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    Drug Discovery

    Drug Discovery: drug discovery is the process by which new candidate medications are discovered. Historically, drugs were discovered through identifying the active ingredient from traditional remedies or by serendipitous discovery. Modern drug discovery involves the identification of screening hits, medicinal chemistry and optimization of those hits to increase the affinity, selectivity (to reduce the potential of side effects), efficacy/potency, metabolic stability (to increase the half-life), and oral bioavailability.

    Trending News

    • SEP 16, 2019
      Drug Discovery & Development
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      Injectable Hydrogel Found Safe for Heart Repair
      The first successful in-human clinical trial of an injectable hydrogel that aims to repair heart damage and restore card ...
      Written By: Nouran Amin
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      SEP 15, 2019
      Drug Discovery & Development
      A Diabetic Drug that Promotes Brain Repair...But it Only Works in Females
      A Diabetic Drug that Promotes Brain Repair...But it Only Works in Females
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      SEP 14, 2019
      Drug Discovery & Development
      Does Adderall Really Work for People without ADHD?
      Does Adderall Really Work for People without ADHD?
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      SEP 14, 2019
      Genetics & Genomics
      DNA Construction Kit Could Drive Down Costs of Immune Therapy
      DNA Construction Kit Could Drive Down Costs of Immune Therapy
      Researchers at KU Leuven in Belgium have created a DNA construction kit that, when injected into muscle cells, enables s ...
      Written By: Annie Lennon
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      SEP 13, 2019
      Cancer
      Cancer drugs don't work the way we thought
      Cancer drugs don't work the way we thought
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      SEP 11, 2019
      Drug Discovery & Development
      Insulin Drug Could Treat Glioblastoma
      Insulin Drug Could Treat Glioblastoma
      A molecule used for drug delivery of insulin was recently found by researchers at the University of Georgia’s Rege ...
      Written By: Nouran Amin
      1
      SEP 10, 2019
      Drug Discovery & Development
      Does Modafinil Really Increase Brain Function?
      Does Modafinil Really Increase Brain Function?
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      SEP 09, 2019
      Drug Discovery & Development
      Diabetic Drugs Offer Protection Against Kidney Failure
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      Kidney failure is a consequence of diabetic kidney disease--roughly 3 million people are seeking treatment worldwide for ...
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      SEP 09, 2019
      Drug Discovery & Development
      Do Nootropics Really Boost Brain Function?
      Do Nootropics Really Boost Brain Function?
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      Written By: Annie Lennon
      1
      SEP 08, 2019
      Cannabis Sciences
      Why Does Cannabis Help Arthritis?
      Why Does Cannabis Help Arthritis?
      One of the main health claims for marijuana is rheumatoid arthritis (RA). If marijuana acts to alleviate symptoms of rhe ...
      Written By: Amy Loriaux
      1
      SEP 07, 2019
      Cell & Molecular Biology
      Scientists Reveal how Pancreatic Cancer Evades Chemotherapy
      Scientists Reveal how Pancreatic Cancer Evades Chemotherapy
      Scientists at the University of Pennsylvania reveal answers to help better treat pancreatic cancer in the future.
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      SEP 07, 2019
      Immunology
      A New Way To Fight Severe Peanut Allergies
      A New Way To Fight Severe Peanut Allergies
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      SEP 06, 2019
      Drug Discovery & Development
      The Three Drugs that Reverse Biological Aging
      The Three Drugs that Reverse Biological Aging
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      SEP 05, 2019
      Clinical & Molecular DX
      Muscular Dystrophy Drug by Sarepta Therapeutics: Approval or Rejection by Drug Regulating Authorities?
      Muscular Dystrophy Drug by Sarepta Therapeutics: Approval or Rejection by Drug Regulating Authorities?
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      SEP 05, 2019
      Cell & Molecular Biology
      How the Kava Plant Creates Medicinal Compounds
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      SEP 04, 2019
      Drug Discovery & Development
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      SEP 03, 2019
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      SEP 02, 2019
      Drug Discovery & Development
      Standard Treatment Resistance Discovered in Crohn's Disease
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      AUG 29, 2019
      Drug Discovery & Development
      Can FDA Approved Ketamine Drug Spravato Really Treat Depression?
      Can FDA Approved Ketamine Drug Spravato Really Treat Depression?
      President Trump is allegedly in support of a new drug to combat depression. He even urged the Department of Veterans Aff ...
      Written By: Annie Lennon
      1
      AUG 27, 2019
      Drug Discovery & Development
      Why Drugs that Work on Mice Don't Work on Humans
      Why Drugs that Work on Mice Don't Work on Humans
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      Written By: Annie Lennon
      1
      AUG 27, 2019
      Health & Medicine
      A Skin Patch Might be the Most Effective Melanoma Treatment
      A Skin Patch Might be the Most Effective Melanoma Treatment
      Researchers from the Massachusetts Institute of Technology (MIT) have developed a fast-acting skin patch that effectivel ...
      Written By: Tiffany Dazet
      1
      AUG 26, 2019
      Genetics & Genomics
      New Gene Editing Technology to Combat Hereditary Diseases
      New Gene Editing Technology to Combat Hereditary Diseases
      Until recently, many types of gene-editing methods were unable to target critical parts of DNA. Now however, researchers ...
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      AUG 25, 2019
      Drug Discovery & Development
      Unprecedented Therapeutic Found Effective for Blood Cancer
      Unprecedented Therapeutic Found Effective for Blood Cancer
      According to the findings of a clinical trial, scientists at Mt. Sinai have found a new therapeutic effective for p ...
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      AUG 25, 2019
      Technology
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      Computer Model Advances New Therapeutics for Sickle Cell Anemia
      A team of Brown University researchers has developed a new computer model that simulates the way red blood cells become ...
      Written By: Nouran Amin
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    SEP 16, 2019
    Drug Discovery & Development
    Injectable Hydrogel Found Safe for Heart Repair
    Injectable Hydrogel Found Safe for Heart Repair
    The first successful in-human clinical trial of an injectable hydrogel that aims to repair heart damage and restore card ...
    Written By: Nouran Amin
    1
    SEP 15, 2019
    Drug Discovery & Development
    A Diabetic Drug that Promotes Brain Repair...But it Only Works in Females
    A Diabetic Drug that Promotes Brain Repair...But it Only Works in Females
    Gender discrimination in research has long stopped serious advancements. In neuroscience, scientists believed that male ...
    Written By: Nouran Amin
    1
    SEP 14, 2019
    Drug Discovery & Development
    Does Adderall Really Work for People without ADHD?
    Does Adderall Really Work for People without ADHD?
    Adderall is a popular stimulant. Known to treat Attention Deficit Disorder (ADHD), those without the condition also use ...
    Written By: Annie Lennon
    1
    SEP 14, 2019
    Genetics & Genomics
    DNA Construction Kit Could Drive Down Costs of Immune Therapy
    DNA Construction Kit Could Drive Down Costs of Immune Therapy
    Researchers at KU Leuven in Belgium have created a DNA construction kit that, when injected into muscle cells, enables s ...
    Written By: Annie Lennon
    1
    SEP 13, 2019
    Cancer
    Cancer drugs don't work the way we thought
    Cancer drugs don't work the way we thought
    New research recently published in the journal Science Translational Medicine surprises the oncological community with f ...
    Written By: Kathryn DeMuth Sullivan
    2 1
     
