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    Tumor & Immunity

    Tumors and the immune response interact in various ways. Tumors try to suppress the immune response in an effort to promote their growth and survival. The anti-tumor immune response, on the other hand, identifies tumor cells and kills them. Both tumors and the immune response elicit various mechanisms to combat the actions of the other.

    Webinars

    • SEP 17, 2020 | 12:45 PM
      Stimuli-responsive Nanomaterials for Imaging Immunotherapy Response
      Stimuli-responsive Nanomaterials for Imaging Immunotherapy Response
      Immunotherapy such as immune checkpoint inhibitor antibodies have revolutionized the treatments for hard-to-treat cancers, with durable responses observed in clinics. However, the overall re...
      Speaker: Ashish Kulkarni, PhD
      Presented at: 7th Annual Conference: SBI2 High Content
      2
      SEP 17, 2020 | 12:15 PM
      Metabolic imaging of cellular heterogeneity in patient-derived cancer organoids
      Metabolic imaging of cellular heterogeneity in patient-derived...
      Abnormal cellular metabolism is a hallmark of many diseases, yet there is an absence of quantitative methods to dynamically image metabolism with cellular-level resolution. Optical metabolic...
      Speaker: Melissa C. Skala, PhD
      Presented at: 7th Annual Conference: SBI2 High Content
      1
      SEP 16, 2020 | 1:30 PM
      Multiplexed Imaging to Understand the High-Dimensional Pathology of Human Cancer
      Multiplexed Imaging to Understand the High-Dimensional Pathology...
      The recent development of highly multiplexed methods for imaging tissues from patients and mouse models promises to fundamentally advance research in tissue biology and disease. These new te...
      Speaker: Sandro Santagata, MD, PhD
      Presented at: 7th Annual Conference: SBI2 High Content
      1
      SEP 16, 2020 | 9:00 AM
      Deep multi-omic phenotyping of biospecimens for immuno-oncology applications
      Deep multi-omic phenotyping of biospecimens for immuno-oncology...
      Date: September 16, 2020 Time: 9:00am PTD, 12:00pm EDT Harnessing the power of the host immune system to treat diseases has been transformational in patient care. Physiologically relevant ce...
      Speaker: Dr. Shawn Fahl
      Sponsored By: Miltenyi Biotec
      11
      SEP 15, 2020 | 8:00 AM
      Next generation ultra high content analysis of the tumor immune microenvironment using MICS technology
      Next generation ultra high content analysis of the tumor immune...
      DATE: September 15, 2020 TIME: 08:00am PT Tumorigenesis and cancer progression are affected by the tumor immune microenvironment (TIME). The TIME not only influences the efficiency of existi...
      Speaker: Stefan Eulitz
      Sponsored By: Miltenyi Biotec
      15 2
      SEP 08, 2020 | 11:00 PM
      Recombination, lineage-specific mutations and the emergence of SARS-CoV-2
      Recombination, lineage-specific mutations and the emergence of...
      The recent outbreak of SARS-CoV-2 underscores the need for understanding the evolutionary processes that drive the emergence and adaptation of zoonotic viruses in humans. Here, we show that...
      Speaker: Ioan Filip, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      1
      SEP 01, 2020 | 8:00 AM
      Single-cell analyses of checkpoint-inhibition-induced myocarditis: implications into mechanisms of severe immune-related adverse events
      Single-cell analyses of checkpoint-inhibition-induced myocarditis:...
      DATE: September 1, 2020 TIME: 8:00am PT, 11:00am ET Nearly half of all cancer patients are eligible to receive treatment with immune checkpoint inhibitors (ICI). Thus, preventing, identifyin...
      Speaker: Justin Balko
      Sponsored By: Thermo Fisher Scientific
      20 1
      AUG 26, 2020 | 8:00 AM
      Bio-Layer Interferometry as a strategic platform to validate covalent "proximity inducing" small molecules with synthetic tumor Immunotherapeutic applications
      Bio-Layer Interferometry as a strategic platform to validate covalent...
