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    In Vitro

    In Vitro: refers to a medical test or experiment/procedure that is conducted in a laboratory within the confines of a test tube or laboratory dish. This is not to be confused with the term in vivo, which is a medical test or procedure that is performed on or in a living organism.

    Webinars

    • NOV 18, 2025 | 10:00 AM
      Spatial mapping of immunotherapy-refractory tumors provides insights into cancer-induced nerve injury as a novel mechanism of immunotherapy resistance
      Spatial mapping of immunotherapy-refractory tumors provides insights...
      Perineural invasion (PNI) is a well-established factor of poor prognosis in multiple cancer types, yet its mechanism remains unclear. By using a multi-omics approach, overlay of multiple spa...
      Speaker: Erez Baruch
      Sponsored By: Lunaphore
      2
      OCT 22, 2025 | 12:00 PM
      Comprehensive genetic manipulation of cellular therapies
      Comprehensive genetic manipulation of cellular therapies
      Engineered immune cell therapies offer the promise of more tailored interventions than traditional systemic checkpoint blockades, but so far remain ineffective across the majority of clinica...
      Speaker: Theodore Roth, MD, PhD
      Presented at: CRISPR Virtual Event Series 2025
      Sponsored By: LONZA
      2
      OCT 16, 2025 | 3:00 PM
      [Webinar] In Vitro Assays for T Cell Engagers: From Bench to Data-Driven Decisions
      [Webinar] In Vitro Assays for T Cell Engagers: From Bench to Data-Driven...
      Standard bioassays often fall short when evaluating T cell engagers due to their diverse mechanisms of actions (MOAs) and functional complexity. To generate meaningful preclinical data, cont...
      Speaker: Rachel Wang
      Sponsored By: WuXi Biologics CRO Services
      4
      OCT 15, 2025 | 12:00 PM
      Optimizing dsRNA Removal in IVT mRNA: Strategies for Enhanced Translation and Reduced Immunogenicity
      Optimizing dsRNA Removal in IVT mRNA: Strategies for Enhanced...
      Double-stranded RNA (dsRNA) is a well-recognized byproduct of in vitro transcription that poses significant challenges for the use of synthetic mRNA in research and therapeutic applications....
      Speaker: Johnathan Parker, BS
      Presented at: Cell & Gene Therapy Virtual Event Series 2025
      Sponsored By: CELLSCRIPTâ„¢
      2
      SEP 24, 2025 | 8:00 AM
      Complex primary cell assays: strategic tools for biosimilar comparability
      Complex primary cell assays: strategic tools for biosimilar comparability
      The release of a recent EMA reflection paper, aligning with FDA and WHO positions, has resulted in a renewed focus on the central role of pharmacokinetic (PK) data, the primary status of ana...
      Speaker: Fiona Miller, BSc (Hons) Immunology and Pharmacology from the University of Strathclyde
      Sponsored By: RoukenBio
      15
      SEP 17, 2025 | 11:15 AM
      C.E. CREDITS
      Human Organ Chips: Next-Generation In Vitro Models to Advance Human Health
      Human Organ Chips: Next-Generation In Vitro Models to Advance...
      Traditional animal models and simplified cell cultures often fail to capture human biology, limiting progress in biomedical research and drug development. Emerging microfluidic "Organ-o...
      Speaker: Zohreh Izadifar, PhD
      Presented at: Cell Biology Virtual Event Series 2025
      5
      AUG 12, 2025 | 7:00 AM
      C.E. CREDITS
      3D Co-Cultures: Choosing the Best Systems & Analysis for Immuno-Oncology
      3D Co-Cultures: Choosing the Best Systems & Analysis for Immuno-Oncology
      Increasing the complexity of in vitro cell cultures to better model the in vivo environment is a growing focus in drug discovery and mechanistic research. It is well established that cells c...
      Speaker: Darryl Turner
      Sponsored By: Thermo Fisher Scientific
      20
      JUL 10, 2025 | 8:00 AM
      Clinical applications of Sanger sequencing and fragment analysis via capillary electrophoresis and an introduction to the SeqStudio Flex Dx Genetic Analyzer
      Clinical applications of Sanger sequencing and fragment analysis...
