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    Tumor associated macrophages

    Tumor associated macrophages (TAMs) are a subset of myeloid-derived immune cells that cause immunosuppression in a tumor microenvironment. TAMS produce cytokines, chemical messengers that regulate immune responses, that inhibit the anti-tumor immune response thus promoting tumor growth and development.

    Webinars

    • FEB 15, 2024 | 8:00 AM
      Breathe Easy with Better Models: Research for Activating Macrophages and Dendritic Cells with Nanomedicine in Lung Carcinoma
      Breathe Easy with Better Models: Research for Activating Macrophages...
      Macrophages can mediate phagocytosis of cancer cells and cytotoxic tumor killing, and engage in effective bidirectional interactions with components of the innate and adaptive immune system....
      Speaker: Guo Yuedong, Ph.D.
      Sponsored By: Curiox
      10 1
      MAY 19, 2022 | 8:00 AM
      Automated sample preparation for reproducible clinical proteomics
      Automated sample preparation for reproducible clinical proteomics
      Date: May 19, 2022 Time: 8:00am (PDT), 11:00pm (EDT), 5:00pm (CEST) Mass spectrometry (MS)-based proteomic technologies are increasingly applied in a clinical context for disease classific...
      Speaker: Jeroen Krijgsveld , Nicolas Autret, PhD , Ignasi Forné, PhD
      Sponsored By: Covaris, Inc.
      14
      JUN 02, 2021 | 12:00 AM
      EZH2 as an Actionable Therapeutic Target to Enhance Anti-Tumor Immune Response In Prostate Cancer
      EZH2 as an Actionable Therapeutic Target to Enhance Anti-Tumor...
      Prostate cancers are considered immunologically ‘cold’ tumors given the very few patients who respond to checkpoint inhibitor therapy (CPI). Recently, enrichment of interferon st...
      Speaker: Leigh Ellis, Ph.D.
      Presented at: Immuno-Oncology Virtual Event Series 2021
      1
      FEB 09, 2021 | 9:00 AM
      Development and analytical validation of prognostic biomarkers for metastasis
      Development and analytical validation of prognostic biomarkers...
      Date: February 9, 2020 Time: 9:00am (PST), 12:00pm (EST) 90% of breast cancer mortality is caused by distant metastasis, a process that involves both dissemination of cancer cells to distant...
      Speaker: David Entenberg, PhD
      Sponsored By: Visiopharm®
      20
      OCT 20, 2020 | 9:00 AM
      Understanding how in vitro macrophage assays drive IO drug development forward
      Understanding how in vitro macrophage assays drive IO drug development...
      DATE: October 20th, 2020 TIME: 08:00am PT, 11:00am ET Tumor-associated macrophages (TAMs) are key cells in the tumor microenvironment (TME) with diverse immune functions that have a major in...
      Speaker: Thibaut Janss, PhD
      Sponsored By: Miltenyi Biotec
      6 1
      SEP 23, 2020 | 12:00 PM
      Mass Cytometry in Translational Research: Session II
      Mass Cytometry in Translational Research: Session II
      B cells and tertiary lymphoid structures (TLS) promote immunotherapy response 1:00–1:30 pm PDT Presented By: Rafet Basar, MD...
      Speaker: Handan Xiang, PhD , Pei-Yu Chen, PhD , Hiranmayi Ravichandran, MS , Rafet Basar, MD , Amir Horowitz, PhD
      Presented at: 9th Annual Fluidigm Mass Cytometry Virtual Summit
      2
      SEP 17, 2020 | 11:00 AM
      Host and Viral Transcriptomes During COVID-19 Infection
      Host and Viral Transcriptomes During COVID-19 Infection
      In less than nine months, the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has killed hundreds of thousands of people, including >23,000 in New York City (NYC) alone. The...
      Speaker: Christopher E. Mason, PhD
      Presented at: Coronavirus Series
      3
      SEP 01, 2020 | 8:00 AM
      Single-cell analyses of checkpoint-inhibition-induced myocarditis: implications into mechanisms of severe immune-related adverse events
      Single-cell analyses of checkpoint-inhibition-induced myocarditis:...
      DATE: September 1, 2020 TIME: 8:00am PT, 11:00am ET Nearly half of all cancer patients are eligible to receive treatment with immune checkpoint inhibitors (ICI). Thus, preventing, identifyin...