      DATE: August 26, 2020 TIME: 8:00 am PDT The host immune "recognition" of cancer forms the basis of modern tumor immmunotherapy, a highly targeted treatment option with the demonstr...
      Speaker: Anthony Rullo , Nilshad Salim, Ph.D.
      Sponsored By: Sartorius
      13
      JUL 29, 2020 | 5:00 PM
      Enabling 3D T-Cell, Tumoroid Invasion, and Organoid Assays Through the Incorporation of Live Cellular Imaging
      Enabling 3D T-Cell, Tumoroid Invasion, and Organoid Assays Through...
      Over the last decade the cancer research field has seen a number of advances aimed at increasing the efficacy of treatments, reducing toxic side effects, and decreasing attrition rates of dr...
      Speaker: Brad Larson
      Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
      2
      JUL 29, 2020 | 3:00 PM
      Advances and trends enabling the growth of immune-based cancer research and therapeutics
      Advances and trends enabling the growth of immune-based cancer...
      With the recent successes of immunotherapies, a fresh breeze of optimism in the fight against cancer has reinvigorated the industry. Perhaps the greatest legacy will be the realization of th...
      Speaker: David Ferrick, PhD
      Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
      3
      JUL 29, 2020 | 12:00 PM
      Linking Cancer Metabolism to Neurodegeneration
      Linking Cancer Metabolism to Neurodegeneration
      The major function of mitochondria in cellular homeostasis has been the generation of ATP through oxidative phosphorylation. However, we have previously demonstrated that mitochondria can se...
      Speaker: Navdeep S. Chandel PhD
      Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
      3
      JUL 29, 2020 | 10:00 AM
      Metabolic control of T cell tolerance and antitumor immunity
      Metabolic control of T cell tolerance and antitumor immunity
      Coordination of immune cell metabolic programs with cell fate and state is a fundamental determinant of immune responses. Emerging evidence highlights that the interplay between immune signa...
      Speaker: Hongbo Chi, PhD
      Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
      1
      JUL 29, 2020 | 7:00 AM
      What intratumoral Tregs eat makes them strong, but vulnerable: a new metabolic intervention for cancer immunotherapy
      What intratumoral Tregs eat makes them strong, but vulnerable:...
      Metabolic reprogramming is critical for governing proper T cell immune responses, including activation, production of effector molecule, migration and differentiation. The metabolic stress T...
      Speaker: Ping-Chih Ho, PhD
      Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
      2
      JUL 07, 2020 | 11:00 AM
      Comprehensive landscape of the tumor microenvironment analyzed with CyTOF® technology
      Comprehensive landscape of the tumor microenvironment analyzed...
      Immune escape mechanisms such as the induction/recruitment of immunosuppressive cells and the increased expression of various immunosuppressive molecules including PD-1/PD-1 ligands are esse...
      Speaker: Hiroyoshi Nishikawa, MD, PhD
      Presented at: Fluidigm Infectious Disease and Oncology Virtual Summit
      2
      JUL 07, 2020 | 9:30 AM
      Evaluating tumor-immune cell interactions in human lung cancer using multiparametric and spatially resolved tissue analysis
      Evaluating tumor-immune cell interactions in human lung cancer...
      ...
      Speaker: Kurt Schalper, MD, PhD
      Presented at: Fluidigm Infectious Disease and Oncology Virtual Summit
      1
      JUL 07, 2020 | 9:00 AM
      Enhancing risk stratification in early colon cancer with TNM-I (Immune) staging: focus on stage II T4N0 patients
      Enhancing risk stratification in early colon cancer with TNM-I...
      DATE: July 07, 2020 TIME: 9:00 am PDT The widely used TNM staging system is poorly predictive of response to adjuvant chemotherapy in Stage II and III colon cancer. As a result, there is ove...
      Speaker: Jérôme Galon, Ph.D , Graham Poage, Ph.D
      Sponsored By: HalioDx
      22 14
      JUL 07, 2020 | 7:30 AM
      Deciphering T cell heterogeneity in humans through analysis of antigen-specificity
      Deciphering T cell heterogeneity in humans through analysis of...
