Cell Line Development
Cell Line Development: Stable cell lines are widely used in a number of important applications including biologics (e.g. recombinant protein and monoclonal antibody) production, drug screening, and gene functional studies. The process of developing stable cell lines often starts with transfecting selected host cells, typically CHO or HEK 293 cells, with desired plasmids. After transfection, researchers then screen and quantify high-expressing clones. Once these high producers are identified, the cell lines and/or the proteins produced by the cells are validated. The manual screening methods traditionally used for cell line development are time-consuming and labor-intensive, creating a great demand for high-throughput, automated solutions for such efforts.
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JUN 22, 2022
Cell & Molecular Biology
JUN 22, 2022
Introduction Centrifugation and filtration have been widely accepted as techniques required for clarifying complex cell
...
Sponsored By:
Pall Corporation
JUN 20, 2022
Cancer
JUN 20, 2022
Uterine cancer develops when cells in the inner lining of the uterus, known as the endometrium, undergo uncontrolled and
...
Written By:
Katie Kokolus
JUN 11, 2022
Drug Discovery & Development
JUN 11, 2022
Inhaled aerosol vaccines provide more protection than nasal sprays and evoke a stronger immune response. The correspondi
...
Written By:
Annie Lennon
JUN 09, 2022
Technology
JUN 09, 2022
All living organisms are made of cells, as cells are the basic units of life. Cells are magnificent little things and th
...
Written By:
Laurence Tognetti, MSc
JUN 06, 2022
Immunology
JUN 06, 2022
Cancer can arise from a variety of aberrations that cause cells to divide uncontrollably, and form a tumor. The causes o
...
Written By:
Carmen Leitch
MAY 25, 2022
Cell & Molecular Biology
MAY 25, 2022
Gene editing has Brough beneficial changes to many foods. Now, researchers have engineered a plant that produced tomatoe
...
Written By:
Carmen Leitch
MAY 19, 2022
Cancer
MAY 19, 2022
Recurrent cancer develops when undetectable cancer cells remain in the body following treatment. Cancer recurrence
...
Written By:
Katie Kokolus
APR 28, 2022
Drug Discovery & Development
APR 28, 2022
A molecule produced when on low-carbohydrate ketogenic diets suppresses the growth of colorectal tumors in the lab. The
...
Written By:
Annie Lennon
APR 25, 2022
Cancer
APR 25, 2022
Substantial evidence supports the association between exercise and reduced risk of colon cancer. Physical act
...
Written By:
Katie Kokolus
APR 21, 2022
Immunology
APR 21, 2022
Innate lymphoid cells (ILCs) are part of the innate immune system, a generalized response to pathogens. These cells are
...
Written By:
Carmen Leitch
APR 20, 2022
Immunology
APR 20, 2022
Antibiotic resistance has increased the demand for new antibiotic treatments. Now, researchers have found that a
...
Written By:
Annie Lennon
APR 15, 2022
Immunology
APR 15, 2022
The immune system is an incredibly complex system that has to be able to rapidly spring into action, and then shut down
...
Written By:
Carmen Leitch
APR 14, 2022
Drug Discovery & Development
APR 14, 2022
COVID-19 is more effectively treated by a combination of drugs than singular drugs alone. The corresponding study was pu
...
Written By:
Annie Lennon
APR 08, 2022
Immunology
APR 08, 2022
Zinc is a mineral that's known to boost the function of the immune system, and now scientists have learned more about ho
...
Written By:
Carmen Leitch
MAR 11, 2022
Immunology
MAR 11, 2022
T cells are on the front lines of the immune system, and many reside in the blood and lymph nodes, surveying for and res
...
Written By:
Carmen Leitch
MAR 07, 2022
Immunology
MAR 07, 2022
T cells are on the front lines of the immune system, and can work against infections and cancer cells. But the activity
...
Written By:
Carmen Leitch
FEB 17, 2022
Technology
FEB 17, 2022
The use of synthetic models replicating parts of the human body (often called “organoids”), has emerged in r
...
Written By:
Ryan Vingum
FEB 11, 2022
Cannabis Sciences
FEB 11, 2022
According to a recent study published in Oncotarget, cannabis extracts may harbor the potential to eventually be tailore
...
Written By:
Nadine Husami
FEB 04, 2022
Cell & Molecular Biology
FEB 04, 2022
Germ cells are not like most other cell types, because they are able to undergo meiosis to produce gametes as well as mi
...
Written By:
Carmen Leitch
FEB 03, 2022
Immunology
FEB 03, 2022
Researchers have created nanoparticles that mimic the effects of blood platelets to stop heavy bleeding. Biomedic
...
Written By:
Tara Fernandes
JAN 27, 2022
Immunology
JAN 27, 2022
Plastics are devastating the environment, and a growing body of research is pointing to how they can also negatively imp
...
Written By:
Tara Fernandes
JAN 18, 2022
Clinical & Molecular DX
JAN 18, 2022
Besides being a mood booster, spending time in the sun is known to have a number of health benefits. For example,
...
Written By:
Tara Fernandes
JAN 10, 2022
Cancer
JAN 10, 2022
Racial disparities exist between Black and White populations in many types of cancer. Researchers actively investi
...
Written By:
Katie Kokolus
JAN 07, 2022
Cancer
JAN 07, 2022
The blood-brain barrier (BBB) describes the complex vasculature network that delivers oxygen and nutrients to the brain.
...
Written By:
Katie Kokolus
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