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        MAR 01, 2023
        The Future of Cutting-Edge Genomic Technologies for Liquid Biopsy Cancer Research​
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      • Tips and tricks for successful multiplexing IHC
        JAN 31, 2023
        Tips and tricks for successful multiplexing IHC
      • Break the Bottleneck: Automate Plasmid Maxi-prep with AmMag™ Quatro
        FEB 02, 2023
        Break the Bottleneck: Automate Plasmid Maxi-prep with AmMag™ Quatro
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        FEB 08, 2023
        Visualizing Cancer Biology through Cell Culture Inserts
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        FEB 09, 2023
        A Modern Approach to Screening for Monoclonal Gammopathies using Digital Workflows
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        FEB 14, 2023
        A spatially-resolved transcriptional atlas of the murine dorsal pontine tegmentum
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      • Avoiding Common Pitfalls in Laboratory Testing for Providers and Laboratorians
        JAN 26, 2023
        Avoiding Common Pitfalls in Laboratory Testing for Providers and Laboratorians
      • Fully Automated Workflows for High Plex Multi-omic Profiling with GeoMx® Digital Spatial Profiler and BOND RX/ BOND RXm Research Stainer
        JAN 26, 2023
        Fully Automated Workflows for High Plex Multi-omic Profiling with GeoMx® Digital Spatial Profiler and BOND RX/ BOND RXm Research Stainer
      • Single-Molecule Proteomics using Protein Identification by Short-epitope Mapping
        JAN 25, 2023
        Single-Molecule Proteomics using Protein Identification by Short-epitope Mapping
      • Multiplex proteomics using proximity extension assay for identification of protein biomarkers predictive of acute graft-versus-host disease in allogeneic hematopoietic cell transplantation
        JAN 25, 2023
        Multiplex proteomics using proximity extension assay for identification of protein biomarkers predictive of acute graft-versus-host disease in allogeneic hematopoietic cell transplantation
      • The Evolution of Cervical Cancer Screening: from Paps to Precise Personalized Programs
        JAN 19, 2023
        The Evolution of Cervical Cancer Screening: from Paps to Precise Personalized Programs
      • Elucidating the composition of CRISPR-Cas12f1 complexes using mass photometry
        JAN 18, 2023
        Elucidating the composition of CRISPR-Cas12f1 complexes using mass photometry
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    ALK

    ALK, or anaplastic lymphoma kinase: a gene that tells your body how to make proteins that help cells talk to each other.

    Webinars

    • AUG 06, 2020 10:00 AM PDT
      Part III: Exploring the inhibition of Alk2 kinase and dimerization of EGFR kinase
      AUG 06, 2020 10:00 AM PDT
      Part III: Exploring the inhibition of Alk2 kinase and dimerization...
      One of the most common pathologically relevant mutated variants of ALK-2 (activin receptor-like kinase-2) has a point mutation (R206H) in its Ser/Thr kinase domain that promotes uncontrolled...
      Speaker: Kumar Ashtekar, PhD
      Presented at: 2020 Beckman Symposium
      JUL 01, 2020 2:00 PM SGT
      Operational strategies in molecular profiling of lung cancers
      JUL 01, 2020 2:00 PM SGT
      Operational strategies in molecular profiling of lung cancers
      Lung cancer management has changed over the last few years with several actionable targets being recognised and mandated in the optimal management of these patients. The biomarker ordering p...
      Speaker: Sudha Murthy, MD
      Presented at: APJ Virtual Genetic Solutions Tour 2020
      OCT 10, 2019 10:30 AM PDT
      Whole genome imaging for sensitive and accurate analysis of structural variations in cancer
      OCT 10, 2019 10:30 AM PDT
      Whole genome imaging for sensitive and accurate analysis of structural...
      Accumulation of structural variations (SVs) across the genome is a known trigger factor for oncogenesis. Structural mutations have been clearly implicated in a number of cancers, most notably...
      Speaker: Sven Bocklandt, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2019Sponsored By: Bionano
      NOV 09, 2017 1:30 PM PST
      The Development and Commercialization of Robust Circulating DNA and RNA Tests
      NOV 09, 2017 1:30 PM PST
      The Development and Commercialization of Robust Circulating DNA...
      The GeneStrat® Genomic Test is a blood-based series of ddPCR tests for DNA (EGFR, KRAS, BRAF) and multiplexed assays for RNA variants (EML4-ALK, ROS1, RET).  In this report we will u...
