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    Cancer Molecular Biology

    Molecular biology plays an important role in the diagnosis and treatment of cancer. On a biological level, the development of cancer is characterized by the acquisition of genetic mutations which cause abnormal cell growth, eventually resulting in malignant disease. Understanding how molecular damage can cause these cancer-driving mutations can help design optimal treatment regimens

    Webinars

    • NOV 12, 2020 | 1:30 PM
      Covid-19 Testing and the role of Antigen assays today and moving forward
      Covid-19 Testing and the role of Antigen assays today and moving...
      Today's presentation will cover the following topics from the perspective of a NYC based Laboratory: What have we learned year to date about CoV-2 and specifically how diagnostic testing...
      Speaker: Vincent Streva, PhD
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2020
      Sponsored By: Diasorin
      1
      November 12, 2020 11:00 AM PST | 6:00 PM GMT
      Q&A Session (In the RoundTable Room)
      Q&A Session (In the RoundTable Room)
      Visit the RoundTable Room to participate in live Q&A with all the speakers!...
      Speaker: Charalambos C. Solomides, MD , Sara Eglitis, MS, QIHC , Faruk Erdem Kombak, MD , Srabani Bhaumik, PhD , Nelson Alexander, PhD
      Presented at: DISCOVERY Global User Symposium
      1
      November 12, 2020 10:00 AM PST | 5:00 PM GMT
      Representative sampling to address tumor heterogeneity
      Representative sampling to address tumor heterogeneity
      Ensuring that clinical tests are not affected by tumor heterogeneity requires a sampling methodology that captures the genomic, proteomic, and cellular diversity of entire solid tumors. Howe...
      Speaker: Nelson Alexander, PhD
      Presented at: DISCOVERY Global User Symposium
      2
      NOV 12, 2020 | 10:00 AM
      FcRn Affinity Column Chromatography for Therapeutic mAb Characterization
      FcRn Affinity Column Chromatography for Therapeutic mAb Characterization
      Date: November 12, 2020 Time: 10:00am (PST), 1:00pm (EST) Fc receptor based affinity chromatography is a new emerging field of Fc functionality analytics. FcRn affinity columns separate anti...
      Speaker: Tilman Schlothauer, Ph.D
      Sponsored By: Roche CustomBiotech
      3
      NOV 12, 2020 | 9:00 AM
      Back to Work, School, and Life: Utility of COVID-19 Testing to Help Communities Restore Normality
      Back to Work, School, and Life: Utility of COVID-19 Testing to...
      Testing volumes need to increase by orders of magnitude in order to restore communities back to normality. This workshop focuses on solutions that equip laboratories to participate in expand...
      Speaker: Dr. Jared R. Auclair , Frank Ong, MD, CPI, CCRP
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2020
      Sponsored By: Thermo Fisher Scientific
      5
      NOV 12, 2020 | 7:00 AM
      Cell Sorting for Multiple Applications - How to Optimize your Sort Setup
      Cell Sorting for Multiple Applications - How to Optimize your...
      Date: November 12, 2020 Time: 7:00am (PST), 10:00am (EST), 3:00pm (BST), 4:00pm (CET) Cell sorting is used for a wide range of applications, from profiling immune subsets to sorting cancer c...
      Speaker: Deena Soni, PhD , Miro Koulnis, PhD
      Sponsored By: Sony Biotechnology
      4
      NOV 12, 2020 | 12:00 AM
      Clinical utility of concussion injury biomarkers
      Clinical utility of concussion injury biomarkers
      Cases of traumatic brain injury (TBI) have been steadily rising over the past decade with most common causes of injury observed among participants in contact sports, combat military personne...
      Speaker: Paul R. Johnson, PhD, MT(ASCP), DABCC, FAACC
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2020
      1
      NOV 12, 2020 | 12:00 AM
      Principles of Effective Method Development in Pathobiology Research
      Principles of Effective Method Development in Pathobiology Research
      Immunohistochemistry (IHC) is used to determine spatial relationships where we can identify the localization of target proteins in specific regions and cells of a tissue. IHC has been the go...