      In line with the role of T cells as critical mediators of the adaptive immune response, recombinational and junctional diversity of the T cell receptor makes each T cell almost entirely uniq...
      Speaker: Evan Newell, PhD
      Presented at: Fluidigm Infectious Disease and Oncology Virtual Summit
      2
      JUL 07, 2020 | 6:30 AM
      Deep immunophenotyping of cancer microenvironments by Imaging Mass Cytometry™
      Deep immunophenotyping of cancer microenvironments by Imaging...
      Multiplex immunophenotyping technologies are indispensable for a deeper understanding of biological systems. Until recently, high-dimensional cellular analyses implied the loss of tissue con...
      Speaker: Noel de Miranda, PhD
      Presented at: Fluidigm Infectious Disease and Oncology Virtual Summit
      1
      JUL 07, 2020 | 6:00 AM
      Single-cell mapping of human brain cancer reveals tumor-driven education of tumor-associated leukocytes
      Single-cell mapping of human brain cancer reveals tumor-driven...
      Brain malignancies can either originate from within the CNS (gliomas) or invade from other locations in the body (metastases). A highly immunosuppressive tumor microenvironment (TME) influen...
      Speaker: Burkhard Becher, PhD
      Presented at: Fluidigm Infectious Disease and Oncology Virtual Summit
      1
      JUL 02, 2020 | 12:15 PM
      Microsatellite instability analysis for studying immunotherapy and Lynch syndrome-related cancers
      Microsatellite instability analysis for studying immunotherapy...
      Microsatellite instability (MSI) is a hypermutation phenotype that results from impaired DNA mismatch repair (MMR). The presence of high levels of MSI (MSI-H) is potentially predictive of Ly...
      Speaker: Charles Baudo, PhD
      Presented at: APJ Virtual Genetic Solutions Tour 2020
      1
      JUN 30, 2020 | 10:00 AM
      COVID-19 Serology Assays and Cell Therapy Strategies
      COVID-19 Serology Assays and Cell Therapy Strategies
      DATE: June 30, 2020 TIME: 10:00 am PDT, 1:00 pm EDT COVID-19 is a highly pathogenic disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We have assembled a panel...
      Speaker: Fatima Amanat , Dean Lee , Lior Raviv
      Sponsored By: Thermo Fisher Scientific/Gibco
      30 1
      JUN 30, 2020 | 9:00 AM
      Quality Control for the Pharmaceutical Industry; Stage 3, Continued Verification, in the Lifecycle of Analytical Procedures
      Quality Control for the Pharmaceutical Industry; Stage 3, Continued...
      DATE: June 30, 2020 TIME: 9:00am PDT, 12:00pm EDT QC laboratories perform a critical role in demonstrating pharmaceutical products are consistently manufactured, safe, potent, and pure. At t...
      Speaker: Jane Weitzel
      Sponsored By: Sartorius
      17 1
      JUN 26, 2020 | 8:00 AM
      Next-Generation Cytogenetics: international, multi-center study of chromosomal aberrations in constitutional diseases and leukemia with Bionano genome imaging
      Next-Generation Cytogenetics: international, multi-center study...
      DATE: June 26, 2020 TIME: 8:00am PT Structural variants (SVs) are an important source of genetic variation in the human genome and they are involved in a multitude of human diseases as well...
      Speaker: Alexander Hoischen , Laila El Khattabi
      Sponsored By: Bionano
      16
      JUN 17, 2020 | 1:30 PM
      Insights into the Pathogenesis of COVID-19 as Revealed by Spatial Biology
      Insights into the Pathogenesis of COVID-19 as Revealed by Spatial...
      Understanding the complex interplay between a pathogen and the host response is important to developing effective vaccines and therapeutics. The nCounter® Analysis System and GeoMx®...
