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    Research model

    Research models are used in medical research to mimic aspects of a disease or illness that occurs in humans. Research models can include animals (in vivo models), cell lines (in vitro models), or computer-driven demonstrations (in silico models). Research models allow doctors and scientists to uncover important information that can be applied to clinical practice.

    Webinars

    • SEP 11, 2019 | 12:00 PM
      Understanding Astrovirus Pathogenesis: Who Knew Viruses Had Toxins?
      Understanding Astrovirus Pathogenesis: Who Knew Viruses Had Toxins?
      immunocompromised populations where the virus can cause systemic and even fatal infections. Indeed, we have shown that astrovirus infections are more prevalent than norovirus in our pediatric...
      Speaker: Stacey Schultz-Cherry, PhD
      Presented at: Microbiology & Immunology Virtual Event Series 2019
      5
      SEP 05, 2019 | 7:00 AM
      The bread and butter method of genomics: How to improve your (q)PCR
      The bread and butter method of genomics: How to improve your (q)PCR
      DATE: September 5, 2019TIME: 7:00am PT, 10:00am ET, 4:00pm CEST PCR (Polymerase Chain Reaction) has gone through a massive evolution since its development in 1983. Besides it...
      Speaker: Tim Schommartz, PhD
      Sponsored By: Eppendorf
      17 1
      AUG 22, 2019 | 6:00 AM
      In Vitro Screening Approaches to Estimate Human Hepatic Responses to Xenobiotic Exposures
      In Vitro Screening Approaches to Estimate Human Hepatic Responses...
      Prediction of human response to chemical exposures is the primary challenge of pharmaceutical and environmental toxicology research. The complexity of human responses to xenobiotic exposures...
      Speaker: Stephen Ferguson, PhD
      Presented at: Forensics & Toxicology 2019
      1
      AUG 15, 2019 | 9:00 AM
      Understanding and ameliorating radiation-induced damage to oligodendrocytes
      Understanding and ameliorating radiation-induced damage to oligodendrocytes
      DATE: August 15, 2019TIME: 9:00am PDT, 12:00pm EDT Radiation therapy is a critical tool for the treatment of brain tumors, however, exposure to high doses of ionizing radiation...
      Speaker: Alexandra Taraboletti, PHD
      Sponsored By: Thermo Fisher Scientific/Gibco
      6
      JUL 31, 2019 | 9:00 AM
      Choroid Plexus Epithelial Cell 2D & Modified 3D Cell Culture Model
      Choroid Plexus Epithelial Cell 2D & Modified 3D Cell Culture Model
      DATE: July 31, 2019TIME: 9:00am PT, 12:00pm ET The choroid plexus, which makes up the blood-cerebrospinal fluid barrier in the central nervous system (CNS), lines the ventricle...
      Speaker: Elizabeth Delery, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      7 1
      JUL 30, 2019 | 6:00 AM
      Overview of the new ERA Guidelines: Changes and Revisions
      Overview of the new ERA Guidelines: Changes and Revisions
      DATE: July 30, 2019TIME: 6:00am PT, 9:00am ET The current version of the EMA Guideline for the environmental risk assessment of human drugs was published in 2006. This guidance...
      Speaker: Erick Nfon, PhD
      Sponsored By: Smithers
      4
      JUN 27, 2019 | 9:00 AM
      CANCER ON A CHIP: A microfluidic 2D and 3D cell culture system for studying cellular microenvironment
      CANCER ON A CHIP: A microfluidic 2D and 3D cell culture system...
      DATE: June 27, 2019TIME: 9:00am PDT, 12:00pm EDT At present cancer research focuses on three major areas viz. cancer diagnostics, drugs development, and next-generation therapi...
      Speaker: Vivek Kamat, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      12
      JUN 20, 2019 | 1:30 PM
      Rapid Variant Modeling in a Hospital Setting
      Rapid Variant Modeling in a Hospital Setting
      Implementing precision genomic medicine in the pediatric acute care setting has several challenges. First, the diagnosis must be made quickly. Second, the determination of pathogenicity mus...