      Speaker: Vivian Barry, MS
      Presented at: DISCOVERY Global User Symposium
      2
      NOV 12, 2020 | 12:00 AM
      How Artificial Intelligence can facilitate the use of cardiac biomarkers?
      How Artificial Intelligence can facilitate the use of cardiac...
      Biomarkers play a vital role in disease detection and treatment follow-up. It is important to note that the diseases in the early stage are typically treated with the greatest probability of...
      Speaker: Dr. Pradeep Kumar Dabla
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2020
      2
      NOV 05, 2020 | 7:00 AM
      Stem cell derived exosome production in stirred-tank bioreactors
      Stem cell derived exosome production in stirred-tank bioreactors
      DATE: Date needed, 2020 TIME: Time needed Exosomes are a population of naturally occurring mobile, membrane-limited, 30 – 100 nm in diameter, extracellular vesicles containing a large...
      Speaker: Jorge Escobar , Aurélie Tacheny
      Presented at: Eppendorf Planet of Knowledge - A New Dimension
      Sponsored By: Eppendorf
      12
      OCT 29, 2020 | 6:00 AM
      Single-cell sequencing to investigate epigenetic mechanisms in inflammatory lymphocytes
      Single-cell sequencing to investigate epigenetic mechanisms in...
      Date: October 29, 2020 Time: 6:00am (PDT), 9:00am (EDT), Chronic inflammation can occur as a result of a combination of genetic predispositions and environmental factors. Epigenetic modifica...
      Speaker: Thomas Ayers, Ph.D. , Pawel Zajac, Ph.D. , Dr. Adam Cribbs
      Sponsored By: Illumina, Dolomite Bio
      15
      OCT 22, 2020 | 12:25 PM
      Clinical impact of Next-Generation Sequencing (NGS) Testing: A hematopathologist's perspective
      Clinical impact of Next-Generation Sequencing (NGS) Testing: A...
      Myeloid neoplasms represent a highly heterogeneous group of diseases that encompass myeloproliferative, myelodysplastic (myeloproliferative/myelodysplastic) processes and acute myeloid leuke...
      Speaker: Megan S. Lim, MD, PhD
      Presented at: OncomineWorld 2022: A Virtual NGS Education Meeting
      0
      OCT 22, 2020 | 12:25 PM
      Clinical impact of Next-Generation Sequencing (NGS) Testing: A hematopathologist's perspective
      Clinical impact of Next-Generation Sequencing (NGS) Testing: A...
      Myeloid neoplasms represent a highly heterogeneous group of diseases that encompass myeloproliferative, myelodysplastic (myeloproliferative/myelodysplastic) processes and acute myeloid leuke...
      Speaker: Megan S. Lim, MD, PhD
      Presented at: OncomineWorld Autumn: A virtual NGS education meeting
      2
      OCT 22, 2020 | 8:00 AM
      Driving lab efficiency with PCR power
      Driving lab efficiency with PCR power
      Abstract: Detection and/or amplification of target DNA sequences by polymerase chain reaction (PCR) is a prevalent method in molecular biology. PCR has a broad range of applications, includi...
      Speaker: Kyle Hondorp , Marija Navickaitė
      Sponsored By: Thermo Fisher Scientific
      150 2
      OCT 22, 2020 | 7:20 AM
      NGS evolution in Solid Tumours, from S5-XL to Genexus
      NGS evolution in Solid Tumours, from S5-XL to Genexus
      During the presentation, Dr. Hernandez-Losa will describe the experience in the Department of Pathology using NGS with S5-xl in different translational projects in solid tumors. Additionally...
      Speaker: Javier Hernandez-Losa, PhD
      Presented at: OncomineWorld 2022: A Virtual NGS Education Meeting
      0
      OCT 22, 2020 | 7:20 AM
      NGS evolution in Solid Tumours, from S5-XL to Genexus
      NGS evolution in Solid Tumours, from S5-XL to Genexus
      During the presentation, Dr. Hernandez-Losa will describe the experience in the Department of Pathology using NGS with S5-xl in different translational projects in solid tumors. Additionally...