      Due to its high accuracy and fast, simple workflow, Capillary Electrophoresis (CE) is a foundational technology for clinical applications. CE is an invaluable tool used to detect genetic var...
      Speaker: Andy McNamara , Ramona Polster
      Sponsored By: Thermo Fisher Scientific
      13
      MAY 08, 2025 | 8:00 AM
      Applications of Surface Plasmon Resonance (SPR) in HIV-1 Nef Inhibitor Discovery and PROTAC Development
      Applications of Surface Plasmon Resonance (SPR) in HIV-1 Nef Inhibitor...
      The HIV-1 Nef accessory factor promotes viral replication and immune escape of HIV-infected cells, making it an attractive drug target. Our team previously identified small molecules that bi...
      Speaker: Thomas Smithgall, Ph.D.
      Sponsored By: Ametek
      10
      APR 30, 2025 | 8:00 AM
      MAFG: A key regulator in melanoma progression and a potential therapeutic target
      MAFG: A key regulator in melanoma progression and a potential...
      The MAF bZIP Transcription Factor G (MAFG) is a member of the small MAF family of proteins. Previously, we have shown that miRNA-29 suppresses melanoma development, at least in part, by repr...
      Speaker: Olga Puente, PhD
      Sponsored By: Thermo Fisher Scientific
      14 2
      APR 08, 2025 | 8:00 AM
      Transfection Potency of Lipid Nanoparticles Containing mRNA Depends on Relative Loading Levels
      Transfection Potency of Lipid Nanoparticles Containing mRNA Depends...
      When formulating mRNA into lipid nanoparticles (LNP), various copy numbers of mRNA are encapsulated, leading to a distribution of mRNA loading levels within the LNPs. It is unclear whether t...
      Speaker: Dr. Suiyang Liao
      Sponsored By: Beckman Coulter Life Sciences
      13 1
      APR 03, 2025 | 8:00 AM
      C.E. CREDITS
      Best Practices for Clinical Labs in Turbulent Times
      Best Practices for Clinical Labs in Turbulent Times
      The FDA’s landmark final rule on Laboratory Developed Tests (LDTs) is set to transform the regulatory landscape for diagnostic laboratories. This webinar will provide biomedical diagno...
      Speaker: Michael J. Donovan, Ph.D., JD , Travis Schlappi, PhD , Mara G. Aspinall, MBA
      Sponsored By: Thermo Fisher Scientific
      36
      DEC 10, 2024 | 9:00 AM
      Advances in iPSC Workflows to Build Better Models and Therapies
      Advances in iPSC Workflows to Build Better Models and Therapies
      At Thermo Fisher Scientific, our goal is to bring innovative new products and services that enable the development of more physiologically relevant disease models to help accelerate the drug...
      Speaker: Omar Farah, Ph.D.
      Sponsored By: Thermo Fisher Scientific
      15
      NOV 13, 2024 | 10:00 AM
      Single Cell Multiomic characterization of pediatric gliomas uncover novel, subtype-specific therapeutic approaches
      Single Cell Multiomic characterization of pediatric gliomas uncover...
      Brain tumors are the leading cause of solid-tumor-related deaths among children. These tumors are now categorized by WHO as separated from adult brain tumors and based on their distinct mole...
      Speaker: David Rincón Fernández Pacheco, PhD
      Sponsored By: Scale Biosciences
      8
      OCT 16, 2024 | 9:00 AM
      C.E. CREDITS
      Keynote Presentation: The Trials & Tribulations of the Clinical Diagnostic Landscape with Live Q&A
      Keynote Presentation: The Trials & Tribulations of the Clinical...
      In today’s diagnostic test development landscape, the path to commercialization and generating topline revenue is marked by peaks and valleys. One of the first hurdles is navigating th...
      Speaker: Lesley E. Northrop, PhD, FACMG
      Presented at: Cell & Gene Therapy Virtual Event Series 2024
      6
      On Demand
      C.E. CREDITS
      In Vivo Correction of Human Phenylketonuria Variants via Prime Editing and Base Editing: A Gateway to Equitable Treatment of Inborn Errors of Metabolism
      In Vivo Correction of Human Phenylketonuria Variants via Prime...
