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    Phenotypic Screening

    Phenotypic Screening: is a type of screening that is used in biological research and drug discovery which is utilized to identify substances like molecules, peptides for RNAi that can change the phenotype of a cell or an organism. Phenotypic screening has been highly employed in the discovery of new drugs.

    Trending News

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      Genetics & Genomics
      Brain Organoids Reveal Cell-Specific Developmental Defects in Autism
      Brain Organoids Reveal Cell-Specific Developmental Defects in Autism
      A human brain organoid mosaic, created with a new tool called CHOOSE (CRISPR-human organoids-scRNA-seq) in this image - ...
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      5 1
      JUL 17, 2023
      Drug Discovery & Development
      Functional Characterization of Monoclonal Antibodies Using Kinetic Live-Cell Analysis
      Input your information to
      to access this free gated article
      Functional Characterization of Monoclonal Antibodies Using Kinetic Live-Cell Analysis
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      Sponsored By: Sartorius
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      Health & Medicine
      New Male Contraception Boasts 2.5 Hours of Infertility
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      SEP 22, 2022
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      Human Protein Crucial to Infection & Disease is Discovered
      Human Protein Crucial to Infection & Disease is Discovered
      The pandemic virus SARS-CoV-2 caused many scientists to begin studying infectious disease, in search of ways to stop the ...
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      JUN 13, 2022
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      MAR 22, 2022
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      Rare genetic disorders occur, defined as diseases that affect less than 200,000 Americans, occur in about 6% o ...
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      DEC 29, 2021
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      Drug discovery and development for treating river blindness
      Drug discovery and development for treating river blindness
      Onchocerciasis, also known as river blindness, is a parasitic disease caused by the filarial nematode Onchocerca vo ...
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      DEC 12, 2021
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      Cyagen: One-Stop Research Model & Gene Therapy Solutions
      Cyagen: One-Stop Research Model & Gene Therapy Solutions
      With gene therapy demonstrating an enormous potential to treat a wide range of diseases, Cyagen has added a range of gen ...
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      OCT 06, 2021
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      AUG 05, 2021
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      A Smartphone App that Identifies Disease-Carrying, Insecticide-Resistant Mosquitos.
      A Smartphone App that Identifies Disease-Carrying, Insecticide-Resistant Mosquitos.
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      Written By: J. Bryce Ortiz
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      MAY 19, 2021
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      NOV 09, 2019
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      SEP 07, 2019
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      DEC 30, 2018
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      An Improved Alzheimer's Model Adds Genetic Diversity
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      DEC 15, 2018
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      Neanderthal Genes Provide Insight Into Human Brain Evolution
      Neanderthal Genes Provide Insight Into Human Brain Evolution
      Neanderthal heads are almost football-shaped, while modern humans have much rounder brains and skulls.
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      OCT 11, 2018
      Chemistry & Physics
      Nobel Chemistry Prize Winners Brought Artifical Selection Into Chemistry
      Nobel Chemistry Prize Winners Brought Artifical Selection Into Chemistry
      Last Wednesday, Oct 3rd, the Royal Swedish Academy of Sciences announced the winners of 2018 Nobel Prize in Chemistry: F ...
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      MAY 21, 2018
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      Epigenetics is defined and outlined as important in gene expression and a possible cause for cancer development & as a t ...
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      APR 24, 2018
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      Methods Used in Drug Discovery and Development
      The method of choice in drug-discovery in the past two decades has been target-based screening. Now, phenotypic screenin ...
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      2
      APR 24, 2018
      Cancer
      Synthetic Retinoid Shows Promise for Inhibition of Cancer Cells
      Synthetic Retinoid Shows Promise for Inhibition of Cancer Cells
      Researchers studied the potential use of a synthetic retinoid, WYC-209, as an inhibitor of cancer cell growth and metast ...
      Written By: Mauri Brueggeman
      2
      JAN 23, 2018
      Clinical & Molecular DX
      Unique Epigenetic Signatures Diagnose Rare Disorders
      Unique Epigenetic Signatures Diagnose Rare Disorders
      Epigenetic changes impact gene activity without actually altering the sequence of DNA, and scientists are now able to di ...
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      DEC 27, 2017
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    NOV 29, 2023
    Cancer
    CAR-T Revolution: Developing T Cells into Cancer Assassins
    CAR-T Revolution: Developing T Cells into Cancer Assassins
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    Sponsored By: Sartorius
    5
    SEP 13, 2023
    Genetics & Genomics
    Brain Organoids Reveal Cell-Specific Developmental Defects in Autism
    Brain Organoids Reveal Cell-Specific Developmental Defects in Autism
    A human brain organoid mosaic, created with a new tool called CHOOSE (CRISPR-human organoids-scRNA-seq) in this image - ...
    Written By: Carmen Leitch
    5 1
    JUL 17, 2023
    Drug Discovery & Development
    Functional Characterization of Monoclonal Antibodies Using Kinetic Live-Cell Analysis
    Input your information to
    to access this free gated article
    Functional Characterization of Monoclonal Antibodies Using Kinetic Live-Cell Analysis
    Introduction Antibodies are the ideal therapeutic biomolecules due to their ability to bind to a variety of targets with ...
    Sponsored By: Sartorius
    5
    FEB 14, 2023
    Health & Medicine
    New Male Contraception Boasts 2.5 Hours of Infertility
    New Male Contraception Boasts 2.5 Hours of Infertility
    If this proof-of-concept pans out, a single oral or injection of their inhibitor will block sperm mobility for up to 2.5 ...
    Written By: Amielle Moreno
    3
    OCT 23, 2022
    Neuroscience
    The Neurobiology of Impulsivity in Children
    The Neurobiology of Impulsivity in Children
    McGill University researchers have developed a genetically based score to identify young children who are at risk of imp ...
    Written By: Kerry Charron
    1
     
