Cell Line Development
Cell Line Development: Stable cell lines are widely used in a number of important applications including biologics (e.g. recombinant protein and monoclonal antibody) production, drug screening, and gene functional studies. The process of developing stable cell lines often starts with transfecting selected host cells, typically CHO or HEK 293 cells, with desired plasmids. After transfection, researchers then screen and quantify high-expressing clones. Once these high producers are identified, the cell lines and/or the proteins produced by the cells are validated. The manual screening methods traditionally used for cell line development are time-consuming and labor-intensive, creating a great demand for high-throughput, automated solutions for such efforts.
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APR 17, 2019
Cannabis Sciences
APR 17, 2019
According to Barrons, an online and print news outlet, marijuana is getting a second look by clinicians, pharmaceuticals, and consumers. In a piece wr...
Written By:
Amy Loriaux
MAR 01, 2019
Cancer
MAR 01, 2019
Cell division is one of the most fundamental processes in biology. In eukaryotes, there are several phases of the cycle, during which DNA is replicated and...
Written By:
Carmen Leitch
DEC 27, 2018
Videos
DEC 27, 2018
The CDC found that at least a dozen people were sickened last year by unapproved stem cell treatments....
Written By:
Carmen Leitch
DEC 14, 2018
Cancer
DEC 14, 2018
Chimeric antigen receptor T cells (CAR-T cells) have emerged as a useful tool for cancer treatments in a small number of cancers thus far. This area of treatment research is expanding rapidl...
Written By:
Mauri Brueggeman
DEC 09, 2018
Videos
DEC 09, 2018
Researchers are growing mini-retinas to learn more about color vision, and why it's dysfunctional in some people....
Written By:
Carmen Leitch
NOV 25, 2018
Microbiology
NOV 25, 2018
First identified in 1993, hantavirus infections can cause dangerous and potentially deadly respiratory infections....
Written By:
Carmen Leitch
NOV 07, 2018
Genetics & Genomics
NOV 07, 2018
Researchers want to identify the tiny, non-coding RNAs that control gene expression - and contribute to disease....
Written By:
Carmen Leitch
OCT 07, 2018
Cell & Molecular Biology
OCT 07, 2018
If we learn how the heart is built, we may learn how to mend a broken one....
Written By:
Carmen Leitch
OCT 06, 2018
Drug Discovery
OCT 06, 2018
Scientists at Stevens Institute of Technology have designed a new class of molecules that may hold the potential to add to the arsenal of drugs actively be...
Written By:
Nouran Amin
OCT 04, 2018
Videos
OCT 04, 2018
Cannabis is known to treat nausea and vomiting from cancer chemotherapy. Most recent studies have revealed that THC and other cannabinoids are able to slow...
Written By:
Amanda Kahl
OCT 04, 2018
Genetics & Genomics
OCT 04, 2018
Neuroscience
OCT 04, 2018
A due date for a baby represents great hope to parents and families. Any due date is an educated guess, and some babies arrive a little early or a little l...
Written By:
Brenda Kelley Kim
OCT 03, 2018
Immunology
OCT 03, 2018
A team of researchers from Duke Human Vaccine Institute has recently published their work regarding the interplay of natural killer cells (NK cells) and broadly neutralizing antibodies (bnAbs...
Written By:
Nicholas Breehl
OCT 02, 2018
Drug Discovery
OCT 02, 2018
New drug seeking to treat antibiotic-resistant lung disease has just been approved by the U.S. Food and Drug Administration. The drug is called ‘Arik...
Written By:
Nouran Amin
OCT 01, 2018
Immunology
OCT 01, 2018
The immune system consists of a variety of different cell types. But how do the cells undergo differentiation? A study recently published in Science provides insight....
Written By:
Nicholas Breehl
SEP 28, 2018
Genetics & Genomics
SEP 28, 2018
Over fifty years ago, scientists in Russia began to selectively breed silver foxes to replicate domestication....
Written By:
Carmen Leitch
SEP 27, 2018
Genetics & Genomics
SEP 27, 2018
According to the EPA, algal blooms threaten every state and in our changing climate, they may be more common....
Written By:
Carmen Leitch
SEP 25, 2018
Cell & Molecular Biology
SEP 25, 2018
Researchers at Caltech have taken an interesting approach to synthetic biology....
Written By:
Carmen Leitch
SEP 25, 2018
Health & Medicine
SEP 25, 2018
While many parents are cautious about the cleaning products they use around the house because small children could ingest them and become ill, most parents...
Written By:
Brenda Kelley Kim
SEP 24, 2018
Drug Discovery
SEP 24, 2018
A paper published in journal Molecular Cell, describes a naturally occurring antibiotic known as kanglemycin A which is related to the antibiotic rifampici...
Written By:
Nouran Amin
SEP 24, 2018
Genetics & Genomics
SEP 24, 2018
Driving is an everyday activity for many people around the world, and it comes with serious risks....
Written By:
Carmen Leitch
SEP 18, 2018
Drug Discovery
SEP 18, 2018
Fighting disease using the immune system is the body’s most prized possession and it does so by utilizing immunotherapy. However, a discovery by rese...
Written By:
Nouran Amin
SEP 17, 2018
Cell & Molecular Biology
SEP 17, 2018
Scientists have developed a better way to create astrocytes, a cell type hat has been implicated in neurodegenerative diseases....
Written By:
Carmen Leitch
SEP 17, 2018
Microbiology
SEP 17, 2018
Evidence mounts that viruses play a role in disease development....
Written By:
Carmen Leitch
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