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    Viral vector manufacturing

    Viral vectors are scientific tools used to insert genes into cells. During a process known as transduction, the desired genes are delivered into the cells after. Viral vectors can be manufactured in an organism (in vivo) or in culture (in vitro) and a variety of viruses are commonly used to transduce cells, including adenovirus, lentivirus, retrovirus, and herpes simplex virus. Viral vectors are used as targeted gene therapies and in vaccine development.

    Webinars

    • APR 12, 2023 | 8:00 AM
      Unlocking the power of AAV and LVV Analytics: Insights and strategies for optimizing viral vector purity analysis
      Unlocking the power of AAV and LVV Analytics: Insights and strategies...
      Date: April 12, 2023 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) Recombinant adeno-associated viruses (AAVs), lentiviral vectors (LVV), and adenoviru...
      Speaker: Chris Heger, Ph.D
      Sponsored By: Bio-Techne
      14
      FEB 22, 2023 | 9:00 AM
      A scalable miniature circular GenCircle™ dsDNA production system for gene and cell therapy
      A scalable miniature circular GenCircle™ dsDNA production system...
      Date: February 22, 2023 Time: 9:00am (PST), 12:00pm (EST), 6:00pm (CET) Circular plasmid DNA has traditionally been used as a stable and efficient vector for gene expression and HDR-mediated...
      Speaker: Dr. Fan Zhou, PhD
      Sponsored By: GenScript
      7
      FEB 15, 2023 | 7:00 AM
      Scattering Microscopy: Label-Free Imaging Approaches
      Scattering Microscopy: Label-Free Imaging Approaches
      Date: February 15, 2023 Time: 7:00am (PST), 10:00pm (EST), 4:00pm (CET) While not all microscopy samples can fluoresce, all can scatter light, and this scattered light can be imaged. This ha...
      Speaker: Philipp Kukura , Francesco Reina , Matthew Kose-Dunn , Phil Allen
      Sponsored By: Teledyne Photometrics
      28
      NOV 09, 2022 | 8:00 AM
      Addressing common challenges in lentiviral vector clarification using closed, automated counterflow centrifugation systems
      Addressing common challenges in lentiviral vector clarification...
      Date: November 09, 2022 Time: 8:00am (PST), 11:00am (EST), 5:00pm (CET) The field of cell and gene therapy is rapidly growing. In particular, the use of lentiviruses in CAR-T applications is...
      Speaker: Carl Dargitz , Magda Tomala
      Sponsored By: Thermo Fisher Scientific, Sartorius
      16
      JUN 16, 2022 | 7:00 AM
      High-throughput LNP-mRNA integrity profiling
      High-throughput LNP-mRNA integrity profiling
      Date: June 16, 2022 Time: 7:00am (PDT), 10:00am (EDT), 4:00pm (CEST) Lipid-based nanoparticles (LNPs) are effective non-viral vectors for delivering messenger RNA products (mRNA), most notab...
      Speaker: Jérémie Parot
      Sponsored By: SCIEX
      14
      MAY 24, 2022 | 9:00 AM
      A cGMP Compatible, Non-Viral CAR T Cell Manufacturing Process
      A cGMP Compatible, Non-Viral CAR T Cell Manufacturing Process
      Date: May 24, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) Recent breakthroughs in autologous cellular therapies have generated tremendous excitement for the industry; however, thes...
      Speaker: Andrew Mancini, Ph.D
      Sponsored By: MaxCyte®
      8
      APR 20, 2022 | 11:00 AM
      Characterization of lentiviral vectors using capillary electrophoresis platform technology
      Characterization of lentiviral vectors using capillary electrophoresis...
      Date: April 20, 2022 Time: 11:00am (PDT), 2:00pm (EDT), 8:00pm (CEST) As novel therapeutic modalities progress through development, improved analytical techniques are required to overcome co...
      Speaker: Aaron Shafer
      Sponsored By: SCIEX
      7
      APR 06, 2022 | 10:30 AM
      Panel Presentation: An Overview of Gene Therapy Manufacturing: Development through Commercial Production
      Panel Presentation: An Overview of Gene Therapy Manufacturing:...
