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    Method optimization

    In medical research, method optimization evaluates ways to minimize or maximize specific parameters of a study. Optimization can involve parameters such as reducing the costs associated with a procedure, limiting the materials required to develop an assay, or obtaining maximal productivity from a technique.

    Webinars

    • APR 28, 2021 | 8:00 AM
      How to optimize your shake flask and bioreactor cultures
      How to optimize your shake flask and bioreactor cultures
      DATE: April 28, 2021 TIME: 08am PST Shakers and bioreactors are established versatile systems for cultivating microorganism, plant, and animal cells in suspension. Both methods aim at increa...
      Speaker: Ines Hartmann , Ankita Desai
      Sponsored By: Eppendorf
      16
      APR 22, 2021 | 10:30 AM
      Extraction-free sensitive detection of viral RNA using direct RT-PCR chemistry
      Extraction-free sensitive detection of viral RNA using direct...
      Nucleic acid amplification tests (NAAT) are a reliable, sensitive, and accurate diagnostic approach used in viral detection. The approach involves the isolation of nucleic acids from a sampl...
      Speaker: Donald Green
      Presented at: Genetics Week Virtual Event Series 2021
      Sponsored By: Cytiva
      4 1
      APR 22, 2021 | 9:00 AM
      Shield of safety: Protecting the clinical lab
      Shield of safety: Protecting the clinical lab
      Date: April 22, 2021 Time: 9:00am (PST), 12:00pm (EST) The clinical lab is a collection of numerous complex workflows. It is imperative that not only specimens are protected from contaminati...
      Speaker: Ryann Rios , Jordan Henderson
      Sponsored By: Labconco
      8
      APR 21, 2021 | 12:00 PM
      Directed evolution - shrinking the haystack with tailor-made synthetic DNA
      Directed evolution - shrinking the haystack with tailor-made synthetic...
      Directed evolution is an effective strategy to optimize the properties of proteins for specific requirements, either for industrial, therapeutics or research applications. As the theoretical...
      Speaker: Dr. Tobias Santl, PhD
      Presented at: Genetics Week Virtual Event Series 2021
      Sponsored By: Thermo Fisher Scientific
      1
      APR 21, 2021 | 10:30 AM
      Panel Presentation: Driving lab efficiency with PCR power
      Panel Presentation: Driving lab efficiency with PCR power
      Detection and/or amplification of target DNA sequences by polymerase chain reaction (PCR) is a prevalent method in molecular biology. PCR has a broad range of applications, including use in...
      Speaker: Kyle Hondorp , Marija Navickaitė
      Presented at: Genetics Week Virtual Event Series 2021
      Sponsored By: Thermo Fisher Scientific
      3
      APR 21, 2021 | 12:00 AM
      Saliva - based testing for SARS-CoV-2 diagnosis
      Saliva - based testing for SARS-CoV-2 diagnosis
      Historically, nasopharyngeal sampling has been considered the gold standard for the detection of most upper respiratory tract infections, however major medical and laboratory supply chain is...
      Speaker: Orchid Allicock, PhD
      Presented at: Genetics Week Virtual Event Series 2021
      1
      APR 14, 2021 | 3:00 PM
      NEXTFLEX® Variant-Seq™ SARS-CoV-2 Kit
      NEXTFLEX® Variant-Seq™ SARS-CoV-2 Kit
      As of March 2021, SARS-CoV-2 has infected 115 million people and caused over 2.56 million deaths. The emergence of mutants associated with changes to transmission of SARS-CoV-2 has shown tha...
      Speaker: Pedro Echave, PhD
      Presented at: Coronavirus Series
      Sponsored By: PerkinElmer
      2
      APR 08, 2021 | 11:00 AM
      Pneumonia Diagnosis: Bacterial Superinfection in COVID-19 Patients
      Pneumonia Diagnosis: Bacterial Superinfection in COVID-19 Patients
      Date: April 8, 2021 Time: 11:00am (PDT), 3:00pm (EDT) Pneumonia is a deadly condition with clinical outcomes highly dependent on prompt and appropriate therapy. Diagnosis of pneumonia is cha...
