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Cell Line Development
Cell Line Development: Stable cell lines are widely used in a number of important applications including biologics (e.g. recombinant protein and monoclonal antibody) production, drug screening, and gene functional studies. The process of developing stable cell lines often starts with transfecting selected host cells, typically CHO or HEK 293 cells, with desired plasmids. After transfection, researchers then screen and quantify high-expressing clones. Once these high producers are identified, the cell lines and/or the proteins produced by the cells are validated. The manual screening methods traditionally used for cell line development are time-consuming and labor-intensive, creating a great demand for high-throughput, automated solutions for such efforts.
JUL 26, 2023 | 12:15 PM
Genetically modified cell models accelerate the development of safe and effective therapeutics, making them indispensable in the quest for new drugs. Through manipulation of cell line geneti...
JUL 18, 2023 2:00 PM EDT
Worldwide gastric cancer is the 5th most common cancer and the 4th leading cause of cancer deaths. Its highest incidence rates are in east Asia and eastern Europe with low incidence rates in...
APR 25, 2023 | 10:00 AM
Date: April 25, 2023 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) A liquid biopsy is a non-invasive alternative to a surgical biopsy that enables researchers to learn a range of infor...
MAR 30, 2023 | 5:00 PM
Date: March 30, 2023 Time: 5:00pm (PST), 8:00pm (EST) March 31, 2023 9:00am (JST) Chimeric antigen receptor T cell (CAR-T) therapy is still challenging in targeting solid malignancies. The q...
MAR 22, 2023 | 9:00 AM
We have developed 3D-shaped hydrogel microparticle platforms to capture cells, as well as isolate and label their secretions. These “lab on a particle” systems enable sorting cel...
FEB 22, 2023 | 12:00 PM
Have you ever tried to access the genomic profiles of cell lines before using them in your preclinical experiments just to come up empty-handed? Maybe you’ve scoured public databases f...
FEB 22, 2023 | 5:30 AM
Many current technologies used in drug discovery and preclinical development programmes typically involve multi-step operations, extensive hands-on time, and lengthy liquid handling processe...
FEB 15, 2023 | 7:00 AM
Date: February 15, 2023 Time: 7:00am (PST), 10:00pm (EST), 4:00pm (CET) While not all microscopy samples can fluoresce, all can scatter light, and this scattered light can be imaged. This ha...
NOV 17, 2022 | 7:00 AM
Date: November 17, 2022 Time: 7:00am (PST), 10:00am (EST), 4:00pm (CET) In order to truly understand cell biology, researchers need easy-to-use tools that preserve the natural complexity of...
NOV 16, 2022 | 10:00 AM
Date: November 16, 2022 Time: 10:00am (PST), 1:00pm (EST), 7:00pm (CET) Eli Lilly, a global healthcare leader, has implemented a next generation research (NGR) initiative to improve the valu...
NOV 16, 2022 | 9:00 AM
Date: November 16, 2022 Time: 9:00am (PST), 12:00pm (EST), 6:00pm (CET) No more estimating. No more ranges. No more uncertainty. While PDX tumor models are crucial for gaining predictive ins...
NOV 08, 2022 | 8:00 AM
Date: November 08, 2022 Time: 8:00am (PST), 11:00am (EST), 5:00pm (CEST) While flow cytometry shines by its flexibility, it requires a high level of expertise in antibody panel development,...
APR 25, 2023 | 10:00 AM
Date: April 25, 2023 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) A liquid biopsy is a non-invasive alternative to a surgical biopsy that enables researchers to learn a range of infor...
MAR 30, 2023 | 5:00 PM
Date: March 30, 2023 Time: 5:00pm (PST), 8:00pm (EST) March 31, 2023 9:00am (JST) Chimeric antigen receptor T cell (CAR-T) therapy is still challenging in targeting solid malignancies. The q...
MAR 22, 2023 | 9:00 AM
We have developed 3D-shaped hydrogel microparticle platforms to capture cells, as well as isolate and label their secretions. These “lab on a particle” systems enable sorting cel...