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    Drug Discovery

    Drug Discovery: drug discovery is the process by which new candidate medications are discovered. Historically, drugs were discovered through identifying the active ingredient from traditional remedies or by serendipitous discovery. Modern drug discovery involves the identification of screening hits, medicinal chemistry and optimization of those hits to increase the affinity, selectivity (to reduce the potential of side effects), efficacy/potency, metabolic stability (to increase the half-life), and oral bioavailability.

    Trending News

    • AUG 25, 2019
      Drug Discovery & Development
      Comparison of Three Frontline Breast Cancer Drugs
      Comparison of Three Frontline Breast Cancer Drugs
      Breast cancer affects 250,000 women in the U.S. annually. Those with most common form test positive for hormone receptor ...
      Written By: Nouran Amin
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      AUG 25, 2019
      Technology
      How Bitcoins Can Advance Medication Usage
      How Bitcoins Can Advance Medication Usage
      Will futuristic concepts from the world of technology likely find a place in our medicine cabinet? Maybe! The new concep ...
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      AUG 23, 2019
      Clinical & Molecular DX
      Are Anti-Ebola Drugs Effective?
      Are Anti-Ebola Drugs Effective?
      A deadly Ebola Virus Disease (EVD) caused by the Ebola virus triggers hemorrhagic fever in humans and some monkeys. The ...
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      AUG 23, 2019
      Immunology
      Making Opioids Safer
      Making Opioids Safer
      The opioid crisis results in 130 American deaths every day, and both prescribed and synthetic opioids are at the core of ...
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      AUG 23, 2019
      Cancer
      New hope for children's brain cancer DIPG
      New hope for children's brain cancer DIPG
      New research published in Nature Communications provides insight on a potential treatment for an aggressive form of brai ...
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      AUG 22, 2019
      Drug Discovery & Development
      Scientists Grow Mini Kidneys to Treat Kidney Disease
      Scientists Grow Mini Kidneys to Treat Kidney Disease
      Current methods for testing potential treatments for kidney disease do not take genetic variation into account for how t ...
      Written By: Annie Lennon
      1
      AUG 20, 2019
      Neuroscience
      Scientists discover new pain-sensing organ in skin
      Scientists discover new pain-sensing organ in skin
      Schwann cells are octopus-like cells in the nervous system that wrap around nerve cells, jelly-roll fashion, to form a s ...
      Written By: Dr. Nina Lichtenberg
      1
      AUG 20, 2019
      Drug Discovery & Development
      What's the Difference Between Therapy and MDMA Therapy?
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      AUG 20, 2019
      Drug Discovery & Development
      Lab-on-a-chip Advances Search for Anti-Clotting Drugs
      Lab-on-a-chip Advances Search for Anti-Clotting Drugs
      A novel ‘lab-on-a-chip’ the size of a postage stamp could soon advance the developments of safer anti-clotti ...
      Written By: Nouran Amin
      1
      AUG 19, 2019
      Drug Discovery & Development
      MDMA Treats Social Anxiety in Autistic Adults
      MDMA Treats Social Anxiety in Autistic Adults
      People with autism are more likely than those without to develop social anxiety (Bejerot: 2014). Meanwhile, current anti ...
      Written By: Annie Lennon
      1
      AUG 19, 2019
      Health & Medicine
      FDA Approves New Treatment for Extensively Drug-Resistant TB
      FDA Approves New Treatment for Extensively Drug-Resistant TB
      Last week, the U.S. Food and Drug Administration (FDA) approved a new treatment for a severe form of multi-drug-resistan ...
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      AUG 19, 2019
      Drug Discovery & Development
      What does MDMA Therapy Look Like?
      What does MDMA Therapy Look Like?
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      AUG 18, 2019
      Microbiology
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      The Long Evolutionary History of Antibiotics and Resistance
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      AUG 17, 2019
      Drug Discovery & Development
      How Does Ecstasy Treat PTSD?
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      AUG 17, 2019
      Chemistry & Physics
      Chemists Synthesized Effective Antidote For Uranium Poisoning
      Chemists Synthesized Effective Antidote For Uranium Poisoning
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      AUG 15, 2019
      Drug Discovery & Development
      Drug Targets Early Instigators of Alzheimer Disease
      Drug Targets Early Instigators of Alzheimer Disease
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      AUG 14, 2019
      Drug Discovery & Development
      Promising Drug Encourages Survival in Pancreatic Cancer
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      AUG 13, 2019
      Health & Medicine
      Blood-Brain Barrier Impairment and Its Role in Alzheimer's Disease
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      1
      AUG 13, 2019
      Drug Discovery & Development
      Aspirin: The Good and Bad for Breast Cancer Survivors
      Aspirin: The Good and Bad for Breast Cancer Survivors
      Early research has indicated that aspirin usage may increase the survival rate among women with breast cancer. These stu ...
      Written By: Nouran Amin
      1
      AUG 13, 2019
      Drug Discovery & Development
      Novel Drug Target for Dilating Microvessels
      Novel Drug Target for Dilating Microvessels
      Medical scientists at Augusta University have discovered a natural occurring chemical that dilates blood vessels dilate ...
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      AUG 12, 2019
      Drug Discovery & Development
      Can Psychedelics Treat Alcoholism?
      Can Psychedelics Treat Alcoholism?
      Some of the first research on psychedelics in clinical settings was to assess their efficacy in treating alcoholism. In ...
      Written By: Annie Lennon
      1
      AUG 11, 2019
      Cell & Molecular Biology
      Stopping Metastasis After Breast Cancer Surgery
      Stopping Metastasis After Breast Cancer Surgery
      Cancer is most deadly when it metastasizes, which can happen after tumor-removal surgery. It's a serious challenge for m ...
      Written By: Carmen Leitch
      2
      AUG 11, 2019
      Microbiology
      Picturing a New Kind of Antibiotic
      Picturing a New Kind of Antibiotic
      Scientists have deciphered the X-ray crystal structure of an enzyme that generates a unique broad spectrum antibiotic ca ...
      Written By: Carmen Leitch
      1
      AUG 10, 2019
      Drug Discovery & Development
      Can LSD Treat Addiction?
      Can LSD Treat Addiction?
      Modern medicine commonly refers to addiction as a brain disease caused by drugs and other negative stimuli. However, evi ...
      Written By: Annie Lennon
      1
    AUG 25, 2019
    Drug Discovery & Development
    Comparison of Three Frontline Breast Cancer Drugs
    Comparison of Three Frontline Breast Cancer Drugs
    Breast cancer affects 250,000 women in the U.S. annually. Those with most common form test positive for hormone receptor ...
    Written By: Nouran Amin
    1
    AUG 25, 2019
    Technology
    How Bitcoins Can Advance Medication Usage
    How Bitcoins Can Advance Medication Usage
    Will futuristic concepts from the world of technology likely find a place in our medicine cabinet? Maybe! The new concep ...
    Written By: Nouran Amin
    1
    AUG 23, 2019
    Clinical & Molecular DX
    Are Anti-Ebola Drugs Effective?
    Are Anti-Ebola Drugs Effective?
    A deadly Ebola Virus Disease (EVD) caused by the Ebola virus triggers hemorrhagic fever in humans and some monkeys. The ...
    Written By: Nupur Srivastava
    2
    AUG 23, 2019
    Immunology
    Making Opioids Safer
    Making Opioids Safer
    The opioid crisis results in 130 American deaths every day, and both prescribed and synthetic opioids are at the core of ...
    Written By: Amanda Mikyska
    1
    AUG 23, 2019
    Cancer
    New hope for children's brain cancer DIPG
    New hope for children's brain cancer DIPG
    New research published in Nature Communications provides insight on a potential treatment for an aggressive form of brai ...
    Written By: Kathryn DeMuth Sullivan
    2
     