      Speaker: Justin Balko
      Sponsored By: Thermo Fisher Scientific
      20 1
      JUL 07, 2020 | 11:00 AM
      Comprehensive landscape of the tumor microenvironment analyzed with CyTOF® technology
      Comprehensive landscape of the tumor microenvironment analyzed...
      Immune escape mechanisms such as the induction/recruitment of immunosuppressive cells and the increased expression of various immunosuppressive molecules including PD-1/PD-1 ligands are esse...
      Speaker: Hiroyoshi Nishikawa, MD, PhD
      Presented at: Fluidigm Infectious Disease and Oncology Virtual Summit
      2
      JUL 07, 2020 | 6:00 AM
      Single-cell mapping of human brain cancer reveals tumor-driven education of tumor-associated leukocytes
      Single-cell mapping of human brain cancer reveals tumor-driven...
      Brain malignancies can either originate from within the CNS (gliomas) or invade from other locations in the body (metastases). A highly immunosuppressive tumor microenvironment (TME) influen...
      Speaker: Burkhard Becher, PhD
      Presented at: Fluidigm Infectious Disease and Oncology Virtual Summit
      1
      MAY 20, 2020 | 12:45 PM
      Molecular and Immunologic Profiling of CD8+ T Cell Responses in Patients Receiving a Multiple Antigen-Engineered Dendritic Cell Vaccine
      Molecular and Immunologic Profiling of CD8+ T Cell Responses in...
      Background: Despite the immunogenicity and safety profile of dendritic cell (DC) vaccines, the importance of vaccine-induced antigen-specific T cell responses is unclear across clinical tria...
      Speaker: Juraj Adamik, PhD
      Presented at: Advancing Science - A Virtual Oncology Conference
      1
      MAY 19, 2020 | 11:45 AM
      Discovery of Biomarkers Associated with Benefit From PD-1 Checkpoint Blockade in Non-small-cell Lung Cancer (NSCLC) Using High-plex Digital Spatial Profiling
      Discovery of Biomarkers Associated with Benefit From PD-1 Checkpoint...
      The majority of patients with advanced NSCLC do not respond to monotherapy with PD-1 axis inhibition, and more robust predictive biomarkers are needed. In this study, we assessed tumor sampl...
      Speaker: Jon Zugazagoitia, MD, PhD
      Presented at: Advancing Science - A Virtual Oncology Conference
      1 1
      MAY 19, 2020 | 11:15 AM
      Digital Spatial Mapping of the Immune Landscape of Triple Negative Breast Cancer Reveals Novel Features of Immune-tumor Cell Interaction
      Digital Spatial Mapping of the Immune Landscape of Triple Negative...
      Background: Growing evidence supports the critical role of preexisting immune response in triple negative breast cancer (TNBC). However, there are limitations with current evaluation approac...
      Speaker: E. Aubrey Thompson, PhD
      Presented at: Advancing Science - A Virtual Oncology Conference
      1
      APR 14, 2020 | 9:00 AM
      Gibco Cell Culture Heroes: Work From Home Edition
      Gibco Cell Culture Heroes: Work From Home Edition
      DATE: April 14, 2020 TIME: 9:00am PDT, 12:00pm EDT Besides being Gibco Cell Culture Heroes, what do Vivek, Sandra, Daisy, Ameet and Kristine all have in common? They are all stuck at home fo...
      Speaker: Kristine Wadosky, PhD , Ameet Chimote, PhD , Elizabeth Delery, PhD , Daisy Shu, B.Optom, PhD , Vivek Kamat, PhD , Sandra Hammer, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      12 1
      AUG 15, 2019 | 9:00 AM
      Understanding and ameliorating radiation-induced damage to oligodendrocytes
      Understanding and ameliorating radiation-induced damage to oligodendrocytes
      DATE: August 15, 2019TIME: 9:00am PDT, 12:00pm EDT Radiation therapy is a critical tool for the treatment of brain tumors, however, exposure to high doses of ionizing radiation...
      Speaker: Alexandra Taraboletti, PHD
      Sponsored By: Thermo Fisher Scientific/Gibco
      6
      JUL 31, 2019 | 9:00 AM
      Choroid Plexus Epithelial Cell 2D & Modified 3D Cell Culture Model
      Choroid Plexus Epithelial Cell 2D & Modified 3D Cell Culture Model
      DATE: July 31, 2019TIME: 9:00am PT, 12:00pm ET The choroid plexus, which makes up the blood-cerebrospinal fluid barrier in the central nervous system (CNS), lines the ventricle...
