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    Cell Line Development

    Cell Line Development: Stable cell lines are widely used in a number of important applications including biologics (e.g. recombinant protein and monoclonal antibody) production, drug screening, and gene functional studies. The process of developing stable cell lines often starts with transfecting selected host cells, typically CHO or HEK 293 cells, with desired plasmids. After transfection, researchers then screen and quantify high-expressing clones. Once these high producers are identified, the cell lines and/or the proteins produced by the cells are validated. The manual screening methods traditionally used for cell line development are time-consuming and labor-intensive, creating a great demand for high-throughput, automated solutions for such efforts.

    Webinars

    • NOV 20, 2025 | 8:00 AM
      High-Throughput Clone Screening Under Manufacturing-Relevant Conditions with the Cydem VT System
      High-Throughput Clone Screening Under Manufacturing-Relevant Conditions...
      Cell line development (CLD) is often a critical bottleneck in biopharmaceutical production, often requiring labor-intensive workflows and multiple sequential screening steps that extend time...
      Speaker: Abigail Lee
      Sponsored By: Beckman Coulter Life Sciences
      4
      FEB 12, 2025 | 8:00 AM
      Clonality is King: Advancing Cell Line Development with Automated Single Cell Dispensing
      Clonality is King: Advancing Cell Line Development with Automated...
      Single cell isolation is a necessary step for a variety of applications from developing productive, stable cell lines for biologics manufacturing to developing CRISPR edited iPSCs for diseas...
      Speaker: Ryan McComb, Ph.D.
      Presented at: The Simple Way to Protein Research
      2
      JUN 04, 2024 | 11:00 AM
      Development of an on-chip binding assay to select clones expressing bispecific antibodies
      Development of an on-chip binding assay to select clones expressing...
      TBD...
      Speaker: Shu Wang, Ph.D.
      Presented at: Antibody and Cell Therapy Development: The Life of Single Cells on Beacon® Platform
      2
      JUN 04, 2024 | 8:15 AM
      Harnessing the Power of Beacon Platform to Accelerate Antibody Discovery and Cell Therapy Development
      Harnessing the Power of Beacon Platform to Accelerate Antibody...
      The revolution in life science research aims to understand how single cells work, which is crucial for developing new therapies. Traditional methods like FACS and scRNASeq give only a partia...
      Speaker: Vikram Devgan, PhD
      Presented at: Antibody and Cell Therapy Development: The Life of Single Cells on Beacon® Platform
      2
      APR 03, 2024 | 9:00 AM
      C.E. CREDITS
      Keynote Presentation: Mammalian Cell Systems for Production of Therapeutic Proteins and Carbohydrates- Advances in Cell Line Development and Bioprocessing with Live Q&A
      Keynote Presentation: Mammalian Cell Systems for Production of...
      Cultured mammalian cells, particularly Chinese hamster ovary (CHO) cells are widely used in the biotechnology industry for production of a wide range of therapeutics, predominantly monoclona...
      Speaker: Susan Sharfstein
      Presented at: Bioprocessing Virtual Event Series 2024
      3
      MAR 20, 2024 | 8:00 AM
      Introducing the first dual reporter application for Luminex xMAP INTELLIFLEX DR-SE Instruments:  measurement of phosphorylated and total proteins on the same bead
      Introducing the first dual reporter application for Luminex xMAP...
      Luminex and Thermo Fisher Scientific are excited to feature two presentations highlighting the advanced features of the Invitrogen™ Luminex® xMAP® INTELLIFLEX™ DR-SE inst...
      Speaker: Sherry Dunbar, Ph.D., MBA , Sigrun Badrnya, Ph.D.
      Sponsored By: Thermo Fisher Scientific
      11
      MAR 20, 2024 | 7:30 AM
      Panel Presentation: Advanced Predictive Modeling in Cell Line Development with Live Q&A
      Panel Presentation: Advanced Predictive Modeling in Cell Line...
      Biopharmaceutical manufacturing of proteins requires an efficient cell line. Starting with several thousand clones, researchers use multiple selection rounds to ultimately chose one clone fo...