      Speaker: Christian Giske, MD, PhD , Drew Bell, PhD
      Sponsored By: OpGen, Inc.
      18 3
      APR 07, 2021 | 2:15 PM
      Gene Editing Validation with Highly-Accurate HiFi Reads
      Gene Editing Validation with Highly-Accurate HiFi Reads
      In this fireside chat, we’ll discuss how gene editing protocols can benefit from long-read sequencing at various stages to optimize and enhance vector integrity, which cannot be addres...
      Speaker: Michael Weiand , Andrea O'Hara, Ph.D.
      Presented at: Advancing CGT: A GENEWIZ & Brooks Life Sciences Virtual Event
      1
      APR 07, 2021 | 9:00 AM
      Keynote Presentation: Doing more with less - Maximizing Phase Appropriate DOE Strategies
      Keynote Presentation: Doing more with less - Maximizing Phase...
      One challenge pharmaceutical companies face, is moving promising biotherapeutic products into the clinic as fast as safely possible. Devoting the correct amount of time and resources to earl...
      Speaker: Patricia McNeill
      Presented at: Bioprocessing Virtual Event Series 2021
      Sponsored By: Roche Diagnostics
      1
      MAR 30, 2021 | 8:00 AM
      Utilizing the Gibco™ CTS™ Rotea™ System, a versatile closed manufacturing system, for cell and gene therapy development
      Utilizing the Gibco™ CTS™ Rotea™ System, a versatile closed manufacturing...
      DATE: March 30, 2021 TIME: 08:00am PST In this talk, we will discuss the value of moving towards modular and automated, closed-system technologies designed to enable scalable and cost-effect...
      Speaker: Mary Ann Santos , Emily Benz , Eric Dubofsky
      Sponsored By: Thermo Fisher Scientific/Gibco
      6
      MAR 30, 2021 | 7:00 AM
      Method optimization of CE-SDS for the next generation of protein biologics
      Method optimization of CE-SDS for the next generation of protein...
      Date: March 30, 2021 Time: 7:00am (PDT), 10:00am (EDT) n this talk today we will discuss how to improve the resolution of your current CE-SDS methods. We will cover how CE-SDS works and what...
      Speaker: Marcus Heinl , Stephen Lock, PhD
      Sponsored By: SCIEX
      8 4
      MAR 24, 2021 | 9:00 AM
      Residual Nucleic Acid Characterization of Cell Culture-Produced Vaccines and Biologics
      Residual Nucleic Acid Characterization of Cell Culture-Produced...
      Date: March 24, 2021 Time: 9:00am (PST), 12:00pm (EST) Determination of residual host cell DNA and RNA are regulatory expectations as they pose potential safety concerns for cell culture-der...
      Speaker: Peter Holper, B.S. Biochemistry and Cell Biology
      Sponsored By: SCIEX
      14
      FEB 24, 2021 | 1:30 PM
      Roundtable Panel Presentation: Recent Trends in Screening GPCRs
      Roundtable Panel Presentation: Recent Trends in Screening GPCRs
      G protein-coupled receptors (GPCRs) are among the most intensively studied drug targets, and account for about ~34% of all drugs approved by the FDA. Examples of drugs targeting GPCRs includ...
      Speaker: Annette Gilchrist, PhD , Professor Kevin Pfleger, MA, PhD, FBPhS , Juan José Fung, PhD , Aarti Kawatkar , Yamina A. Berchiche, PhD , Ajay Yekkirala, PhD
      Presented at: Drug Discovery & Development Virtual Event Series 2021
      1
      FEB 10, 2021 | 12:00 AM
      Refining Pain Management for Laboratory Mice
      Refining Pain Management for Laboratory Mice
      Pain management includes the choice of analgesia agents, their dose, administration method, duration and frequency of treatment, and a pain-monitoring scheme for each individual animal. Insu...
      Speaker: Paulin Jirkof, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2021
      4
      FEB 03, 2021 | 12:30 PM
      Optimizing High-Content Imaging of 3D Models for Drug Discovery
      Optimizing High-Content Imaging of 3D Models for Drug Discovery
      In vitro spheroid models are fast becoming the de facto standard for drug discovery applications, largely due to their human-like physiological and morphological characteristics, tissue-like...
