00 AM
      Uncovering the mechanism of stress-resistant DNA replication in cancer cells using a modern single-molecule technique
      Uncovering the mechanism of stress-resistant DNA replication in...
      Accurate DNA replication is essential to transmit the genetic information from one generation to another. However, replication is frequently challenged by barriers that originate from exogen...
      Speaker: Chames Kermi, PhD, PharmD
      Presented at: Drug Discovery & Development Virtual Event Series 2020
      1
      JUN 20, 2019 | 1:30 PM
      Single Cell CNV End-to-End Workflow to Dissect Tumor Heterogeneity
      Single Cell CNV End-to-End Workflow to Dissect Tumor Heterogeneity
      Tumor heterogeneity is a hallmark of cancer and can have significant impact on identifying drivers, including those that may be therapeutically relevant. Although, the traditional sequencing...
      Speaker: Lee Gibbs, PhD
      Presented at: Precision Medicine Virtual Event Series 2019
      1
      OCT 02, 2018 | 9:00 AM
      Comprehensive Enumeration of Immune Cells in Solid Tumors
      Comprehensive Enumeration of Immune Cells in Solid Tumors
      DATE: October 2, 2018TIME: 9:00AM PDTUnderstanding the role of distinct cellular phenotypes in tissue function, development, and pathogenesis requires tools that can rapidly and co...
      Speaker: Mike Angelo, MD. Ph.D
      Sponsored By: IONpath
      6
      SEP 20, 2018 | 8:00 AM
      Cardiovascular Disease: Applying MRI to study atherosclerosis, the aortic arch and endothelial permeability in small animal models
      Cardiovascular Disease: Applying MRI to study atherosclerosis,...
       DATE: September 20 2018TIME: 11:00am EDT, 5:00pm CEST Cardiovascular disease due to atherosclerosis is the leading cause of disease and mortality worldwide. So-call...
      Speaker: Claudia Calcagno Mani, MD, PhD
      Sponsored By: Bruker Microbiology & Diagnostics
      10
      SEP 20, 2018 | 1:00 AM
      Cardiovascular Disease: Applying MRI to study atherosclerosis, the aortic arch and endothelial permeability in small animal models
      Cardiovascular Disease: Applying MRI to study atherosclerosis,...
      DATE: September 20, 2018TIME: 10:00am CEST, 4:00pm CST Cardiovascular disease due to atherosclerosis is the leading cause of disease and mortality worldwide. So-called “...
      Speaker: Claudia Calcagno Mani, MD, PhD
      Sponsored By: Bruker Microbiology & Diagnostics
      6 1
      APR 26, 2018 | 8:00 AM
      Pre-clinical T cell immunotherapy strategies for overcoming immunosuppression in solid tumors
      Pre-clinical T cell immunotherapy strategies for overcoming immunosuppression...
      DATE:  April 26, 2018TIME:  8:00am PST, 11:00am EST Engineered T cells expressing a tumor antigen-specific receptor have revolutionized the field of cancer therap...
      Speaker: Kristin Anderson, PhD
      Sponsored By: Thermo Fisher Scientific - Applied Biosystems
      5
      APR 12, 2018 | 10:30 AM
      The Genome in 3D: A Clinical Biomarker Platform
      The Genome in 3D: A Clinical Biomarker Platform
      In genomics, as in life, you need to be in the right place at the right time, and you need integrity, to be credible. Since the availability of the human genome sequence, there's been an...
      Speaker: Kevin Little, PhD
      Presented at: Molecular Diagnostics Virtual Event Series 2018
      1
      NOV 12, 2014 | 8:00 AM
      Hallmarks of cancer - Detect and quantify cell death signatures with high content imaging
      Hallmarks of cancer - Detect and quantify cell death signatures...
      Dr. Oliver Kepp will be presenting on:Immunogenic cell death fingerprinting utilizing a high-throughput screening approachThe strategy of immunogenic cell death fingerprinting has been design...
      Speaker: Oliver Kepp, PhD and Jayne A. Hesley
      Sponsored By: Molecular Devices, Molecular Devices
      33
      OCT 29, 2014 | 1:30 PM
      Metabolic therapy for the adjuvant treatment of malignant brain tumors
      Metabolic therapy for the adjuvant treatment of malignant brain...
      Human malignant glioma is a uniformly fatal disease, causing over 14,000 deaths in the US this year. Adults diagnosed with malignant brain tumors have a median survival of approximately 15 mo...
      Speaker: Adrienne C. Scheck, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      6
      AUG 20, 2014 | 8:00 AM
      High-resolution genomic analysis reveals genetic impacts of human papillomavirus in human cancers
      High-resolution genomic analysis reveals genetic impacts of human...
      One of the hallmarks of human cancers is genetic instability. My colleagues and I recently identified a remarkable association between human papillomavirus (HPV) and genomic structural variat...
      Speaker: David E Symer, MD, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2014
      4
    SEP 26, 2023 | 8:00 AM
    Exploring Extracellular Vesicles: Unlocking the Potential of EV Research
    Exploring Extracellular Vesicles: Unlocking the Potential of EV...
