Cell Line Development: Stable cell lines are widely used in a number of important applications including biologics (e.g. recombinant protein and monoclonal antibody) production, drug screening, and gene functional studies. The process of developing stable cell lines often starts with transfecting selected host cells, typically CHO or HEK 293 cells, with desired plasmids. After transfection, researchers then screen and quantify high-expressing clones. Once these high producers are identified, the cell lines and/or the proteins produced by the cells are validated. The manual screening methods traditionally used for cell line development are time-consuming and labor-intensive, creating a great demand for high-throughput, automated solutions for such efforts.
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Cell line development (CLD) is often a critical bottleneck in biopharmaceutical production, often requiring labor-intensive workflows and multiple sequential screening steps that extend time...
Single cell isolation is a necessary step for a variety of applications from developing productive, stable cell lines for biologics manufacturing to developing CRISPR edited iPSCs for diseas...
The revolution in life science research aims to understand how single cells work, which is crucial for developing new therapies. Traditional methods like FACS and scRNASeq give only a partia...
APR 03, 2024 | 9:00 AM
C.E. CREDITS
Cultured mammalian cells, particularly Chinese hamster ovary (CHO) cells are widely used in the biotechnology industry for production of a wide range of therapeutics, predominantly monoclona...
Luminex and Thermo Fisher Scientific are excited to feature two presentations highlighting the advanced features of the Invitrogen™ Luminex® xMAP® INTELLIFLEX™ DR-SE inst...
Biopharmaceutical manufacturing of proteins requires an efficient cell line. Starting with several thousand clones, researchers use multiple selection rounds to ultimately chose one clone fo...
From drug discovery to organoid modeling of disease, stem cells are increasingly being used in research as a vital tool for scientific investigation. Due to the specialized nature of stem ce...
Embryonic epicardium is crucial for normal heart morphogenesis. The tissue originates from the proepicardial organ, with cells migrating to form the outer mesothelial layer, giving rise to n...
Tumor genomic profiling can be complicated, especially for diseases that commonly have multiple different genomic biomarkers of interest, such as non-small cell lung cancer (NSCLC) and color...
To bring your cutting-edge cell and gene therapies to the patients that need them as quickly as possible, you need access to the most knowledgeable scientists, innovative technologies, metho...
Oxidative stress, a critical factor affecting cell health, has gained prominence in assessing various medical conditions. Given this importance, researchers need a wide range of tools to tho...
Organoids are three-dimensional (3D) multi-cellular, microtissues derived from stem cells that closely mimic the complex structure and functionality of human organs. They offer more accurate...
To bring your cutting-edge cell and gene therapies to the patients that need them as quickly as possible, you need access to the most knowledgeable scientists, innovative technologies, metho...
Organoids are three-dimensional (3D) multi-cellular, microtissues derived from stem cells that closely mimic the complex structure and functionality of human organs. They offer more accurate...
In the ever-evolving landscape of cancer therapy, immune checkpoint inhibitors have emerged as promising avenues for therapeutic antibody development. Our presentation will share GenScript...