      Speaker: Arvonn Tully , Judi Wardwell-Swanson
      Presented at: 7th Annual Conference: SBI2 High Content
      Sponsored By: SBI2, InSphero , Yokogawa
      11 10
      DEC 10, 2020 | 9:00 AM
      Navigate the Pandemic through Laboratory Operational Excellence
      Navigate the Pandemic through Laboratory Operational Excellence
      DATE: December 10, 2020 TIME: 9:00am PST, 12:00pm EST Health systems across the globe continue to be challenged with aging populations, rising chronic diseases and changing care models....
      Speaker: Rouba Trad
      Sponsored By: Abbott Diagnostics
      3
      DEC 10, 2020 | 8:00 AM
      Simple and Fast Charge Variants Analysis of mAbs by CZE
      Simple and Fast Charge Variants Analysis of mAbs by CZE
      Date: December 10, 2020 Time: 8:00am (PST), 11:00am (EST) As you face increasingly shortened timelines to bring new drugs to market, you find yourself strained to finalize analytical methods...
      Speaker: Yan He, Ph.D.
      Sponsored By: SCIEX
      4 1
      DEC 04, 2020 | 5:00 AM
      Hemoglobin A1c: standardization, analytical performance and interference of Hb-variants.
      Hemoglobin A1c: standardization, analytical performance and interference...
      Date: December 04, 2020 Time: 5:00am PDT, 2:00pm CET Diabetes Mellitus has become a worldwide epidemic, affecting approximately 425 million people. Unfortunately, one in two patients remain...
      Speaker: Dr. Erna Lenters-Westra
      Sponsored By: Abbott Diagnostics
      17
      NOV 20, 2020 | 12:00 PM
      The Expanding Role of Microbiology in Antimicrobial Stewardship
      The Expanding Role of Microbiology in Antimicrobial Stewardship
      Date: September 30, 2020 Time: 9:00am (PDT), 12:00pm (EDT) Learning Objectives Why is Stewardship important? What are the core elements of stewardship and microbiology's role Importance...
      Speaker: Margie Morgan, PhD, D(ABMM), MT(ASCP) , Toni Beavers, PhD
      Sponsored By: BD
      14
      NOV 12, 2020 | 12:00 AM
      Fully Automated IHC Multiplexing: Techniques and Assay Development
      Fully Automated IHC Multiplexing: Techniques and Assay Development
      Multiplexing IHC is a technique that is increasing in demand as more and more researchers and physicians are being tasked with doing more with less. With multiplexing, you have the advantage...
      Speaker: Mark Hellewell, PhD
      Presented at: DISCOVERY Global User Symposium
      1
      NOV 10, 2020 | 9:00 AM
      Fast and reliable Gene Synthesis for optimized protein expression
      Fast and reliable Gene Synthesis for optimized protein expression
      DATE: November 10, 2020 TIME: 9:00am PT, 12am ET Gene Synthesis ensures fast access to nearly any DNA sequence, regardless its origin or complexity. Its reliability, flexibility and fast tur...
      Speaker: Claudia Chiocchini
      Sponsored By: Thermo Fisher Scientific
      19
      NOV 05, 2020 | 7:00 AM
      Stem cell derived exosome production in stirred-tank bioreactors
      Stem cell derived exosome production in stirred-tank bioreactors
      DATE: Date needed, 2020 TIME: Time needed Exosomes are a population of naturally occurring mobile, membrane-limited, 30 – 100 nm in diameter, extracellular vesicles containing a large...
      Speaker: Jorge Escobar , Aurélie Tacheny
      Presented at: Eppendorf Planet of Knowledge - A New Dimension
      Sponsored By: Eppendorf
      12
      OCT 22, 2020 | 8:00 AM
      Driving lab efficiency with PCR power
      Driving lab efficiency with PCR power
      Abstract: Detection and/or amplification of target DNA sequences by polymerase chain reaction (PCR) is a prevalent method in molecular biology. PCR has a broad range of applications, includi...
