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    Biological assays

    Biological assays, or bioassays, are laboratory analyses that measure the concentration of a substance. Living organisms or cells are exposed to increasing concentrations of a test substance in order to determine the impact. Biological assays are often used to access the toxicity of a compound.

    Webinars

    • OCT 26, 2020 | 11:00 AM
      Introduction to FLIM-FRET techniques
      Introduction to FLIM-FRET techniques
      This session introduces basic concepts of imaging-based high-throughput screening (HTS) and high-throughput profiling assay development. Imaging-based HTS assays are designed to evaluate a d...
      Speaker: David Andrews, PhD
      Presented at: 7th Annual Conference: SBI2 High Content
      1
      OCT 22, 2020 | 11:00 AM
      Impact of Segmentation Quality on Assay Endpoints - Deep Learning for High Content Screening
      Impact of Segmentation Quality on Assay Endpoints - Deep Learning...
      Sponsored by Cytiva....
      Speaker: Fuhui Long, PhD
      Presented at: 7th Annual Conference: SBI2 High Content
      1
      OCT 21, 2020 | 12:00 AM
      Automated consistency analysis of metabolomic and proteomic data in interlaboratory studies
      Automated consistency analysis of metabolomic and proteomic data...
      As ‘omics research advances, separations data such as chromatograms and nuclear magnetic resonance (NMR) spectra are being used as direct inputs to machine-learning algorithms ranging...
      Speaker: Dr. David A. Sheen
      Presented at: Analytical Chemistry & Separation Sciences Virtual Event Series 2020
      1
      OCT 20, 2020 | 9:00 AM
      Understanding how in vitro macrophage assays drive IO drug development forward
      Understanding how in vitro macrophage assays drive IO drug development...
      DATE: October 20th, 2020 TIME: 08:00am PT, 11:00am ET Tumor-associated macrophages (TAMs) are key cells in the tumor microenvironment (TME) with diverse immune functions that have a major in...
      Speaker: Thibaut Janss, PhD
      Sponsored By: Miltenyi Biotec
      6 1
      OCT 15, 2020 | 9:00 AM
      Evaluating the Kidney-Chip for Transporter-Mediated Drug-Drug Interactions Applications
      Evaluating the Kidney-Chip for Transporter-Mediated Drug-Drug...
      Date: October 15, 2020 Time: 9:00am (PDT), 12:00pm (EDT) Renal transporters play an important role in potential clinical drug-drug interactions (DDIs) as highlighted in the FDA, EMA and PMDA...
      Speaker: Steven Anderson, PhD , Kyung-Jin Jang, PhD , Donald McKenzie, PhD
      Sponsored By: Emulate
      9
      OCT 08, 2020 | 6:00 PM
      High-throughput biomarker profiling in immuno-oncology research & development
      High-throughput biomarker profiling in immuno-oncology research...
      Soluble cytokine biomarkers are the master regulators of cell-to-cell communication-- the means by which one cell tells another what to do or where to go. Determining the biomarker signature...
      Speaker: Jenny Koenitzer, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
      Sponsored By: MilliporeSigma
      3
      OCT 08, 2020 | 3:00 PM
      Reducing biological variance in tumor-antigen expression to standardize potency testing for immunotherapies
      Reducing biological variance in tumor-antigen expression to standardize...
      The continued rapid expansion of immunotherapies, including both in vivo and ex vivo therapeutics, has driven the development and adoption of novel tools to study, asses and understand these...
      Speaker: Benjamin Borgo, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
      Sponsored By: MilliporeSigma
      1
      OCT 08, 2020 | 10:30 AM
      Keynote Presentation: Principles of Effective Method Development in Pathobiology Research.
      Keynote Presentation: Principles of Effective Method Development...
      Immunohistochemistry (IHC) is used to determine spatial relationships where we can identify the localization of target proteins in specific regions and cells of a tissue. IHC has been the go...