      Speaker: Elizabeth Delery, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      7 1
      DEC 05, 2018 | 8:00 PM
      The Use of Flow Cytometry to Identify Cancer Stem Cells in Primary Tumors and in Circulation
      The Use of Flow Cytometry to Identify Cancer Stem Cells in Primary...
      DATE: December 05, 2018TIME:  08:00 PSTWhat is desperately needed are methods to detect cells that cause metastasis–known as cancer stem cells (CSC), a subpopulation of...
      Speaker: Bruno Sainz, PhD
      Sponsored By: Thermo Fisher Scientific
      5 3
      DEC 05, 2018 | 7:00 AM
      The Use of Flow Cytometry to Identify Cancer Stem Cells in Primary Tumors and in Circulation
      The Use of Flow Cytometry to Identify Cancer Stem Cells in Primary...
      DATE: December 05, 2018TIME:  07:00 PSTWhat is desperately needed are methods to detect cells that cause metastasis–known as cancer stem cells (CSC), a subpopulation of...
      Speaker: Bruno Sainz, PhD
      Sponsored By: Thermo Fisher Scientific
      7
      OCT 10, 2018 | 10:30 AM
      Metabolic Networks in the Tumor Microenvironment
      Metabolic Networks in the Tumor Microenvironment
      Pancreatic tumors are dynamic pseudo-organs that contain numerous cell types interacting to create unique physiology. A typical pancreatic tumor is made up largely of stromal fibroblasts and...
      Speaker: Costas A. Lyssiotis, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
      Sponsored By: Agilent
      2
      SEP 30, 2015 | 7:30 AM
      Humanized NSGTM Mice for Evaluation of Immuno-Oncology Therapeutics
      Humanized NSGTM Mice for Evaluation of Immuno-Oncology Therapeutics
      Using the NSGTM mouse (NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ), JAX In Vivo Pharmacology Services has combined the human CD34+ hematopoietic stem cell engrafted NSGTM (hu-CD34 NSGTM) with human pat...
      Speaker: Brian Soper, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2015
      2
      OCT 29, 2014 | 12:00 PM
      Obesity, weight loss, and the microenvironment in basal-like breast cancer
      Obesity, weight loss, and the microenvironment in basal-like breast...
      Obesity is associated with an aggressive subtype of breast cancer called basal-like breast cancer (BBC). Using C3(1)-TAg mice, a genetically engineered mouse model that resembles human BBC, w...
      Speaker: Liza Makowski, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      12
    FEB 15, 2024 | 8:00 AM
    Breathe Easy with Better Models: Research for Activating Macrophages and Dendritic Cells with Nanomedicine in Lung Carcinoma
    Breathe Easy with Better Models: Research for Activating Macrophages...
    Macrophages can mediate phagocytosis of cancer cells and cytotoxic tumor killing, and engage in effective bidirectional interactions with components of the innate and adaptive immune system....
    Speaker: Guo Yuedong, Ph.D.
    Sponsored By: Curiox
    10 1
    MAY 19, 2022 | 8:00 AM
    Automated sample preparation for reproducible clinical proteomics
    Automated sample preparation for reproducible clinical proteomics
    Date: May 19, 2022 Time: 8:00am (PDT), 11:00pm (EDT), 5:00pm (CEST) Mass spectrometry (MS)-based proteomic technologies are increasingly applied in a clinical context for disease classific...
    Speaker: Jeroen Krijgsveld , Nicolas Autret, PhD , Ignasi Forné, PhD
    Sponsored By: Covaris, Inc.
    14
    JUN 02, 2021 | 12:00 AM
    EZH2 as an Actionable Therapeutic Target to Enhance Anti-Tumor Immune Response In Prostate Cancer
    EZH2 as an Actionable Therapeutic Target to Enhance Anti-Tumor...
    Prostate cancers are considered immunologically ‘cold’ tumors given the very few patients who respond to checkpoint inhibitor therapy (CPI). Recently, enrichment of interferon st...
    Speaker: Leigh Ellis, Ph.D.
    Presented at: Immuno-Oncology Virtual Event Series 2021
    1
    FEB 09, 2021 | 9:00 AM
    Development and analytical validation of prognostic biomarkers for metastasis
    Development and analytical validation of prognostic biomarkers...
    Date: February 9, 2020 Time: 9:00am (PST), 12:00pm (EST) 90% of breast cancer mortality is caused by distant metastasis, a process that involves both dissemination of cancer cells to distant...