      Speaker: Joseph M. Beechem, PhD , Christopher E. Mason, PhD , Robert Schwartz, PhD
      Presented at: Coronavirus Series
      Sponsored By: NanoString Technologies
      9
    SEP 17, 2020 | 12:45 PM
    Stimuli-responsive Nanomaterials for Imaging Immunotherapy Response
    Stimuli-responsive Nanomaterials for Imaging Immunotherapy Response
    Immunotherapy such as immune checkpoint inhibitor antibodies have revolutionized the treatments for hard-to-treat cancers, with durable responses observed in clinics. However, the overall re...
    Speaker: Ashish Kulkarni, PhD
    Presented at: 7th Annual Conference: SBI2 High Content
    2
    SEP 17, 2020 | 12:15 PM
    Metabolic imaging of cellular heterogeneity in patient-derived cancer organoids
    Metabolic imaging of cellular heterogeneity in patient-derived...
    Abnormal cellular metabolism is a hallmark of many diseases, yet there is an absence of quantitative methods to dynamically image metabolism with cellular-level resolution. Optical metabolic...
    Speaker: Melissa C. Skala, PhD
    Presented at: 7th Annual Conference: SBI2 High Content
    1
    SEP 16, 2020 | 1:30 PM
    Multiplexed Imaging to Understand the High-Dimensional Pathology of Human Cancer
    Multiplexed Imaging to Understand the High-Dimensional Pathology...
    The recent development of highly multiplexed methods for imaging tissues from patients and mouse models promises to fundamentally advance research in tissue biology and disease. These new te...
    Speaker: Sandro Santagata, MD, PhD
    Presented at: 7th Annual Conference: SBI2 High Content
    1
    SEP 16, 2020 | 9:00 AM
    Deep multi-omic phenotyping of biospecimens for immuno-oncology applications
    Deep multi-omic phenotyping of biospecimens for immuno-oncology...
    Date: September 16, 2020 Time: 9:00am PTD, 12:00pm EDT Harnessing the power of the host immune system to treat diseases has been transformational in patient care. Physiologically relevant ce...
    Speaker: Dr. Shawn Fahl
    Sponsored By: Miltenyi Biotec
    11
    SEP 15, 2020 | 8:00 AM
    Next generation ultra high content analysis of the tumor immune microenvironment using MICS technology
    Next generation ultra high content analysis of the tumor immune...
    DATE: September 15, 2020 TIME: 08:00am PT Tumorigenesis and cancer progression are affected by the tumor immune microenvironment (TIME). The TIME not only influences the efficiency of existi...
    Speaker: Stefan Eulitz
    Sponsored By: Miltenyi Biotec
    15 2
     
     
  • SEP 08, 2020 | 11:00 PM
    Recombination, lineage-specific mutations and the emergence of SARS-CoV-2
    Recombination, lineage-specific mutations and the emergence of...
    The recent outbreak of SARS-CoV-2 underscores the need for understanding the evolutionary processes that drive the emergence and adaptation of zoonotic viruses in humans. Here, we show that...
    Speaker: Ioan Filip, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    1
    SEP 01, 2020 | 8:00 AM
    Single-cell analyses of checkpoint-inhibition-induced myocarditis: implications into mechanisms of severe immune-related adverse events
    Single-cell analyses of checkpoint-inhibition-induced myocarditis:...
    DATE: September 1, 2020 TIME: 8:00am PT, 11:00am ET Nearly half of all cancer patients are eligible to receive treatment with immune checkpoint inhibitors (ICI). Thus, preventing, identifyin...
    Speaker: Justin Balko
    Sponsored By: Thermo Fisher Scientific
    20 1
    AUG 26, 2020 | 8:00 AM
    Bio-Layer Interferometry as a strategic platform to validate covalent "proximity inducing" small molecules with synthetic tumor Immunotherapeutic applications
    Bio-Layer Interferometry as a strategic platform to validate covalent...
    DATE: August 26, 2020 TIME: 8:00 am PDT The host immune "recognition" of cancer forms the basis of modern tumor immmunotherapy, a highly targeted treatment option with the demonstr...