      Speaker: Ali Safari, Dr.-Ing , Monika Zauner, Dr
      Presented at: Laboratory Automation Virtual Event Series 2024
      Sponsored By: Sartorius
      4
      JAN 23, 2024 | 12:00 PM
      Retaining Cell Viability and Morphology in IPSCs: Vital Tools for Research
      Retaining Cell Viability and Morphology in IPSCs: Vital Tools...
      From drug discovery to organoid modeling of disease, stem cells are increasingly being used in research as a vital tool for scientific investigation. Due to the specialized nature of stem ce...
      Speaker: Daryl Cole
      Presented at: The Future of Biomedicine: Reproducible Advanced Cell Systems and Translational Insights
      3
      DEC 12, 2023 | 8:00 PM
      Gibco Cell Culture Hero Webinar: From Development to Regeneration: The Role of Epicardium
      Gibco Cell Culture Hero Webinar: From Development to Regeneration:...
      Embryonic epicardium is crucial for normal heart morphogenesis. The tissue originates from the proepicardial organ, with cells migrating to form the outer mesothelial layer, giving rise to n...
      Speaker: Dr. Jun Jie (JJ) Tan
      Sponsored By: Thermo Fisher Scientific
      16
      NOV 29, 2023 | 9:00 AM
      Labcorp® Plasma Focus™
      Labcorp® Plasma Focus™
      Tumor genomic profiling can be complicated, especially for diseases that commonly have multiple different genomic biomarkers of interest, such as non-small cell lung cancer (NSCLC) and color...
      Speaker: Mark Sausen, PhD , Mohamad Khasawneh, MD
      Sponsored By: Labcorp Oncology
      21
      NOV 01, 2023 | 8:00 AM
      Accelerating Cell Therapy Clinical Trials With Comprehensive Biomarker-Driven Strategies
      Accelerating Cell Therapy Clinical Trials With Comprehensive Biomarker-Driven...
      To bring your cutting-edge cell and gene therapies to the patients that need them as quickly as possible, you need access to the most knowledgeable scientists, innovative technologies, metho...
      Speaker: NingChun Liu, PhD , Yoav Peretz, PhD , Vijay Ramakrishnan, PhD , Matthew Evans, PhD , Sarabjot (Sabi) Pabla, PhD
      Sponsored By: Labcorp
      11
      OCT 25, 2023 | 10:00 AM
      Introduction of a New Thiol-based Fluorescent Indicator to Assess Cellular Health Using Induced Pluripotent Stem Cell Derived Neurons
      Introduction of a New Thiol-based Fluorescent Indicator to Assess...
      Oxidative stress, a critical factor affecting cell health, has gained prominence in assessing various medical conditions. Given this importance, researchers need a wide range of tools to tho...
      Speaker: Daniel Sem, Ph.D., MBA, JD , Roxanne Alvarez, Ph.D.
      Sponsored By: BrainXell, Vivid Microscopy
      10
      OCT 24, 2023 | 8:00 AM
      Scaling Up Organoid Research: A New Approach with Assay-Ready Organoids
      Scaling Up Organoid Research: A New Approach with Assay-Ready...
      Organoids are three-dimensional (3D) multi-cellular, microtissues derived from stem cells that closely mimic the complex structure and functionality of human organs. They offer more accurate...
      Speaker: Angeline Lim , Andy Bashford
      Sponsored By: Molecular Devices
      9
      OCT 24, 2023 | 8:00 AM
      Key Considerations for Driving Gene Therapy Programs Successfully Through IND/CTA and Beyond
      Key Considerations for Driving Gene Therapy Programs Successfully...
      To bring your cutting-edge cell and gene therapies to the patients that need them as quickly as possible, you need access to the most knowledgeable scientists, innovative technologies, metho...
      Speaker: Brian McIntosh, PhD , Tracy Iles, BSc , Jay Herman, PhD , Peter Sonnentag, MS , Colin Guy, PhD
      Sponsored By: Labcorp
      18
      OCT 24, 2023 | 10:00 AM
      Scaling Up Organoid Research: A New Approach with Assay-Ready Organoids
      Scaling Up Organoid Research: A New Approach with Assay-Ready...
      Organoids are three-dimensional (3D) multi-cellular, microtissues derived from stem cells that closely mimic the complex structure and functionality of human organs. They offer more accurate...
