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    Rett Syndrome

    Rett syndrome: is a genetic brain disorder which typically becomes apparent after 6 to 18 months of age in females. Symptoms include problems with language, coordination, and repetitive movements. Often there is slower growth, problems walking, and a smaller head size.

    Webinars

    • MAR 27, 2019 | 10:30 AM
      Panel Discussion: The Benefits and Challenges of Cannabis in Pediatric Conditions in Legal States
      Panel Discussion: The Benefits and Challenges of Cannabis in Pediatric...
      In this panel discussion, parents of medically compromised children using cannabis discuss their experiences of what led them to start cannabis therapy, what delivery methods they currently u...
      Speaker: Kenton Crowley, Pharm. D., FAARFM, ABAAHP , Janelle Donovan , Herah Osborne , Dawn Wells
      Presented at: Cannabis Sciences Virtual Event Series 2019
      1
      FEB 13, 2019 | 1:30 PM
      Precision Medicine for Mice: Digital Biomarkers Transforming Drug Discovery
      Precision Medicine for Mice: Digital Biomarkers Transforming Drug...
      Preclinical drug discovery is at the edge of a major transformation that promises to improve translation to the clinic through enhanced acquisition and advanced analysis of data. While an imp...
      Speaker: Laura Schaevitz, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2019
      5
      JUN 26, 2018 | 9:00 AM
      Automated In Vivo Efficacy Assessment in Preclinical Lung Disease Models
      Automated In Vivo Efficacy Assessment in Preclinical Lung Disease...
      Treatments for respiratory diseases represent an enormous, unmet medical need with limited therapies currently approved for use. Despite many compounds demonstrating beneficial effects in ani...
      Speaker: Laura Schaevitz, PhD
      Sponsored By: Vium
      6
      APR 17, 2018 | 8:00 AM
      StemoniX microBrain 3D Assay Ready Plates as a Human iPSC-based Neural Spheroid Platform for  High Throughput Drug Screening
      StemoniX microBrain 3D Assay Ready Plates as a Human iPSC-based...
      DATE: April 17, 2018TIME: 8:00AM PST, 11:00AM ESTRecently, much research has focused on obtaining 3D brain organoids in an attempt to better recapitulate brain development and function...
      Speaker: Cassiano Carromeu, PhD , Grischa Chandy, PhD , Oksana Sirenko, PhD
      Sponsored By: Molecular Devices
      7 1
      FEB 21, 2018 | 12:00 PM
      Allosteric Modulation of Metabotropic Glutamate Receptors for the Treatment of Neurodevelopmental Disorders
      Allosteric Modulation of Metabotropic Glutamate Receptors for...
      Rett syndrome (RTT) is a neurodevelopmental disorder caused by mutations in the Methyl CpG Binding Protein 2 (MECP2) gene. In mouse models of RTT, deficits in long-term potentiation (LTP) at...
      Speaker: Colleen Niswender, PhD
      Presented at: Drug Discovery Virtual Event Series 2018
      1
      FEB 08, 2018 | 7:30 AM
      Modernization of Animal Studies
      Modernization of Animal Studies
      There is a growing debate about the usefulness of animal studies in biomedical research and drug development. Some of the challenges in translation from animals to human patients may be from...
      Speaker: Natalie Bratcher , Sean Maguire, VMD, MS, DACLAM , Laura Schaevitz, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2018
      2
      FEB 08, 2017 | 10:30 AM
      Obtaining non-invasive readouts and early safety signals from rodent models
      Obtaining non-invasive readouts and early safety signals from...
      DATE: February 8, 2017TIME: 10:30am PT, 1:30pm ETThe utility of animal models in drug development is limited, in part, by the measures available to researchers for monitoring animals. I...
      Speaker: Laura Schaevitz, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2017
      3
    MAR 27, 2019 | 10:30 AM
    Panel Discussion: The Benefits and Challenges of Cannabis in Pediatric Conditions in Legal States
    Panel Discussion: The Benefits and Challenges of Cannabis in Pediatric...
    In this panel discussion, parents of medically compromised children using cannabis discuss their experiences of what led them to start cannabis therapy, what delivery methods they currently u...
    Speaker: Kenton Crowley, Pharm. D., FAARFM, ABAAHP , Janelle Donovan , Herah Osborne , Dawn Wells
    Presented at: Cannabis Sciences Virtual Event Series 2019
    1
    FEB 13, 2019 | 1:30 PM
    Precision Medicine for Mice: Digital Biomarkers Transforming Drug Discovery
    Precision Medicine for Mice: Digital Biomarkers Transforming Drug...
    Preclinical drug discovery is at the edge of a major transformation that promises to improve translation to the clinic through enhanced acquisition and advanced analysis of data. While an imp...
    Speaker: Laura Schaevitz, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2019
    5
    JUN 26, 2018 | 9:00 AM
    Automated In Vivo Efficacy Assessment in Preclinical Lung Disease Models
    Automated In Vivo Efficacy Assessment in Preclinical Lung Disease...
    Treatments for respiratory diseases represent an enormous, unmet medical need with limited therapies currently approved for use. Despite many compounds demonstrating beneficial effects in ani...
    Speaker: Laura Schaevitz, PhD
    Sponsored By: Vium
    6
    APR 17, 2018 | 8:00 AM
    StemoniX microBrain 3D Assay Ready Plates as a Human iPSC-based Neural Spheroid Platform for  High Throughput Drug Screening
    StemoniX microBrain 3D Assay Ready Plates as a Human iPSC-based...
    DATE: April 17, 2018TIME: 8:00AM PST, 11:00AM ESTRecently, much research has focused on obtaining 3D brain organoids in an attempt to better recapitulate brain development and function...
    Speaker: Cassiano Carromeu, PhD , Grischa Chandy, PhD , Oksana Sirenko, PhD
    Sponsored By: Molecular Devices
    7 1
    FEB 21, 2018 | 12:00 PM
    Allosteric Modulation of Metabotropic Glutamate Receptors for the Treatment of Neurodevelopmental Disorders
    Allosteric Modulation of Metabotropic Glutamate Receptors for...
    Rett syndrome (RTT) is a neurodevelopmental disorder caused by mutations in the Methyl CpG Binding Protein 2 (MECP2) gene. In mouse models of RTT, deficits in long-term potentiation (LTP) at...
    Speaker: Colleen Niswender, PhD
    Presented at: Drug Discovery Virtual Event Series 2018
    1
     
     
  • FEB 08, 2018 | 7:30 AM
    Modernization of Animal Studies
    Modernization of Animal Studies
    There is a growing debate about the usefulness of animal studies in biomedical research and drug development. Some of the challenges in translation from animals to human patients may be from...
    Speaker: Natalie Bratcher , Sean Maguire, VMD, MS, DACLAM , Laura Schaevitz, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2018
    2
    FEB 08, 2017 | 10:30 AM
    Obtaining non-invasive readouts and early safety signals from rodent models
    Obtaining non-invasive readouts and early safety signals from...
    DATE: February 8, 2017TIME: 10:30am PT, 1:30pm ETThe utility of animal models in drug development is limited, in part, by the measures available to researchers for monitoring animals. I...
    Speaker: Laura Schaevitz, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2017
    3
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