      Learning Objectives: 1. Explain what is gene therapy is. 2. Explain what steps are involved for getting a gene therapy product to the clinic. 3. Discuss development and manufacturing process...
      Speaker: Kevin G. McGarry, Jr., PhD , Samir Acharya, PhD
      Presented at: Bioprocessing Virtual Event Series 2022
      3
      APR 06, 2022 | 5:30 AM
      Introduction to Next Generation Bioanalytics Development
      Introduction to Next Generation Bioanalytics Development
      Viral Vector gene therapy has been the focus of intense research driven by the safety profile and several clinical breakthroughs. As of March 2022, there are two viral vector gene therapies...
      Speaker: Nagarjun Kasaraneni, PhD
      Presented at: Bioprocessing Virtual Event Series 2022
      2
      DEC 08, 2021 | 7:00 AM
      Troubleshooting in bioprocessing
      Troubleshooting in bioprocessing
      Date: December 08, 2021 Time: 7:00am (PDT), 10:00am (EDT) Successful bioprocessing is complex and depends on many factors. From the selection of the expression host, media composition, the p...
      Speaker: Ines Hartmann , Eric Timmermans
      Sponsored By: Eppendorf
      12
      NOV 18, 2021 | 8:00 AM
      Methods to advance your CAR T & CAR NK cell research
      Methods to advance your CAR T & CAR NK cell research
      Date: November 18, 2021 Time: 8:00am (PDT), 11:00am (EDT) Keep ahead in CAR T and CAR NK cell research. We introduce advanced techniques for generating and characterizing engineered immune c...
      Speaker: Dr. Julia Hengst , Saskia Rösch, PhD
      Sponsored By: Miltenyi Biotec
      5
      SEP 08, 2021 | 9:00 AM
      Keynote Presentation: Development of an Affordable COVID-19 Vaccine Based on a Newcastle Disease Virus Platform
      Keynote Presentation: Development of an Affordable COVID-19 Vaccine...
      Highly efficacious vaccines against COVD-19 have been generated in a record time, and allowed a great impact in preventing severe disease due to SARS-CoV-2 infection in vaccinated individual...
      Speaker: Adolfo Garcia-Sastre, PhD
      Presented at: Microbiology Week Virtual Event Series 2021
      0
      AUG 18, 2021 | 8:00 AM
      Advanced NK cell research solutions
      Advanced NK cell research solutions
      Date: August 18, 2021 Time: 8:00am (PDT), 11:00am (EDT) Discover the tools to phenotype your NK cells and to perform functional analyses such as cellular cytotoxicity assays. From NK cell is...
      Speaker: Dr. Julia Hengst
      Sponsored By: Miltenyi Biotec
      10
      JUL 27, 2021 | 8:00 AM
      Scaling-Up Exosomes and Other Extracellular Vesicles
      Scaling-Up Exosomes and Other Extracellular Vesicles
      Date: July 27, 2021 Time: 8:00am (PDT), 11:00am (EDT) The Origin of Biopharmaceutics (Biopharma) derive from The Division of Clinical Research in the U.S. Bureau of Medicine. However, author...
      Speaker: Dr. Derek Lenz
      Sponsored By: Beckman Coulter Life Sciences
      16 3
      JUL 08, 2021 | 8:00 AM
      Applying a closed, modular, semi-automated system to CAR T cell therapy manufacturing
      Applying a closed, modular, semi-automated system to CAR T cell...
      Date: July 8, 2021 Time: 8:00am (PDT) Cell-based chimeric antigen receptor (CAR) T cell therapies have rapidly advanced in recent years, with a variety of targets in clinical research and se...
      Speaker: Yongchang Ji, PhD.
      Sponsored By: Thermo Fisher Scientific
      11 4
      JUN 03, 2021 | 12:00 PM
      Utilizing the Gibco CTS Rotea System for cell and gene therapy development
      Utilizing the Gibco CTS Rotea System for cell and gene therapy...
      DATE: June 3, 2021 TIME: 12:00pm SGT This webinar is a virtual event that focuses on utilizing the Gibco CTS Rotea System for Cell and Gene Therapy...