     
  • SEP 22, 2022
    Cell & Molecular Biology
    Human Protein Crucial to Infection & Disease is Discovered
    Human Protein Crucial to Infection & Disease is Discovered
    The pandemic virus SARS-CoV-2 caused many scientists to begin studying infectious disease, in search of ways to stop the ...
    Written By: Carmen Leitch
    3
    JUN 13, 2022
    Microbiology
    Fight Antimicrobial Resistance
    Fight Antimicrobial Resistance
    Carbapenem antibiotics are one of the few remaining antibiotics effective in treating ESBL infections or MDRO. Howe ...
    Sponsored By: Hardy Diagnostics Le
    4
    MAR 22, 2022
    Clinical & Molecular DX
    Artificial Intelligence Diagnoses Rare Diseases By Examining Facial Features
    Artificial Intelligence Diagnoses Rare Diseases By Examining Facial Features
    Rare genetic disorders occur, defined as diseases that affect less than 200,000 Americans, occur in about 6% o ...
    Written By: Katie Kokolus
    3
    DEC 29, 2021
    Drug Discovery & Development
    Drug discovery and development for treating river blindness
    Drug discovery and development for treating river blindness
    Onchocerciasis, also known as river blindness, is a parasitic disease caused by the filarial nematode Onchocerca vo ...
    Written By: J. Bryce Ortiz
    1
    DEC 12, 2021
    Drug Discovery & Development
    Cyagen: One-Stop Research Model & Gene Therapy Solutions
    Cyagen: One-Stop Research Model & Gene Therapy Solutions
    With gene therapy demonstrating an enormous potential to treat a wide range of diseases, Cyagen has added a range of gen ...
    Sponsored By: Cyagen Le
    1
     