      Speaker: Angeline Lim , Andy Bashford
      Sponsored By: Molecular Devices
      12
      OCT 04, 2023 | 6:00 AM
      Unlocking the Potential of Cancer Therapeutic Antibodies: GenScript's Immune Checkpoint and Therapeutic Antibody Solutions with Live Q&A
      Unlocking the Potential of Cancer Therapeutic Antibodies: GenScript's...
      In the ever-evolving landscape of cancer therapy, immune checkpoint inhibitors have emerged as promising avenues for therapeutic antibody development. Our presentation will share GenScript&#...
      Speaker: Amanda Grimm, B.S., PSM
      Presented at: Cancer Research & Immuno-Oncology Week Virtual Event Series 2023
      Sponsored By: GenScript
      1
      SEP 12, 2023 | 10:00 AM
      CHOp your protein production timelines
      CHOp your protein production timelines
      Register to learn more about how to rapidly and reproducibly drive your developmental efforts forward by leveraging MaxCyte’s flow electroporation technology. Labs adopt this scalable...
      Speaker: James Brady, PhD , Caroline Romanelli , Megan Embrey
      Sponsored By: MaxCyte®
      17
      AUG 10, 2023 | 8:00 AM
      Current Landscape and Future Directions of Multi-specific Antibodies
      Current Landscape and Future Directions of Multi-specific Antibodies
      Antibody therapeutics is a fast-growing market boosted by developments in bispecific antibodies and in newly emerging tetra-specific antibodies. With the ability to recruit a combination of...
      Speaker: Shebna Massey, PhD
      Sponsored By: Sino Biological
      14
      JUL 26, 2023 | 12:55 PM
      Developing genetic engineering tools for non-conventional and non-model yeast
      Developing genetic engineering tools for non-conventional and...
      Microorganisms have always been integral to natural circular processes in the environment. They serve an important role in converting complex biological molecules into central building block...
      Speaker: Dr. Mark Blenner
      Presented at: GenScript 3rd Annual Gene and Cell Engineering Summit
      4
      JUL 26, 2023 | 12:15 PM
      Advancing Protein Stabilization Therapeutic Development and DUBTAC Drug Discovery through Gene and Cell Engineering
      Advancing Protein Stabilization Therapeutic Development and DUBTAC...
      Genetically modified cell models accelerate the development of safe and effective therapeutics, making them indispensable in the quest for new drugs. Through manipulation of cell line geneti...
      Speaker: Dr. Yongli Shan
      Presented at: GenScript 3rd Annual Gene and Cell Engineering Summit
      4
      JUL 18, 2023 2:00 PM EDT
      Biomarkers in Gastric Cancer: An Overview
      Biomarkers in Gastric Cancer: An Overview
      Worldwide gastric cancer is the 5th most common cancer and the 4th leading cause of cancer deaths. Its highest incidence rates are in east Asia and eastern Europe with low incidence rates in...
      Speaker: Stuti Shroff, MD, MBBS, PhD
      Presented at: Precision Medicine in Solid Tumors
      11
      APR 25, 2023 | 10:00 AM
      Enumeration and Molecular Profiling of Circulating Tumor Cells for Diagnosis and Therapeutic Monitoring of Metastatic Cancer
      Enumeration and Molecular Profiling of Circulating Tumor Cells...
      Date: April 25, 2023 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) A liquid biopsy is a non-invasive alternative to a surgical biopsy that enables researchers to learn a range of infor...
      Speaker: Pravin Potdar
      Sponsored By: Thermo Fisher Scientific
      20 1
      APR 05, 2023 | 9:30 AM
      Optimizing Clone Selection in Cell Line Development with Live Q&A
      Optimizing Clone Selection in Cell Line Development with Live...
      From gene cloning and initial clone selection through to final cell evaluation, the continual assessment of cell count and viability is important for determining the best growing and highest...
      Speaker: Daryl Cole, PhD
      Presented at: Bioprocessing Virtual Event Series 2023
      Sponsored By: Sartorius
      3
      MAR 30, 2023 | 5:00 PM
      Memory-rich CAR-T cell engineering by piggyBac transposon system for solid malignancies
      Memory-rich CAR-T cell engineering by piggyBac transposon system...