     
  • AUG 22, 2019
    Drug Discovery & Development
    Scientists Grow Mini Kidneys to Treat Kidney Disease
    Scientists Grow Mini Kidneys to Treat Kidney Disease
    Current methods for testing potential treatments for kidney disease do not take genetic variation into account for how t ...
    Written By: Annie Lennon
    1
    AUG 20, 2019
    Neuroscience
    Scientists discover new pain-sensing organ in skin
    Scientists discover new pain-sensing organ in skin
    Schwann cells are octopus-like cells in the nervous system that wrap around nerve cells, jelly-roll fashion, to form a s ...
    Written By: Dr. Nina Lichtenberg
    1
    AUG 20, 2019
    Drug Discovery & Development
    What's the Difference Between Therapy and MDMA Therapy?
    What's the Difference Between Therapy and MDMA Therapy?
    From a first glance, MDMA-assisted therapy may look very different from mainstream therapies such as Cognitive Behaviora ...
    Written By: Annie Lennon
    2
    AUG 20, 2019
    Drug Discovery & Development
    Lab-on-a-chip Advances Search for Anti-Clotting Drugs
    Lab-on-a-chip Advances Search for Anti-Clotting Drugs
    A novel ‘lab-on-a-chip’ the size of a postage stamp could soon advance the developments of safer anti-clotti ...
    Written By: Nouran Amin
    1
    AUG 19, 2019
    Drug Discovery & Development
    MDMA Treats Social Anxiety in Autistic Adults
    MDMA Treats Social Anxiety in Autistic Adults
    People with autism are more likely than those without to develop social anxiety (Bejerot: 2014). Meanwhile, current anti ...
    Written By: Annie Lennon
    1
     