    Speaker: David Entenberg, PhD
    Sponsored By: Visiopharm®
    20
    OCT 20, 2020 | 9:00 AM
    Understanding how in vitro macrophage assays drive IO drug development forward
    Understanding how in vitro macrophage assays drive IO drug development...
    DATE: October 20th, 2020 TIME: 08:00am PT, 11:00am ET Tumor-associated macrophages (TAMs) are key cells in the tumor microenvironment (TME) with diverse immune functions that have a major in...
    Speaker: Thibaut Janss, PhD
    Sponsored By: Miltenyi Biotec
    6 1
     
     
  • SEP 23, 2020 | 12:00 PM
    Mass Cytometry in Translational Research: Session II
    Mass Cytometry in Translational Research: Session II
    B cells and tertiary lymphoid structures (TLS) promote immunotherapy response 1:00–1:30 pm PDT Presented By: Rafet Basar, MD...
    Speaker: Handan Xiang, PhD , Pei-Yu Chen, PhD , Hiranmayi Ravichandran, MS , Rafet Basar, MD , Amir Horowitz, PhD
    Presented at: 9th Annual Fluidigm Mass Cytometry Virtual Summit
    2
    SEP 17, 2020 | 11:00 AM
    Host and Viral Transcriptomes During COVID-19 Infection
    Host and Viral Transcriptomes During COVID-19 Infection
    In less than nine months, the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has killed hundreds of thousands of people, including >23,000 in New York City (NYC) alone. The...
    Speaker: Christopher E. Mason, PhD
    Presented at: Coronavirus Series
    3
    SEP 01, 2020 | 8:00 AM
    Single-cell analyses of checkpoint-inhibition-induced myocarditis: implications into mechanisms of severe immune-related adverse events
    Single-cell analyses of checkpoint-inhibition-induced myocarditis:...
    DATE: September 1, 2020 TIME: 8:00am PT, 11:00am ET Nearly half of all cancer patients are eligible to receive treatment with immune checkpoint inhibitors (ICI). Thus, preventing, identifyin...
    Speaker: Justin Balko
    Sponsored By: Thermo Fisher Scientific
    20 1
    JUL 07, 2020 | 11:00 AM
    Comprehensive landscape of the tumor microenvironment analyzed with CyTOF® technology
    Comprehensive landscape of the tumor microenvironment analyzed...
    Immune escape mechanisms such as the induction/recruitment of immunosuppressive cells and the increased expression of various immunosuppressive molecules including PD-1/PD-1 ligands are esse...
    Speaker: Hiroyoshi Nishikawa, MD, PhD
    Presented at: Fluidigm Infectious Disease and Oncology Virtual Summit
    2
    JUL 07, 2020 | 6:00 AM
    Single-cell mapping of human brain cancer reveals tumor-driven education of tumor-associated leukocytes
    Single-cell mapping of human brain cancer reveals tumor-driven...
    Brain malignancies can either originate from within the CNS (gliomas) or invade from other locations in the body (metastases). A highly immunosuppressive tumor microenvironment (TME) influen...
    Speaker: Burkhard Becher, PhD
    Presented at: Fluidigm Infectious Disease and Oncology Virtual Summit
    1
     
     
  • MAY 20, 2020 | 12:45 PM
    Molecular and Immunologic Profiling of CD8+ T Cell Responses in Patients Receiving a Multiple Antigen-Engineered Dendritic Cell Vaccine
    Molecular and Immunologic Profiling of CD8+ T Cell Responses in...
    Background: Despite the immunogenicity and safety profile of dendritic cell (DC) vaccines, the importance of vaccine-induced antigen-specific T cell responses is unclear across clinical tria...
    Speaker: Juraj Adamik, PhD
    Presented at: Advancing Science - A Virtual Oncology Conference
    1
    MAY 19, 2020 | 11:45 AM
    Discovery of Biomarkers Associated with Benefit From PD-1 Checkpoint Blockade in Non-small-cell Lung Cancer (NSCLC) Using High-plex Digital Spatial Profiling
    Discovery of Biomarkers Associated with Benefit From PD-1 Checkpoint...
    The majority of patients with advanced NSCLC do not respond to monotherapy with PD-1 axis inhibition, and more robust predictive biomarkers are needed. In this study, we assessed tumor sampl...
    Speaker: Jon Zugazagoitia, MD, PhD
    Presented at: Advancing Science - A Virtual Oncology Conference
    1 1
    MAY 19, 2020 | 11:15 AM
    Digital Spatial Mapping of the Immune Landscape of Triple Negative Breast Cancer Reveals Novel Features of Immune-tumor Cell Interaction
    Digital Spatial Mapping of the Immune Landscape of Triple Negative...
