SEP 27, 2017 12:00 PM PDT

CRISPR-Cas9 genome engineering: Experimental Design and Applications

Presented At Cell Biology 2017
SPONSORED BY: Horizon Discovery
C.E. CREDITS: P.A.C.E. CE | Florida CE
Speakers
  • Product Manager, Horizon Discovery
    Biography
      Danielle Folkard has been with Horizon Discovery since 2014, beginning in Technical Support and progressing into Product Management, with a focus on combining genome engineering and complex cellular models to create translational disease models. After gaining her PhD from The Institute of Food Research (now The Quadram Institute), Danielle has been enjoying applying her molecular biology background in academia to more commercial applications.

    Abstract:

    The manipulation of the genome to study disease, evaluate drug targets and to stratify patient populations is now a widely accepted concept in the field. At Horizon Discovery, genome engineering is the core of everything we do and following the breakthrough in 2013, with numerous publications into the capabilities of CRISPR-Cas9 engineering, the use and applications of this technology have grown exponentially. Our selection of cell lines and engineering capabilities allows you to bring definition to your research with genotype specific cell line models.
    In order to be successful with CRISPR-Cas9 genome engineering, there are key considerations that need to be addressed, from the cell line you want to use, to guide design and screening for the mutations of interest. In this presentation, we will discuss each stage of the experimental design and will introduce you to several cutting-edge applications of CRISPR-Cas9 including generation of reporter cell lines and the development of new variations on this technology, CRISPRa and CRISPRi.


    Show Resources
    You May Also Like
    MAY 03, 2018 11:00 AM PDT
    MAY 03, 2018 11:00 AM PDT
    DATE: May 3, 2018TIME: 11:00AM PDT, 2:00PM EDTWhile stress is one of the leading causes of neuropsychiatric disorders, the molecular underpinnings of how stress induces alterations in b...
    MAY 22, 2018 08:00 AM PDT
    C.E. CREDITS
    MAY 22, 2018 08:00 AM PDT
    DATE: May 22, 2018TIME: 08:00AM PDT The nuclear receptors pregnane X receptor (PXR) and constitutive androstane receptor (CAR) are closely related transcription factors that...
    APR 27, 2018 10:00 AM PDT
    C.E. CREDITS
    APR 27, 2018 10:00 AM PDT
    DATE: April 27, 2018TIME: 10:00am PST, 1:00pm ESTGlioblastoma (GBM) and Medulloblastoma (MB) are the most common adult and paediatric brain tumours, both of which can have devastating c...
    MAY 24, 2018 09:30 AM PDT
    C.E. CREDITS
    MAY 24, 2018 09:30 AM PDT
    DATE: May 24, 2018 TIME: 9:30PM PDT The current gold standard in in vitro pre-clinical cancer treatment screening remain cell lines,...
    AUG 15, 2018 08:00 AM PDT
    C.E. CREDITS
    AUG 15, 2018 08:00 AM PDT
    DATE: August 15, 2018TIME: 08:00AM PDT, 11:00AM EDTThe failure of current chemotherapeutic strategies in the fight against cancer can be largely attributed to the occurrence of drug res...
    JUN 29, 2018 09:00 AM PDT
    C.E. CREDITS
    JUN 29, 2018 09:00 AM PDT
    DATE: June 29, 2018TIME: 09:00AM PDT, 12:00PM EDT There is significant epidemiological evidence to suggest that the consumption of a high-broccoli diet is associated with a r...
    Loading Comments...
    Show Resources