     
  • SEP 11, 2019
    Drug Discovery & Development
    Insulin Drug Could Treat Glioblastoma
    Insulin Drug Could Treat Glioblastoma
    A molecule used for drug delivery of insulin was recently found by researchers at the University of Georgia’s Rege ...
    Written By: Nouran Amin
    1
    SEP 10, 2019
    Drug Discovery & Development
    Does Modafinil Really Increase Brain Function?
    Does Modafinil Really Increase Brain Function?
    Modafinil, often sold under the name “Provigil”, is a wakefulness-promoting drug used to treat excessive sle ...
    Written By: Annie Lennon
    1
    SEP 09, 2019
    Drug Discovery & Development
    Diabetic Drugs Offer Protection Against Kidney Failure
    Diabetic Drugs Offer Protection Against Kidney Failure
    Kidney failure is a consequence of diabetic kidney disease--roughly 3 million people are seeking treatment worldwide for ...
    Written By: Nouran Amin
    1
    SEP 09, 2019
    Drug Discovery & Development
    Do Nootropics Really Boost Brain Function?
    Do Nootropics Really Boost Brain Function?
      Nootropics are a broad range of both natural and artificial compounds though to improve cognitive function. Inclu ...
    Written By: Annie Lennon
    1
    SEP 08, 2019
    Cannabis Sciences
    Why Does Cannabis Help Arthritis?
    Why Does Cannabis Help Arthritis?
    One of the main health claims for marijuana is rheumatoid arthritis (RA). If marijuana acts to alleviate symptoms of rhe ...
    Written By: Amy Loriaux
    1
     