      Date: March 30, 2023 Time: 5:00pm (PST), 8:00pm (EST) March 31, 2023 9:00am (JST) Chimeric antigen receptor T cell (CAR-T) therapy is still challenging in targeting solid malignancies. The q...
      Speaker: Dr. Shigeki Yagyu
      Sponsored By: MaxCyte®
      15
    NOV 20, 2025 | 8:00 AM
    High-Throughput Clone Screening Under Manufacturing-Relevant Conditions with the Cydem VT System
    High-Throughput Clone Screening Under Manufacturing-Relevant Conditions...
    Cell line development (CLD) is often a critical bottleneck in biopharmaceutical production, often requiring labor-intensive workflows and multiple sequential screening steps that extend time...
    Speaker: Abigail Lee
    Sponsored By: Beckman Coulter Life Sciences
    4
    FEB 12, 2025 | 8:00 AM
    Clonality is King: Advancing Cell Line Development with Automated Single Cell Dispensing
    Clonality is King: Advancing Cell Line Development with Automated...
    Single cell isolation is a necessary step for a variety of applications from developing productive, stable cell lines for biologics manufacturing to developing CRISPR edited iPSCs for diseas...
    Speaker: Ryan McComb, Ph.D.
    Presented at: The Simple Way to Protein Research
    2
    JUN 04, 2024 | 11:00 AM
    Development of an on-chip binding assay to select clones expressing bispecific antibodies
    Development of an on-chip binding assay to select clones expressing...
    TBD...
    Speaker: Shu Wang, Ph.D.
    Presented at: Antibody and Cell Therapy Development: The Life of Single Cells on Beacon® Platform
    2
    JUN 04, 2024 | 8:15 AM
    Harnessing the Power of Beacon Platform to Accelerate Antibody Discovery and Cell Therapy Development
    Harnessing the Power of Beacon Platform to Accelerate Antibody...
    The revolution in life science research aims to understand how single cells work, which is crucial for developing new therapies. Traditional methods like FACS and scRNASeq give only a partia...
    Speaker: Vikram Devgan, PhD
    Presented at: Antibody and Cell Therapy Development: The Life of Single Cells on Beacon® Platform
    2
    APR 03, 2024 | 9:00 AM
    C.E. CREDITS
    Keynote Presentation: Mammalian Cell Systems for Production of Therapeutic Proteins and Carbohydrates- Advances in Cell Line Development and Bioprocessing with Live Q&A
    Keynote Presentation: Mammalian Cell Systems for Production of...
    Cultured mammalian cells, particularly Chinese hamster ovary (CHO) cells are widely used in the biotechnology industry for production of a wide range of therapeutics, predominantly monoclona...
    Speaker: Susan Sharfstein
    Presented at: Bioprocessing Virtual Event Series 2024
    3
     
     
  • MAR 20, 2024 | 8:00 AM
    Introducing the first dual reporter application for Luminex xMAP INTELLIFLEX DR-SE Instruments:  measurement of phosphorylated and total proteins on the same bead
    Introducing the first dual reporter application for Luminex xMAP...
    Luminex and Thermo Fisher Scientific are excited to feature two presentations highlighting the advanced features of the Invitrogen™ Luminex® xMAP® INTELLIFLEX™ DR-SE inst...
    Speaker: Sherry Dunbar, Ph.D., MBA , Sigrun Badrnya, Ph.D.
    Sponsored By: Thermo Fisher Scientific
    11
    MAR 20, 2024 | 7:30 AM
    Panel Presentation: Advanced Predictive Modeling in Cell Line Development with Live Q&A
    Panel Presentation: Advanced Predictive Modeling in Cell Line...
    Biopharmaceutical manufacturing of proteins requires an efficient cell line. Starting with several thousand clones, researchers use multiple selection rounds to ultimately chose one clone fo...
    Speaker: Ali Safari, Dr.-Ing , Monika Zauner, Dr
    Presented at: Laboratory Automation Virtual Event Series 2024
    Sponsored By: Sartorius
    4
    JAN 23, 2024 | 12:00 PM
    Retaining Cell Viability and Morphology in IPSCs: Vital Tools for Research
    Retaining Cell Viability and Morphology in IPSCs: Vital Tools...
