OCT 11, 2018 6:00 AM PDT

Revealing the Hidden Landscape of Structural Variants in Cancer Genomes

Speaker

Abstract

PacBio Sequencing simultaneously provides long sequence reads, high consensus accuracy, minimal sequence bias, and methylation detection. I will highlight new advances and updates on applying PacBio sequencing in cancer research, including targeted sequencing, genome-wide structural variant detection and de novo assembly of cancer genomes. Other topics presented will include full-length RNA sequencing (Iso-Seq) for the detection of gene fusions and cancer-related transcript splice isoforms, and how high-accuracy single-molecule consensus reads (through a process called circular consensus sequencing (CCS)), a capability unique to PacBio sequencing technology, can be leveraged for high-resolution, phased minor variant analysis. 

Learning Objectives: 

1. Learn about new methods to detect larger-scale genetic variants in cancer genomes
2. Understand the utility of long-read PacBio sequencing for long-distance phasing of variants
3. Get familiar with full-length RNA-seq (Iso-Seq) for the detection of gene fusions and cancer-related transcript splice isoforms


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OCT 11, 2018 6:00 AM PDT

Revealing the Hidden Landscape of Structural Variants in Cancer Genomes


Specialty

Cancer Research

Bioinformatics

Gene Expression

Cancer Diagnostics

Molecular Genetics

Cell Culture

Flow Cytometry

Research

Adverse Drug Reaction (Adr)

Immuno-Oncology

Lab Safety

Cannabinoid Research

Dna Sequencing

Analytical Chemistry

Pcr/rt-Pcr/real-Time Pcr

Geography

North America33%

Asia33%

Europe33%

Registration Source

Website Visitors100%

Job Title

Student60%

Medical Laboratory Technician20%

Post Doc20%

Organization

Academic Institution50%

Manufacturer - Other17%

Research Institute17%

Other17%


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