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    Translation

    During translation, cells 'read' genetic information in the form of messenger RNA and use this as a blueprint to synthesize proteins. Translation occurs continuously in living cells and is executed by organelles called ribosomes.

    Webinars

    • AUG 21, 2014 | 12:45 PM
      Predictive and not: understanding the mixed messages of our DNA
      Predictive and not: understanding the mixed messages of our DNA
      When whole genome and whole exome sequencing are introduced into health care, and offered directly to consumers in commercial settings, the landscape of genetic testing will drastically chang...
      Speaker: Cecile Janssens, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2014
      36
      AUG 21, 2014 | 11:30 AM
      Understanding the Genetics of Common Disease:  Using Big Data approaches to see the emergent whole
      Understanding the Genetics of Common Disease: Using Big Data...
      The comprehensive, multidimensional molecular characterization of tumors and the individuals in which they have developed is transforming cancer definition, diagnosis, treatment, and preventi...
      Speaker: Kenneth Buetow, PhD, FACMI
      Presented at: Genetics and Genomics Virtual Event Series 2014
      198
      AUG 21, 2014 | 9:45 AM
      Pathway based analyses for genetic susceptibility to cancer and autoimmune disease
      Pathway based analyses for genetic susceptibility to cancer and...
      In this presentation I describe pathway based analyses of genotyping data to identify pathways related to the development of complex diseases, with a focus on lung cancer and selected autoimm...
      Speaker: Christopher I Amos, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2014
      62
      AUG 21, 2014 | 8:45 AM
      From Genetics to Genetic Medicine: Gene Therapy for vision restoration as a case study
      From Genetics to Genetic Medicine: Gene Therapy for vision restoration...
      Gene therapy for two forms of inherited retinal degeneration have met promising safety and efficacy endpoints in early stage clinical trials. These approaches made use of a replication defect...
      Speaker: Luk H Vandenberghe, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2014
      0
      AUG 20, 2014 | 11:45 AM
      Ethical, Legal and Social Issues of Direct-to-Consumer Genetic Testing
      Ethical, Legal and Social Issues of Direct-to-Consumer Genetic...
      Direct-to-consumer (DTC) genetic testing can be understood as including two related aspects: first, the advertising of genetic tests directly to consumers; and second, the direct access or or...
      Speaker: Heidi C Howard, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2014
      25
      AUG 20, 2014 | 10:45 AM
      OncoScan Assay for copy number from FFPE. Publications & cases on actionable CNV detection
      OncoScan Assay for copy number from FFPE. Publications & cases...
      A recent publication in Nature Genetics1 analyzed TCGA data, and classified solid tumors into two mutually exclusive classes: C class tumors, driven by copy number alterations; and M class tu...
      Speaker: Padma Sundar, MBA, MPH
      Presented at: Genetics and Genomics Virtual Event Series 2014
      14
      AUG 20, 2014 | 8:30 AM
      Actionable mutation detection with multiplex pcr-based targeted enrichment approach for next generation sequencing (NGS)
      Actionable mutation detection with multiplex pcr-based targeted...
      Next-generation sequencing (NGS) has revolutionized extraction of genomic information, facilitating rapid advances in the fields of clinical research and molecular diagnostics. However, c...
      Speaker: Vikram Devgan, PhD, MBA
      Presented at: Genetics and Genomics Virtual Event Series 2014
      16
      MAY 30, 2014 | 9:00 AM
      Panel Discussion: Vaginitis/vaginosis: Diagnosis and workup using conventional and molecular tests. Dr's Bowman and Wang
      Panel Discussion: Vaginitis/vaginosis: Diagnosis and workup using...
      Vaginitis and vaginosis, including Bacterial Vaginosis (BV), Vulvovaginal Candidiasis (VVC), and Trichomoniasis (TV), are extremely common conditions, consuming many healthcare resources and...
      Speaker: Cynthia Foss Bowman, MD and Guiqing Wang, MD, PhD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2014
      79
      MAY 30, 2014 | 7:30 AM
      Multiplexed Fusion Gene Detection using Next Generation Sequencing
      Multiplexed Fusion Gene Detection using Next Generation Sequencing
      As next-generation sequencing (NGS) platforms advance in their speed, ease-of-use, and cost-effectiveness, many translational researchers are transitioning from microarrays to RNA sequencing...
      Speaker: Kelli Bramlett and Jeoffrey Schageman
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2014
      82
      MAY 29, 2014 | 12:00 PM
      Pharmacogenomics and Pharmacometabolomics for Personalized Medicine
      Pharmacogenomics and Pharmacometabolomics for Personalized Medicine
      Pharmcogenomics (PGx) is the 2nd potential clinical application of genomic medicine, preceded by genomic application for cancer. In the recently published, 2012 Institute of Medicine report o...