      Speaker: Javier Hernandez-Losa, PhD
      Presented at: OncomineWorld Autumn: A virtual NGS education meeting
      1
      OCT 21, 2020 | 10:35 PM
      Latest Developments with the Genexus System
      Latest Developments with the Genexus System
      The treatment of cancer has remarkably improved because of increased knowledge of the molecular abnormalities that drive human cancer growth. This has led to the development of ever more eff...
      Speaker: Dr. Jose Luis Costa
      Presented at: OncomineWorld 2022: A Virtual NGS Education Meeting
      0
      OCT 21, 2020 | 10:35 PM
      Latest Developments with the Genexus System
      Latest Developments with the Genexus System
      The treatment of cancer has remarkably improved because of increased knowledge of the molecular abnormalities that drive human cancer growth. This has led to the development of ever more eff...
      Speaker: Dr. Jose Luis Costa
      Presented at: OncomineWorld Autumn: A virtual NGS education meeting
      1
      OCT 20, 2020 | 9:00 AM
      Understanding how in vitro macrophage assays drive IO drug development forward
      Understanding how in vitro macrophage assays drive IO drug development...
      DATE: October 20th, 2020 TIME: 08:00am PT, 11:00am ET Tumor-associated macrophages (TAMs) are key cells in the tumor microenvironment (TME) with diverse immune functions that have a major in...
      Speaker: Thibaut Janss, PhD
      Sponsored By: Miltenyi Biotec
      6 1
      OCT 15, 2020 | 9:00 AM
      Evaluating the Kidney-Chip for Transporter-Mediated Drug-Drug Interactions Applications
      Evaluating the Kidney-Chip for Transporter-Mediated Drug-Drug...
      Date: October 15, 2020 Time: 9:00am (PDT), 12:00pm (EDT) Renal transporters play an important role in potential clinical drug-drug interactions (DDIs) as highlighted in the FDA, EMA and PMDA...
      Speaker: Steven Anderson, PhD , Kyung-Jin Jang, PhD , Donald McKenzie, PhD
      Sponsored By: Emulate
      9
      OCT 08, 2020 | 6:00 PM
      Multimodal analysis of circulating cell-free RNA (ccfRNA), cell-free DNA (ccfDNA), genomic DNA (gDNA) and CTCs from blood samples in cancer research
      Multimodal analysis of circulating cell-free RNA (ccfRNA), cell-free...
      While circulating cell-free DNA (ccfDNA) and to some extend CTCs from blood are routinely used as analyte in liquid biopsy cancer research applications, circulating cell-free RNA (ccfRNA) ha...
      Speaker: Thorsten Voss, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
      Sponsored By: QIAGEN
      4
      OCT 08, 2020 | 6:00 PM
      High-throughput biomarker profiling in immuno-oncology research & development
      High-throughput biomarker profiling in immuno-oncology research...
      Soluble cytokine biomarkers are the master regulators of cell-to-cell communication-- the means by which one cell tells another what to do or where to go. Determining the biomarker signature...
      Speaker: Jenny Koenitzer, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
      Sponsored By: MilliporeSigma
      3
      OCT 08, 2020 | 4:30 PM
      Multiplex detection of oncogenic mutations using LNA-based assays on the QIAcuity digital PCR system
      Multiplex detection of oncogenic mutations using LNA-based assays...
      Multiplex detection of oncogenic mutations using LNA-based assays on the QIAcuity digital PCR system Digital PCR (dPCR) enables specific and sensitive detection of genetic alterations in onc...
      Speaker: Dr. Özlem Karalay
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
      Sponsored By: QIAGEN
      2
      OCT 08, 2020 | 3:00 PM
      Reducing biological variance in tumor-antigen expression to standardize potency testing for immunotherapies
      Reducing biological variance in tumor-antigen expression to standardize...
      The continued rapid expansion of immunotherapies, including both in vivo and ex vivo therapeutics, has driven the development and adoption of novel tools to study, asses and understand these...