    Join us for an educational webinar that delves into the fascinating world of Extracellular Vesicles (EVs) and their impact on biomedical research and medicine. In collaboration with ExoVecto...
    Speaker: Roland Leathers, PhD , Jeroen de Vrij, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    41 1
    FEB 08, 2023 | 9:00 AM
    Visualizing Cancer Biology through Cell Culture Inserts
    Visualizing Cancer Biology through Cell Culture Inserts
    Date: February 08, 2023 Time: 9:00am (PST), 12:00pm (EST), 6:00pm (CEST) Understanding cell-to-cell interactions in a tumor microenvironment are increasingly challenging due to the complexit...
    Speaker: Rayees Ahamed
    Sponsored By: Thermo Fisher Scientific
    20
    SEP 27, 2022 | 10:00 AM
    Spatial Single Cell Characterization of Alzheimer's Disease in Mouse and Human Hippocampus
    Spatial Single Cell Characterization of Alzheimer's Disease in...
    Date: September 27, 2022 Time: 10:00am (PDT), 1:00pm (EDT), 7:00pm (CEST) Alzheimer’s disease is the most common cause of dementia and the seventh leading cause of death in the United...
    Speaker: Vikram Devgan , Miranda Orr
    Sponsored By: NanoString Technologies
    10
    JUN 28, 2022 | 9:00 PM
    Mastering basic techniques for cancer cell culture
    Mastering basic techniques for cancer cell culture
    Date: June 29, 2022 Time: 12:00pm (PST), 2:00pm (EST), 8:00pm (CEST) The burden of antimicrobial resistance (AMR) has been acknowledged worldwide by leading health institutes. Besides the ne...
    Speaker: Brittany Balhouse
    Sponsored By: Thermo Fisher Scientific/Gibco
    40 2
    OCT 07, 2021 | 7:30 AM
    Uncover All Hallmarks of Cancer with Multiplex Gene and Protein Assays Using Luminex Technology
    Uncover All Hallmarks of Cancer with Multiplex Gene and Protein...
    Advances in cancer research have improved our understanding of the complex interactions between tumors, their microenvironment and the host immune response. The evolving research field of im...
    Speaker: Sigrun Badrnya, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2021
    Sponsored By: Luminex - A DiaSorin Company
    2
     
     
  • JUN 16, 2021 | 8:00 AM
    Simplicity that defies complexity - the MACSimaâ„¢ Platform for ultrahigh-content imaging
    Simplicity that defies complexity - the MACSimaâ„¢ Platform for...
    Date: June 16, 2021 Time: 8:00am PDT The MACSima™ Imaging Platform is the only complete solution for ultrahigh-content imaging of hundreds of markers, allowing you to understand the tu...
    Speaker: Dr. Ali Kinkhabwala , Dr. Markus Habich
    Sponsored By: Miltenyi Biotec
    7
    APR 21, 2021 | 5:00 PM
    Immunology Researchers share their Spatial Discoveries in SARS-CoV-2 host response and in multiple sclerosis
    Immunology Researchers share their Spatial Discoveries in SARS-CoV-2...
    Date: April 21, 2021 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) Spatial Answers Trilogy - Spatial Answers in Immunology Immunology Researchers share their Spatial Discoveries in SARS-C...
    Speaker: Doug Brown, PhD , Susanne Krasemann, MD, PhD , Michelle Naughton, PhD
    Sponsored By: NanoString Technologies, Illumina
    5
    SEP 17, 2020 | 12:15 PM
    Metabolic imaging of cellular heterogeneity in patient-derived cancer organoids
    Metabolic imaging of cellular heterogeneity in patient-derived...
    Abnormal cellular metabolism is a hallmark of many diseases, yet there is an absence of quantitative methods to dynamically image metabolism with cellular-level resolution. Optical metabolic...
    Speaker: Melissa C. Skala, PhD
    Presented at: 7th Annual Conference: SBI2 High Content
    1
    JUL 29, 2020 | 12:00 AM
    Therapeutic targeting of metabolic synthetic lethality in cancer research
    Therapeutic targeting of metabolic synthetic lethality in cancer...
    In this webinar, Dr. Yuting Sun discusses her research supporting a Phase 1 clinical trial advancing cancer therapies, targeted at metabolic vulnerabilities. Metabolic rewiring is a hallmark...
    Speaker: Yuting Sun, PhD
    Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
    2
    APR 21, 2020 | 1:30 PM
    Spatially Resolved Molecular Investigation of Triple Negative Breast Cancer
    Spatially Resolved Molecular Investigation of Triple Negative...
    Triple-negative breast cancer (TNBC) is an aggressive disease that accounts for 10-20% of all breast cancer cases diagnosed annually in the U.S.1. Despite its prevalence, TNBC remains resist...