      Speaker: Matthew Bainbridge, PhD
      Presented at: Precision Medicine Virtual Event Series 2019
      1
      JUN 20, 2019 | 1:30 PM
      Single Cell CNV End-to-End Workflow to Dissect Tumor Heterogeneity
      Single Cell CNV End-to-End Workflow to Dissect Tumor Heterogeneity
      Tumor heterogeneity is a hallmark of cancer and can have significant impact on identifying drivers, including those that may be therapeutically relevant. Although, the traditional sequencing...
      Speaker: Lee Gibbs, PhD
      Presented at: Precision Medicine Virtual Event Series 2019
      1
      JUN 19, 2019 | 11:00 AM
      Selecting the right tools to build your pluripotent stem cell based disease models
      Selecting the right tools to build your pluripotent stem cell...
      DATE: June 19, 2019TIME: 11:00am PDT, 2:00pm EDT Abstract:...
      Speaker: Erik Willems, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      3
      JUN 19, 2019 | 10:00 AM
      Getting started in 3D:  Ask an Expert
      Getting started in 3D: Ask an Expert
      DATE: June 19, 2019TIME: 10:00am PDT, 1:00pm EDT As we develop new methods to create more biologically relevant models for research in understanding disease etiology and in...
      Speaker: Mark Kennedy, Ph.D. , Richard Josephson, PhD
      Sponsored By: Thermo Fisher Scientific
      6
      JUN 19, 2019 | 8:00 AM
      Exploring the genetic landscape of solid tumors using whole-genome copy number analysis
      Exploring the genetic landscape of solid tumors using whole-genome...
      DATE: June 19, 2019TIME: 8:00am PDT, 11:00am EDT Approximately 80% of all cancers are known to be affected by both somatic mutations and copy number changes. Furthermore, r...
      Speaker: Ravindra Kolhe, MD, PhD , Joanna Przybyl, PhD
      Sponsored By: Thermo Fisher Scientific - Applied Biosystems
      4
      JUN 18, 2019 | 4:00 PM
      Pluripotent stem cells:  How to raise the quality of your PSC culture
      Pluripotent stem cells: How to raise the quality of your PSC...
      DATE: June 18, 2019TIME: 7:00am PDT, 10:00 EDT, 4:00pm CET PSCs represent an important tool in a wide range of applications, including basic research, disease modeling, drug...
      Speaker: Jessica Wagener, PhD , Nadine Mellies, PhD
      Sponsored By: Eppendorf
      13
      MAY 30, 2019 | 1:30 PM
      Hybrid Tissue-Chips:  Modeling Drug Delivery and Disease with Novel Microfluidics for Living Tissue
      Hybrid Tissue-Chips: Modeling Drug Delivery and Disease with...
      Tissues in the body are wonderfully organized, with specific arrangements of cells, extracellular matrix, secreted molecules, and fluid flow that synergize that create emergent functions. How...
      Speaker: Rebecca Pompano, PhD
      Presented at: Laboratory Testing & Automation Virtual Event Series 2019
      2
      MAY 23, 2019 | 9:00 AM
      Doing More with Less: Stem Cells Regulate Their Fate by Altering Their Stiffness
      Doing More with Less: Stem Cells Regulate Their Fate by Altering...
      DATE:  May 23, 2019TIME:   9:00am PDT, 12:00pm EDT Although mesenchymal stem/stromal cells (MSCs) chondrogenic differentiation has been thoroughly investigated...
      Speaker: Melika Sarem, PhD
      Sponsored By: Thermo Fisher Scientific/Gibco
      7
      MAY 09, 2019 | 1:30 PM
      C.E. CREDITS
      The NIH Rare Disease Undiagnosed Diseases Network; Lessons Learnt and Challenges Faced in the First Four Years
      The NIH Rare Disease Undiagnosed Diseases Network; Lessons Learnt...