      Speaker: Steven Wong, PhD, DABCC(TC), FACB
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2014
      36
      MAY 29, 2014 | 10:30 AM
      Adding Value in Healthcare Delivery: Uses for Clinical Laboratory Informatics in Decision Support
      Adding Value in Healthcare Delivery: Uses for Clinical Laboratory...
      Clinical laboratory information provides decision support for most healthcare providers and impacts care processes and patient outcomes throughout the entire health services delivery system....
      Speaker: Elizabeth Kenimer Leibach, EdD, MS, MLS(ASCP), SBB
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2014
      70
      MAY 29, 2014 | 7:30 AM
      Identification of predictive biomarkers from high throughput drug combination screening data
      Identification of predictive biomarkers from high throughput drug...
      One of the major challenges to oncology based drug discovery and development has been the limited or incremental impact that many targeted agents have exhibited in the clinic. Understanding a...
      Speaker: Emma Bowden, PhD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2014
      20
      MAY 28, 2014 | 9:00 AM
      Keynote: Establishing an economic BRCA1 and BRCA2 (BRCA) gene analyses research workflow using custom AmpliSeq panel design and the Ion PGM System
      Keynote: Establishing an economic BRCA1 and BRCA2 (BRCA) gene...
      While the "Jolie effect" has refocused attention on the central role of BRCA gene analyses in the diagnosis and prevention of hereditary breast and ovarian cancer, there is a global disparity...
      Speaker: Jeffrey N Weitzel, MD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2014
      9
      MAR 20, 2014 | 2:00 PM
      Cross-talk & Developmental Programs A Key to Translational Stem Cell Biology
      Cross-talk & Developmental Programs A Key to Translational...
      The therapeutic utility of stem cells is rooted in an understanding -- and exploitation -- of their natural role from earliest development to lifes end. Their job is first to participate in o...
      Speaker: Evan W. Snyder, M.D., Ph.D., F.A.A.P
      Presented at: Neuroscience Virtual Event Series 2014
      94
      MAR 20, 2014 | 1:00 PM
      The role of high throughput sequencing in the research and diagnosis of neurodegenerative disorders
      The role of high throughput sequencing in the research and diagnosis...
      Using high throughput next-generation sequencing to simultaneously search large number of genes for pathogenic mutations has numerous advantages. It decreases the pressure to narrow the dif...
      Speaker: Peter L Nagy, MD, PhD
      Presented at: Neuroscience Virtual Event Series 2014
      0
      MAR 20, 2014 | 12:00 PM
      Axonal Protein Synthesis in Neurodevelopment and -degeneration
      Axonal Protein Synthesis in Neurodevelopment and -degeneration
      Spatially restricted protein synthesis is an important mechanism for the development and maintenance of many morphologically polarized cells including neurons. While most proteins are synthes...
      Speaker: Ulrich Hengst, PhD
      Presented at: Neuroscience Virtual Event Series 2014
      84
      MAR 20, 2014 | 10:00 AM
      Neuroeconomy; Economic Impact of Neurodegenerative Diseases both in the US and Globally
      Neuroeconomy; Economic Impact of Neurodegenerative Diseases both...
      When speaking of neurodegenerative diseases, average public is not made aware of the true cost that brain related disorders have on annual budget. The true impact on economy is not usually...
      Speaker: Lana Morrow, PhD
      Presented at: Neuroscience Virtual Event Series 2014
      48
      MAR 20, 2014 | 8:00 AM
      Cross-talk & Developmental Programs A Key to Translational Stem Cell Biology
      Cross-talk & Developmental Programs A Key to Translational Stem...
      The therapeutic utility of stem cells is rooted in an understanding -- and exploitation -- of their natural role from earliest development to lifes end. Their job is first to participate in o...
      Speaker: Evan W. Snyder, M.D., Ph.D., F.A.A.P
      Presented at: Beckman Coulter Life Sciences Virtual Trade Show
      Sponsored By: Beckman Coulter Life Sciences, Beckman Coulter Life Sciences
      1
      MAR 20, 2014 | 7:00 AM
      Huntingtons Disease: Twenty years and counting
      Huntingtons Disease: Twenty years and counting
      Huntington's disease (HD) is a progressive, inherited, degenerative brain disorder that produces physical, mental and emotional changes. Named for George Huntington, the physician who fi...
