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    Method optimization

    In medical research, method optimization evaluates ways to minimize or maximize specific parameters of a study. Optimization can involve parameters such as reducing the costs associated with a procedure, limiting the materials required to develop an assay, or obtaining maximal productivity from a technique.

    Webinars

    • OCT 06, 2021 | 9:00 AM
      Monitoring Tumor Microenvironment Immunotherapeutic Impact in Heterogeneous Cancer: Prostate Cancer, Spatial Transcriptomics, and a Novel Therapeutic Target B7-H3
      Monitoring Tumor Microenvironment Immunotherapeutic Impact in...
      Background: Localized prostate cancer is notable for tumor heterogeneity, and immune heterogeneity within tumor versus benign areas. B7-H3, a member of the B7 superfamily, is highly expresse...
      Speaker: Eugene Shenderov, MD, DPhil, FACP
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2021
      Sponsored By: NanoString Technologies
      1
      OCT 05, 2021 | 7:00 AM
      Resolving Challenges in Flow Cytometry Panel Design
      Resolving Challenges in Flow Cytometry Panel Design
      Date: October 05, 2021 Time: 7:00am (PDT), 10:00am (EDT) After new users become familiar with flow cytometry instrumentation and learn how to set up the instrument and acquire data, the next...
      Speaker: Michael Kapinsky, PhD , Matthew Goff
      Sponsored By: Beckman Coulter Life Sciences
      13 1
      SEP 23, 2021 | 9:00 AM
      Tubulin or Not Tubulin? Heading towards total protein staining as a loading control in immunological protein analytical methods
      Tubulin or Not Tubulin? Heading towards total protein staining...
      Date: September 23, 2021 Time: 9:00am (PDT), 12:00pm (EDT) Western blotting and other immunological protein-analytical methods are widely used for detecting and (semi-)quantifying specific p...
      Speaker: Christian Moritz, PhD
      Sponsored By: ProteinSimple
      3
      SEP 09, 2021 | 7:30 AM
      DNA Synthesis for mRNA Therapeutics: How to ensure good results by choosing the right DNA
      DNA Synthesis for mRNA Therapeutics: How to ensure good results...
      Over the last two decades, DNA synthesis has established itself as a standard tool propelling life science research in a wide range of fields. In this session, we will highlight how DNA synt...
      Speaker: Axel Trefzer, PhD
      Presented at: Microbiology Week Virtual Event Series 2021
      Sponsored By: Thermo Fisher Scientific
      1
      SEP 09, 2021 | 12:00 AM
      AtbFinder: A New Diagnostic Tool for the Selection of Optimal Antibiotics for Patients with Drug-Resistant Bacterial Infections
      AtbFinder: A New Diagnostic Tool for the Selection of Optimal...
      Existing methods for antibiotic selection are based on outdated and inaccurate microbiological principles, causing millions of inappropriate antibiotic selections and hundreds of thousands o...
      Speaker: George Tetz, MD, PhD
      Presented at: Microbiology Week Virtual Event Series 2021
      0
      AUG 26, 2021 | 8:00 AM
      Serum-free Expansion of NK Cells with K562-  Based Feeder Systems for Clinical Applications
      Serum-free Expansion of NK Cells with K562- Based Feeder Systems...
      Date: August 26, 2021 Time: 8:00am (PDT), 11:00am (EDT) My translational research program focuses on approaches to enhance the natural killer (NK) cell response to cancer, with an emphasis o...
      Speaker: Dean Lee, MD, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      7
      AUG 25, 2021 | 8:00 AM
      Improving heterologous protein production in yeast with massively parallel CRISPR genome editing
      Improving heterologous protein production in yeast with massively...
      Date: August 25, 2021 Time: 8:00am (PDT), 11:00am (EDT) Heterologous protein production is an indispensable tool in biotechnology and biopharma for manufacturing enzymes, protein therapeutic...
      Speaker: Eric Abbate
      Sponsored By: Inscripta
      5 2
      AUG 25, 2021 | 12:00 AM
      Learning Electrical Connectomes of Neuropsychiatric Disorders and Behaviors
      Learning Electrical Connectomes of Neuropsychiatric Disorders...