      Speaker: Kyle Hondorp , Marija Navickaitė
      Sponsored By: Thermo Fisher Scientific
      150 2
    APR 28, 2021 | 8:00 AM
    How to optimize your shake flask and bioreactor cultures
    How to optimize your shake flask and bioreactor cultures
    DATE: April 28, 2021 TIME: 08am PST Shakers and bioreactors are established versatile systems for cultivating microorganism, plant, and animal cells in suspension. Both methods aim at increa...
    Speaker: Ines Hartmann , Ankita Desai
    Sponsored By: Eppendorf
    16
    APR 22, 2021 | 10:30 AM
    Extraction-free sensitive detection of viral RNA using direct RT-PCR chemistry
    Extraction-free sensitive detection of viral RNA using direct...
    Nucleic acid amplification tests (NAAT) are a reliable, sensitive, and accurate diagnostic approach used in viral detection. The approach involves the isolation of nucleic acids from a sampl...
    Speaker: Donald Green
    Presented at: Genetics Week Virtual Event Series 2021
    Sponsored By: Cytiva
    4 1
    APR 22, 2021 | 9:00 AM
    Shield of safety: Protecting the clinical lab
    Shield of safety: Protecting the clinical lab
    Date: April 22, 2021 Time: 9:00am (PST), 12:00pm (EST) The clinical lab is a collection of numerous complex workflows. It is imperative that not only specimens are protected from contaminati...
    Speaker: Ryann Rios , Jordan Henderson
    Sponsored By: Labconco
    8
    APR 21, 2021 | 12:00 PM
    Directed evolution - shrinking the haystack with tailor-made synthetic DNA
    Directed evolution - shrinking the haystack with tailor-made synthetic...
    Directed evolution is an effective strategy to optimize the properties of proteins for specific requirements, either for industrial, therapeutics or research applications. As the theoretical...
    Speaker: Dr. Tobias Santl, PhD
    Presented at: Genetics Week Virtual Event Series 2021
    Sponsored By: Thermo Fisher Scientific
    1
    APR 21, 2021 | 10:30 AM
    Panel Presentation: Driving lab efficiency with PCR power
    Panel Presentation: Driving lab efficiency with PCR power
    Detection and/or amplification of target DNA sequences by polymerase chain reaction (PCR) is a prevalent method in molecular biology. PCR has a broad range of applications, including use in...
    Speaker: Kyle Hondorp , Marija Navickaitė
    Presented at: Genetics Week Virtual Event Series 2021
    Sponsored By: Thermo Fisher Scientific
    3
     
     
  • APR 21, 2021 | 12:00 AM
    Saliva - based testing for SARS-CoV-2 diagnosis
    Saliva - based testing for SARS-CoV-2 diagnosis
    Historically, nasopharyngeal sampling has been considered the gold standard for the detection of most upper respiratory tract infections, however major medical and laboratory supply chain is...
    Speaker: Orchid Allicock, PhD
    Presented at: Genetics Week Virtual Event Series 2021
    1
    APR 14, 2021 | 3:00 PM
    NEXTFLEX® Variant-Seq™ SARS-CoV-2 Kit
    NEXTFLEX® Variant-Seq™ SARS-CoV-2 Kit
    As of March 2021, SARS-CoV-2 has infected 115 million people and caused over 2.56 million deaths. The emergence of mutants associated with changes to transmission of SARS-CoV-2 has shown tha...
    Speaker: Pedro Echave, PhD
    Presented at: Coronavirus Series
    Sponsored By: PerkinElmer
    2
    APR 08, 2021 | 11:00 AM
    Pneumonia Diagnosis: Bacterial Superinfection in COVID-19 Patients
    Pneumonia Diagnosis: Bacterial Superinfection in COVID-19 Patients
    Date: April 8, 2021 Time: 11:00am (PDT), 3:00pm (EDT) Pneumonia is a deadly condition with clinical outcomes highly dependent on prompt and appropriate therapy. Diagnosis of pneumonia is cha...
    Speaker: Christian Giske, MD, PhD , Drew Bell, PhD
    Sponsored By: OpGen, Inc.