      Speaker: Vivian Barry, MS
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
      Sponsored By: Roche Diagnostics
      1
      OCT 08, 2020 | 9:00 AM
      The Spatiotemporal Organization, Dynamics, and Function of Virus Replication Centers during Murine Polyomavirus Infection
      The Spatiotemporal Organization, Dynamics, and Function of Virus...
      Date: October 8, 2020 Time: 9:00am (PTD), 12:00pm (EDT), 5:00pm (GMT) Small DNA viruses require both host DNA replication and repair factors for their replication. The host cell replication...
      Speaker: Douglas Peters, PhD , Alan Mullan, PhD
      Sponsored By: Andor
      8
      OCT 08, 2020 | 7:00 AM
      Protect your cells with proper pipetting - How liquid handling influences your cell culture work
      Protect your cells with proper pipetting - How liquid handling...
      DATE: October 8, 2020 TIME: 7:00am PDT, 10:00am EDT, 4:00pm CEST How often do you pipette in your cell culture lab every day? Usually, we do it so often that we tend stop thinking about ho...
      Speaker: Nadine Mellies, PhD , Jessica Wagener, PhD
      Sponsored By: Eppendorf
      33 5
      SEP 30, 2020 | 10:30 AM
      Straightforward CRISPR knockout: Leveraging predesigned synthetic sgRNAs for highly functional and specific gene knockout
      Straightforward CRISPR knockout: Leveraging predesigned synthetic...
      CRISPR-based genome editing has accelerated biological research and holds great potential for studying and treating human diseases. The CRISPR-Cas9 system requires a Cas9 nuclease and a guid...
      Speaker: James Goldmeyer, PhD
      Presented at: CRISPR Virtual Event Series 2020
      Sponsored By: Horizon Discovery
      3 1
      SEP 30, 2020 | 12:00 AM
      CRISPR/Cas9 as a tool to model and study cancer - insights and lessons learned
      CRISPR/Cas9 as a tool to model and study cancer - insights and...
      Combinatorial inhibition of effector and feedback pathways is a promising treatment strategy for KRAS mutant cancers. However, the particular pathways that should be targeted to optimize the...
      Speaker: Grace R. Anderson, PhD
      Presented at: CRISPR Virtual Event Series 2020
      2
      SEP 23, 2020 | 4:30 PM
      Anatomy of a nucleic acid sample preparation
      Anatomy of a nucleic acid sample preparation
      There are many methods of nucleic acid isolation. Each technology offers different approaches of purification of the template. However, it is important to control carry over of “proces...
      Speaker: Katherine Mechling
      Presented at: Cell Biology Virtual Event Series 2020
      Sponsored By: MilliporeSigma
      2 1
      SEP 23, 2020 | 3:00 PM
      Beyond the Culture Flask: How Membrane- and Microfluidic-based Platforms can create more Physiologically Relevant Tissue Culture Systems
      Beyond the Culture Flask: How Membrane- and Microfluidic-based...
      For more than a century, breakthroughs in biological sciences have relied on the ability to study cells outside of respective organisms. While majority of cell culturing is still performed u...
      Speaker: Jun Park, PhD
      Presented at: Cell Biology Virtual Event Series 2020
      Sponsored By: MilliporeSigma
      1
      SEP 23, 2020 | 12:00 PM
      Keynote Presentation: Sorting out the mechanisms of endocytic recycling
      Keynote Presentation: Sorting out the mechanisms of endocytic...
      Extracellular ligands bind to receptors on the cell surface leading to receptor internalization. Once internalized into small vesicles, the vesicles fuse with an organelle known as the sorti...
      Speaker: Steve Caplan, PhD
      Presented at: Cell Biology Virtual Event Series 2020
      1
      SEP 23, 2020 | 10:30 AM
      iPSC- and patient- derived intestinal organoids for gastrointestinal research
      iPSC- and patient- derived intestinal organoids for gastrointestinal...