      Targeted stimulation of the brain has the potential to treat mental illnesses but designing an appropriate protocol requires a multitude of choices. I will describe an approach to help desig...
      Speaker: David Carlson, PhD
      Presented at: Neuroscience Virtual Event Series 2021
      1
      AUG 25, 2021 | 12:00 AM
      Rational Thoughts in Neural Codes
      Rational Thoughts in Neural Codes
      Complex behaviors are often driven by an internal model, which integrates sensory information over time and facilitates long-term planning to reach subjective goals. {\color{rev}A fundamenta...
      Speaker: Xaq Pitkow, Ph.D.
      Presented at: Neuroscience Virtual Event Series 2021
      1
      AUG 25, 2021 | 12:00 AM
      Mechanistic Insight into Tandem Repeat Expansions in Amyotrophic Lateral Sclerosis
      Mechanistic Insight into Tandem Repeat Expansions in Amyotrophic...
      Over 40 tandem repeats undergo expansion events that lead to neurological disease. This number is likely an underestimate as many repeats are difficult to amplify using existing short read s...
      Speaker: Paul Valdmanis, PhD
      Presented at: Neuroscience Virtual Event Series 2021
      Sponsored By: PacBio
      1
      JUL 22, 2021 | 4:15 PM
      Discovering the Next Generation AAV Vector Through Capsid Engineering and Expression Cassette Optimization
      Discovering the Next Generation AAV Vector Through Capsid Engineering...
      Learning Objectives: 1. Background introduction to AAV gene therapy 2. Novel methods to build AAV capsid libraries for in vivo screening through rational design and directed evolution 3. Tis...
      Speaker: Ye Liu, PhD
      Presented at: GenScript Gene & Cell Engineering Virtual Summit
      1
      JUL 15, 2021 | 2:00 PM
      C.E. CREDITS
      Lupus anticoagulants and antiphospholipid syndrome: Resolving confusion, providing new guideline updates
      Lupus anticoagulants and antiphospholipid syndrome: Resolving...
      Join our session on antiphospholipid syndrome covering diagnosis, antibody testing, guideline updates, and clinical insights....
      Speaker: Thomas Ortel, MD, PhD
      Presented at: Stago EdVantage Virtual University
      Sponsored By: Diagnostica Stago, Inc.
      11
      JUN 29, 2021 | 11:00 AM
      Advancing Cellular Ultrastructure Research with Freeze-Fracture and Freeze-Etching
      Advancing Cellular Ultrastructure Research with Freeze-Fracture...
      Date: June 29, 2021 Time: 11:00am (PDT), 02:00pm (EDT) Freeze-fracture and freeze-etching are useful tools for studying flexible membrane-associated structures such as tight junctions or the...
      Speaker: Evan Krystofiak , Seth Villarreal
      Sponsored By: Leica Microsystems
      9 1
      JUN 16, 2021 | 8:00 AM
      Simplicity that defies complexity - the MACSima™ Platform for ultrahigh-content imaging
      Simplicity that defies complexity - the MACSima™ Platform for...
      Date: June 16, 2021 Time: 8:00am PDT The MACSima™ Imaging Platform is the only complete solution for ultrahigh-content imaging of hundreds of markers, allowing you to understand the tu...
      Speaker: Dr. Ali Kinkhabwala , Dr. Markus Habich
      Sponsored By: Miltenyi Biotec
      7
      JUN 10, 2021 | 7:30 AM
      Opening Keynote: LC-MS and Healthcare: Powerful Tools To Address Complex Questions
      Opening Keynote: LC-MS and Healthcare: Powerful Tools To Address...
      The state of healthcare today and tomorrow can be best described as complex and unpredictable. From chronic diseases to neurodegenerative diseases such as Alzheimer’s, infectious disea...
      Speaker: Bill Clarke, PhD, MBA, DABCC
      Presented at: Shaping the Future of LC-MS in Life Science Together
      1
      JUN 09, 2021 | 8:10 AM
      Characterization of mRNA Therapeutics using Automated LC-MS Workflows
      Characterization of mRNA Therapeutics using Automated LC-MS Workflows
      The analysis of oligonucleotide and mRNA therapeutics requires robust and accurate analytical characterization to confirm identity, and to determine purity and quality....