    18 3
    APR 07, 2021 | 2:15 PM
    Gene Editing Validation with Highly-Accurate HiFi Reads
    Gene Editing Validation with Highly-Accurate HiFi Reads
    In this fireside chat, we’ll discuss how gene editing protocols can benefit from long-read sequencing at various stages to optimize and enhance vector integrity, which cannot be addres...
    Speaker: Michael Weiand , Andrea O'Hara, Ph.D.
    Presented at: Advancing CGT: A GENEWIZ & Brooks Life Sciences Virtual Event
    1
    APR 07, 2021 | 9:00 AM
    Keynote Presentation: Doing more with less - Maximizing Phase Appropriate DOE Strategies
    Keynote Presentation: Doing more with less - Maximizing Phase...
    One challenge pharmaceutical companies face, is moving promising biotherapeutic products into the clinic as fast as safely possible. Devoting the correct amount of time and resources to earl...
    Speaker: Patricia McNeill
    Presented at: Bioprocessing Virtual Event Series 2021
    Sponsored By: Roche Diagnostics
    1
     
     
  • MAR 30, 2021 | 8:00 AM
    Utilizing the Gibco™ CTS™ Rotea™ System, a versatile closed manufacturing system, for cell and gene therapy development
    Utilizing the Gibco™ CTS™ Rotea™ System, a versatile closed manufacturing...
    DATE: March 30, 2021 TIME: 08:00am PST In this talk, we will discuss the value of moving towards modular and automated, closed-system technologies designed to enable scalable and cost-effect...
    Speaker: Mary Ann Santos , Emily Benz , Eric Dubofsky
    Sponsored By: Thermo Fisher Scientific/Gibco
    6
    MAR 30, 2021 | 7:00 AM
    Method optimization of CE-SDS for the next generation of protein biologics
    Method optimization of CE-SDS for the next generation of protein...
    Date: March 30, 2021 Time: 7:00am (PDT), 10:00am (EDT) n this talk today we will discuss how to improve the resolution of your current CE-SDS methods. We will cover how CE-SDS works and what...
    Speaker: Marcus Heinl , Stephen Lock, PhD
    Sponsored By: SCIEX
    8 4
    MAR 24, 2021 | 9:00 AM
    Residual Nucleic Acid Characterization of Cell Culture-Produced Vaccines and Biologics
    Residual Nucleic Acid Characterization of Cell Culture-Produced...
    Date: March 24, 2021 Time: 9:00am (PST), 12:00pm (EST) Determination of residual host cell DNA and RNA are regulatory expectations as they pose potential safety concerns for cell culture-der...
    Speaker: Peter Holper, B.S. Biochemistry and Cell Biology
    Sponsored By: SCIEX
    14
    FEB 24, 2021 | 1:30 PM
    Roundtable Panel Presentation: Recent Trends in Screening GPCRs
    Roundtable Panel Presentation: Recent Trends in Screening GPCRs
    G protein-coupled receptors (GPCRs) are among the most intensively studied drug targets, and account for about ~34% of all drugs approved by the FDA. Examples of drugs targeting GPCRs includ...
    Speaker: Annette Gilchrist, PhD , Professor Kevin Pfleger, MA, PhD, FBPhS , Juan José Fung, PhD , Aarti Kawatkar , Yamina A. Berchiche, PhD , Ajay Yekkirala, PhD
    Presented at: Drug Discovery & Development Virtual Event Series 2021
    1
    FEB 10, 2021 | 12:00 AM
    Refining Pain Management for Laboratory Mice
    Refining Pain Management for Laboratory Mice
    Pain management includes the choice of analgesia agents, their dose, administration method, duration and frequency of treatment, and a pain-monitoring scheme for each individual animal. Insu...
    Speaker: Paulin Jirkof, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2021
    4
     
     
  • FEB 03, 2021 | 12:30 PM
    Optimizing High-Content Imaging of 3D Models for Drug Discovery
    Optimizing High-Content Imaging of 3D Models for Drug Discovery
    In vitro spheroid models are fast becoming the de facto standard for drug discovery applications, largely due to their human-like physiological and morphological characteristics, tissue-like...