    Speaker: Anthony Rullo , Nilshad Salim, Ph.D.
    Sponsored By: Sartorius
    13
    JUL 29, 2020 | 5:00 PM
    Enabling 3D T-Cell, Tumoroid Invasion, and Organoid Assays Through the Incorporation of Live Cellular Imaging
    Enabling 3D T-Cell, Tumoroid Invasion, and Organoid Assays Through...
    Over the last decade the cancer research field has seen a number of advances aimed at increasing the efficacy of treatments, reducing toxic side effects, and decreasing attrition rates of dr...
    Speaker: Brad Larson
    Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
    2
    JUL 29, 2020 | 3:00 PM
    Advances and trends enabling the growth of immune-based cancer research and therapeutics
    Advances and trends enabling the growth of immune-based cancer...
    With the recent successes of immunotherapies, a fresh breeze of optimism in the fight against cancer has reinvigorated the industry. Perhaps the greatest legacy will be the realization of th...
    Speaker: David Ferrick, PhD
    Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
    3
     
     
  • JUL 29, 2020 | 12:00 PM
    Linking Cancer Metabolism to Neurodegeneration
    Linking Cancer Metabolism to Neurodegeneration
    The major function of mitochondria in cellular homeostasis has been the generation of ATP through oxidative phosphorylation. However, we have previously demonstrated that mitochondria can se...
    Speaker: Navdeep S. Chandel PhD
    Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
    3
    JUL 29, 2020 | 10:00 AM
    Metabolic control of T cell tolerance and antitumor immunity
    Metabolic control of T cell tolerance and antitumor immunity
    Coordination of immune cell metabolic programs with cell fate and state is a fundamental determinant of immune responses. Emerging evidence highlights that the interplay between immune signa...
    Speaker: Hongbo Chi, PhD
    Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
    1
    JUL 29, 2020 | 7:00 AM
    What intratumoral Tregs eat makes them strong, but vulnerable: a new metabolic intervention for cancer immunotherapy
    What intratumoral Tregs eat makes them strong, but vulnerable:...
    Metabolic reprogramming is critical for governing proper T cell immune responses, including activation, production of effector molecule, migration and differentiation. The metabolic stress T...
    Speaker: Ping-Chih Ho, PhD
    Presented at: Immuno-Oncology & Cancer Biology Virtual Conference
    2
    JUL 07, 2020 | 11:00 AM
    Comprehensive landscape of the tumor microenvironment analyzed with CyTOF® technology
    Comprehensive landscape of the tumor microenvironment analyzed...
    Immune escape mechanisms such as the induction/recruitment of immunosuppressive cells and the increased expression of various immunosuppressive molecules including PD-1/PD-1 ligands are esse...
    Speaker: Hiroyoshi Nishikawa, MD, PhD
    Presented at: Fluidigm Infectious Disease and Oncology Virtual Summit
    2
    JUL 07, 2020 | 9:30 AM
    Evaluating tumor-immune cell interactions in human lung cancer using multiparametric and spatially resolved tissue analysis
    Evaluating tumor-immune cell interactions in human lung cancer...
    ...
    Speaker: Kurt Schalper, MD, PhD
    Presented at: Fluidigm Infectious Disease and Oncology Virtual Summit
    1
     
     
  • JUL 07, 2020 | 9:00 AM
    Enhancing risk stratification in early colon cancer with TNM-I (Immune) staging: focus on stage II T4N0 patients
    Enhancing risk stratification in early colon cancer with TNM-I...
    DATE: July 07, 2020 TIME: 9:00 am PDT The widely used TNM staging system is poorly predictive of response to adjuvant chemotherapy in Stage II and III colon cancer. As a result, there is ove...
    Speaker: Jérôme Galon, Ph.D , Graham Poage, Ph.D
    Sponsored By: HalioDx
    22 14
    JUL 07, 2020 | 7:30 AM
    Deciphering T cell heterogeneity in humans through analysis of antigen-specificity
    Deciphering T cell heterogeneity in humans through analysis of...
