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T cell repertoire
T cell receptors (TCRs) are proteins on the surface of T cells which recognize foreign antigen attached to major histocompatibility complex (MHC) molecules and initiating a immune response. TCRs undergo genetic rearrangements allowing each to recognize a single antigen and the unique genetic combinations are called the T cell repertoire. The more unique TCRs present in a system, the more robust the immune potential.
What's Popular in T cell repertoire
OCT 07, 2021 | 11:55 PM
Summary: Cancer neoantigens are highly specific to the tumor, potently immunogenic and can be targeted by both vaccines and engineered cellular therapies. This talk will introduce the defini...
SEP 09, 2021 | 12:00 AM
Ribonucleic acid (RNA) has a breathtaking variety of biological functions, which far exceeds its classical role as a carrier of genetic information. The repertoire of this versatile molecule...
JUN 02, 2021 | 3:00 PM
PD-L1 is a key inhibitor of T cell activation that is often over-expressed in cancer to escape immune surveillance and promote tumor progression. Blocking antibodies against PD-L1 or its rec...
SEP 17, 2020 | 4:30 PM
T cells are the adaptive immune system’s first responders to any virus, circulating in the blood to detect and quickly multiply to attack the virus, and also support the development of...
JUN 02, 2021 | 3:00 PM
PD-L1 is a key inhibitor of T cell activation that is often over-expressed in cancer to escape immune surveillance and promote tumor progression. Blocking antibodies against PD-L1 or its rec...
SEP 17, 2020 | 4:30 PM
T cells are the adaptive immune system’s first responders to any virus, circulating in the blood to detect and quickly multiply to attack the virus, and also support the development of...