      Intestinal organoids are self-organizing, 3D structures derived from either pluripotent stem cells or from primary tissues with the abiltiy to recapitulate some of the spatial architecture a...
      Speaker: Kevin Su
      Presented at: Cell Biology Virtual Event Series 2020
      Sponsored By: MilliporeSigma
      2
      SEP 23, 2020 | 7:30 AM
      Cell Culture Troubleshooting Tips and Tricks
      Cell Culture Troubleshooting Tips and Tricks
      Cell culture continues to be a critical tool for most life science research and applications. From HeLa to iPSCs and 3D to organoids, culture methods have become more advanced and techniques...
      Speaker: Marina Wiklander, PhD
      Presented at: Cell Biology Virtual Event Series 2020
      Sponsored By: MilliporeSigma
      6
      SEP 23, 2020 | 12:00 AM
      GeoMx Digital Spatial Profiling read-out for Next-Generation Sequencers with the Cancer Transcriptome Atlas (CTA)
      GeoMx Digital Spatial Profiling read-out for Next-Generation Sequencers...
      GeoMx Digital Spatial Profiling Technology! The GeoMx Digital Spatial Profiler (DSP) is a novel platform developed by NanoString. This leading digital technology offers multiplexed measureme...
      Speaker: Kit Fuhrman
      Presented at: Cell Biology Virtual Event Series 2020
      1
      SEP 23, 2020 | 12:00 AM
      Extracellular Vesicles and Chronic Kidney Disease
      Extracellular Vesicles and Chronic Kidney Disease
      Chronic kidney disease (CKD) is a major public health threat, affecting 11-15% of the U.S. population alone. Currently, there are no effective therapies to cure CKD. Drug therapies are not p...
      Speaker: Sargis Sedrakyan, PhD
      Presented at: Cell Biology Virtual Event Series 2020
      1
      SEP 22, 2020 | 9:00 AM
      Mitigating risks and optimizing security of supply in diagnostics
      Mitigating risks and optimizing security of supply in diagnostics
      DATE: September 10, 2020 TIME: 8:00am PDT, 11:00am EDT...
      Speaker: David Raw
      Sponsored By: Cytiva
      8
      SEP 17, 2020 | 1:30 PM
      Decoding the Variance in Intracellular Organization in Human Stem Cells
      Decoding the Variance in Intracellular Organization in Human Stem...
      The Allen Institute for Cell Science is generating a state space of stem cell signatures. The goal is to understand cell organization, identify cell states, and elucidate how cells transitio...
      Speaker: Susanne Rafelski, PhD
      Presented at: 7th Annual Conference: SBI2 High Content
      1
      SEP 16, 2020 | 9:00 AM
      Deep multi-omic phenotyping of biospecimens for immuno-oncology applications
      Deep multi-omic phenotyping of biospecimens for immuno-oncology...
      Date: September 16, 2020 Time: 9:00am PTD, 12:00pm EDT Harnessing the power of the host immune system to treat diseases has been transformational in patient care. Physiologically relevant ce...
      Speaker: Dr. Shawn Fahl
      Sponsored By: Miltenyi Biotec
      11
      SEP 10, 2020 | 9:00 AM
      An Insider's Look: How One Parameter Can Optimize Key Phases of Bioprocessing Workflows
      An Insider's Look: How One Parameter Can Optimize Key Phases of...
      Date: September 10, 2020 Time: 9:00am (PDT), 12:00pm (EDT) Osmolality testing is relevant throughout the entire bioprocessing workflow. As customers look to refine mAb and gene therapy workf...
      Speaker: Tara Barreira , Kristeena Wright
      Sponsored By: Advanced Instruments
      7
      SEP 10, 2020 | 12:00 AM
      Visualizing viral replication of oncogenic human herpesviruses
      Visualizing viral replication of oncogenic human herpesviruses
      Viruses are the causative agents of approximately 12% of human cancers. The most recently discovered herpesvirus, Kaposi’s sarcoma herpesvirus (KSHV) is known to cause three human canc...