      Inborn errors of metabolism (IEMs) are rare, devastating disorders caused by pathogenic variants in genes encoding key metabolic enzymes, with the liver playing a critical role in over 140 I...
      Speaker: Xiao Wang, PhD
      Presented at: Cell & Gene Therapy Virtual Event Series 2024
      6
      On Demand
      C.E. CREDITS
      Hypertonic Saline Remarkably Enhances Gene Transfer to Airway Epithelial Cells
      Hypertonic Saline Remarkably Enhances Gene Transfer to Airway...
      A fundamental challenge for cystic fibrosis (CF) gene therapy is ensuring sufficient transduction of airway epithelial cells to achieve therapeutic correction. Vehicles such as lysophosphati...
      Speaker: Ashley Cooney, PhD
      Presented at: Cell & Gene Therapy Virtual Event Series 2024
      5 1
      OCT 02, 2024 | 11:00 AM
      Exploring myeloid cell heterogeneity in autoimmune skin diseases with novel multiomics insights
      Exploring myeloid cell heterogeneity in autoimmune skin diseases...
      Inflammatory skin disorders comprise a diverse set of conditions exhibiting unique characteristics. Our objective was to systematically compare the affected and unaffected skin of individual...
      Speaker: Khashayar Afshari, MD, MPH
      Sponsored By: Olink Proteomics
      11
      On Demand
      C.E. CREDITS
      Next Generation Genetic Discovery Systems in Human Immune Cells
      Next Generation Genetic Discovery Systems in Human Immune Cells
      Engineered immune cell therapies offer the promise of more tailored interventions than traditional systemic checkpoint blockades, but so far remain ineffective across the majority of clinica...
      Speaker: Theodore Roth, MD, PhD
      Presented at: Cancer Research & Oncology Virtual Event Series 2024
      2
      SEP 18, 2024 | 9:00 AM
      C.E. CREDITS
      Keynote Presentation: Applications of Cellular Assays for Understanding Drug Disposition of Protein Therapeutics with Live Q&A
      Keynote Presentation: Applications of Cellular Assays for Understanding...
      The disposition of antibody-based therapeutics is generally determined by both target-mediated and non-target processes, the latter being an often-overlooked aspect. Target-independent liabi...
      Speaker: Mark Bryniarski, PhD, MS
      Presented at: Cell Biology Virtual Event Series 2024
      3
      On Demand
      C.E. CREDITS
      Microphysiological Systems Research: Applications in  Biopharmaceutics and Advancements in Image Analysis
      Microphysiological Systems Research: Applications in Biopharmaceutics...
      A microphysiological system is a 3D in vitro model that mimics human tissue environments with high physiological relevance. This approach enhances our understanding of disease mechanisms, dr...
      Speaker: Eunkyung (Clare) Ko, PhD , Devin Wakefield
      Presented at: Cell Biology Virtual Event Series 2024
      4
      On Demand
      C.E. CREDITS
      Human-On-a-Chip Systems For Use in Therapeutic Index Determination and Systemic Toxicity in Pre-Clinical Drug Discovery Applications
      Human-On-a-Chip Systems For Use in Therapeutic Index Determination...
      One of the primary limitations in drug discovery and toxicology research is the lack of good model systems between the single cell level and animal or human systems. This is especially true...
      Speaker: James J. Hickman, PhD
      Presented at: Cell Biology Virtual Event Series 2024
      3
      AUG 29, 2024 | 7:00 AM
      Unleashing the Potential of mRNA Synthesis: A Deep Dive into Solid-phase In vitro Transcription
      Unleashing the Potential of mRNA Synthesis: A Deep Dive into Solid-phase...
      Unlocking the potential of mRNA technology is revolutionizing medicine and biotechnology. Solid-phase in vitro transcription enables scalability and automation, making it a valuable tool for...
      Speaker: Iwona Grad, Ph.D
      Sponsored By: Thermo Fisher Scientific
      18
      JUN 27, 2024 | 7:00 AM
      Trace-level cytokines and cardiovascular profiling for long-term COVID diagnostic
      Trace-level cytokines and cardiovascular profiling for long-term...
      Globally, over 65 million individuals are estimated to suffer from post-acute sequelae of COVID-19 (PASC). A large number of individuals living with PASC experience cardiovascular symptoms (...