      In 2014, the Undiagnosed Diseases Network (UDN), which is funded by the NIH, was established as a network of seven clinical sites, two sequencing cores, and a coordinating center. Later, a ce...
      Speaker: Liz Worthey, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2019
      2
      MAY 09, 2019 | 9:00 AM
      Polygenic Risk Scores: PheWas and GWAS and Utility of Biobank Information
      Polygenic Risk Scores: PheWas and GWAS and Utility of Biobank...
      The advent of precision medicine largely depends on the creation of precise and accurate predictive tools. While most late-onset diseases are moderately to highly heritable, using genetic inf...
      Speaker: Guillaume Paré, MD, MSc, FRCPC
      Presented at: Genetics and Genomics Virtual Event Series 2019
      Sponsored By: Illumina
      2 1
      MAY 08, 2019 | 10:30 AM
      C.E. CREDITS
      Using Networks to Understand Cancer Risk
      Using Networks to Understand Cancer Risk
      One of the central tenants of biology is that our genetics—our genotype—influences the physical characteristics we manifest—our phenotype. But with more than 25,000 human ge...
      Speaker: John Quackenbush, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2019
      2
      MAY 08, 2019 | 6:00 AM
      C.E. CREDITS
      Novel DNA Methylation in Mammals
      Novel DNA Methylation in Mammals
      Genetic drivers of cancer can be dysregulated through epigenetic modifications of DNA. Although the critical role of DNA 5-methylcytosine (5mC) in the regulation of transcription is recognize...
      Speaker: Tao Wu, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2019
      2
      APR 25, 2019 | 1:30 PM
      In Vivo Models for Infectious Disease Research Through the Years
      In Vivo Models for Infectious Disease Research Through the Years
      Over the past 25 years many advances in techniques have been incorporated into infectious disease research. From genetically modified animals to advances in basic techniques that improve res...
      Speaker: Matthew Flegal, BS, SRS
      Presented at: Infectious Disease Virtual Event Series 2019
      4 1
      APR 25, 2019 | 12:00 PM
      Diagnosis and Treatment of Tuberculosis, a Case Study in Challenges and Threats Posed by Infectious Diseases
      Diagnosis and Treatment of Tuberculosis, a Case Study in Challenges...
      Tuberculosis has killed more than one billion people in the last 200 years. It is the oldest and the deadliest human pathogen, recently surpassing HIV. Its adaptation to host and drug pressur...
      Speaker: Faramarz Valafar, PhD
      Presented at: Infectious Disease Virtual Event Series 2019
      2
      APR 25, 2019 | 10:30 AM
      Advances in Point-Of-Care Testing for Infectious Diseases
      Advances in Point-Of-Care Testing for Infectious Diseases
      Point-of-care testing (POCT) is diagnostic testing at the time and place of patient care in a physician’s office, an ambulance, a mobile clinic, at home or in hospital. Rapid POC testi...
      Speaker: Krishnan Allampallam, PhD , Paul Lambotte, PhD
      Presented at: Infectious Disease Virtual Event Series 2019
      Sponsored By: Chembio
      4 1
      APR 25, 2019 | 10:30 AM
      Overcoming Complexity to Elucidate the Role of Immunoglobulin Polymorphism in the Functional Antibody Response
      Overcoming Complexity to Elucidate the Role of Immunoglobulin...
      Recent evidence indicates that the immunoglobulin (IG) gene loci reside within the most complex and variable regions of the human genome, characterized by elevated levels of single nucleotide...
      Speaker: Corey Watson, PhD
      Presented at: Infectious Disease Virtual Event Series 2019
      1
      APR 25, 2019 | 9:00 AM
      Keynote Presentation: The Next Pandemic
      Keynote Presentation: The Next Pandemic
      “Emerging infections” are those that appear suddenly or are rapidly increasing in incidence or geographic range (e.g., HIV/AIDS, Ebola, SARS, Middle East Respiratory Syndrome [MER...