      Speaker: Premkumar Jayaraman, PhD , Emily Benz , Eric Dubofsky
      Sponsored By: Thermo Fisher Scientific
      5
      MAY 11, 2021 | 10:00 AM
      Secure Your Next Great Discovery
      Secure Your Next Great Discovery
      Date: May 11, 2021 Time: 10:00zm PDT Your samples are some of the most valuable assets in the laboratory. After spending countless hours on extraction and preparation, your conclusions could...
      Speaker: Paulina Kocjan , Kate Meola , Zareh Zurabyan
      Presented at: Eppendorf Planet of Knowledge - A New Dimension
      Sponsored By: Eppendorf
      8
      APR 19, 2021 | 8:00 AM
      Take the Risk out of Rotations: Understanding and Implementing BioSafety Solutions in Centrifugation
      Take the Risk out of Rotations: Understanding and Implementing...
      Date: Apri 19, 2021 Time: 8:00am PDT, 5:00pm CEST Since the inception of modern biological research, BioSafety has evolved into a critical consideration in Good Laboratory Practices (GLP). Wi...
      Speaker: Dr. Derek Lenz
      Sponsored By: Beckman Coulter Life Sciences
      5
      APR 07, 2021 | 12:00 PM
      Optimizing Transfection to Generate High-Titer AAV and Lentiviral Vectors
      Optimizing Transfection to Generate High-Titer AAV and Lentiviral...
      Recombinant adeno-associated virus (AAV) and lentiviral vectors (LV) are vehicles for direct delivery of therapeutic genes to patients' cells. In the coming years, the use of AAV and LV...
      Speaker: Sandy Tseng, PhD
      Presented at: Bioprocessing Virtual Event Series 2021
      Sponsored By: Mirus
      1
      FEB 24, 2021 | 10:00 AM
      Biosafety Enclosures and the Automated Lab: Steps for Success
      Biosafety Enclosures and the Automated Lab: Steps for Success
      DATE: February 24, 2021 TIME: 10am PST Automated lab instruments such as liquid handlers and cell sorters are increasingly common in all types of laboratories, driving fast results for labor...
      Speaker: David Wasescha , Simon Fogarty
      Sponsored By: Labconco
      15
      JAN 21, 2021 | 8:00 AM
      Critical reagent characterization for regulated bioassays accelerated by Uncle
      Critical reagent characterization for regulated bioassays accelerated...
      Date: January 21, 2021 Time: 8:00am (PST), 11:00am (EST) Today, critical reagent characterization is a key component in the overall workflow to establish robust ligand binding assays (e.g.,...
      Speaker: Ron Bowsher , Adam Kinne , Kevin Lance, Ph.D.
      Sponsored By: Unchained Labs
      6
      JAN 14, 2021 | 7:00 AM
      Cell Culture Bioprocess Scale-Up Workflow from Bench to Pilot/Production Scale using Single-Use Bioreactors
      Cell Culture Bioprocess Scale-Up Workflow from Bench to Pilot/Production...
      DATE: January 14, 2021 TIME: 7:00am PST Transferring a biologic candidate from the research and development phase to commercial production usually requires increasing the working volume...
      Speaker: Amanda Suttle , Dr. Ma Sha , Rich Mirro
      Presented at: Eppendorf Planet of Knowledge - A New Dimension
      Sponsored By: Eppendorf
      16 1
      DEC 02, 2020 | 8:00 AM
      Optimize your bioprocess - From shaker to bioreactor
      Optimize your bioprocess - From shaker to bioreactor
      DATE: December 2nd, 2020 TIME: 08:00am PDT, 11:00pm EDT Bioreactors and shakers are used to cultivate microorganisms, plant, insect, and mammalian cells in different volumes. Upscaling of pr...
      Speaker: Ines Hartmann , David Solbach
      Sponsored By: Eppendorf
      11
      SEP 17, 2020 | 8:00 AM
      Scalable Manufacturing and Nanovesicle Delivery of CRISPR-Cas9 Ribonucleoproteins Using a cGMP- Compliant Cell Engineering Platform
      Scalable Manufacturing and Nanovesicle Delivery of CRISPR-Cas9...
      DATE: September 17, 2020 TIME: 8:00am PT CRISPR-Cas9 has tremendous potential as a therapeutic tool for treating human diseases. However, prolonged expression of the nuclease and gRNA from v...