      Speaker: Benjamin Borgo, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
      Sponsored By: MilliporeSigma
      1
    NOV 12, 2020 | 1:30 PM
    Covid-19 Testing and the role of Antigen assays today and moving forward
    Covid-19 Testing and the role of Antigen assays today and moving...
    Today's presentation will cover the following topics from the perspective of a NYC based Laboratory: What have we learned year to date about CoV-2 and specifically how diagnostic testing...
    Speaker: Vincent Streva, PhD
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2020
    Sponsored By: Diasorin
    1
    November 12, 2020 11:00 AM PST | 6:00 PM GMT
    Q&A Session (In the RoundTable Room)
    Q&A Session (In the RoundTable Room)
    Visit the RoundTable Room to participate in live Q&A with all the speakers!...
    Speaker: Charalambos C. Solomides, MD , Sara Eglitis, MS, QIHC , Faruk Erdem Kombak, MD , Srabani Bhaumik, PhD , Nelson Alexander, PhD
    Presented at: DISCOVERY Global User Symposium
    1
    November 12, 2020 10:00 AM PST | 5:00 PM GMT
    Representative sampling to address tumor heterogeneity
    Representative sampling to address tumor heterogeneity
    Ensuring that clinical tests are not affected by tumor heterogeneity requires a sampling methodology that captures the genomic, proteomic, and cellular diversity of entire solid tumors. Howe...
    Speaker: Nelson Alexander, PhD
    Presented at: DISCOVERY Global User Symposium
    2
    NOV 12, 2020 | 10:00 AM
    FcRn Affinity Column Chromatography for Therapeutic mAb Characterization
    FcRn Affinity Column Chromatography for Therapeutic mAb Characterization
    Date: November 12, 2020 Time: 10:00am (PST), 1:00pm (EST) Fc receptor based affinity chromatography is a new emerging field of Fc functionality analytics. FcRn affinity columns separate anti...
    Speaker: Tilman Schlothauer, Ph.D
    Sponsored By: Roche CustomBiotech
    3
    NOV 12, 2020 | 9:00 AM
    Back to Work, School, and Life: Utility of COVID-19 Testing to Help Communities Restore Normality
    Back to Work, School, and Life: Utility of COVID-19 Testing to...
    Testing volumes need to increase by orders of magnitude in order to restore communities back to normality. This workshop focuses on solutions that equip laboratories to participate in expand...
    Speaker: Dr. Jared R. Auclair , Frank Ong, MD, CPI, CCRP
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2020
    Sponsored By: Thermo Fisher Scientific
    5
     
     
  • NOV 12, 2020 | 7:00 AM
    Cell Sorting for Multiple Applications - How to Optimize your Sort Setup
    Cell Sorting for Multiple Applications - How to Optimize your...
    Date: November 12, 2020 Time: 7:00am (PST), 10:00am (EST), 3:00pm (BST), 4:00pm (CET) Cell sorting is used for a wide range of applications, from profiling immune subsets to sorting cancer c...
    Speaker: Deena Soni, PhD , Miro Koulnis, PhD
    Sponsored By: Sony Biotechnology
    4
    NOV 12, 2020 | 12:00 AM
    Clinical utility of concussion injury biomarkers
    Clinical utility of concussion injury biomarkers
    Cases of traumatic brain injury (TBI) have been steadily rising over the past decade with most common causes of injury observed among participants in contact sports, combat military personne...
    Speaker: Paul R. Johnson, PhD, MT(ASCP), DABCC, FAACC
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2020
    1
    NOV 12, 2020 | 12:00 AM
    Principles of Effective Method Development in Pathobiology Research
    Principles of Effective Method Development in Pathobiology Research
    Immunohistochemistry (IHC) is used to determine spatial relationships where we can identify the localization of target proteins in specific regions and cells of a tissue. IHC has been the go...
    Speaker: Vivian Barry, MS
    Presented at: DISCOVERY Global User Symposium
    2
    NOV 12, 2020 | 12:00 AM
    How Artificial Intelligence can facilitate the use of cardiac biomarkers?