      Speaker: Margaret Sutherland, PhD
      Presented at: Neuroscience Virtual Event Series 2014
      106
      MAR 19, 2014 | 11:00 AM
      When good neurons go bad: Dopamine neuron regulation and its disruption in schizophrenia and depression
      When good neurons go bad: Dopamine neuron regulation and its disruption...
      ...
      Speaker: Anthony Grace, PhD
      Presented at: Neuroscience Virtual Event Series 2014
      36
      MAR 19, 2014 | 10:00 AM
      MS Bioscreen: From the Bedside to the Bench and Back
      MS Bioscreen: From the Bedside to the Bench and Back
      We present a personalized medicine suite of software applications developed at UCSF for multiple sclerosis (MS): the MS Bioscreen. This new tool addresses the challenges of the dynamic manage...
      Speaker: Pierre-Antoine Gourraud, PhD, MPH
      Presented at: Neuroscience Virtual Event Series 2014
      25
      MAR 19, 2014 | 9:00 AM
      Brain Computer Interfaces: Neurotech in the Future of Neuroscience
      Brain Computer Interfaces: Neurotech in the Future of Neuroscience
      When speaking of neurodegenerative diseases, average public is not made aware of the true cost that brain related disorders have on annual budget. The true impact on economy is not usually...
      Speaker: Lana Morrow, PhD
      Presented at: Neuroscience Virtual Event Series 2014
      0
      MAR 19, 2014 | 7:00 AM
      Therapeutic Strategies for Cognitive Dysfunction in Down Syndrome
      Therapeutic Strategies for Cognitive Dysfunction in Down Syndrome
      Down syndrome (DS) is a complex multi-system disorder affecting more than 5.8 million individuals around the world and it causes significant physical, psychological, and cognitive abnormaliti...
      Speaker: Ahmad Salehi, MD, PhD
      Presented at: Neuroscience Virtual Event Series 2014
      15
      FEB 19, 2014 | 10:00 AM
      Next-generation sequencing applications in advanced cancer samples: Experience with Ion AmpliSeq custom panels
      Next-generation sequencing applications in advanced cancer samples:...
      Making precision cancer care a future reality requires novel approachesto finding treatment targets in cancers. Single-gene assays currently performed in clinical research laboratories are in...
      Speaker: Christopher Corless, MD, PhD
      Presented at: Advanced Genomics in Clinical and Translational Research - Winter
      122
    AUG 21, 2014 | 12:45 PM
    Predictive and not: understanding the mixed messages of our DNA
    Predictive and not: understanding the mixed messages of our DNA
    When whole genome and whole exome sequencing are introduced into health care, and offered directly to consumers in commercial settings, the landscape of genetic testing will drastically chang...
    Speaker: Cecile Janssens, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2014
    36
    AUG 21, 2014 | 11:30 AM
    Understanding the Genetics of Common Disease:  Using Big Data approaches to see the emergent whole
    Understanding the Genetics of Common Disease: Using Big Data...
    The comprehensive, multidimensional molecular characterization of tumors and the individuals in which they have developed is transforming cancer definition, diagnosis, treatment, and preventi...
    Speaker: Kenneth Buetow, PhD, FACMI
    Presented at: Genetics and Genomics Virtual Event Series 2014
    198
    AUG 21, 2014 | 9:45 AM
    Pathway based analyses for genetic susceptibility to cancer and autoimmune disease
    Pathway based analyses for genetic susceptibility to cancer and...
    In this presentation I describe pathway based analyses of genotyping data to identify pathways related to the development of complex diseases, with a focus on lung cancer and selected autoimm...
    Speaker: Christopher I Amos, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2014
    62
    AUG 21, 2014 | 8:45 AM
    From Genetics to Genetic Medicine: Gene Therapy for vision restoration as a case study
    From Genetics to Genetic Medicine: Gene Therapy for vision restoration...
    Gene therapy for two forms of inherited retinal degeneration have met promising safety and efficacy endpoints in early stage clinical trials. These approaches made use of a replication defect...
    Speaker: Luk H Vandenberghe, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2014
    0
    AUG 20, 2014 | 11:45 AM
    Ethical, Legal and Social Issues of Direct-to-Consumer Genetic Testing
    Ethical, Legal and Social Issues of Direct-to-Consumer Genetic...
    Direct-to-consumer (DTC) genetic testing can be understood as including two related aspects: first, the advertising of genetic tests directly to consumers; and second, the direct access or or...
    Speaker: Heidi C Howard, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2014
    25
     
     
  • AUG 20, 2014 | 10:45 AM
    OncoScan Assay for copy number from FFPE. Publications & cases on actionable CNV detection
    OncoScan Assay for copy number from FFPE. Publications & cases...