      Speaker: Stephen S. Morse, PhD, FAAM, F.A.C.E.
      Presented at: Infectious Disease Virtual Event Series 2019
      6
    SEP 11, 2019 | 12:00 PM
    Understanding Astrovirus Pathogenesis: Who Knew Viruses Had Toxins?
    Understanding Astrovirus Pathogenesis: Who Knew Viruses Had Toxins?
    immunocompromised populations where the virus can cause systemic and even fatal infections. Indeed, we have shown that astrovirus infections are more prevalent than norovirus in our pediatric...
    Speaker: Stacey Schultz-Cherry, PhD
    Presented at: Microbiology & Immunology Virtual Event Series 2019
    5
    SEP 05, 2019 | 7:00 AM
    The bread and butter method of genomics: How to improve your (q)PCR
    The bread and butter method of genomics: How to improve your (q)PCR
    DATE: September 5, 2019TIME: 7:00am PT, 10:00am ET, 4:00pm CEST PCR (Polymerase Chain Reaction) has gone through a massive evolution since its development in 1983. Besides it...
    Speaker: Tim Schommartz, PhD
    Sponsored By: Eppendorf
    17 1
    AUG 22, 2019 | 6:00 AM
    In Vitro Screening Approaches to Estimate Human Hepatic Responses to Xenobiotic Exposures
    In Vitro Screening Approaches to Estimate Human Hepatic Responses...
    Prediction of human response to chemical exposures is the primary challenge of pharmaceutical and environmental toxicology research. The complexity of human responses to xenobiotic exposures...
    Speaker: Stephen Ferguson, PhD
    Presented at: Forensics & Toxicology 2019
    1
    AUG 15, 2019 | 9:00 AM
    Understanding and ameliorating radiation-induced damage to oligodendrocytes
    Understanding and ameliorating radiation-induced damage to oligodendrocytes
    DATE: August 15, 2019TIME: 9:00am PDT, 12:00pm EDT Radiation therapy is a critical tool for the treatment of brain tumors, however, exposure to high doses of ionizing radiation...
    Speaker: Alexandra Taraboletti, PHD
    Sponsored By: Thermo Fisher Scientific/Gibco
    6
    JUL 31, 2019 | 9:00 AM
    Choroid Plexus Epithelial Cell 2D & Modified 3D Cell Culture Model
    Choroid Plexus Epithelial Cell 2D & Modified 3D Cell Culture Model
    DATE: July 31, 2019TIME: 9:00am PT, 12:00pm ET The choroid plexus, which makes up the blood-cerebrospinal fluid barrier in the central nervous system (CNS), lines the ventricle...
    Speaker: Elizabeth Delery, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    7 1
     
     
  • JUL 30, 2019 | 6:00 AM
    Overview of the new ERA Guidelines: Changes and Revisions
    Overview of the new ERA Guidelines: Changes and Revisions
    DATE: July 30, 2019TIME: 6:00am PT, 9:00am ET The current version of the EMA Guideline for the environmental risk assessment of human drugs was published in 2006. This guidance...
    Speaker: Erick Nfon, PhD
    Sponsored By: Smithers
    4
    JUN 27, 2019 | 9:00 AM
    CANCER ON A CHIP: A microfluidic 2D and 3D cell culture system for studying cellular microenvironment
    CANCER ON A CHIP: A microfluidic 2D and 3D cell culture system...
    DATE: June 27, 2019TIME: 9:00am PDT, 12:00pm EDT At present cancer research focuses on three major areas viz. cancer diagnostics, drugs development, and next-generation therapi...
    Speaker: Vivek Kamat, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    12
    JUN 20, 2019 | 1:30 PM
    Rapid Variant Modeling in a Hospital Setting
    Rapid Variant Modeling in a Hospital Setting
    Implementing precision genomic medicine in the pediatric acute care setting has several challenges. First, the diagnosis must be made quickly. Second, the determination of pathogenicity mus...