      Speaker: Kirsty Short , Sonja Stoelzle-Feix
      Sponsored By: Nanion Technologies
      13
    NOV 18, 2025 | 10:00 AM
    Spatial mapping of immunotherapy-refractory tumors provides insights into cancer-induced nerve injury as a novel mechanism of immunotherapy resistance
    Spatial mapping of immunotherapy-refractory tumors provides insights...
    Perineural invasion (PNI) is a well-established factor of poor prognosis in multiple cancer types, yet its mechanism remains unclear. By using a multi-omics approach, overlay of multiple spa...
    Speaker: Erez Baruch
    Sponsored By: Lunaphore
    2
    OCT 22, 2025 | 12:00 PM
    Comprehensive genetic manipulation of cellular therapies
    Comprehensive genetic manipulation of cellular therapies
    Engineered immune cell therapies offer the promise of more tailored interventions than traditional systemic checkpoint blockades, but so far remain ineffective across the majority of clinica...
    Speaker: Theodore Roth, MD, PhD
    Presented at: CRISPR Virtual Event Series 2025
    Sponsored By: LONZA
    2
    OCT 16, 2025 | 3:00 PM
    [Webinar] In Vitro Assays for T Cell Engagers: From Bench to Data-Driven Decisions
    [Webinar] In Vitro Assays for T Cell Engagers: From Bench to Data-Driven...
    Standard bioassays often fall short when evaluating T cell engagers due to their diverse mechanisms of actions (MOAs) and functional complexity. To generate meaningful preclinical data, cont...
    Speaker: Rachel Wang
    Sponsored By: WuXi Biologics CRO Services
    4
    OCT 15, 2025 | 12:00 PM
    Optimizing dsRNA Removal in IVT mRNA: Strategies for Enhanced Translation and Reduced Immunogenicity
    Optimizing dsRNA Removal in IVT mRNA: Strategies for Enhanced...
    Double-stranded RNA (dsRNA) is a well-recognized byproduct of in vitro transcription that poses significant challenges for the use of synthetic mRNA in research and therapeutic applications....
    Speaker: Johnathan Parker, BS
    Presented at: Cell & Gene Therapy Virtual Event Series 2025
    Sponsored By: CELLSCRIPTâ„¢
    2
    SEP 24, 2025 | 8:00 AM
    Complex primary cell assays: strategic tools for biosimilar comparability
    Complex primary cell assays: strategic tools for biosimilar comparability
    The release of a recent EMA reflection paper, aligning with FDA and WHO positions, has resulted in a renewed focus on the central role of pharmacokinetic (PK) data, the primary status of ana...
    Speaker: Fiona Miller, BSc (Hons) Immunology and Pharmacology from the University of Strathclyde
    Sponsored By: RoukenBio
    15
     
     
  • SEP 17, 2025 | 11:15 AM
    C.E. CREDITS
    Human Organ Chips: Next-Generation In Vitro Models to Advance Human Health
    Human Organ Chips: Next-Generation In Vitro Models to Advance...
    Traditional animal models and simplified cell cultures often fail to capture human biology, limiting progress in biomedical research and drug development. Emerging microfluidic "Organ-o...
    Speaker: Zohreh Izadifar, PhD
    Presented at: Cell Biology Virtual Event Series 2025
    5
    AUG 12, 2025 | 7:00 AM
    C.E. CREDITS
    3D Co-Cultures: Choosing the Best Systems & Analysis for Immuno-Oncology
    3D Co-Cultures: Choosing the Best Systems & Analysis for Immuno-Oncology
    Increasing the complexity of in vitro cell cultures to better model the in vivo environment is a growing focus in drug discovery and mechanistic research. It is well established that cells c...
    Speaker: Darryl Turner
    Sponsored By: Thermo Fisher Scientific
    20
    JUL 10, 2025 | 8:00 AM
    Clinical applications of Sanger sequencing and fragment analysis via capillary electrophoresis and an introduction to the SeqStudio Flex Dx Genetic Analyzer
    Clinical applications of Sanger sequencing and fragment analysis...
    Due to its high accuracy and fast, simple workflow, Capillary Electrophoresis (CE) is a foundational technology for clinical applications. CE is an invaluable tool used to detect genetic var...