    How Artificial Intelligence can facilitate the use of cardiac...
    Biomarkers play a vital role in disease detection and treatment follow-up. It is important to note that the diseases in the early stage are typically treated with the greatest probability of...
    Speaker: Dr. Pradeep Kumar Dabla
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2020
    2
    NOV 05, 2020 | 7:00 AM
    Stem cell derived exosome production in stirred-tank bioreactors
    Stem cell derived exosome production in stirred-tank bioreactors
    DATE: Date needed, 2020 TIME: Time needed Exosomes are a population of naturally occurring mobile, membrane-limited, 30 – 100 nm in diameter, extracellular vesicles containing a large...
    Speaker: Jorge Escobar , Aurélie Tacheny
    Presented at: Eppendorf Planet of Knowledge - A New Dimension
    Sponsored By: Eppendorf
    12
     
     
  • OCT 29, 2020 | 6:00 AM
    Single-cell sequencing to investigate epigenetic mechanisms in inflammatory lymphocytes
    Single-cell sequencing to investigate epigenetic mechanisms in...
    Date: October 29, 2020 Time: 6:00am (PDT), 9:00am (EDT), Chronic inflammation can occur as a result of a combination of genetic predispositions and environmental factors. Epigenetic modifica...
    Speaker: Thomas Ayers, Ph.D. , Pawel Zajac, Ph.D. , Dr. Adam Cribbs
    Sponsored By: Illumina, Dolomite Bio
    15
    OCT 22, 2020 | 12:25 PM
    Clinical impact of Next-Generation Sequencing (NGS) Testing: A hematopathologist's perspective
    Clinical impact of Next-Generation Sequencing (NGS) Testing: A...
    Myeloid neoplasms represent a highly heterogeneous group of diseases that encompass myeloproliferative, myelodysplastic (myeloproliferative/myelodysplastic) processes and acute myeloid leuke...
    Speaker: Megan S. Lim, MD, PhD
    Presented at: OncomineWorld 2022: A Virtual NGS Education Meeting
    0
    OCT 22, 2020 | 12:25 PM
    Clinical impact of Next-Generation Sequencing (NGS) Testing: A hematopathologist's perspective
    Clinical impact of Next-Generation Sequencing (NGS) Testing: A...
    Myeloid neoplasms represent a highly heterogeneous group of diseases that encompass myeloproliferative, myelodysplastic (myeloproliferative/myelodysplastic) processes and acute myeloid leuke...
    Speaker: Megan S. Lim, MD, PhD
    Presented at: OncomineWorld Autumn: A virtual NGS education meeting
    2
    OCT 22, 2020 | 8:00 AM
    Driving lab efficiency with PCR power
    Driving lab efficiency with PCR power
    Abstract: Detection and/or amplification of target DNA sequences by polymerase chain reaction (PCR) is a prevalent method in molecular biology. PCR has a broad range of applications, includi...
    Speaker: Kyle Hondorp , Marija Navickaitė
    Sponsored By: Thermo Fisher Scientific
    150 2
    OCT 22, 2020 | 7:20 AM
    NGS evolution in Solid Tumours, from S5-XL to Genexus
    NGS evolution in Solid Tumours, from S5-XL to Genexus
    During the presentation, Dr. Hernandez-Losa will describe the experience in the Department of Pathology using NGS with S5-xl in different translational projects in solid tumors. Additionally...
    Speaker: Javier Hernandez-Losa, PhD
    Presented at: OncomineWorld 2022: A Virtual NGS Education Meeting
    0
     
     
  • OCT 22, 2020 | 7:20 AM
    NGS evolution in Solid Tumours, from S5-XL to Genexus
    NGS evolution in Solid Tumours, from S5-XL to Genexus
    During the presentation, Dr. Hernandez-Losa will describe the experience in the Department of Pathology using NGS with S5-xl in different translational projects in solid tumors. Additionally...
