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Viral vector manufacturing
Viral vectors are scientific tools used to insert genes into cells. During a process known as transduction, the desired genes are delivered into the cells after. Viral vectors can be manufactured in an organism (in vivo) or in culture (in vitro) and a variety of viruses are commonly used to transduce cells, including adenovirus, lentivirus, retrovirus, and herpes simplex virus. Viral vectors are used as targeted gene therapies and in vaccine development.
JUL 29, 2020 | 9:00 AM
Advances in genetic engineering have improved specificity, safety and potency of T-cell receptor (TCR) and Chimeric Antigen Receptor (CAR-T) based therapies for solid and non-solid tumours....
JUN 02, 2020 | 9:00 AM
DATE: June 2, 2020 TIME: 9:00am PT, 12:00pm ET Osmolality is a well-established parameter for upstream bioprocessing, formulation, analytical development and QC applications throughout the m...
MAY 20, 2020 | 7:30 AM
Precision medicine is the paradigm to develop treatments for patients based on molecular-targets that are effective in vivo when administered. In addition to identifying the molecular and ce...
MAY 07, 2020 | 8:00 AM
DATE: May 7, 2020 TIME: 8:00AM PDT, 11:00AM EDT With the recent explosion of cell therapy, we know more about conditions affecting cell growth than ever before. Your CO2 incubator should not...
APR 08, 2020 | 12:00 AM
Digital PCR has become the emerging technique for the sequence-specific detection and quantification of nucleic acids for various applications. During the recent years, numerous articles of...
APR 08, 2020 | 12:00 AM
There has been an increasing number of successful gene therapy clinical trials, leading to regulatory approvals of numerous gene therapy products, in particular ones based on the adeno-assoc...
APR 07, 2020 | 8:00 AM
DATE: April 7, 2020 TIME: 8:00am PT, 11:00am ET This webinar sets out to establish why quality control is key to robust, reliable, reproducible science. We will look at best practice criteri...
FEB 25, 2020 | 9:00 AM
Learn about how to generate a small scale CAR-T workflow using ThermoFisher products See detailed characterization tools that can be utilized and applied in a CAR-T workflow...
JAN 09, 2020 | 10:00 AM
Join us on January 9, 2020 for this live webinar!...
DEC 11, 2019 | 7:00 AM
DATE: December 11, 2019TIME: 7:00am PST, 10:00am EST An important part of the biopharma industry, Plasmid DNA is used as a gene-delivery vehicle for DNA vaccination and as a key...
SEP 05, 2019 | 7:00 AM
DATE: September 5, 2019TIME: 7:00am PT, 10:00am ET, 4:00pm CEST PCR (Polymerase Chain Reaction) has gone through a massive evolution since its development in 1983. Besides it...
JAN 31, 2019 | 7:30 AM
Prodrugs are harmless in their native state, as they are not targeted by human enzymes. But they can be converted into highly toxic compounds (the “drug”) by viral or bacterial en...
NOV 07, 2017 | 10:00 AM
DATE: November 7, 2017 TIME: 10:00AM PSTChimeric Antigen Receptor (CAR)-transduced T lymphocytes have demonstrated impressive clinical activity against B cell malignancies in...
JUN 28, 2017 | 7:00 AM
DATE: June 28, 2017TIME: 7:00am PT, 10am ETAs gene therapy approaches usually require large amounts of AAV vectors for clinical use, few manufacturing processes have been repo...