    Speaker: Andy McNamara , Ramona Polster
    Sponsored By: Thermo Fisher Scientific
    13
    MAY 08, 2025 | 8:00 AM
    Applications of Surface Plasmon Resonance (SPR) in HIV-1 Nef Inhibitor Discovery and PROTAC Development
    Applications of Surface Plasmon Resonance (SPR) in HIV-1 Nef Inhibitor...
    The HIV-1 Nef accessory factor promotes viral replication and immune escape of HIV-infected cells, making it an attractive drug target. Our team previously identified small molecules that bi...
    Speaker: Thomas Smithgall, Ph.D.
    Sponsored By: Ametek
    10
    APR 30, 2025 | 8:00 AM
    MAFG: A key regulator in melanoma progression and a potential therapeutic target
    MAFG: A key regulator in melanoma progression and a potential...
    The MAF bZIP Transcription Factor G (MAFG) is a member of the small MAF family of proteins. Previously, we have shown that miRNA-29 suppresses melanoma development, at least in part, by repr...
    Speaker: Olga Puente, PhD
    Sponsored By: Thermo Fisher Scientific
    14 2
     
     
  • APR 08, 2025 | 8:00 AM
    Transfection Potency of Lipid Nanoparticles Containing mRNA Depends on Relative Loading Levels
    Transfection Potency of Lipid Nanoparticles Containing mRNA Depends...
    When formulating mRNA into lipid nanoparticles (LNP), various copy numbers of mRNA are encapsulated, leading to a distribution of mRNA loading levels within the LNPs. It is unclear whether t...
    Speaker: Dr. Suiyang Liao
    Sponsored By: Beckman Coulter Life Sciences
    13 1
    APR 03, 2025 | 8:00 AM
    C.E. CREDITS
    Best Practices for Clinical Labs in Turbulent Times
    Best Practices for Clinical Labs in Turbulent Times
    The FDA’s landmark final rule on Laboratory Developed Tests (LDTs) is set to transform the regulatory landscape for diagnostic laboratories. This webinar will provide biomedical diagno...
    Speaker: Michael J. Donovan, Ph.D., JD , Travis Schlappi, PhD , Mara G. Aspinall, MBA
    Sponsored By: Thermo Fisher Scientific
    36
    DEC 10, 2024 | 9:00 AM
    Advances in iPSC Workflows to Build Better Models and Therapies
    Advances in iPSC Workflows to Build Better Models and Therapies
    At Thermo Fisher Scientific, our goal is to bring innovative new products and services that enable the development of more physiologically relevant disease models to help accelerate the drug...
    Speaker: Omar Farah, Ph.D.
    Sponsored By: Thermo Fisher Scientific
    15
    NOV 13, 2024 | 10:00 AM
    Single Cell Multiomic characterization of pediatric gliomas uncover novel, subtype-specific therapeutic approaches
    Single Cell Multiomic characterization of pediatric gliomas uncover...
    Brain tumors are the leading cause of solid-tumor-related deaths among children. These tumors are now categorized by WHO as separated from adult brain tumors and based on their distinct mole...
    Speaker: David Rincón Fernández Pacheco, PhD
    Sponsored By: Scale Biosciences
    8
    OCT 16, 2024 | 9:00 AM
    C.E. CREDITS
    Keynote Presentation: The Trials & Tribulations of the Clinical Diagnostic Landscape with Live Q&A
    Keynote Presentation: The Trials & Tribulations of the Clinical...
    In today’s diagnostic test development landscape, the path to commercialization and generating topline revenue is marked by peaks and valleys. One of the first hurdles is navigating th...
    Speaker: Lesley E. Northrop, PhD, FACMG
    Presented at: Cell & Gene Therapy Virtual Event Series 2024
    6
     
     
  • On Demand
    C.E. CREDITS
    In Vivo Correction of Human Phenylketonuria Variants via Prime Editing and Base Editing: A Gateway to Equitable Treatment of Inborn Errors of Metabolism
    In Vivo Correction of Human Phenylketonuria Variants via Prime...
    Inborn errors of metabolism (IEMs) are rare, devastating disorders caused by pathogenic variants in genes encoding key metabolic enzymes, with the liver playing a critical role in over 140 I...
