Learn about the latest medical breakthroughs by participating in webinars on topics surrounding disease, prevention and treatment in accordance with the latest research in health and medicine. Updates encompass a biological, psychological and sociological understanding of health.
Pancreatic ductal adenocarcinoma (PDAC) is characterized clinically by poor survival and mechanistically by KRAS- and autophagy-dependent growth. We and others previously demonstrated that i...
Ninety percent of therapeutic agents reaching clinical trial fail to reach entry to market, with safety concerns being a major cause for failures in phase I and II clinical trials. Drug-indu...
Mass spectrometry-based proteomics methods are finding increasing use in structural biology research. Beyond simple interaction networks, information about stable protein-protein, protein-li...
Comprehensive genomic profiling in clinical research studies helps to detect clinically relevant cancer driver mutations using low amount of tumor tissues within several days. Recent studies...
The application of modeling tools to better understand and control bioprocess development and manufacturing has become a hot topic within the last few years. However, what do we actually nee...
Cell therapies, including chimeric antigen receptor (CAR) T-cell therapy, are emerging as promising treatments, especially for hematological malignancies. However, many challenges remain in...
In the United States, cancer disproportionately impacts Black and African American individuals. Identifying genetic factors underlying cancer disparities has been an important research focus...
In this talk, I will discuss the development of interpretable machine learning models to test scientific hypotheses, with a specific focus on spinal motor control. Voluntary movement require...
Understanding morphogenesis is an inherently four-dimensional problem, as cells change position in space and the embryo is transformed over time. Dorsal intercalation of epidermal cells in t...
Analysis of community wastewater has been shown to be an effective method for tracking the prevalence of SARS-COV-2. Our group has developed techniques for sequencing a portion of the SARS-C...
The advent of CRISPR-Cas (Clustered regularly interspaced short palindromic repeats-CRISPR associated) makes it feasible to target/edit the genome with precision. Most of the CRSIPR-Cas syst...
In the United States, prostate cancer (PCa) is the second-leading cause of cancer death in men. Multiple observations indicate the link between prostate carcinogenesis, stress of endoplasmi...
Get to know Luminex’s xMAP® Technology all over again. For 27 years, xMAP Technology has become known as the worldwide leader in bead-based multiplexing. With the new xMAP INTELLIF...
Learning Objectives: 1. List types of sequencing and genomics methods. 2. List several methods for epigenome engineering. 3. Describe the genomic changes that occur in a spacecraft and in ast...
Given the onset of extensive school closures, we are facing widespread scenarios of stunted learning, social isolation, and most troubling, an unprecedented surge in student suicides, all wh...
Uterine leiomyosarcoma (uLMS) is a rare aggressive sarcoma of the smooth muscle layer of the uterus manifested in high local recurrence and metastatic rate. Currently, effective treatment of...
Cells in their natural environment are surrounded by a complex extracellular matrix that provides structure and functional cues to the surrounding cells. Hydrogels can be used to approximate...
As we further understand the complexity and diversity of cellular states, it is becoming necessary for a cellular engineering toolbox, consisting of molecular tools that allow control over c...
The microenvironment of many solid tumors impedes many immunotherapeutic treatments by inhibiting the effector functions of many classes of anti-tumor immune cells, including effector T cell...
There are currently several different FDA approved radiopharmaceuticals being used in both large academic and small practice settings to accurately stage and identify local and metastatic pr...
CRISPR-based diagnostics offer rapid and highly sensitive detection of disease biomarkers. Their ease of use and compatibility with lateral-flow readouts make them suitable for point-of-care...
Individuals with Lynch syndrome (LS) are prone to develop early-onset mismatch repair deficient (dMMR) colorectal- and endometrial cancers due to germline pathogenic variants (PVs) in one of...
With the health economic benefits of genetic testing clear, testing is becoming more accessible, which means constantly increasing throughput requirements for already stretched genomics......
Multiplex immunophenotyping technologies are indispensable for a deeper understanding of biological systems. Until recently, high-dimensional cellular analyses implied the loss of tissue con...
NGS technology has grown leaps and bounds in reproductive genetics field. Infertility is on the rise and with the mushrooming of so many IVF clinics in our country and increasing number of I...
Pancreatic ductal adenocarcinoma (PDAC) is characterized clinically by poor survival and mechanistically by KRAS- and autophagy-dependent growth. We and others previously demonstrated that i...