     
  • OCT 06, 2021
    Genetics & Genomics
    Signs of Huntington's Disease in Early Embryonic Development
    Signs of Huntington's Disease in Early Embryonic Development
    Huntington's disease is a neurodegenerative disorder that's caused by mutations in the huntingtin gene. People can be di ...
    Written By: Carmen Leitch
    1
    AUG 05, 2021
    Drug Discovery & Development
    A Smartphone App that Identifies Disease-Carrying, Insecticide-Resistant Mosquitos.
    A Smartphone App that Identifies Disease-Carrying, Insecticide-Resistant Mosquitos.
    Mosquito-borne diseases can lead to serious disability or death. These diseases, which include Malaria, Zika, West Nile ...
    Written By: J. Bryce Ortiz
    1
    MAY 19, 2021
    Immunology
    Intestinal Macrophages Promote Chronic Inflammation in Obesity
    Intestinal Macrophages Promote Chronic Inflammation in Obesity
    A research group from Switzerland hypothesized that immune cells in the gut (gastrointestinal tract) must trigger chroni ...
    Written By: Caroline Wallace
    2
    APR 04, 2020
    Cancer
    Unique Cancer Mutation Hijacks Nearby Signaling Pathway
    Unique Cancer Mutation Hijacks Nearby Signaling Pathway
      In cancer, tyrosine kinase mutations are quite common. MET is one such example that normally binds its native lig ...
    Written By: Jasper Cantrell
    1
    NOV 09, 2019
    Cancer
    Using machine learning to discover new cancer treatments
    Using machine learning to discover new cancer treatments
    Flashback fifty years ago and many of the modern world’s inventions and discoveries would have been undreamed of & ...
    Written By: Kathryn DeMuth Sullivan
    2 3
     
     
  • SEP 07, 2019
    Genetics & Genomics
    Depression Can Cause Many Different Diseases
    Depression Can Cause Many Different Diseases
    Major depressive disorder is a serious public health problem, thought to affect around seven percent of American adults ...
    Written By: Carmen Leitch
    1
    DEC 30, 2018
    Genetics & Genomics
    An Improved Alzheimer's Model Adds Genetic Diversity
    An Improved Alzheimer's Model Adds Genetic Diversity
    Researchers created a mouse model of Alzheimer's disease that has more in common with the human disease than current mod ...
    Written By: Carmen Leitch
    1
    DEC 15, 2018
    Genetics & Genomics
    Neanderthal Genes Provide Insight Into Human Brain Evolution
    Neanderthal Genes Provide Insight Into Human Brain Evolution
    Neanderthal heads are almost football-shaped, while modern humans have much rounder brains and skulls.
    Written By: Carmen Leitch
    1
    OCT 11, 2018
    Chemistry & Physics
    Nobel Chemistry Prize Winners Brought Artifical Selection Into Chemistry
    Nobel Chemistry Prize Winners Brought Artifical Selection Into Chemistry
    Last Wednesday, Oct 3rd, the Royal Swedish Academy of Sciences announced the winners of 2018 Nobel Prize in Chemistry: F ...
    Written By: Daniel Duan
    1
    MAY 21, 2018
    Cancer
    Epigenetics & Cancer: DNA Modification Impacts
    Epigenetics & Cancer: DNA Modification Impacts
    Epigenetics is defined and outlined as important in gene expression and a possible cause for cancer development & as a t ...
    Written By: Mauri Brueggeman
    3
     
     
  • APR 24, 2018
    Drug Discovery & Development
    Methods Used in Drug Discovery and Development
    Methods Used in Drug Discovery and Development
    The method of choice in drug-discovery in the past two decades has been target-based screening. Now, phenotypic screenin ...
    Written By: Nouran Amin
    2
    APR 24, 2018
    Cancer
    Synthetic Retinoid Shows Promise for Inhibition of Cancer Cells
    Synthetic Retinoid Shows Promise for Inhibition of Cancer Cells
    Researchers studied the potential use of a synthetic retinoid, WYC-209, as an inhibitor of cancer cell growth and metast ...
    Written By: Mauri Brueggeman
    2
    JAN 23, 2018
    Clinical & Molecular DX
    Unique Epigenetic Signatures Diagnose Rare Disorders
    Unique Epigenetic Signatures Diagnose Rare Disorders
    Epigenetic changes impact gene activity without actually altering the sequence of DNA, and scientists are now able to di ...
    Written By: Kara Marker
    4
    DEC 27, 2017
    Drug Discovery & Development
    Tools, Probes, and Drug Compounds
    Tools, Probes, and Drug Compounds
    various medicine chemistry tools
    Written By: Courtney Schaal
    1
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