Learn about the latest medical breakthroughs by participating in webinars on topics surrounding disease, prevention and treatment in accordance with the latest research in health and medicine. Updates encompass a biological, psychological and sociological understanding of health.
Inborn errors of metabolism (IEMs) are rare, devastating disorders caused by pathogenic variants in genes encoding key metabolic enzymes, with the liver playing a critical role in over 140 I...
The COVID-19 pandemic is a dramatic reminder of the problems that viral zoonoses can cause worldwide. The rapid development of vaccines and antivirals......
Multi-target screening can offer great insight into the genetic pathways in drug resistance and disease. RNAi and the fast pace of CRISPR technology development has brought sophisticated opt...
Solid phase microextraction (SPME) is a versatile, non-exhaustive sample preparation tool that has been demonstrated to be well-suited for facile and effective analysis of a broad range of c...
Current methods used to predict safety and efficacy of candidate drugs accounts for as much as 90% failure rate. Approximately 30% of drugs have failed......
Background: CDK4/6 inhibitors increase tumor immunogenicity in preclinical models of breast cancer and several trials combining CDK4/6 inhibitors and anti-PD1/PDL1 therapies are underway. Ho...
Characterization of rare cells remains a major challenge for the evaluation and understanding of key biological systems, such as circulating tumor cells (CTCs) from liquid biopsy, stem cells...
Learning Objectives: 1. Describe and discuss some of the unique aspect of in vivo studies. 2. Identify specific study practices to ensure high quality study data and animal welfare. 3. Discu...
Prostate cancers are considered immunologically ‘cold’ tumors given the very few patients who respond to checkpoint inhibitor therapy (CPI). Recently, enrichment of interferon st...
Despite the immense promise of cancer immunotherapies, significant challenges have been mounting to overcome treatment resistance and to improve efficacy. Strategies such as the combination...
This presentation explores the pharmacokinetics (PK) and pharmacodynamics (PD) of β-lactam antibiotic dosing, particularly in ICU patients. To optimize PK/PD targets, two strategies are...
Some of the earliest symptoms of Alzheimer’s disease (AD) are loss of orientation, wandering and misplacing items. One of the first regions vulnerable to AD pathology is the entorhinal...
Saliva serves as a reservoir for the upper aerodigestive tract (UADT). Saliva collection is non-invasive, convenient, and amenable to self-collection. Thus, saliva is an ideal resource for l...
Though tumor targeting using chimeric receptors (CAR) engineered to bind tumor-associated surface proteins such as CD19 in B cells have demonstrated remarkable efficacy in cancer, this thera...
Comprehensive genomic profiling (CGP) is advancing precision oncology research through simultaneous analysis of multiple biomarkers in a single next-generation sequencing (NGS) assay. In thi...
The Moonshot program was established in the UK by The Department of Health and Social Care to explore novel technologies for the detection of SARS-COV-2. Mass spectrometry was identified as...
Adjuvant discovery is largely devoted toward the development of vaccines meant to elicit prophylactic humoral immunity. While useful against infectious diseases, this mode of adaptive immuni...
The last 20 years have seen an explosion of genetic information and data. New technological advances have made it faster and less expensive to understand the human genomes but most of those...
Shantanu will be providing an overview about how predictive genomics is a powerful capability to help predict disease risk and understand drug response in order to improve health outcomes an...
Historically, nasopharyngeal sampling has been considered the gold standard for the detection of most upper respiratory tract infections, however major medical and laboratory supply chain is...
Molecular diagnostic tests are currently used for infectious disease testing due to the superior sensitivity and specificity that can be obtained. Due to the success that has been obtained w...
The global incidence of cancer is on a steady rise, with a projected annual diagnosis rate of nearly 30 million cases by 2040. Despite this alarming trend, our understanding of the intricate...
Motor coordination relies on accurate predictions that specify how the body should move in particular sensorimotor contexts. Although such predictions are thought to be stored as associative...
Infectious diseases have been a major threat to human health throughout history, causing significant economic damage worldwide. In modern medicine, quickly and accurately identifying the ger...
The inner nuclear membrane of eukaryotic cells defines many aspects of gene expression and chromatin organization. It is also therapeutically important as several diseases, termed “lam...
Inborn errors of metabolism (IEMs) are rare, devastating disorders caused by pathogenic variants in genes encoding key metabolic enzymes, with the liver playing a critical role in over 140 I...