    Speaker: Matthew Bainbridge, PhD
    Presented at: Precision Medicine Virtual Event Series 2019
    1
    JUN 20, 2019 | 1:30 PM
    Single Cell CNV End-to-End Workflow to Dissect Tumor Heterogeneity
    Single Cell CNV End-to-End Workflow to Dissect Tumor Heterogeneity
    Tumor heterogeneity is a hallmark of cancer and can have significant impact on identifying drivers, including those that may be therapeutically relevant. Although, the traditional sequencing...
    Speaker: Lee Gibbs, PhD
    Presented at: Precision Medicine Virtual Event Series 2019
    1
    JUN 19, 2019 | 11:00 AM
    Selecting the right tools to build your pluripotent stem cell based disease models
    Selecting the right tools to build your pluripotent stem cell...
    DATE: June 19, 2019TIME: 11:00am PDT, 2:00pm EDT Abstract:...
    Speaker: Erik Willems, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    3
     
     
  • JUN 19, 2019 | 10:00 AM
    Getting started in 3D:  Ask an Expert
    Getting started in 3D: Ask an Expert
    DATE: June 19, 2019TIME: 10:00am PDT, 1:00pm EDT As we develop new methods to create more biologically relevant models for research in understanding disease etiology and in...
    Speaker: Mark Kennedy, Ph.D. , Richard Josephson, PhD
    Sponsored By: Thermo Fisher Scientific
    6
    JUN 19, 2019 | 8:00 AM
    Exploring the genetic landscape of solid tumors using whole-genome copy number analysis
    Exploring the genetic landscape of solid tumors using whole-genome...
    DATE: June 19, 2019TIME: 8:00am PDT, 11:00am EDT Approximately 80% of all cancers are known to be affected by both somatic mutations and copy number changes. Furthermore, r...
    Speaker: Ravindra Kolhe, MD, PhD , Joanna Przybyl, PhD
    Sponsored By: Thermo Fisher Scientific - Applied Biosystems
    4
    JUN 18, 2019 | 4:00 PM
    Pluripotent stem cells:  How to raise the quality of your PSC culture
    Pluripotent stem cells: How to raise the quality of your PSC...
    DATE: June 18, 2019TIME: 7:00am PDT, 10:00 EDT, 4:00pm CET PSCs represent an important tool in a wide range of applications, including basic research, disease modeling, drug...
    Speaker: Jessica Wagener, PhD , Nadine Mellies, PhD
    Sponsored By: Eppendorf
    13
    MAY 30, 2019 | 1:30 PM
    Hybrid Tissue-Chips:  Modeling Drug Delivery and Disease with Novel Microfluidics for Living Tissue
    Hybrid Tissue-Chips: Modeling Drug Delivery and Disease with...
    Tissues in the body are wonderfully organized, with specific arrangements of cells, extracellular matrix, secreted molecules, and fluid flow that synergize that create emergent functions. How...
    Speaker: Rebecca Pompano, PhD
    Presented at: Laboratory Testing & Automation Virtual Event Series 2019
    2
    MAY 23, 2019 | 9:00 AM
    Doing More with Less: Stem Cells Regulate Their Fate by Altering Their Stiffness
    Doing More with Less: Stem Cells Regulate Their Fate by Altering...
    DATE:  May 23, 2019TIME:   9:00am PDT, 12:00pm EDT Although mesenchymal stem/stromal cells (MSCs) chondrogenic differentiation has been thoroughly investigated...
    Speaker: Melika Sarem, PhD
    Sponsored By: Thermo Fisher Scientific/Gibco
    7
     
     
  • MAY 09, 2019 | 1:30 PM
    C.E. CREDITS
    The NIH Rare Disease Undiagnosed Diseases Network; Lessons Learnt and Challenges Faced in the First Four Years
    The NIH Rare Disease Undiagnosed Diseases Network; Lessons Learnt...
    In 2014, the Undiagnosed Diseases Network (UDN), which is funded by the NIH, was established as a network of seven clinical sites, two sequencing cores, and a coordinating center. Later, a ce...