    In line with the role of T cells as critical mediators of the adaptive immune response, recombinational and junctional diversity of the T cell receptor makes each T cell almost entirely uniq...
    Speaker: Evan Newell, PhD
    Presented at: Fluidigm Infectious Disease and Oncology Virtual Summit
    2
    JUL 07, 2020 | 6:30 AM
    Deep immunophenotyping of cancer microenvironments by Imaging Mass Cytometry™
    Deep immunophenotyping of cancer microenvironments by Imaging...
    Multiplex immunophenotyping technologies are indispensable for a deeper understanding of biological systems. Until recently, high-dimensional cellular analyses implied the loss of tissue con...
    Speaker: Noel de Miranda, PhD
    Presented at: Fluidigm Infectious Disease and Oncology Virtual Summit
    1
    JUL 07, 2020 | 6:00 AM
    Single-cell mapping of human brain cancer reveals tumor-driven education of tumor-associated leukocytes
    Single-cell mapping of human brain cancer reveals tumor-driven...
    Brain malignancies can either originate from within the CNS (gliomas) or invade from other locations in the body (metastases). A highly immunosuppressive tumor microenvironment (TME) influen...
    Speaker: Burkhard Becher, PhD
    Presented at: Fluidigm Infectious Disease and Oncology Virtual Summit
    1
    JUL 02, 2020 | 12:15 PM
    Microsatellite instability analysis for studying immunotherapy and Lynch syndrome-related cancers
    Microsatellite instability analysis for studying immunotherapy...
    Microsatellite instability (MSI) is a hypermutation phenotype that results from impaired DNA mismatch repair (MMR). The presence of high levels of MSI (MSI-H) is potentially predictive of Ly...
    Speaker: Charles Baudo, PhD
    Presented at: APJ Virtual Genetic Solutions Tour 2020
    1
     
     
  • JUN 30, 2020 | 10:00 AM
    COVID-19 Serology Assays and Cell Therapy Strategies
    COVID-19 Serology Assays and Cell Therapy Strategies
    DATE: June 30, 2020 TIME: 10:00 am PDT, 1:00 pm EDT COVID-19 is a highly pathogenic disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We have assembled a panel...
    Speaker: Fatima Amanat , Dean Lee , Lior Raviv
    Sponsored By: Thermo Fisher Scientific/Gibco
    30 1
    JUN 30, 2020 | 9:00 AM
    Quality Control for the Pharmaceutical Industry; Stage 3, Continued Verification, in the Lifecycle of Analytical Procedures
    Quality Control for the Pharmaceutical Industry; Stage 3, Continued...
    DATE: June 30, 2020 TIME: 9:00am PDT, 12:00pm EDT QC laboratories perform a critical role in demonstrating pharmaceutical products are consistently manufactured, safe, potent, and pure. At t...
    Speaker: Jane Weitzel
    Sponsored By: Sartorius
    17 1
    JUN 26, 2020 | 8:00 AM
    Next-Generation Cytogenetics: international, multi-center study of chromosomal aberrations in constitutional diseases and leukemia with Bionano genome imaging
    Next-Generation Cytogenetics: international, multi-center study...
    DATE: June 26, 2020 TIME: 8:00am PT Structural variants (SVs) are an important source of genetic variation in the human genome and they are involved in a multitude of human diseases as well...
    Speaker: Alexander Hoischen , Laila El Khattabi
    Sponsored By: Bionano
    16
    JUN 17, 2020 | 1:30 PM
    Insights into the Pathogenesis of COVID-19 as Revealed by Spatial Biology
    Insights into the Pathogenesis of COVID-19 as Revealed by Spatial...
    Understanding the complex interplay between a pathogen and the host response is important to developing effective vaccines and therapeutics. The nCounter® Analysis System and GeoMx®...
    Speaker: Joseph M. Beechem, PhD , Christopher E. Mason, PhD , Robert Schwartz, PhD
    Presented at: Coronavirus Series
    Sponsored By: NanoString Technologies
    9
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