      Speaker: Professor Mark Dickman
      Presented at: Shaping the Future of LC-MS in Life Science Together
      2
      JUN 09, 2021 | 7:00 AM
      Preventing cell misidentification in your daily lab routine
      Preventing cell misidentification in your daily lab routine
      Date: June 9, 2021 Time: 09 June 2021, 7am PDT, 10am EDT, 4pm CEST cells with dramatic implications on the validity of past cell culture related research. The fact that at least 509 cell lin...
      Speaker: Gabriela Saldanha , Jessica Wagener, PhD
      Sponsored By: Eppendorf
      40 3
      JUN 03, 2021 | 12:00 PM
      Utilizing the Gibco CTS Rotea System for cell and gene therapy development
      Utilizing the Gibco CTS Rotea System for cell and gene therapy...
      DATE: June 3, 2021 TIME: 12:00pm SGT This webinar is a virtual event that focuses on utilizing the Gibco CTS Rotea System for Cell and Gene Therapy...
      Speaker: Premkumar Jayaraman, PhD , Emily Benz , Eric Dubofsky
      Sponsored By: Thermo Fisher Scientific
      5
      JUN 02, 2021 | 8:00 AM
      Exploiting digital histology approaches to probe the pathophysiology of SARS-CoV-2 infection
      Exploiting digital histology approaches to probe the pathophysiology...
      Date: June 2, 2021 Time: 8:00am (PDT), 11:00am (EDT) In this introduction Kelly Hunter will address the first Learning Objective. He will cover i) a range of digital pathology and tissue mul...
      Speaker: Kelly Hunter, BSc Biochemistry, MSc Genomics Medicine , Dr. Graham Taylor, BSc, Ph.D
      Sponsored By: Leica Biosystems
      11 1
      MAY 26, 2021 | 10:00 AM
      How Busulfan testing improved the management of Bone Marrow Transplant Patients
      How Busulfan testing improved the management of Bone Marrow Transplant...
      Date: May 25, 2021 Time: 7:00pm PDT Therapeutic drug monitoring (TDM) of Busulfan is essential for management of Bone Marrow Transplant (BMT) patients, by optimizing dose, s...
      Speaker: Esther Lazo, MS
      Sponsored By: Waters Corporation
      1
      MAY 25, 2021 | 6:00 AM
      How Busulfan testing improved the management of Bone Marrow Transplant Patients
      How Busulfan testing improved the management of Bone Marrow Transplant...
      Date: May 25, 2021 Time: 8:00am (PST), 11:00am (EST) Therapeutic drug monitoring (TDM) of Busulfan is essential for management of Bone Marrow Transplant (BMT) patients, by optimizing dose, s...
      Speaker: Esther Lazo, MS
      Sponsored By: Waters Corporation
      7 1
      MAY 19, 2021 | 12:00 AM
      Efficient Method Validation Workflow with Full Device Integration
      Efficient Method Validation Workflow with Full Device Integration
      Analytical Method Validation work is based on a variety of guidelines and requirements hence being time-consuming and stressful. Reducing this work and improving efficiency while ensuring th...
      Speaker: Jürgen Voorgang
      Presented at: Laboratory Automation Virtual Event Series 2021
      1
      MAY 06, 2021 | 7:00 AM
      Everyday Cell Culture Practice - Improve reproducibility of your cell culture
      Everyday Cell Culture Practice - Improve reproducibility of your...
      Date: May 6, 2021 Time: 7:00am PDT, 10:00am EDT, 4:00pm CEST Eukaryotic cell cultures respond to the most subtle influence. Apart from the risk of contamination, minimal changes in cultivati...
      Speaker: Jessica Wagener, PhD
      Sponsored By: Eppendorf
      29
      APR 29, 2021 | 9:00 AM
      Cryo-Electron Microscopy: membrane proteins down to atoms
      Cryo-Electron Microscopy: membrane proteins down to atoms
      Date: April 29, 2021 Time: 9:00am PST Cryo-electron microscopy (cryo-EM) reached single-atom resolution for 3D structure determination of biological macromolecules. Cryo-EM has been determin...
