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    Methylome

    5-Methylcytosine (5mC) is the methylated form of cystine, one of the four bases which makes up DNA. The total distribution of 5mC in the genome is defined as the methylome. Because patterns of methylation are often disrupted in disease pathology, the methylome can be used for therapeutic development.

    Webinars

    • MAY 19, 2022 | 8:00 AM
      Automated sample preparation for reproducible clinical proteomics
      Automated sample preparation for reproducible clinical proteomics
      Date: May 19, 2022 Time: 8:00am (PDT), 11:00pm (EDT), 5:00pm (CEST) Mass spectrometry (MS)-based proteomic technologies are increasingly applied in a clinical context for disease classific...
      Speaker: Jeroen Krijgsveld , Nicolas Autret, PhD , Ignasi Forné, PhD
      Sponsored By: Covaris, Inc.
      14
      SEP 09, 2021 | 12:00 AM
      RNA Viruses Reshape the RNA Modification Landscape in the Cell
      RNA Viruses Reshape the RNA Modification Landscape in the Cell
      Ribonucleic acid (RNA) has a breathtaking variety of biological functions, which far exceeds its classical role as a carrier of genetic information. The repertoire of this versatile molecule...
      Speaker: Cara T. Pager, PhD
      Presented at: Microbiology Week Virtual Event Series 2021
      1
      SEP 09, 2020 | 12:00 AM
      Bacterial Epigenomes: Technology, Pathogens and Microbiome
      Bacterial Epigenomes: Technology, Pathogens and Microbiome
      Prokaryotic DNA contains three types of methylation: N6-methyladenine, N4-methylcytosine and 5-methylcytosine. The lack of tools to analyse the frequency and distribution of methylated resid...
      Speaker: Gang Fang
      Presented at: Microbiology Week Virtual Event Series 2020
      4
      APR 15, 2020 | 9:00 AM
      Single-cell multi-omics: DNA methylation and 3D genome
      Single-cell multi-omics: DNA methylation and 3D genome
      DATE: April 15, 2020 TIME: 9:00am PT, 12:00pm ET We report a molecular assay, Methyl-HiC, that can simultaneously capture the chromosome conformation and DNA methylome in a cell. Methyl-HiC...
      Speaker: Yaping Liu, Ph.D.
      Sponsored By: Zymo Research
      9 3
      APR 25, 2019 | 12:00 PM
      Diagnosis and Treatment of Tuberculosis, a Case Study in Challenges and Threats Posed by Infectious Diseases
      Diagnosis and Treatment of Tuberculosis, a Case Study in Challenges...
      Tuberculosis has killed more than one billion people in the last 200 years. It is the oldest and the deadliest human pathogen, recently surpassing HIV. Its adaptation to host and drug pressur...
      Speaker: Faramarz Valafar, PhD
      Presented at: Infectious Disease Virtual Event Series 2019
      2
      NOV 09, 2017 | 2:00 AM
      Mammalian DNA methylation landscapes and human cancers
      Mammalian DNA methylation landscapes and human cancers
      Concerted efforts over past decades have established a thorough understanding of the canonical somatic DNA methylation landscape as well as its systematic misregulation across many cancers. H...
      Speaker: Alexander Meissner
      Presented at: 5th annual 24 Hours of Stem Cells™ virtual event
      2
      FEB 22, 2017 | 6:00 AM
      Mate-pair next generation sequencing as a powerful clinical tool for the characterization of cancer
      Mate-pair next generation sequencing as a powerful clinical tool...
      Recent advances in DNA sequencing have now made it possible to characterize genomes, transcriptomes and even methylomes which is transforming both basic research and clinical practice. Whole...
      Speaker: David Smith, PhD
      Presented at: Precision Medicine Virtual Event Series 2017
      4
    MAY 19, 2022 | 8:00 AM
    Automated sample preparation for reproducible clinical proteomics
    Automated sample preparation for reproducible clinical proteomics
    Date: May 19, 2022 Time: 8:00am (PDT), 11:00pm (EDT), 5:00pm (CEST) Mass spectrometry (MS)-based proteomic technologies are increasingly applied in a clinical context for disease classific...
    Speaker: Jeroen Krijgsveld , Nicolas Autret, PhD , Ignasi Forné, PhD
    Sponsored By: Covaris, Inc.
    14
    SEP 09, 2021 | 12:00 AM
    RNA Viruses Reshape the RNA Modification Landscape in the Cell
    RNA Viruses Reshape the RNA Modification Landscape in the Cell
    Ribonucleic acid (RNA) has a breathtaking variety of biological functions, which far exceeds its classical role as a carrier of genetic information. The repertoire of this versatile molecule...
    Speaker: Cara T. Pager, PhD
    Presented at: Microbiology Week Virtual Event Series 2021
    1
    SEP 09, 2020 | 12:00 AM
    Bacterial Epigenomes: Technology, Pathogens and Microbiome
    Bacterial Epigenomes: Technology, Pathogens and Microbiome
    Prokaryotic DNA contains three types of methylation: N6-methyladenine, N4-methylcytosine and 5-methylcytosine. The lack of tools to analyse the frequency and distribution of methylated resid...
    Speaker: Gang Fang
    Presented at: Microbiology Week Virtual Event Series 2020
    4
    APR 15, 2020 | 9:00 AM
    Single-cell multi-omics: DNA methylation and 3D genome
    Single-cell multi-omics: DNA methylation and 3D genome
    DATE: April 15, 2020 TIME: 9:00am PT, 12:00pm ET We report a molecular assay, Methyl-HiC, that can simultaneously capture the chromosome conformation and DNA methylome in a cell. Methyl-HiC...
    Speaker: Yaping Liu, Ph.D.
    Sponsored By: Zymo Research
    9 3
    APR 25, 2019 | 12:00 PM
    Diagnosis and Treatment of Tuberculosis, a Case Study in Challenges and Threats Posed by Infectious Diseases
    Diagnosis and Treatment of Tuberculosis, a Case Study in Challenges...
    Tuberculosis has killed more than one billion people in the last 200 years. It is the oldest and the deadliest human pathogen, recently surpassing HIV. Its adaptation to host and drug pressur...
    Speaker: Faramarz Valafar, PhD
    Presented at: Infectious Disease Virtual Event Series 2019
    2
     
     
  • NOV 09, 2017 | 2:00 AM
    Mammalian DNA methylation landscapes and human cancers
    Mammalian DNA methylation landscapes and human cancers
    Concerted efforts over past decades have established a thorough understanding of the canonical somatic DNA methylation landscape as well as its systematic misregulation across many cancers. H...
    Speaker: Alexander Meissner
    Presented at: 5th annual 24 Hours of Stem Cells™ virtual event
    2
    FEB 22, 2017 | 6:00 AM
    Mate-pair next generation sequencing as a powerful clinical tool for the characterization of cancer
    Mate-pair next generation sequencing as a powerful clinical tool...
    Recent advances in DNA sequencing have now made it possible to characterize genomes, transcriptomes and even methylomes which is transforming both basic research and clinical practice. Whole...
    Speaker: David Smith, PhD
    Presented at: Precision Medicine Virtual Event Series 2017
    4
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