    A recent publication in Nature Genetics1 analyzed TCGA data, and classified solid tumors into two mutually exclusive classes: C class tumors, driven by copy number alterations; and M class tu...
    Speaker: Padma Sundar, MBA, MPH
    Presented at: Genetics and Genomics Virtual Event Series 2014
    14
    AUG 20, 2014 | 8:30 AM
    Actionable mutation detection with multiplex pcr-based targeted enrichment approach for next generation sequencing (NGS)
    Actionable mutation detection with multiplex pcr-based targeted...
    Next-generation sequencing (NGS) has revolutionized extraction of genomic information, facilitating rapid advances in the fields of clinical research and molecular diagnostics. However, c...
    Speaker: Vikram Devgan, PhD, MBA
    Presented at: Genetics and Genomics Virtual Event Series 2014
    16
    MAY 30, 2014 | 9:00 AM
    Panel Discussion: Vaginitis/vaginosis: Diagnosis and workup using conventional and molecular tests. Dr's Bowman and Wang
    Panel Discussion: Vaginitis/vaginosis: Diagnosis and workup using...
    Vaginitis and vaginosis, including Bacterial Vaginosis (BV), Vulvovaginal Candidiasis (VVC), and Trichomoniasis (TV), are extremely common conditions, consuming many healthcare resources and...
    Speaker: Cynthia Foss Bowman, MD and Guiqing Wang, MD, PhD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2014
    79
    MAY 30, 2014 | 7:30 AM
    Multiplexed Fusion Gene Detection using Next Generation Sequencing
    Multiplexed Fusion Gene Detection using Next Generation Sequencing
    As next-generation sequencing (NGS) platforms advance in their speed, ease-of-use, and cost-effectiveness, many translational researchers are transitioning from microarrays to RNA sequencing...
    Speaker: Kelli Bramlett and Jeoffrey Schageman
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2014
    82
    MAY 29, 2014 | 12:00 PM
    Pharmacogenomics and Pharmacometabolomics for Personalized Medicine
    Pharmacogenomics and Pharmacometabolomics for Personalized Medicine
    Pharmcogenomics (PGx) is the 2nd potential clinical application of genomic medicine, preceded by genomic application for cancer. In the recently published, 2012 Institute of Medicine report o...
    Speaker: Steven Wong, PhD, DABCC(TC), FACB
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2014
    36
     
     
  • MAY 29, 2014 | 10:30 AM
    Adding Value in Healthcare Delivery: Uses for Clinical Laboratory Informatics in Decision Support
    Adding Value in Healthcare Delivery: Uses for Clinical Laboratory...
    Clinical laboratory information provides decision support for most healthcare providers and impacts care processes and patient outcomes throughout the entire health services delivery system....
    Speaker: Elizabeth Kenimer Leibach, EdD, MS, MLS(ASCP), SBB
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2014
    70
    MAY 29, 2014 | 7:30 AM
    Identification of predictive biomarkers from high throughput drug combination screening data
    Identification of predictive biomarkers from high throughput drug...
    One of the major challenges to oncology based drug discovery and development has been the limited or incremental impact that many targeted agents have exhibited in the clinic. Understanding a...
    Speaker: Emma Bowden, PhD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2014
    20
    MAY 28, 2014 | 9:00 AM
    Keynote: Establishing an economic BRCA1 and BRCA2 (BRCA) gene analyses research workflow using custom AmpliSeq panel design and the Ion PGM System
    Keynote: Establishing an economic BRCA1 and BRCA2 (BRCA) gene...
    While the "Jolie effect" has refocused attention on the central role of BRCA gene analyses in the diagnosis and prevention of hereditary breast and ovarian cancer, there is a global disparity...
    Speaker: Jeffrey N Weitzel, MD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2014
    9
    MAR 20, 2014 | 2:00 PM
    Cross-talk & Developmental Programs A Key to Translational Stem Cell Biology
    Cross-talk & Developmental Programs A Key to Translational...
    The therapeutic utility of stem cells is rooted in an understanding -- and exploitation -- of their natural role from earliest development to lifes end. Their job is first to participate in o...
    Speaker: Evan W. Snyder, M.D., Ph.D., F.A.A.P
    Presented at: Neuroscience Virtual Event Series 2014
    94
    MAR 20, 2014 | 1:00 PM
    The role of high throughput sequencing in the research and diagnosis of neurodegenerative disorders
    The role of high throughput sequencing in the research and diagnosis...