    Speaker: Liz Worthey, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2019
    2
    MAY 09, 2019 | 9:00 AM
    Polygenic Risk Scores: PheWas and GWAS and Utility of Biobank Information
    Polygenic Risk Scores: PheWas and GWAS and Utility of Biobank...
    The advent of precision medicine largely depends on the creation of precise and accurate predictive tools. While most late-onset diseases are moderately to highly heritable, using genetic inf...
    Speaker: Guillaume Paré, MD, MSc, FRCPC
    Presented at: Genetics and Genomics Virtual Event Series 2019
    Sponsored By: Illumina
    2 1
    MAY 08, 2019 | 10:30 AM
    C.E. CREDITS
    Using Networks to Understand Cancer Risk
    Using Networks to Understand Cancer Risk
    One of the central tenants of biology is that our genetics—our genotype—influences the physical characteristics we manifest—our phenotype. But with more than 25,000 human ge...
    Speaker: John Quackenbush, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2019
    2
    MAY 08, 2019 | 6:00 AM
    C.E. CREDITS
    Novel DNA Methylation in Mammals
    Novel DNA Methylation in Mammals
    Genetic drivers of cancer can be dysregulated through epigenetic modifications of DNA. Although the critical role of DNA 5-methylcytosine (5mC) in the regulation of transcription is recognize...
    Speaker: Tao Wu, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2019
    2
    APR 25, 2019 | 1:30 PM
    In Vivo Models for Infectious Disease Research Through the Years
    In Vivo Models for Infectious Disease Research Through the Years
    Over the past 25 years many advances in techniques have been incorporated into infectious disease research. From genetically modified animals to advances in basic techniques that improve res...
    Speaker: Matthew Flegal, BS, SRS
    Presented at: Infectious Disease Virtual Event Series 2019
    4 1
     
     
  • APR 25, 2019 | 12:00 PM
    Diagnosis and Treatment of Tuberculosis, a Case Study in Challenges and Threats Posed by Infectious Diseases
    Diagnosis and Treatment of Tuberculosis, a Case Study in Challenges...
    Tuberculosis has killed more than one billion people in the last 200 years. It is the oldest and the deadliest human pathogen, recently surpassing HIV. Its adaptation to host and drug pressur...
    Speaker: Faramarz Valafar, PhD
    Presented at: Infectious Disease Virtual Event Series 2019
    2
    APR 25, 2019 | 10:30 AM
    Advances in Point-Of-Care Testing for Infectious Diseases
    Advances in Point-Of-Care Testing for Infectious Diseases
    Point-of-care testing (POCT) is diagnostic testing at the time and place of patient care in a physician’s office, an ambulance, a mobile clinic, at home or in hospital. Rapid POC testi...
    Speaker: Krishnan Allampallam, PhD , Paul Lambotte, PhD
    Presented at: Infectious Disease Virtual Event Series 2019
    Sponsored By: Chembio
    4 1
    APR 25, 2019 | 10:30 AM
    Overcoming Complexity to Elucidate the Role of Immunoglobulin Polymorphism in the Functional Antibody Response
    Overcoming Complexity to Elucidate the Role of Immunoglobulin...
    Recent evidence indicates that the immunoglobulin (IG) gene loci reside within the most complex and variable regions of the human genome, characterized by elevated levels of single nucleotide...
    Speaker: Corey Watson, PhD
    Presented at: Infectious Disease Virtual Event Series 2019
    1
    APR 25, 2019 | 9:00 AM
    Keynote Presentation: The Next Pandemic
    Keynote Presentation: The Next Pandemic
    “Emerging infections” are those that appear suddenly or are rapidly increasing in incidence or geographic range (e.g., HIV/AIDS, Ebola, SARS, Middle East Respiratory Syndrome [MER...
    Speaker: Stephen S. Morse, PhD, FAAM, F.A.C.E.
    Presented at: Infectious Disease Virtual Event Series 2019
    6
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