    From drug discovery to organoid modeling of disease, stem cells are increasingly being used in research as a vital tool for scientific investigation. Due to the specialized nature of stem ce...
    Speaker: Daryl Cole
    Presented at: The Future of Biomedicine: Reproducible Advanced Cell Systems and Translational Insights
    3
    DEC 12, 2023 | 8:00 PM
    Gibco Cell Culture Hero Webinar: From Development to Regeneration: The Role of Epicardium
    Gibco Cell Culture Hero Webinar: From Development to Regeneration:...
    Embryonic epicardium is crucial for normal heart morphogenesis. The tissue originates from the proepicardial organ, with cells migrating to form the outer mesothelial layer, giving rise to n...
    Speaker: Dr. Jun Jie (JJ) Tan
    Sponsored By: Thermo Fisher Scientific
    16
    NOV 29, 2023 | 9:00 AM
    Labcorp® Plasma Focus™
    Labcorp® Plasma Focus™
    Tumor genomic profiling can be complicated, especially for diseases that commonly have multiple different genomic biomarkers of interest, such as non-small cell lung cancer (NSCLC) and color...
    Speaker: Mark Sausen, PhD , Mohamad Khasawneh, MD
    Sponsored By: Labcorp Oncology
    21
     
     
  • NOV 01, 2023 | 8:00 AM
    Accelerating Cell Therapy Clinical Trials With Comprehensive Biomarker-Driven Strategies
    Accelerating Cell Therapy Clinical Trials With Comprehensive Biomarker-Driven...
    To bring your cutting-edge cell and gene therapies to the patients that need them as quickly as possible, you need access to the most knowledgeable scientists, innovative technologies, metho...
    Speaker: NingChun Liu, PhD , Yoav Peretz, PhD , Vijay Ramakrishnan, PhD , Matthew Evans, PhD , Sarabjot (Sabi) Pabla, PhD
    Sponsored By: Labcorp
    11
    OCT 25, 2023 | 10:00 AM
    Introduction of a New Thiol-based Fluorescent Indicator to Assess Cellular Health Using Induced Pluripotent Stem Cell Derived Neurons
    Introduction of a New Thiol-based Fluorescent Indicator to Assess...
    Oxidative stress, a critical factor affecting cell health, has gained prominence in assessing various medical conditions. Given this importance, researchers need a wide range of tools to tho...
    Speaker: Daniel Sem, Ph.D., MBA, JD , Roxanne Alvarez, Ph.D.
    Sponsored By: BrainXell, Vivid Microscopy
    10
    OCT 24, 2023 | 8:00 AM
    Scaling Up Organoid Research: A New Approach with Assay-Ready Organoids
    Scaling Up Organoid Research: A New Approach with Assay-Ready...
    Organoids are three-dimensional (3D) multi-cellular, microtissues derived from stem cells that closely mimic the complex structure and functionality of human organs. They offer more accurate...
    Speaker: Angeline Lim , Andy Bashford
    Sponsored By: Molecular Devices
    9
    OCT 24, 2023 | 8:00 AM
    Key Considerations for Driving Gene Therapy Programs Successfully Through IND/CTA and Beyond
    Key Considerations for Driving Gene Therapy Programs Successfully...
    To bring your cutting-edge cell and gene therapies to the patients that need them as quickly as possible, you need access to the most knowledgeable scientists, innovative technologies, metho...
    Speaker: Brian McIntosh, PhD , Tracy Iles, BSc , Jay Herman, PhD , Peter Sonnentag, MS , Colin Guy, PhD
    Sponsored By: Labcorp
    18
    OCT 24, 2023 | 10:00 AM
    Scaling Up Organoid Research: A New Approach with Assay-Ready Organoids
    Scaling Up Organoid Research: A New Approach with Assay-Ready...
    Organoids are three-dimensional (3D) multi-cellular, microtissues derived from stem cells that closely mimic the complex structure and functionality of human organs. They offer more accurate...
    Speaker: Angeline Lim , Andy Bashford
    Sponsored By: Molecular Devices
    12
     
     
  • OCT 04, 2023 | 6:00 AM
    Unlocking the Potential of Cancer Therapeutic Antibodies: GenScript's Immune Checkpoint and Therapeutic Antibody Solutions with Live Q&A
    Unlocking the Potential of Cancer Therapeutic Antibodies: GenScript's...