      Speaker: Peter Gee, Ph.D.
      Sponsored By: MaxCyte®
      6
    APR 12, 2023 | 8:00 AM
    Unlocking the power of AAV and LVV Analytics: Insights and strategies for optimizing viral vector purity analysis
    Unlocking the power of AAV and LVV Analytics: Insights and strategies...
    Date: April 12, 2023 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) Recombinant adeno-associated viruses (AAVs), lentiviral vectors (LVV), and adenoviru...
    Speaker: Chris Heger, Ph.D
    Sponsored By: Bio-Techne
    14
    FEB 22, 2023 | 9:00 AM
    A scalable miniature circular GenCircle™ dsDNA production system for gene and cell therapy
    A scalable miniature circular GenCircle™ dsDNA production system...
    Date: February 22, 2023 Time: 9:00am (PST), 12:00pm (EST), 6:00pm (CET) Circular plasmid DNA has traditionally been used as a stable and efficient vector for gene expression and HDR-mediated...
    Speaker: Dr. Fan Zhou, PhD
    Sponsored By: GenScript
    7
    FEB 15, 2023 | 7:00 AM
    Scattering Microscopy: Label-Free Imaging Approaches
    Scattering Microscopy: Label-Free Imaging Approaches
    Date: February 15, 2023 Time: 7:00am (PST), 10:00pm (EST), 4:00pm (CET) While not all microscopy samples can fluoresce, all can scatter light, and this scattered light can be imaged. This ha...
    Speaker: Philipp Kukura , Francesco Reina , Matthew Kose-Dunn , Phil Allen
    Sponsored By: Teledyne Photometrics
    28
    NOV 09, 2022 | 8:00 AM
    Addressing common challenges in lentiviral vector clarification using closed, automated counterflow centrifugation systems
    Addressing common challenges in lentiviral vector clarification...
    Date: November 09, 2022 Time: 8:00am (PST), 11:00am (EST), 5:00pm (CET) The field of cell and gene therapy is rapidly growing. In particular, the use of lentiviruses in CAR-T applications is...
    Speaker: Carl Dargitz , Magda Tomala
    Sponsored By: Thermo Fisher Scientific, Sartorius
    16
    JUN 16, 2022 | 7:00 AM
    High-throughput LNP-mRNA integrity profiling
    High-throughput LNP-mRNA integrity profiling
    Date: June 16, 2022 Time: 7:00am (PDT), 10:00am (EDT), 4:00pm (CEST) Lipid-based nanoparticles (LNPs) are effective non-viral vectors for delivering messenger RNA products (mRNA), most notab...
    Speaker: Jérémie Parot
    Sponsored By: SCIEX
    14
     
     
  • MAY 24, 2022 | 9:00 AM
    A cGMP Compatible, Non-Viral CAR T Cell Manufacturing Process
    A cGMP Compatible, Non-Viral CAR T Cell Manufacturing Process
    Date: May 24, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) Recent breakthroughs in autologous cellular therapies have generated tremendous excitement for the industry; however, thes...
    Speaker: Andrew Mancini, Ph.D
    Sponsored By: MaxCyte®
    8
    APR 20, 2022 | 11:00 AM
    Characterization of lentiviral vectors using capillary electrophoresis platform technology
    Characterization of lentiviral vectors using capillary electrophoresis...
    Date: April 20, 2022 Time: 11:00am (PDT), 2:00pm (EDT), 8:00pm (CEST) As novel therapeutic modalities progress through development, improved analytical techniques are required to overcome co...
    Speaker: Aaron Shafer
    Sponsored By: SCIEX
    7
    APR 06, 2022 | 10:30 AM
    Panel Presentation: An Overview of Gene Therapy Manufacturing: Development through Commercial Production
    Panel Presentation: An Overview of Gene Therapy Manufacturing:...
    Learning Objectives: 1. Explain what is gene therapy is. 2. Explain what steps are involved for getting a gene therapy product to the clinic. 3. Discuss development and manufacturing process...