      Speaker: Lindsey M. Costantini, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      1
    OCT 26, 2020 | 11:00 AM
    Introduction to FLIM-FRET techniques
    Introduction to FLIM-FRET techniques
    This session introduces basic concepts of imaging-based high-throughput screening (HTS) and high-throughput profiling assay development. Imaging-based HTS assays are designed to evaluate a d...
    Speaker: David Andrews, PhD
    Presented at: 7th Annual Conference: SBI2 High Content
    1
    OCT 22, 2020 | 11:00 AM
    Impact of Segmentation Quality on Assay Endpoints - Deep Learning for High Content Screening
    Impact of Segmentation Quality on Assay Endpoints - Deep Learning...
    Sponsored by Cytiva....
    Speaker: Fuhui Long, PhD
    Presented at: 7th Annual Conference: SBI2 High Content
    1
    OCT 21, 2020 | 12:00 AM
    Automated consistency analysis of metabolomic and proteomic data in interlaboratory studies
    Automated consistency analysis of metabolomic and proteomic data...
    As ‘omics research advances, separations data such as chromatograms and nuclear magnetic resonance (NMR) spectra are being used as direct inputs to machine-learning algorithms ranging...
    Speaker: Dr. David A. Sheen
    Presented at: Analytical Chemistry & Separation Sciences Virtual Event Series 2020
    1
    OCT 20, 2020 | 9:00 AM
    Understanding how in vitro macrophage assays drive IO drug development forward
    Understanding how in vitro macrophage assays drive IO drug development...
    DATE: October 20th, 2020 TIME: 08:00am PT, 11:00am ET Tumor-associated macrophages (TAMs) are key cells in the tumor microenvironment (TME) with diverse immune functions that have a major in...
    Speaker: Thibaut Janss, PhD
    Sponsored By: Miltenyi Biotec
    6 1
    OCT 15, 2020 | 9:00 AM
    Evaluating the Kidney-Chip for Transporter-Mediated Drug-Drug Interactions Applications
    Evaluating the Kidney-Chip for Transporter-Mediated Drug-Drug...
    Date: October 15, 2020 Time: 9:00am (PDT), 12:00pm (EDT) Renal transporters play an important role in potential clinical drug-drug interactions (DDIs) as highlighted in the FDA, EMA and PMDA...
    Speaker: Steven Anderson, PhD , Kyung-Jin Jang, PhD , Donald McKenzie, PhD
    Sponsored By: Emulate
    9
     
     
  • OCT 08, 2020 | 6:00 PM
    High-throughput biomarker profiling in immuno-oncology research & development
    High-throughput biomarker profiling in immuno-oncology research...
    Soluble cytokine biomarkers are the master regulators of cell-to-cell communication-- the means by which one cell tells another what to do or where to go. Determining the biomarker signature...
    Speaker: Jenny Koenitzer, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
    Sponsored By: MilliporeSigma
    3
    OCT 08, 2020 | 3:00 PM
    Reducing biological variance in tumor-antigen expression to standardize potency testing for immunotherapies
    Reducing biological variance in tumor-antigen expression to standardize...
    The continued rapid expansion of immunotherapies, including both in vivo and ex vivo therapeutics, has driven the development and adoption of novel tools to study, asses and understand these...
    Speaker: Benjamin Borgo, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
    Sponsored By: MilliporeSigma
    1
    OCT 08, 2020 | 10:30 AM
    Keynote Presentation: Principles of Effective Method Development in Pathobiology Research.
    Keynote Presentation: Principles of Effective Method Development...
    Immunohistochemistry (IHC) is used to determine spatial relationships where we can identify the localization of target proteins in specific regions and cells of a tissue. IHC has been the go...
    Speaker: Vivian Barry, MS
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
    Sponsored By: Roche Diagnostics
    1
    OCT 08, 2020 | 9:00 AM
    The Spatiotemporal Organization, Dynamics, and Function of Virus Replication Centers during Murine Polyomavirus Infection
    The Spatiotemporal Organization, Dynamics, and Function of Virus...