    Speaker: Dina Finan, PhD , Stephen Williams, PhD
    Presented at: Genetics Week Virtual Event Series 2020
    1
     
     
  • JAN 01, 2020 | 6:00 AM
    Uncovering the mechanism of stress-resistant DNA replication in cancer cells using a modern single-molecule technique
    Uncovering the mechanism of stress-resistant DNA replication in...
    Accurate DNA replication is essential to transmit the genetic information from one generation to another. However, replication is frequently challenged by barriers that originate from exogen...
    Speaker: Chames Kermi, PhD, PharmD
    Presented at: Drug Discovery & Development Virtual Event Series 2020
    1
    JUN 20, 2019 | 1:30 PM
    Single Cell CNV End-to-End Workflow to Dissect Tumor Heterogeneity
    Single Cell CNV End-to-End Workflow to Dissect Tumor Heterogeneity
    Tumor heterogeneity is a hallmark of cancer and can have significant impact on identifying drivers, including those that may be therapeutically relevant. Although, the traditional sequencing...
    Speaker: Lee Gibbs, PhD
    Presented at: Precision Medicine Virtual Event Series 2019
    1
    OCT 02, 2018 | 9:00 AM
    Comprehensive Enumeration of Immune Cells in Solid Tumors
    Comprehensive Enumeration of Immune Cells in Solid Tumors
    DATE: October 2, 2018TIME: 9:00AM PDTUnderstanding the role of distinct cellular phenotypes in tissue function, development, and pathogenesis requires tools that can rapidly and co...
    Speaker: Mike Angelo, MD. Ph.D
    Sponsored By: IONpath
    6
    SEP 20, 2018 | 8:00 AM
    Cardiovascular Disease: Applying MRI to study atherosclerosis, the aortic arch and endothelial permeability in small animal models
    Cardiovascular Disease: Applying MRI to study atherosclerosis,...
     DATE: September 20 2018TIME: 11:00am EDT, 5:00pm CEST Cardiovascular disease due to atherosclerosis is the leading cause of disease and mortality worldwide. So-call...
    Speaker: Claudia Calcagno Mani, MD, PhD
    Sponsored By: Bruker Microbiology & Diagnostics
    10
    SEP 20, 2018 | 1:00 AM
    Cardiovascular Disease: Applying MRI to study atherosclerosis, the aortic arch and endothelial permeability in small animal models
    Cardiovascular Disease: Applying MRI to study atherosclerosis,...
    DATE: September 20, 2018TIME: 10:00am CEST, 4:00pm CST Cardiovascular disease due to atherosclerosis is the leading cause of disease and mortality worldwide. So-called “...
    Speaker: Claudia Calcagno Mani, MD, PhD
    Sponsored By: Bruker Microbiology & Diagnostics
    6 1
     
     
  • APR 26, 2018 | 8:00 AM
    Pre-clinical T cell immunotherapy strategies for overcoming immunosuppression in solid tumors
    Pre-clinical T cell immunotherapy strategies for overcoming immunosuppression...
    DATE:  April 26, 2018TIME:  8:00am PST, 11:00am EST Engineered T cells expressing a tumor antigen-specific receptor have revolutionized the field of cancer therap...
    Speaker: Kristin Anderson, PhD
    Sponsored By: Thermo Fisher Scientific - Applied Biosystems
    5
    APR 12, 2018 | 10:30 AM
    The Genome in 3D: A Clinical Biomarker Platform
    The Genome in 3D: A Clinical Biomarker Platform
    In genomics, as in life, you need to be in the right place at the right time, and you need integrity, to be credible. Since the availability of the human genome sequence, there's been an...
    Speaker: Kevin Little, PhD
    Presented at: Molecular Diagnostics Virtual Event Series 2018
    1
    NOV 12, 2014 | 8:00 AM
    Hallmarks of cancer - Detect and quantify cell death signatures with high content imaging
    Hallmarks of cancer - Detect and quantify cell death signatures...
    Dr. Oliver Kepp will be presenting on:Immunogenic cell death fingerprinting utilizing a high-throughput screening approachThe strategy of immunogenic cell death fingerprinting has been design...
    Speaker: Oliver Kepp, PhD and Jayne A. Hesley
    Sponsored By: Molecular Devices, Molecular Devices
    33
    OCT 29, 2014 | 1:30 PM
    Metabolic therapy for the adjuvant treatment of malignant brain tumors
    Metabolic therapy for the adjuvant treatment of malignant brain...
    Human malignant glioma is a uniformly fatal disease, causing over 14,000 deaths in the US this year. Adults diagnosed with malignant brain tumors have a median survival of approximately 15 mo...
    Speaker: Adrienne C. Scheck, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    6
    AUG 20, 2014 | 8:00 AM
    High-resolution genomic analysis reveals genetic impacts of human papillomavirus in human cancers
    High-resolution genomic analysis reveals genetic impacts of human...
    One of the hallmarks of human cancers is genetic instability. My colleagues and I recently identified a remarkable association between human papillomavirus (HPV) and genomic structural variat...
    Speaker: David E Symer, MD, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2014
    4
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