    Speaker: Kevin G. McGarry, Jr., PhD , Samir Acharya, PhD
    Presented at: Bioprocessing Virtual Event Series 2022
    3
    APR 06, 2022 | 5:30 AM
    Introduction to Next Generation Bioanalytics Development
    Introduction to Next Generation Bioanalytics Development
    Viral Vector gene therapy has been the focus of intense research driven by the safety profile and several clinical breakthroughs. As of March 2022, there are two viral vector gene therapies...
    Speaker: Nagarjun Kasaraneni, PhD
    Presented at: Bioprocessing Virtual Event Series 2022
    2
    DEC 08, 2021 | 7:00 AM
    Troubleshooting in bioprocessing
    Troubleshooting in bioprocessing
    Date: December 08, 2021 Time: 7:00am (PDT), 10:00am (EDT) Successful bioprocessing is complex and depends on many factors. From the selection of the expression host, media composition, the p...
    Speaker: Ines Hartmann , Eric Timmermans
    Sponsored By: Eppendorf
    12
     
     
  • NOV 18, 2021 | 8:00 AM
    Methods to advance your CAR T & CAR NK cell research
    Methods to advance your CAR T & CAR NK cell research
    Date: November 18, 2021 Time: 8:00am (PDT), 11:00am (EDT) Keep ahead in CAR T and CAR NK cell research. We introduce advanced techniques for generating and characterizing engineered immune c...
    Speaker: Dr. Julia Hengst , Saskia Rösch, PhD
    Sponsored By: Miltenyi Biotec
    5
    SEP 08, 2021 | 9:00 AM
    Keynote Presentation: Development of an Affordable COVID-19 Vaccine Based on a Newcastle Disease Virus Platform
    Keynote Presentation: Development of an Affordable COVID-19 Vaccine...
    Highly efficacious vaccines against COVD-19 have been generated in a record time, and allowed a great impact in preventing severe disease due to SARS-CoV-2 infection in vaccinated individual...
    Speaker: Adolfo Garcia-Sastre, PhD
    Presented at: Microbiology Week Virtual Event Series 2021
    0
    AUG 18, 2021 | 8:00 AM
    Advanced NK cell research solutions
    Advanced NK cell research solutions
    Date: August 18, 2021 Time: 8:00am (PDT), 11:00am (EDT) Discover the tools to phenotype your NK cells and to perform functional analyses such as cellular cytotoxicity assays. From NK cell is...
    Speaker: Dr. Julia Hengst
    Sponsored By: Miltenyi Biotec
    10
    JUL 27, 2021 | 8:00 AM
    Scaling-Up Exosomes and Other Extracellular Vesicles
    Scaling-Up Exosomes and Other Extracellular Vesicles
    Date: July 27, 2021 Time: 8:00am (PDT), 11:00am (EDT) The Origin of Biopharmaceutics (Biopharma) derive from The Division of Clinical Research in the U.S. Bureau of Medicine. However, author...
    Speaker: Dr. Derek Lenz
    Sponsored By: Beckman Coulter Life Sciences
    16 3
    JUL 08, 2021 | 8:00 AM
    Applying a closed, modular, semi-automated system to CAR T cell therapy manufacturing
    Applying a closed, modular, semi-automated system to CAR T cell...
    Date: July 8, 2021 Time: 8:00am (PDT) Cell-based chimeric antigen receptor (CAR) T cell therapies have rapidly advanced in recent years, with a variety of targets in clinical research and se...
    Speaker: Yongchang Ji, PhD.
    Sponsored By: Thermo Fisher Scientific
    11 4
     
     
  • JUN 03, 2021 | 12:00 PM
    Utilizing the Gibco CTS Rotea System for cell and gene therapy development
    Utilizing the Gibco CTS Rotea System for cell and gene therapy...
    DATE: June 3, 2021 TIME: 12:00pm SGT This webinar is a virtual event that focuses on utilizing the Gibco CTS Rotea System for Cell and Gene Therapy...
    Speaker: Premkumar Jayaraman, PhD , Emily Benz , Eric Dubofsky
    Sponsored By: Thermo Fisher Scientific
    5
    MAY 11, 2021 | 10:00 AM
    Secure Your Next Great Discovery
    Secure Your Next Great Discovery
    Date: May 11, 2021 Time: 10:00zm PDT Your samples are some of the most valuable assets in the laboratory. After spending countless hours on extraction and preparation, your conclusions could...