      Speaker: Stephen Brohawn, PhD , Abhay Kotecha, PhD , Marc Storms
      Presented at: Thermo Fisher Scientific - Electron Microscopy Webinars
      Sponsored By: Thermo Fisher Scientific
      8
    OCT 06, 2021 | 9:00 AM
    Monitoring Tumor Microenvironment Immunotherapeutic Impact in Heterogeneous Cancer: Prostate Cancer, Spatial Transcriptomics, and a Novel Therapeutic Target B7-H3
    Monitoring Tumor Microenvironment Immunotherapeutic Impact in...
    Background: Localized prostate cancer is notable for tumor heterogeneity, and immune heterogeneity within tumor versus benign areas. B7-H3, a member of the B7 superfamily, is highly expresse...
    Speaker: Eugene Shenderov, MD, DPhil, FACP
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2021
    Sponsored By: NanoString Technologies
    1
    OCT 05, 2021 | 7:00 AM
    Resolving Challenges in Flow Cytometry Panel Design
    Resolving Challenges in Flow Cytometry Panel Design
    Date: October 05, 2021 Time: 7:00am (PDT), 10:00am (EDT) After new users become familiar with flow cytometry instrumentation and learn how to set up the instrument and acquire data, the next...
    Speaker: Michael Kapinsky, PhD , Matthew Goff
    Sponsored By: Beckman Coulter Life Sciences
    13 1
    SEP 23, 2021 | 9:00 AM
    Tubulin or Not Tubulin? Heading towards total protein staining as a loading control in immunological protein analytical methods
    Tubulin or Not Tubulin? Heading towards total protein staining...
    Date: September 23, 2021 Time: 9:00am (PDT), 12:00pm (EDT) Western blotting and other immunological protein-analytical methods are widely used for detecting and (semi-)quantifying specific p...
    Speaker: Christian Moritz, PhD
    Sponsored By: ProteinSimple
    3
    SEP 09, 2021 | 7:30 AM
    DNA Synthesis for mRNA Therapeutics: How to ensure good results by choosing the right DNA
    DNA Synthesis for mRNA Therapeutics: How to ensure good results...
    Over the last two decades, DNA synthesis has established itself as a standard tool propelling life science research in a wide range of fields. In this session, we will highlight how DNA synt...
    Speaker: Axel Trefzer, PhD
    Presented at: Microbiology Week Virtual Event Series 2021
    Sponsored By: Thermo Fisher Scientific
    1
    SEP 09, 2021 | 12:00 AM
    AtbFinder: A New Diagnostic Tool for the Selection of Optimal Antibiotics for Patients with Drug-Resistant Bacterial Infections
    AtbFinder: A New Diagnostic Tool for the Selection of Optimal...
    Existing methods for antibiotic selection are based on outdated and inaccurate microbiological principles, causing millions of inappropriate antibiotic selections and hundreds of thousands o...
    Speaker: George Tetz, MD, PhD
    Presented at: Microbiology Week Virtual Event Series 2021
    0
     
     
  • AUG 26, 2021 | 8:00 AM
    Serum-free Expansion of NK Cells with K562-  Based Feeder Systems for Clinical Applications
    Serum-free Expansion of NK Cells with K562- Based Feeder Systems...
    Date: August 26, 2021 Time: 8:00am (PDT), 11:00am (EDT) My translational research program focuses on approaches to enhance the natural killer (NK) cell response to cancer, with an emphasis o...
    Speaker: Dean Lee, MD, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    7
    AUG 25, 2021 | 8:00 AM
    Improving heterologous protein production in yeast with massively parallel CRISPR genome editing
    Improving heterologous protein production in yeast with massively...
    Date: August 25, 2021 Time: 8:00am (PDT), 11:00am (EDT) Heterologous protein production is an indispensable tool in biotechnology and biopharma for manufacturing enzymes, protein therapeutic...
    Speaker: Eric Abbate
    Sponsored By: Inscripta
    5 2
    AUG 25, 2021 | 12:00 AM
    Learning Electrical Connectomes of Neuropsychiatric Disorders and Behaviors
    Learning Electrical Connectomes of Neuropsychiatric Disorders...
    Targeted stimulation of the brain has the potential to treat mental illnesses but designing an appropriate protocol requires a multitude of choices. I will describe an approach to help desig...