     
  • SEP 07, 2019
    Cell & Molecular Biology
    Scientists Reveal how Pancreatic Cancer Evades Chemotherapy
    Scientists Reveal how Pancreatic Cancer Evades Chemotherapy
    Scientists at the University of Pennsylvania reveal answers to help better treat pancreatic cancer in the future.
    Written By: Carly Boyd
    1
    SEP 07, 2019
    Immunology
    A New Way To Fight Severe Peanut Allergies
    A New Way To Fight Severe Peanut Allergies
    Dr. Sandra Lin explains how SLIT is currently being used to treat allergies other than peanuts.    Over 1 mill ...
    Written By: Amanda Mikyska
    1
    SEP 06, 2019
    Drug Discovery & Development
    The Three Drugs that Reverse Biological Aging
    The Three Drugs that Reverse Biological Aging
    In the last 100 years, life expectancy in the US has risen from 55 years until 79 (Roser: 2019). And with the continuous ...
    Written By: Annie Lennon
    3
    SEP 05, 2019
    Clinical & Molecular DX
    Muscular Dystrophy Drug by Sarepta Therapeutics: Approval or Rejection by Drug Regulating Authorities?
    Muscular Dystrophy Drug by Sarepta Therapeutics: Approval or Rejection by Drug Regulating Authorities?
    Duchenne Muscular Dystrophy (DMD is a rare, genetic disorder that hampers muscle movement and is the most common pediatr ...
    Written By: Nupur Srivastava
    1
    SEP 05, 2019
    Cell & Molecular Biology
    How the Kava Plant Creates Medicinal Compounds
    How the Kava Plant Creates Medicinal Compounds
    Nature has given us some of our best medicines; it's thought that as many as half the drugs we used are derived from nat ...
    Written By: Carmen Leitch
    1
     
     
  • SEP 04, 2019
    Drug Discovery & Development
    Re-Evaluating a Popular Heart Failure Drug
    Re-Evaluating a Popular Heart Failure Drug
    A recent study found that the popular heart drug--sacubitril/valsartan—holds positive effects on the structure and ...
    Written By: Nouran Amin
    1
    SEP 03, 2019
    Cardiology
    Somethings Fishy With Omega 3 Claims
    Somethings Fishy With Omega 3 Claims
    Each month nearly 20 million Americans turn to fish oil for heart disease prevention. Though it may sound healthy, this ...
    Written By: Abbie Arce
    1
    SEP 02, 2019
    Drug Discovery & Development
    Standard Treatment Resistance Discovered in Crohn's Disease
    Standard Treatment Resistance Discovered in Crohn's Disease
    Researchers have mapped out more than 100,000 immune cells from biopsy samples of patients with Crohn's disease. The ...
    Written By: Nouran Amin
    1
    AUG 29, 2019
    Drug Discovery & Development
    Can FDA Approved Ketamine Drug Spravato Really Treat Depression?
    Can FDA Approved Ketamine Drug Spravato Really Treat Depression?
    President Trump is allegedly in support of a new drug to combat depression. He even urged the Department of Veterans Aff ...
    Written By: Annie Lennon
    1
    AUG 27, 2019
    Drug Discovery & Development
    Why Drugs that Work on Mice Don't Work on Humans
    Why Drugs that Work on Mice Don't Work on Humans
    Mice are used as the frontline for drug testing for brain disorders. Why? Their brains are supposed to have much of the ...
    Written By: Annie Lennon
    1
     
     
  • AUG 27, 2019
    Health & Medicine
    A Skin Patch Might be the Most Effective Melanoma Treatment
    A Skin Patch Might be the Most Effective Melanoma Treatment
    Researchers from the Massachusetts Institute of Technology (MIT) have developed a fast-acting skin patch that effectivel ...
    Written By: Tiffany Dazet
    1
    AUG 26, 2019
    Genetics & Genomics
    New Gene Editing Technology to Combat Hereditary Diseases
    New Gene Editing Technology to Combat Hereditary Diseases
    Until recently, many types of gene-editing methods were unable to target critical parts of DNA. Now however, researchers ...
    Written By: Annie Lennon
    2
    AUG 25, 2019
    Drug Discovery & Development
    Unprecedented Therapeutic Found Effective for Blood Cancer
    Unprecedented Therapeutic Found Effective for Blood Cancer
    According to the findings of a clinical trial, scientists at Mt. Sinai have found a new therapeutic effective for p ...
    Written By: Nouran Amin
    1
    AUG 25, 2019
    Technology
    Computer Model Advances New Therapeutics for Sickle Cell Anemia
    Computer Model Advances New Therapeutics for Sickle Cell Anemia
    A team of Brown University researchers has developed a new computer model that simulates the way red blood cells become ...
    Written By: Nouran Amin
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