    Speaker: Xiao Wang, PhD
    Presented at: Cell & Gene Therapy Virtual Event Series 2024
    6
    On Demand
    C.E. CREDITS
    Hypertonic Saline Remarkably Enhances Gene Transfer to Airway Epithelial Cells
    Hypertonic Saline Remarkably Enhances Gene Transfer to Airway...
    A fundamental challenge for cystic fibrosis (CF) gene therapy is ensuring sufficient transduction of airway epithelial cells to achieve therapeutic correction. Vehicles such as lysophosphati...
    Speaker: Ashley Cooney, PhD
    Presented at: Cell & Gene Therapy Virtual Event Series 2024
    5 1
    OCT 02, 2024 | 11:00 AM
    Exploring myeloid cell heterogeneity in autoimmune skin diseases with novel multiomics insights
    Exploring myeloid cell heterogeneity in autoimmune skin diseases...
    Inflammatory skin disorders comprise a diverse set of conditions exhibiting unique characteristics. Our objective was to systematically compare the affected and unaffected skin of individual...
    Speaker: Khashayar Afshari, MD, MPH
    Sponsored By: Olink Proteomics
    11
    On Demand
    C.E. CREDITS
    Next Generation Genetic Discovery Systems in Human Immune Cells
    Next Generation Genetic Discovery Systems in Human Immune Cells
    Engineered immune cell therapies offer the promise of more tailored interventions than traditional systemic checkpoint blockades, but so far remain ineffective across the majority of clinica...
    Speaker: Theodore Roth, MD, PhD
    Presented at: Cancer Research & Oncology Virtual Event Series 2024
    2
    SEP 18, 2024 | 9:00 AM
    C.E. CREDITS
    Keynote Presentation: Applications of Cellular Assays for Understanding Drug Disposition of Protein Therapeutics with Live Q&A
    Keynote Presentation: Applications of Cellular Assays for Understanding...
    The disposition of antibody-based therapeutics is generally determined by both target-mediated and non-target processes, the latter being an often-overlooked aspect. Target-independent liabi...
    Speaker: Mark Bryniarski, PhD, MS
    Presented at: Cell Biology Virtual Event Series 2024
    3
     
     
  • On Demand
    C.E. CREDITS
    Microphysiological Systems Research: Applications in  Biopharmaceutics and Advancements in Image Analysis
    Microphysiological Systems Research: Applications in Biopharmaceutics...
    A microphysiological system is a 3D in vitro model that mimics human tissue environments with high physiological relevance. This approach enhances our understanding of disease mechanisms, dr...
    Speaker: Eunkyung (Clare) Ko, PhD , Devin Wakefield
    Presented at: Cell Biology Virtual Event Series 2024
    4
    On Demand
    C.E. CREDITS
    Human-On-a-Chip Systems For Use in Therapeutic Index Determination and Systemic Toxicity in Pre-Clinical Drug Discovery Applications
    Human-On-a-Chip Systems For Use in Therapeutic Index Determination...
    One of the primary limitations in drug discovery and toxicology research is the lack of good model systems between the single cell level and animal or human systems. This is especially true...
    Speaker: James J. Hickman, PhD
    Presented at: Cell Biology Virtual Event Series 2024
    3
    AUG 29, 2024 | 7:00 AM
    Unleashing the Potential of mRNA Synthesis: A Deep Dive into Solid-phase In vitro Transcription
    Unleashing the Potential of mRNA Synthesis: A Deep Dive into Solid-phase...
    Unlocking the potential of mRNA technology is revolutionizing medicine and biotechnology. Solid-phase in vitro transcription enables scalability and automation, making it a valuable tool for...
    Speaker: Iwona Grad, Ph.D
    Sponsored By: Thermo Fisher Scientific
    18
    JUN 27, 2024 | 7:00 AM
    Trace-level cytokines and cardiovascular profiling for long-term COVID diagnostic
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    Globally, over 65 million individuals are estimated to suffer from post-acute sequelae of COVID-19 (PASC). A large number of individuals living with PASC experience cardiovascular symptoms (...
    Speaker: Kirsty Short , Sonja Stoelzle-Feix
    Sponsored By: Nanion Technologies
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