      Speaker: Hestia Mellert, PhD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2017
      MAY 24, 2017 12:00 PM PDT
      Adaptive Process Design, Automation & Analytics in Laboratory R&D
      MAY 24, 2017 12:00 PM PDT
      Adaptive Process Design, Automation & Analytics in Laboratory...
      R&D in life science, material science, and chemistry is burdened by fragmented and unstructured data (“spreadsheet hell”), and ambiguous or unrecorded methodological data. Thi...
      Speaker: Tim Gardner
      Presented at: Lab Automation Virtual Event Series 2017
      SEP 09, 2015 9:00 AM PDT
      WEBINAR: Clinically actionable gene fusions, CNVs and SNVs detected by NGS-based comprehensive profiling
      SEP 09, 2015 9:00 AM PDT
      WEBINAR: Clinically actionable gene fusions, CNVs and SNVs detected...
      DATE: September 9, 2015TIME: 9:00am PDT, 12:00PM EDTDriver mutations are causally implicated in tumorigenesis and disease progression, and they are defined by molecular abnormalities such as ...
      Speaker: A. John Iafrate, MD, PhD
      Sponsored By: Archer DX, Archer DX
      JUN 10, 2015 2:00 PM PDT
      Personalized medicine
      JUN 10, 2015 2:00 PM PDT
      Personalized medicine
      Matching the mutational profile of a patient's tumor with appropriate targeted agents is a goal of personalized medicine in oncology. The number of FDA-approved targeted therapies, as well as...
      Speaker: Stephen Lyle, MD, PhD
      Presented at: Cardinal Health labXchange
      SEP 16, 2014 10:00 AM PDT
      Expanded clinical research opportunities for Crizotinib identified from an analysis of over 5,000 exomes
      SEP 16, 2014 10:00 AM PDT
      Expanded clinical research opportunities for Crizotinib identified...
      Patients with chromosomal rearrangements resulting in fusion proteins are among the most responsive to published targeted therapy. For example, targeting of the EML4-ALK fusion in non-small c...
      Speaker: Sean Eddy, PhD
      Presented at: Advanced Genomics in Clinical and Translational Research - Informing end-to-end cancer drug development with bioinformatics
      SEP 16, 2014 9:30 AM PDT
      Analysis of Oncomine Knowledgebase to identify NFE2L2 pathway as a novel therapeutic opportunity in multiple cancer types
      SEP 16, 2014 9:30 AM PDT
      Analysis of Oncomine Knowledgebase to identify NFE2L2 pathway...
      Late-stage drug attrition rates in oncology remain higher than in other therapeutic areas. To reduce attrition, it is critical to identify appropriate drug targets and pre-clinical models. Th...
      Speaker: Nickolay Khazanov, PhD
      Presented at: Advanced Genomics in Clinical and Translational Research - Informing end-to-end cancer drug development with bioinformatics
      OCT 16, 2013 2:00 PM PDT
      C.E. CREDITS
      Novel therapies for ALK mutated cancers
      OCT 16, 2013 2:00 PM PDT
      Novel therapies for ALK mutated cancers
      Non Small Cell Lung Cancer (NSCLC) is one of the most significant causes of cancer-related mortality worldwide. In about 6-7% of NSCLC, rearrangements involving the Anaplastic Lymphoma Kinase...
      Speaker: Roberto Chiarle, MD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    AUG 06, 2020 10:00 AM PDT
    Part III: Exploring the inhibition of Alk2 kinase and dimerization of EGFR kinase
    AUG 06, 2020 10:00 AM PDT
    Part III: Exploring the inhibition of Alk2 kinase and dimerization...
    One of the most common pathologically relevant mutated variants of ALK-2 (activin receptor-like kinase-2) has a point mutation (R206H) in its Ser/Thr kinase domain that promotes uncontrolled...
    Speaker: Kumar Ashtekar, PhD
    Presented at: 2020 Beckman Symposium
    JUL 01, 2020 2:00 PM SGT
    Operational strategies in molecular profiling of lung cancers
    JUL 01, 2020 2:00 PM SGT
    Operational strategies in molecular profiling of lung cancers
    Lung cancer management has changed over the last few years with several actionable targets being recognised and mandated in the optimal management of these patients. The biomarker ordering p...