    Using high throughput next-generation sequencing to simultaneously search large number of genes for pathogenic mutations has numerous advantages. It decreases the pressure to narrow the dif...
    Speaker: Peter L Nagy, MD, PhD
    Presented at: Neuroscience Virtual Event Series 2014
    0
     
     
  • MAR 20, 2014 | 12:00 PM
    Axonal Protein Synthesis in Neurodevelopment and -degeneration
    Axonal Protein Synthesis in Neurodevelopment and -degeneration
    Spatially restricted protein synthesis is an important mechanism for the development and maintenance of many morphologically polarized cells including neurons. While most proteins are synthes...
    Speaker: Ulrich Hengst, PhD
    Presented at: Neuroscience Virtual Event Series 2014
    84
    MAR 20, 2014 | 10:00 AM
    Neuroeconomy; Economic Impact of Neurodegenerative Diseases both in the US and Globally
    Neuroeconomy; Economic Impact of Neurodegenerative Diseases both...
    When speaking of neurodegenerative diseases, average public is not made aware of the true cost that brain related disorders have on annual budget. The true impact on economy is not usually...
    Speaker: Lana Morrow, PhD
    Presented at: Neuroscience Virtual Event Series 2014
    48
    MAR 20, 2014 | 8:00 AM
    Cross-talk & Developmental Programs A Key to Translational Stem Cell Biology
    Cross-talk & Developmental Programs A Key to Translational Stem...
    The therapeutic utility of stem cells is rooted in an understanding -- and exploitation -- of their natural role from earliest development to lifes end. Their job is first to participate in o...
    Speaker: Evan W. Snyder, M.D., Ph.D., F.A.A.P
    Presented at: Beckman Coulter Life Sciences Virtual Trade Show
    Sponsored By: Beckman Coulter Life Sciences, Beckman Coulter Life Sciences
    1
    MAR 20, 2014 | 7:00 AM
    Huntingtons Disease: Twenty years and counting
    Huntingtons Disease: Twenty years and counting
    Huntington's disease (HD) is a progressive, inherited, degenerative brain disorder that produces physical, mental and emotional changes. Named for George Huntington, the physician who fi...
    Speaker: Margaret Sutherland, PhD
    Presented at: Neuroscience Virtual Event Series 2014
    106
    MAR 19, 2014 | 11:00 AM
    When good neurons go bad: Dopamine neuron regulation and its disruption in schizophrenia and depression
    When good neurons go bad: Dopamine neuron regulation and its disruption...
    ...
    Speaker: Anthony Grace, PhD
    Presented at: Neuroscience Virtual Event Series 2014
    36
     
     
  • MAR 19, 2014 | 10:00 AM
    MS Bioscreen: From the Bedside to the Bench and Back
    MS Bioscreen: From the Bedside to the Bench and Back
    We present a personalized medicine suite of software applications developed at UCSF for multiple sclerosis (MS): the MS Bioscreen. This new tool addresses the challenges of the dynamic manage...
    Speaker: Pierre-Antoine Gourraud, PhD, MPH
    Presented at: Neuroscience Virtual Event Series 2014
    25
    MAR 19, 2014 | 9:00 AM
    Brain Computer Interfaces: Neurotech in the Future of Neuroscience
    Brain Computer Interfaces: Neurotech in the Future of Neuroscience
    When speaking of neurodegenerative diseases, average public is not made aware of the true cost that brain related disorders have on annual budget. The true impact on economy is not usually...
    Speaker: Lana Morrow, PhD
    Presented at: Neuroscience Virtual Event Series 2014
    0
    MAR 19, 2014 | 7:00 AM
    Therapeutic Strategies for Cognitive Dysfunction in Down Syndrome
    Therapeutic Strategies for Cognitive Dysfunction in Down Syndrome
    Down syndrome (DS) is a complex multi-system disorder affecting more than 5.8 million individuals around the world and it causes significant physical, psychological, and cognitive abnormaliti...
    Speaker: Ahmad Salehi, MD, PhD
    Presented at: Neuroscience Virtual Event Series 2014
    15
    FEB 19, 2014 | 10:00 AM
    Next-generation sequencing applications in advanced cancer samples: Experience with Ion AmpliSeq custom panels
    Next-generation sequencing applications in advanced cancer samples:...
    Making precision cancer care a future reality requires novel approachesto finding treatment targets in cancers. Single-gene assays currently performed in clinical research laboratories are in...
    Speaker: Christopher Corless, MD, PhD
    Presented at: Advanced Genomics in Clinical and Translational Research - Winter
    122
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