    Background: Growing evidence supports the critical role of preexisting immune response in triple negative breast cancer (TNBC). However, there are limitations with current evaluation approac...
    Speaker: E. Aubrey Thompson, PhD
    Presented at: Advancing Science - A Virtual Oncology Conference
    1
    APR 14, 2020 | 9:00 AM
    Gibco Cell Culture Heroes: Work From Home Edition
    Gibco Cell Culture Heroes: Work From Home Edition
    DATE: April 14, 2020 TIME: 9:00am PDT, 12:00pm EDT Besides being Gibco Cell Culture Heroes, what do Vivek, Sandra, Daisy, Ameet and Kristine all have in common? They are all stuck at home fo...
    Speaker: Kristine Wadosky, PhD , Ameet Chimote, PhD , Elizabeth Delery, PhD , Daisy Shu, B.Optom, PhD , Vivek Kamat, PhD , Sandra Hammer, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    12 1
    AUG 15, 2019 | 9:00 AM
    Understanding and ameliorating radiation-induced damage to oligodendrocytes
    Understanding and ameliorating radiation-induced damage to oligodendrocytes
    DATE: August 15, 2019TIME: 9:00am PDT, 12:00pm EDT Radiation therapy is a critical tool for the treatment of brain tumors, however, exposure to high doses of ionizing radiation...
    Speaker: Alexandra Taraboletti, PHD
    Sponsored By: Thermo Fisher Scientific/Gibco
    6
     
     
  • JUL 31, 2019 | 9:00 AM
    Choroid Plexus Epithelial Cell 2D & Modified 3D Cell Culture Model
    Choroid Plexus Epithelial Cell 2D & Modified 3D Cell Culture Model
    DATE: July 31, 2019TIME: 9:00am PT, 12:00pm ET The choroid plexus, which makes up the blood-cerebrospinal fluid barrier in the central nervous system (CNS), lines the ventricle...
    Speaker: Elizabeth Delery, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    7 1
    DEC 05, 2018 | 8:00 PM
    The Use of Flow Cytometry to Identify Cancer Stem Cells in Primary Tumors and in Circulation
    The Use of Flow Cytometry to Identify Cancer Stem Cells in Primary...
    DATE: December 05, 2018TIME:  08:00 PSTWhat is desperately needed are methods to detect cells that cause metastasis–known as cancer stem cells (CSC), a subpopulation of...
    Speaker: Bruno Sainz, PhD
    Sponsored By: Thermo Fisher Scientific
    5 3
    DEC 05, 2018 | 7:00 AM
    The Use of Flow Cytometry to Identify Cancer Stem Cells in Primary Tumors and in Circulation
    The Use of Flow Cytometry to Identify Cancer Stem Cells in Primary...
    DATE: December 05, 2018TIME:  07:00 PSTWhat is desperately needed are methods to detect cells that cause metastasis–known as cancer stem cells (CSC), a subpopulation of...
    Speaker: Bruno Sainz, PhD
    Sponsored By: Thermo Fisher Scientific
    7
    OCT 10, 2018 | 10:30 AM
    Metabolic Networks in the Tumor Microenvironment
    Metabolic Networks in the Tumor Microenvironment
    Pancreatic tumors are dynamic pseudo-organs that contain numerous cell types interacting to create unique physiology. A typical pancreatic tumor is made up largely of stromal fibroblasts and...
    Speaker: Costas A. Lyssiotis, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2018
    Sponsored By: Agilent
    2
    SEP 30, 2015 | 7:30 AM
    Humanized NSGTM Mice for Evaluation of Immuno-Oncology Therapeutics
    Humanized NSGTM Mice for Evaluation of Immuno-Oncology Therapeutics
    Using the NSGTM mouse (NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ), JAX In Vivo Pharmacology Services has combined the human CD34+ hematopoietic stem cell engrafted NSGTM (hu-CD34 NSGTM) with human pat...
    Speaker: Brian Soper, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2015
    2
     
     
  • OCT 29, 2014 | 12:00 PM
    Obesity, weight loss, and the microenvironment in basal-like breast cancer
    Obesity, weight loss, and the microenvironment in basal-like breast...
    Obesity is associated with an aggressive subtype of breast cancer called basal-like breast cancer (BBC). Using C3(1)-TAg mice, a genetically engineered mouse model that resembles human BBC, w...
    Speaker: Liza Makowski, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    12
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