    Date: October 8, 2020 Time: 9:00am (PTD), 12:00pm (EDT), 5:00pm (GMT) Small DNA viruses require both host DNA replication and repair factors for their replication. The host cell replication...
    Speaker: Douglas Peters, PhD , Alan Mullan, PhD
    Sponsored By: Andor
    8
    OCT 08, 2020 | 7:00 AM
    Protect your cells with proper pipetting - How liquid handling influences your cell culture work
    Protect your cells with proper pipetting - How liquid handling...
    DATE: October 8, 2020 TIME: 7:00am PDT, 10:00am EDT, 4:00pm CEST How often do you pipette in your cell culture lab every day? Usually, we do it so often that we tend stop thinking about ho...
    Speaker: Nadine Mellies, PhD , Jessica Wagener, PhD
    Sponsored By: Eppendorf
    33 5
     
     
  • SEP 30, 2020 | 10:30 AM
    Straightforward CRISPR knockout: Leveraging predesigned synthetic sgRNAs for highly functional and specific gene knockout
    Straightforward CRISPR knockout: Leveraging predesigned synthetic...
    CRISPR-based genome editing has accelerated biological research and holds great potential for studying and treating human diseases. The CRISPR-Cas9 system requires a Cas9 nuclease and a guid...
    Speaker: James Goldmeyer, PhD
    Presented at: CRISPR Virtual Event Series 2020
    Sponsored By: Horizon Discovery
    3 1
    SEP 30, 2020 | 12:00 AM
    CRISPR/Cas9 as a tool to model and study cancer - insights and lessons learned
    CRISPR/Cas9 as a tool to model and study cancer - insights and...
    Combinatorial inhibition of effector and feedback pathways is a promising treatment strategy for KRAS mutant cancers. However, the particular pathways that should be targeted to optimize the...
    Speaker: Grace R. Anderson, PhD
    Presented at: CRISPR Virtual Event Series 2020
    2
    SEP 23, 2020 | 4:30 PM
    Anatomy of a nucleic acid sample preparation
    Anatomy of a nucleic acid sample preparation
    There are many methods of nucleic acid isolation. Each technology offers different approaches of purification of the template. However, it is important to control carry over of “proces...
    Speaker: Katherine Mechling
    Presented at: Cell Biology Virtual Event Series 2020
    Sponsored By: MilliporeSigma
    2 1
    SEP 23, 2020 | 3:00 PM
    Beyond the Culture Flask: How Membrane- and Microfluidic-based Platforms can create more Physiologically Relevant Tissue Culture Systems
    Beyond the Culture Flask: How Membrane- and Microfluidic-based...
    For more than a century, breakthroughs in biological sciences have relied on the ability to study cells outside of respective organisms. While majority of cell culturing is still performed u...
    Speaker: Jun Park, PhD
    Presented at: Cell Biology Virtual Event Series 2020
    Sponsored By: MilliporeSigma
    1
    SEP 23, 2020 | 12:00 PM
    Keynote Presentation: Sorting out the mechanisms of endocytic recycling
    Keynote Presentation: Sorting out the mechanisms of endocytic...
    Extracellular ligands bind to receptors on the cell surface leading to receptor internalization. Once internalized into small vesicles, the vesicles fuse with an organelle known as the sorti...
    Speaker: Steve Caplan, PhD
    Presented at: Cell Biology Virtual Event Series 2020
    1
     
     
  • SEP 23, 2020 | 10:30 AM
    iPSC- and patient- derived intestinal organoids for gastrointestinal research
    iPSC- and patient- derived intestinal organoids for gastrointestinal...
    Intestinal organoids are self-organizing, 3D structures derived from either pluripotent stem cells or from primary tissues with the abiltiy to recapitulate some of the spatial architecture a...