     
  • AUG 19, 2019
    Health & Medicine
    FDA Approves New Treatment for Extensively Drug-Resistant TB
    FDA Approves New Treatment for Extensively Drug-Resistant TB
    Last week, the U.S. Food and Drug Administration (FDA) approved a new treatment for a severe form of multi-drug-resistan ...
    Written By: Tiffany Dazet
    1
    AUG 19, 2019
    Drug Discovery & Development
    What does MDMA Therapy Look Like?
    What does MDMA Therapy Look Like?
    The Multidisciplinary Association for Psychedelic Studies (MAPS) aims to create an FDA-approved standardized MDMA-assist ...
    Written By: Annie Lennon
    1
    AUG 18, 2019
    Microbiology
    The Long Evolutionary History of Antibiotics and Resistance
    The Long Evolutionary History of Antibiotics and Resistance
    The world is full of bacteria that have to share the world with myriad species, and often have to live in competition wi ...
    Written By: Carmen Leitch
    1
    AUG 17, 2019
    Drug Discovery & Development
    How Does Ecstasy Treat PTSD?
    How Does Ecstasy Treat PTSD?
    Conventionally, Post Traumatic Stress Disorder (PTSD) is treated via talk therapy, with the aim of getting patients to o ...
    Written By: Annie Lennon
    1
    AUG 17, 2019
    Chemistry & Physics
    Chemists Synthesized Effective Antidote For Uranium Poisoning
    Chemists Synthesized Effective Antidote For Uranium Poisoning
    Uranium poisoning is unusual to the general population but does happen to miners, mineral mill and fabrication workers. ...
    Written By: Daniel Duan
    1
     
     
  • AUG 15, 2019
    Drug Discovery & Development
    Drug Targets Early Instigators of Alzheimer Disease
    Drug Targets Early Instigators of Alzheimer Disease
    The two solidifying instigators of Alzheimer -disease (AD)—amyloid beta and the tau protein—have long been t ...
    Written By: Nouran Amin
    1
    AUG 14, 2019
    Drug Discovery & Development
    Promising Drug Encourages Survival in Pancreatic Cancer
    Promising Drug Encourages Survival in Pancreatic Cancer
    Building on almost 20 years of research, a phase 1 clinical trial drug for pancreatic cancer, named ‘AZD1775&rsquo ...
    Written By: Nouran Amin
    2
    AUG 13, 2019
    Health & Medicine
    Blood-Brain Barrier Impairment and Its Role in Alzheimer's Disease
    Blood-Brain Barrier Impairment and Its Role in Alzheimer's Disease
    In healthy people, the blood-brain barrier (BBB), which is fromed by brain endothelial cells, strictly controls the ...
    Written By: Dena Aruta
    1
    AUG 13, 2019
    Drug Discovery & Development
    Aspirin: The Good and Bad for Breast Cancer Survivors
    Aspirin: The Good and Bad for Breast Cancer Survivors
    Early research has indicated that aspirin usage may increase the survival rate among women with breast cancer. These stu ...
    Written By: Nouran Amin
    1
    AUG 13, 2019
    Drug Discovery & Development
    Novel Drug Target for Dilating Microvessels
    Novel Drug Target for Dilating Microvessels
    Medical scientists at Augusta University have discovered a natural occurring chemical that dilates blood vessels dilate ...
    Written By: Nouran Amin
    1
     
     
  • AUG 12, 2019
    Drug Discovery & Development
    Can Psychedelics Treat Alcoholism?
    Can Psychedelics Treat Alcoholism?
    Some of the first research on psychedelics in clinical settings was to assess their efficacy in treating alcoholism. In ...
    Written By: Annie Lennon
    1
    AUG 11, 2019
    Cell & Molecular Biology
    Stopping Metastasis After Breast Cancer Surgery
    Stopping Metastasis After Breast Cancer Surgery
    Cancer is most deadly when it metastasizes, which can happen after tumor-removal surgery. It's a serious challenge for m ...
    Written By: Carmen Leitch
    2
    AUG 11, 2019
    Microbiology
    Picturing a New Kind of Antibiotic
    Picturing a New Kind of Antibiotic
    Scientists have deciphered the X-ray crystal structure of an enzyme that generates a unique broad spectrum antibiotic ca ...
    Written By: Carmen Leitch
    1
    AUG 10, 2019
    Drug Discovery & Development
    Can LSD Treat Addiction?
    Can LSD Treat Addiction?
    Modern medicine commonly refers to addiction as a brain disease caused by drugs and other negative stimuli. However, evi ...
    Written By: Annie Lennon
    1
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