    Speaker: Arvonn Tully , Judi Wardwell-Swanson
    Presented at: 7th Annual Conference: SBI2 High Content
    Sponsored By: SBI2, InSphero , Yokogawa
    11 10
    DEC 10, 2020 | 9:00 AM
    Navigate the Pandemic through Laboratory Operational Excellence
    Navigate the Pandemic through Laboratory Operational Excellence
    DATE: December 10, 2020 TIME: 9:00am PST, 12:00pm EST Health systems across the globe continue to be challenged with aging populations, rising chronic diseases and changing care models....
    Speaker: Rouba Trad
    Sponsored By: Abbott Diagnostics
    3
    DEC 10, 2020 | 8:00 AM
    Simple and Fast Charge Variants Analysis of mAbs by CZE
    Simple and Fast Charge Variants Analysis of mAbs by CZE
    Date: December 10, 2020 Time: 8:00am (PST), 11:00am (EST) As you face increasingly shortened timelines to bring new drugs to market, you find yourself strained to finalize analytical methods...
    Speaker: Yan He, Ph.D.
    Sponsored By: SCIEX
    4 1
    DEC 04, 2020 | 5:00 AM
    Hemoglobin A1c: standardization, analytical performance and interference of Hb-variants.
    Hemoglobin A1c: standardization, analytical performance and interference...
    Date: December 04, 2020 Time: 5:00am PDT, 2:00pm CET Diabetes Mellitus has become a worldwide epidemic, affecting approximately 425 million people. Unfortunately, one in two patients remain...
    Speaker: Dr. Erna Lenters-Westra
    Sponsored By: Abbott Diagnostics
    17
    NOV 20, 2020 | 12:00 PM
    The Expanding Role of Microbiology in Antimicrobial Stewardship
    The Expanding Role of Microbiology in Antimicrobial Stewardship
    Date: September 30, 2020 Time: 9:00am (PDT), 12:00pm (EDT) Learning Objectives Why is Stewardship important? What are the core elements of stewardship and microbiology's role Importance...
    Speaker: Margie Morgan, PhD, D(ABMM), MT(ASCP) , Toni Beavers, PhD
    Sponsored By: BD
    14
     
     
  • NOV 12, 2020 | 12:00 AM
    Fully Automated IHC Multiplexing: Techniques and Assay Development
    Fully Automated IHC Multiplexing: Techniques and Assay Development
    Multiplexing IHC is a technique that is increasing in demand as more and more researchers and physicians are being tasked with doing more with less. With multiplexing, you have the advantage...
    Speaker: Mark Hellewell, PhD
    Presented at: DISCOVERY Global User Symposium
    1
    NOV 10, 2020 | 9:00 AM
    Fast and reliable Gene Synthesis for optimized protein expression
    Fast and reliable Gene Synthesis for optimized protein expression
    DATE: November 10, 2020 TIME: 9:00am PT, 12am ET Gene Synthesis ensures fast access to nearly any DNA sequence, regardless its origin or complexity. Its reliability, flexibility and fast tur...
    Speaker: Claudia Chiocchini
    Sponsored By: Thermo Fisher Scientific
    19
    NOV 05, 2020 | 7:00 AM
    Stem cell derived exosome production in stirred-tank bioreactors
    Stem cell derived exosome production in stirred-tank bioreactors
    DATE: Date needed, 2020 TIME: Time needed Exosomes are a population of naturally occurring mobile, membrane-limited, 30 – 100 nm in diameter, extracellular vesicles containing a large...
    Speaker: Jorge Escobar , Aurélie Tacheny
    Presented at: Eppendorf Planet of Knowledge - A New Dimension
    Sponsored By: Eppendorf
    12
    OCT 22, 2020 | 8:00 AM
    Driving lab efficiency with PCR power
    Driving lab efficiency with PCR power
    Abstract: Detection and/or amplification of target DNA sequences by polymerase chain reaction (PCR) is a prevalent method in molecular biology. PCR has a broad range of applications, includi...
    Speaker: Kyle Hondorp , Marija Navickaitė
    Sponsored By: Thermo Fisher Scientific
    150 2
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