    Speaker: Kevin Su
    Presented at: Cell Biology Virtual Event Series 2020
    Sponsored By: MilliporeSigma
    2
    SEP 23, 2020 | 7:30 AM
    Cell Culture Troubleshooting Tips and Tricks
    Cell Culture Troubleshooting Tips and Tricks
    Cell culture continues to be a critical tool for most life science research and applications. From HeLa to iPSCs and 3D to organoids, culture methods have become more advanced and techniques...
    Speaker: Marina Wiklander, PhD
    Presented at: Cell Biology Virtual Event Series 2020
    Sponsored By: MilliporeSigma
    6
    SEP 23, 2020 | 12:00 AM
    GeoMx Digital Spatial Profiling read-out for Next-Generation Sequencers with the Cancer Transcriptome Atlas (CTA)
    GeoMx Digital Spatial Profiling read-out for Next-Generation Sequencers...
    GeoMx Digital Spatial Profiling Technology! The GeoMx Digital Spatial Profiler (DSP) is a novel platform developed by NanoString. This leading digital technology offers multiplexed measureme...
    Speaker: Kit Fuhrman
    Presented at: Cell Biology Virtual Event Series 2020
    1
    SEP 23, 2020 | 12:00 AM
    Extracellular Vesicles and Chronic Kidney Disease
    Extracellular Vesicles and Chronic Kidney Disease
    Chronic kidney disease (CKD) is a major public health threat, affecting 11-15% of the U.S. population alone. Currently, there are no effective therapies to cure CKD. Drug therapies are not p...
    Speaker: Sargis Sedrakyan, PhD
    Presented at: Cell Biology Virtual Event Series 2020
    1
    SEP 22, 2020 | 9:00 AM
    Mitigating risks and optimizing security of supply in diagnostics
    Mitigating risks and optimizing security of supply in diagnostics
    DATE: September 10, 2020 TIME: 8:00am PDT, 11:00am EDT...
    Speaker: David Raw
    Sponsored By: Cytiva
    8
     
     
  • SEP 17, 2020 | 1:30 PM
    Decoding the Variance in Intracellular Organization in Human Stem Cells
    Decoding the Variance in Intracellular Organization in Human Stem...
    The Allen Institute for Cell Science is generating a state space of stem cell signatures. The goal is to understand cell organization, identify cell states, and elucidate how cells transitio...
    Speaker: Susanne Rafelski, PhD
    Presented at: 7th Annual Conference: SBI2 High Content
    1
    SEP 16, 2020 | 9:00 AM
    Deep multi-omic phenotyping of biospecimens for immuno-oncology applications
    Deep multi-omic phenotyping of biospecimens for immuno-oncology...
    Date: September 16, 2020 Time: 9:00am PTD, 12:00pm EDT Harnessing the power of the host immune system to treat diseases has been transformational in patient care. Physiologically relevant ce...
    Speaker: Dr. Shawn Fahl
    Sponsored By: Miltenyi Biotec
    11
    SEP 10, 2020 | 9:00 AM
    An Insider's Look: How One Parameter Can Optimize Key Phases of Bioprocessing Workflows
    An Insider's Look: How One Parameter Can Optimize Key Phases of...
    Date: September 10, 2020 Time: 9:00am (PDT), 12:00pm (EDT) Osmolality testing is relevant throughout the entire bioprocessing workflow. As customers look to refine mAb and gene therapy workf...
    Speaker: Tara Barreira , Kristeena Wright
    Sponsored By: Advanced Instruments
    7
    SEP 10, 2020 | 12:00 AM
    Visualizing viral replication of oncogenic human herpesviruses
    Visualizing viral replication of oncogenic human herpesviruses
    Viruses are the causative agents of approximately 12% of human cancers. The most recently discovered herpesvirus, Kaposi’s sarcoma herpesvirus (KSHV) is known to cause three human canc...
    Speaker: Lindsey M. Costantini, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
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