    Speaker: David Carlson, PhD
    Presented at: Neuroscience Virtual Event Series 2021
    1
    AUG 25, 2021 | 12:00 AM
    Rational Thoughts in Neural Codes
    Rational Thoughts in Neural Codes
    Complex behaviors are often driven by an internal model, which integrates sensory information over time and facilitates long-term planning to reach subjective goals. {\color{rev}A fundamenta...
    Speaker: Xaq Pitkow, Ph.D.
    Presented at: Neuroscience Virtual Event Series 2021
    1
    AUG 25, 2021 | 12:00 AM
    Mechanistic Insight into Tandem Repeat Expansions in Amyotrophic Lateral Sclerosis
    Mechanistic Insight into Tandem Repeat Expansions in Amyotrophic...
    Over 40 tandem repeats undergo expansion events that lead to neurological disease. This number is likely an underestimate as many repeats are difficult to amplify using existing short read s...
    Speaker: Paul Valdmanis, PhD
    Presented at: Neuroscience Virtual Event Series 2021
    Sponsored By: PacBio
    1
     
     
  • JUL 22, 2021 | 4:15 PM
    Discovering the Next Generation AAV Vector Through Capsid Engineering and Expression Cassette Optimization
    Discovering the Next Generation AAV Vector Through Capsid Engineering...
    Learning Objectives: 1. Background introduction to AAV gene therapy 2. Novel methods to build AAV capsid libraries for in vivo screening through rational design and directed evolution 3. Tis...
    Speaker: Ye Liu, PhD
    Presented at: GenScript Gene & Cell Engineering Virtual Summit
    1
    JUL 15, 2021 | 2:00 PM
    C.E. CREDITS
    Lupus anticoagulants and antiphospholipid syndrome: Resolving confusion, providing new guideline updates
    Lupus anticoagulants and antiphospholipid syndrome: Resolving...
    Join our session on antiphospholipid syndrome covering diagnosis, antibody testing, guideline updates, and clinical insights....
    Speaker: Thomas Ortel, MD, PhD
    Presented at: Stago EdVantage Virtual University
    Sponsored By: Diagnostica Stago, Inc.
    11
    JUN 29, 2021 | 11:00 AM
    Advancing Cellular Ultrastructure Research with Freeze-Fracture and Freeze-Etching
    Advancing Cellular Ultrastructure Research with Freeze-Fracture...
    Date: June 29, 2021 Time: 11:00am (PDT), 02:00pm (EDT) Freeze-fracture and freeze-etching are useful tools for studying flexible membrane-associated structures such as tight junctions or the...
    Speaker: Evan Krystofiak , Seth Villarreal
    Sponsored By: Leica Microsystems
    9 1
    JUN 16, 2021 | 8:00 AM
    Simplicity that defies complexity - the MACSima™ Platform for ultrahigh-content imaging
    Simplicity that defies complexity - the MACSima™ Platform for...
    Date: June 16, 2021 Time: 8:00am PDT The MACSima™ Imaging Platform is the only complete solution for ultrahigh-content imaging of hundreds of markers, allowing you to understand the tu...
    Speaker: Dr. Ali Kinkhabwala , Dr. Markus Habich
    Sponsored By: Miltenyi Biotec
    7
    JUN 10, 2021 | 7:30 AM
    Opening Keynote: LC-MS and Healthcare: Powerful Tools To Address Complex Questions
    Opening Keynote: LC-MS and Healthcare: Powerful Tools To Address...
    The state of healthcare today and tomorrow can be best described as complex and unpredictable. From chronic diseases to neurodegenerative diseases such as Alzheimer’s, infectious disea...
    Speaker: Bill Clarke, PhD, MBA, DABCC
    Presented at: Shaping the Future of LC-MS in Life Science Together
    1
     
     
  • JUN 09, 2021 | 8:10 AM
    Characterization of mRNA Therapeutics using Automated LC-MS Workflows
    Characterization of mRNA Therapeutics using Automated LC-MS Workflows
    The analysis of oligonucleotide and mRNA therapeutics requires robust and accurate analytical characterization to confirm identity, and to determine purity and quality....