    Speaker: Paulina Kocjan , Kate Meola , Zareh Zurabyan
    Presented at: Eppendorf Planet of Knowledge - A New Dimension
    Sponsored By: Eppendorf
    8
    APR 19, 2021 | 8:00 AM
    Take the Risk out of Rotations: Understanding and Implementing BioSafety Solutions in Centrifugation
    Take the Risk out of Rotations: Understanding and Implementing...
    Date: Apri 19, 2021 Time: 8:00am PDT, 5:00pm CEST Since the inception of modern biological research, BioSafety has evolved into a critical consideration in Good Laboratory Practices (GLP). Wi...
    Speaker: Dr. Derek Lenz
    Sponsored By: Beckman Coulter Life Sciences
    5
    APR 07, 2021 | 12:00 PM
    Optimizing Transfection to Generate High-Titer AAV and Lentiviral Vectors
    Optimizing Transfection to Generate High-Titer AAV and Lentiviral...
    Recombinant adeno-associated virus (AAV) and lentiviral vectors (LV) are vehicles for direct delivery of therapeutic genes to patients' cells. In the coming years, the use of AAV and LV...
    Speaker: Sandy Tseng, PhD
    Presented at: Bioprocessing Virtual Event Series 2021
    Sponsored By: Mirus
    1
    FEB 24, 2021 | 10:00 AM
    Biosafety Enclosures and the Automated Lab: Steps for Success
    Biosafety Enclosures and the Automated Lab: Steps for Success
    DATE: February 24, 2021 TIME: 10am PST Automated lab instruments such as liquid handlers and cell sorters are increasingly common in all types of laboratories, driving fast results for labor...
    Speaker: David Wasescha , Simon Fogarty
    Sponsored By: Labconco
    15
     
     
  • JAN 21, 2021 | 8:00 AM
    Critical reagent characterization for regulated bioassays accelerated by Uncle
    Critical reagent characterization for regulated bioassays accelerated...
    Date: January 21, 2021 Time: 8:00am (PST), 11:00am (EST) Today, critical reagent characterization is a key component in the overall workflow to establish robust ligand binding assays (e.g.,...
    Speaker: Ron Bowsher , Adam Kinne , Kevin Lance, Ph.D.
    Sponsored By: Unchained Labs
    6
    JAN 14, 2021 | 7:00 AM
    Cell Culture Bioprocess Scale-Up Workflow from Bench to Pilot/Production Scale using Single-Use Bioreactors
    Cell Culture Bioprocess Scale-Up Workflow from Bench to Pilot/Production...
    DATE: January 14, 2021 TIME: 7:00am PST Transferring a biologic candidate from the research and development phase to commercial production usually requires increasing the working volume...
    Speaker: Amanda Suttle , Dr. Ma Sha , Rich Mirro
    Presented at: Eppendorf Planet of Knowledge - A New Dimension
    Sponsored By: Eppendorf
    16 1
    DEC 02, 2020 | 8:00 AM
    Optimize your bioprocess - From shaker to bioreactor
    Optimize your bioprocess - From shaker to bioreactor
    DATE: December 2nd, 2020 TIME: 08:00am PDT, 11:00pm EDT Bioreactors and shakers are used to cultivate microorganisms, plant, insect, and mammalian cells in different volumes. Upscaling of pr...
    Speaker: Ines Hartmann , David Solbach
    Sponsored By: Eppendorf
    11
    SEP 17, 2020 | 8:00 AM
    Scalable Manufacturing and Nanovesicle Delivery of CRISPR-Cas9 Ribonucleoproteins Using a cGMP- Compliant Cell Engineering Platform
    Scalable Manufacturing and Nanovesicle Delivery of CRISPR-Cas9...
    DATE: September 17, 2020 TIME: 8:00am PT CRISPR-Cas9 has tremendous potential as a therapeutic tool for treating human diseases. However, prolonged expression of the nuclease and gRNA from v...
    Speaker: Peter Gee, Ph.D.
    Sponsored By: MaxCyte®
    6
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