    In the ever-evolving landscape of cancer therapy, immune checkpoint inhibitors have emerged as promising avenues for therapeutic antibody development. Our presentation will share GenScript&#...
    Speaker: Amanda Grimm, B.S., PSM
    Presented at: Cancer Research & Immuno-Oncology Week Virtual Event Series 2023
    Sponsored By: GenScript
    1
    SEP 12, 2023 | 10:00 AM
    CHOp your protein production timelines
    CHOp your protein production timelines
    Register to learn more about how to rapidly and reproducibly drive your developmental efforts forward by leveraging MaxCyte’s flow electroporation technology. Labs adopt this scalable...
    Speaker: James Brady, PhD , Caroline Romanelli , Megan Embrey
    Sponsored By: MaxCyte®
    17
    AUG 10, 2023 | 8:00 AM
    Current Landscape and Future Directions of Multi-specific Antibodies
    Current Landscape and Future Directions of Multi-specific Antibodies
    Antibody therapeutics is a fast-growing market boosted by developments in bispecific antibodies and in newly emerging tetra-specific antibodies. With the ability to recruit a combination of...
    Speaker: Shebna Massey, PhD
    Sponsored By: Sino Biological
    14
    JUL 26, 2023 | 12:55 PM
    Developing genetic engineering tools for non-conventional and non-model yeast
    Developing genetic engineering tools for non-conventional and...
    Microorganisms have always been integral to natural circular processes in the environment. They serve an important role in converting complex biological molecules into central building block...
    Speaker: Dr. Mark Blenner
    Presented at: GenScript 3rd Annual Gene and Cell Engineering Summit
    4
    JUL 26, 2023 | 12:15 PM
    Advancing Protein Stabilization Therapeutic Development and DUBTAC Drug Discovery through Gene and Cell Engineering
    Advancing Protein Stabilization Therapeutic Development and DUBTAC...
    Genetically modified cell models accelerate the development of safe and effective therapeutics, making them indispensable in the quest for new drugs. Through manipulation of cell line geneti...
    Speaker: Dr. Yongli Shan
    Presented at: GenScript 3rd Annual Gene and Cell Engineering Summit
    4
     
     
  • JUL 18, 2023 2:00 PM EDT
    Biomarkers in Gastric Cancer: An Overview
    Biomarkers in Gastric Cancer: An Overview
    Worldwide gastric cancer is the 5th most common cancer and the 4th leading cause of cancer deaths. Its highest incidence rates are in east Asia and eastern Europe with low incidence rates in...
    Speaker: Stuti Shroff, MD, MBBS, PhD
    Presented at: Precision Medicine in Solid Tumors
    11
    APR 25, 2023 | 10:00 AM
    Enumeration and Molecular Profiling of Circulating Tumor Cells for Diagnosis and Therapeutic Monitoring of Metastatic Cancer
    Enumeration and Molecular Profiling of Circulating Tumor Cells...
    Date: April 25, 2023 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) A liquid biopsy is a non-invasive alternative to a surgical biopsy that enables researchers to learn a range of infor...
    Speaker: Pravin Potdar
    Sponsored By: Thermo Fisher Scientific
    20 1
    APR 05, 2023 | 9:30 AM
    Optimizing Clone Selection in Cell Line Development with Live Q&A
    Optimizing Clone Selection in Cell Line Development with Live...
    From gene cloning and initial clone selection through to final cell evaluation, the continual assessment of cell count and viability is important for determining the best growing and highest...
    Speaker: Daryl Cole, PhD
    Presented at: Bioprocessing Virtual Event Series 2023
    Sponsored By: Sartorius
    3
    MAR 30, 2023 | 5:00 PM
    Memory-rich CAR-T cell engineering by piggyBac transposon system for solid malignancies
    Memory-rich CAR-T cell engineering by piggyBac transposon system...
    Date: March 30, 2023 Time: 5:00pm (PST), 8:00pm (EST) March 31, 2023 9:00am (JST) Chimeric antigen receptor T cell (CAR-T) therapy is still challenging in targeting solid malignancies. The q...
    Speaker: Dr. Shigeki Yagyu
    Sponsored By: MaxCyte®
    15
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