    Speaker: Sudha Murthy, MD
    Presented at: APJ Virtual Genetic Solutions Tour 2020
    OCT 10, 2019 10:30 AM PDT
    Whole genome imaging for sensitive and accurate analysis of structural variations in cancer
    OCT 10, 2019 10:30 AM PDT
    Whole genome imaging for sensitive and accurate analysis of structural...
    Accumulation of structural variations (SVs) across the genome is a known trigger factor for oncogenesis. Structural mutations have been clearly implicated in a number of cancers, most notably...
    Speaker: Sven Bocklandt, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2019Sponsored By: Bionano
    NOV 09, 2017 1:30 PM PST
    The Development and Commercialization of Robust Circulating DNA and RNA Tests
    NOV 09, 2017 1:30 PM PST
    The Development and Commercialization of Robust Circulating DNA...
    The GeneStrat® Genomic Test is a blood-based series of ddPCR tests for DNA (EGFR, KRAS, BRAF) and multiplexed assays for RNA variants (EML4-ALK, ROS1, RET).  In this report we will u...
    Speaker: Hestia Mellert, PhD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2017
    MAY 24, 2017 12:00 PM PDT
    Adaptive Process Design, Automation & Analytics in Laboratory R&D
    MAY 24, 2017 12:00 PM PDT
    Adaptive Process Design, Automation & Analytics in Laboratory...
    R&D in life science, material science, and chemistry is burdened by fragmented and unstructured data (“spreadsheet hell”), and ambiguous or unrecorded methodological data. Thi...
    Speaker: Tim Gardner
    Presented at: Lab Automation Virtual Event Series 2017
     
     
  • SEP 09, 2015 9:00 AM PDT
    WEBINAR: Clinically actionable gene fusions, CNVs and SNVs detected by NGS-based comprehensive profiling
    SEP 09, 2015 9:00 AM PDT
    WEBINAR: Clinically actionable gene fusions, CNVs and SNVs detected...
    DATE: September 9, 2015TIME: 9:00am PDT, 12:00PM EDTDriver mutations are causally implicated in tumorigenesis and disease progression, and they are defined by molecular abnormalities such as ...
    Speaker: A. John Iafrate, MD, PhD
    Sponsored By: Archer DX, Archer DX
    JUN 10, 2015 2:00 PM PDT
    Personalized medicine
    JUN 10, 2015 2:00 PM PDT
    Personalized medicine
    Matching the mutational profile of a patient's tumor with appropriate targeted agents is a goal of personalized medicine in oncology. The number of FDA-approved targeted therapies, as well as...
    Speaker: Stephen Lyle, MD, PhD
    Presented at: Cardinal Health labXchange
    SEP 16, 2014 10:00 AM PDT
    Expanded clinical research opportunities for Crizotinib identified from an analysis of over 5,000 exomes
    SEP 16, 2014 10:00 AM PDT
    Expanded clinical research opportunities for Crizotinib identified...
    Patients with chromosomal rearrangements resulting in fusion proteins are among the most responsive to published targeted therapy. For example, targeting of the EML4-ALK fusion in non-small c...
    Speaker: Sean Eddy, PhD
    Presented at: Advanced Genomics in Clinical and Translational Research - Informing end-to-end cancer drug development with bioinformatics
    SEP 16, 2014 9:30 AM PDT
    Analysis of Oncomine Knowledgebase to identify NFE2L2 pathway as a novel therapeutic opportunity in multiple cancer types
    SEP 16, 2014 9:30 AM PDT
    Analysis of Oncomine Knowledgebase to identify NFE2L2 pathway...
    Late-stage drug attrition rates in oncology remain higher than in other therapeutic areas. To reduce attrition, it is critical to identify appropriate drug targets and pre-clinical models. Th...
    Speaker: Nickolay Khazanov, PhD
    Presented at: Advanced Genomics in Clinical and Translational Research - Informing end-to-end cancer drug development with bioinformatics
    OCT 16, 2013 2:00 PM PDT
    C.E. CREDITS
    Novel therapies for ALK mutated cancers
    OCT 16, 2013 2:00 PM PDT
    Novel therapies for ALK mutated cancers
    Non Small Cell Lung Cancer (NSCLC) is one of the most significant causes of cancer-related mortality worldwide. In about 6-7% of NSCLC, rearrangements involving the Anaplastic Lymphoma Kinase...
    Speaker: Roberto Chiarle, MD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    Related Tags
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