In Vitro: refers to a medical test or experiment/procedure that is conducted in a laboratory within the confines of a test tube or laboratory dish. This is not to be confused with the term in vivo, which is a medical test or procedure that is performed on or in a living organism. 
            
            
            
         
     
    
        
                    
                                    
                
         
                
                    
                                        
                        
                    
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        Perineural invasion (PNI) is a well-established factor of poor prognosis in multiple cancer types, yet its mechanism remains unclear. By using a multi-omics approach, overlay of multiple spa...
     
 
 
                                        
    
    
    
        Engineered immune cell therapies offer the promise of more tailored interventions than traditional systemic checkpoint blockades, but so far remain ineffective across the majority of clinica...
     
 
 
                                    
                                                                    
                                    
                                        
    
            
    
    
    
        Standard bioassays often fall short when evaluating T cell engagers due to their diverse mechanisms of actions (MOAs) and functional complexity. To generate meaningful preclinical data, cont...
    
    
            
     
                                     
                                    
                                                                    
                                    
                                        
    
    
    
        Double-stranded RNA (dsRNA) is a well-recognized byproduct of in vitro transcription that poses significant challenges for the use of synthetic mRNA in research and therapeutic applications....
    
    
            
     
                                     
                                    
                                                                    
                                    
                                        
    
            
    
    
    
        The release of a recent EMA reflection paper, aligning with FDA and WHO positions, has resulted in a renewed focus on the central role of pharmacokinetic (PK) data, the primary status of ana...
    
    
            
     
                                     
                                    
                                                                    
                                    
                                        
    
                    
                                    SEP 17, 2025 | 11:15 AM
                            
        
                    
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        Traditional animal models and simplified cell cultures often fail to capture human biology, limiting progress in biomedical research and drug development. Emerging microfluidic "Organ-o...
    
    
            
     
                                     
                                    
                                                                    
                                    
                                        
    
                    
                                    AUG 12, 2025 | 7:00 AM
                            
        
                    
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        Increasing the complexity of in vitro cell cultures to better model the in vivo environment is a growing focus in drug discovery and mechanistic research. It is well established that cells c...
    
    
            
     
                                     
                                    
                                                                    
                                    
                                        
    
            
    
    
    
        Due to its high accuracy and fast, simple workflow, Capillary Electrophoresis (CE) is a foundational technology for clinical applications. CE is an invaluable tool used to detect genetic var...
    
    
            
     
                                     
                                    
                                                                    
                                    
                                        
    
            
    
    
    
        The HIV-1 Nef accessory factor promotes viral replication and immune escape of HIV-infected cells, making it an attractive drug target. Our team previously identified small molecules that bi...
    
    
            
     
                                     
                                    
                                                                    
                                    
                                        
    
            
    
    
    
        The MAF bZIP Transcription Factor G (MAFG) is a member of the small MAF family of proteins. Previously, we have shown that miRNA-29 suppresses melanoma development, at least in part, by repr...
    
    
            
     
                                     
                                    
                                                                    
                                    
                                        
    
            
    
    
    
        When formulating mRNA into lipid nanoparticles (LNP), various copy numbers of mRNA are encapsulated, leading to a distribution of mRNA loading levels within the LNPs. It is unclear whether t...
    
    
            
     
                                     
                                    
                                                                    
                                    
                                        
    
                    
                                    APR 03, 2025 | 8:00 AM
                            
        
                    
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        The FDA’s landmark final rule on Laboratory Developed Tests (LDTs) is set to transform the regulatory landscape for diagnostic laboratories. This webinar will provide biomedical diagno...
    
    
            
     
                                     
                                    
                                                                    
                                    
                                        
    
            
    
    
    
        At Thermo Fisher Scientific, our goal is to bring innovative new products and services that enable the development of more physiologically relevant disease models to help accelerate the drug...
    
    
            
     
                                     
                                    
                                                                    
                                    
                                        
    
            
    
    
    
        Brain tumors are the leading cause of solid-tumor-related deaths among children. These tumors are now categorized by WHO as separated from adult brain tumors and based on their distinct mole...
    
    
            
     
                                     
                                    
                                                                    
                                    
                                        
    
                    
                                    OCT 16, 2024 | 9:00 AM
                            
        
                    
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        In today’s diagnostic test development landscape, the path to commercialization and generating topline revenue is marked by peaks and valleys. One of the first hurdles is navigating th...