    Speaker: Professor Mark Dickman
    Presented at: Shaping the Future of LC-MS in Life Science Together
    2
    JUN 09, 2021 | 7:00 AM
    Preventing cell misidentification in your daily lab routine
    Preventing cell misidentification in your daily lab routine
    Date: June 9, 2021 Time: 09 June 2021, 7am PDT, 10am EDT, 4pm CEST cells with dramatic implications on the validity of past cell culture related research. The fact that at least 509 cell lin...
    Speaker: Gabriela Saldanha , Jessica Wagener, PhD
    Sponsored By: Eppendorf
    40 3
    JUN 03, 2021 | 12:00 PM
    Utilizing the Gibco CTS Rotea System for cell and gene therapy development
    Utilizing the Gibco CTS Rotea System for cell and gene therapy...
    DATE: June 3, 2021 TIME: 12:00pm SGT This webinar is a virtual event that focuses on utilizing the Gibco CTS Rotea System for Cell and Gene Therapy...
    Speaker: Premkumar Jayaraman, PhD , Emily Benz , Eric Dubofsky
    Sponsored By: Thermo Fisher Scientific
    5
    JUN 02, 2021 | 8:00 AM
    Exploiting digital histology approaches to probe the pathophysiology of SARS-CoV-2 infection
    Exploiting digital histology approaches to probe the pathophysiology...
    Date: June 2, 2021 Time: 8:00am (PDT), 11:00am (EDT) In this introduction Kelly Hunter will address the first Learning Objective. He will cover i) a range of digital pathology and tissue mul...
    Speaker: Kelly Hunter, BSc Biochemistry, MSc Genomics Medicine , Dr. Graham Taylor, BSc, Ph.D
    Sponsored By: Leica Biosystems
    11 1
    MAY 26, 2021 | 10:00 AM
    How Busulfan testing improved the management of Bone Marrow Transplant Patients
    How Busulfan testing improved the management of Bone Marrow Transplant...
    Date: May 25, 2021 Time: 7:00pm PDT Therapeutic drug monitoring (TDM) of Busulfan is essential for management of Bone Marrow Transplant (BMT) patients, by optimizing dose, s...
    Speaker: Esther Lazo, MS
    Sponsored By: Waters Corporation
    1
     
     
  • MAY 25, 2021 | 6:00 AM
    How Busulfan testing improved the management of Bone Marrow Transplant Patients
    How Busulfan testing improved the management of Bone Marrow Transplant...
    Date: May 25, 2021 Time: 8:00am (PST), 11:00am (EST) Therapeutic drug monitoring (TDM) of Busulfan is essential for management of Bone Marrow Transplant (BMT) patients, by optimizing dose, s...
    Speaker: Esther Lazo, MS
    Sponsored By: Waters Corporation
    7 1
    MAY 19, 2021 | 12:00 AM
    Efficient Method Validation Workflow with Full Device Integration
    Efficient Method Validation Workflow with Full Device Integration
    Analytical Method Validation work is based on a variety of guidelines and requirements hence being time-consuming and stressful. Reducing this work and improving efficiency while ensuring th...
    Speaker: Jürgen Voorgang
    Presented at: Laboratory Automation Virtual Event Series 2021
    1
    MAY 06, 2021 | 7:00 AM
    Everyday Cell Culture Practice - Improve reproducibility of your cell culture
    Everyday Cell Culture Practice - Improve reproducibility of your...
    Date: May 6, 2021 Time: 7:00am PDT, 10:00am EDT, 4:00pm CEST Eukaryotic cell cultures respond to the most subtle influence. Apart from the risk of contamination, minimal changes in cultivati...
    Speaker: Jessica Wagener, PhD
    Sponsored By: Eppendorf
    29
    APR 29, 2021 | 9:00 AM
    Cryo-Electron Microscopy: membrane proteins down to atoms
    Cryo-Electron Microscopy: membrane proteins down to atoms
    Date: April 29, 2021 Time: 9:00am PST Cryo-electron microscopy (cryo-EM) reached single-atom resolution for 3D structure determination of biological macromolecules. Cryo-EM has been determin...
    Speaker: Stephen Brohawn, PhD , Abhay Kotecha, PhD , Marc Storms
    Presented at: Thermo Fisher Scientific - Electron Microscopy Webinars
    Sponsored By: Thermo Fisher Scientific
    8
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