    Speaker: Javier Hernandez-Losa, PhD
    Presented at: OncomineWorld Autumn: A virtual NGS education meeting
    1
    OCT 21, 2020 | 10:35 PM
    Latest Developments with the Genexus System
    Latest Developments with the Genexus System
    The treatment of cancer has remarkably improved because of increased knowledge of the molecular abnormalities that drive human cancer growth. This has led to the development of ever more eff...
    Speaker: Dr. Jose Luis Costa
    Presented at: OncomineWorld 2022: A Virtual NGS Education Meeting
    0
    OCT 21, 2020 | 10:35 PM
    Latest Developments with the Genexus System
    Latest Developments with the Genexus System
    The treatment of cancer has remarkably improved because of increased knowledge of the molecular abnormalities that drive human cancer growth. This has led to the development of ever more eff...
    Speaker: Dr. Jose Luis Costa
    Presented at: OncomineWorld Autumn: A virtual NGS education meeting
    1
    OCT 20, 2020 | 9:00 AM
    Understanding how in vitro macrophage assays drive IO drug development forward
    Understanding how in vitro macrophage assays drive IO drug development...
    DATE: October 20th, 2020 TIME: 08:00am PT, 11:00am ET Tumor-associated macrophages (TAMs) are key cells in the tumor microenvironment (TME) with diverse immune functions that have a major in...
    Speaker: Thibaut Janss, PhD
    Sponsored By: Miltenyi Biotec
    6 1
    OCT 15, 2020 | 9:00 AM
    Evaluating the Kidney-Chip for Transporter-Mediated Drug-Drug Interactions Applications
    Evaluating the Kidney-Chip for Transporter-Mediated Drug-Drug...
    Date: October 15, 2020 Time: 9:00am (PDT), 12:00pm (EDT) Renal transporters play an important role in potential clinical drug-drug interactions (DDIs) as highlighted in the FDA, EMA and PMDA...
    Speaker: Steven Anderson, PhD , Kyung-Jin Jang, PhD , Donald McKenzie, PhD
    Sponsored By: Emulate
    9
     
     
  • OCT 08, 2020 | 6:00 PM
    Multimodal analysis of circulating cell-free RNA (ccfRNA), cell-free DNA (ccfDNA), genomic DNA (gDNA) and CTCs from blood samples in cancer research
    Multimodal analysis of circulating cell-free RNA (ccfRNA), cell-free...
    While circulating cell-free DNA (ccfDNA) and to some extend CTCs from blood are routinely used as analyte in liquid biopsy cancer research applications, circulating cell-free RNA (ccfRNA) ha...
    Speaker: Thorsten Voss, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
    Sponsored By: QIAGEN
    4
    OCT 08, 2020 | 6:00 PM
    High-throughput biomarker profiling in immuno-oncology research & development
    High-throughput biomarker profiling in immuno-oncology research...
    Soluble cytokine biomarkers are the master regulators of cell-to-cell communication-- the means by which one cell tells another what to do or where to go. Determining the biomarker signature...
    Speaker: Jenny Koenitzer, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
    Sponsored By: MilliporeSigma
    3
    OCT 08, 2020 | 4:30 PM
    Multiplex detection of oncogenic mutations using LNA-based assays on the QIAcuity digital PCR system
    Multiplex detection of oncogenic mutations using LNA-based assays...
    Multiplex detection of oncogenic mutations using LNA-based assays on the QIAcuity digital PCR system Digital PCR (dPCR) enables specific and sensitive detection of genetic alterations in onc...
    Speaker: Dr. Özlem Karalay
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
    Sponsored By: QIAGEN
    2
    OCT 08, 2020 | 3:00 PM
    Reducing biological variance in tumor-antigen expression to standardize potency testing for immunotherapies
    Reducing biological variance in tumor-antigen expression to standardize...
    The continued rapid expansion of immunotherapies, including both in vivo and ex vivo therapeutics, has driven the development and adoption of novel tools to study, asses and understand these...
    Speaker: Benjamin Borgo, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
    Sponsored By: MilliporeSigma
    1
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