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    Drug Discovery

    Drug Discovery: drug discovery is the process by which new candidate medications are discovered. Historically, drugs were discovered through identifying the active ingredient from traditional remedies or by serendipitous discovery. Modern drug discovery involves the identification of screening hits, medicinal chemistry and optimization of those hits to increase the affinity, selectivity (to reduce the potential of side effects), efficacy/potency, metabolic stability (to increase the half-life), and oral bioavailability.

    Trending News

    • MAR 10, 2019
      Drug Discovery & Development
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      Can Green Tea Reverse Memory Impairment?
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      MAR 10, 2019
      Microbiology
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      Bacteria on Frog Skin Can Help Fight Fungal Infections
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      MAR 09, 2019
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      MAR 03, 2019
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      Drug Reverses Effects of Alcohol on the Brain
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      MAR 01, 2019
      Drug Discovery & Development
      Nicotine on Human Embryonic Development
      Nicotine on Human Embryonic Development
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      FEB 27, 2019
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      FEB 25, 2019
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      ADHD Drug Holds No Effect on Primate Prefrontal Cortex
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      FEB 25, 2019
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      FEB 25, 2019
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      FEB 25, 2019
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      Photoelectrochemical Cells To Produce New Drug Discovery Molecules
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      FEB 24, 2019
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      FEB 21, 2019
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      FEB 21, 2019
      Cannabis Sciences
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      FEB 21, 2019
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      FEB 20, 2019
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      FEB 20, 2019
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      FEB 17, 2019
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      FEB 17, 2019
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      FEB 17, 2019
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      Drug Combination May Become Standard Treatment for Metastatic Kidney Cancer
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      FEB 17, 2019
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      Pain.
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      FEB 11, 2019
      Chemistry & Physics
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      FEB 08, 2019
      Drug Discovery & Development
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      Researchers at University of Technology Sydney warn that the protein supplement, L-norvaline, could damage brain cells. ...
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      FEB 08, 2019
      Drug Discovery & Development
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      FEB 08, 2019
      Drug Discovery & Development
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      Drug Combination Generates New Neurons from Neighboring Cells
      In a study published in Stem Cell Reports, scientists at Penn State University have developed a drug cocktail that conve ...
      Written By: Nouran Amin
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    MAR 10, 2019
    Drug Discovery & Development
    Can Green Tea Reverse Memory Impairment?
    Can Green Tea Reverse Memory Impairment?
    In a study published in the Journal of Biological Chemistry, a diet containing green tea and carrots reversed Alzheimer& ...
    Written By: Nouran Amin
    1
    MAR 10, 2019
    Microbiology
    Bacteria on Frog Skin Can Help Fight Fungal Infections
    Bacteria on Frog Skin Can Help Fight Fungal Infections
    In recent years, fungal disease has decimated amphibian populations; some species went extinct. But others withstood the ...
    Written By: Carmen Leitch
    1
    MAR 09, 2019
    Videos
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    In 1928, Alexander Fleming found a contaminated Petri dish, and from there, humanity's use of antibiotics started.
    Written By: Carmen Leitch
    2
    MAR 03, 2019
    Drug Discovery & Development
    Drug Reverses Effects of Alcohol on the Brain
    Drug Reverses Effects of Alcohol on the Brain
    Recently, researchers have identified a drug that could help reverse the damaging effects of heavy alcohol consumption o ...
    Written By: Nouran Amin
    2
    MAR 01, 2019
    Drug Discovery & Development
    Nicotine on Human Embryonic Development
    Nicotine on Human Embryonic Development
    Researchers report in a study published in the journal Stem Cell Reports, that nicotine exerted adverse effects on human ...
    Written By: Nouran Amin
    2
     
     
  • FEB 27, 2019
    Immunology
    Anti-Inflammatory Meds without Side Effects, Please
    Anti-Inflammatory Meds without Side Effects, Please
    Drugs such as ibuprofen or aspirin that relieve pain and lower fever are among the most frequently used drugs worldwide.
    Written By: Nicholas Breehl
    4
    FEB 25, 2019
    Drug Discovery & Development
    ADHD Drug Holds No Effect on Primate Prefrontal Cortex
    ADHD Drug Holds No Effect on Primate Prefrontal Cortex
    According to a new research study published eNeuro, investigations of methylphenidate (Ritalin) on neuronal activity in ...
    Written By: Nouran Amin
    1
    FEB 25, 2019
    Drug Discovery & Development
    3D Hydrogel Advances Drug Discovery
    3D Hydrogel Advances Drug Discovery
    Researchers have developed a 3D hydrogel based on hyaluronic acid, a biocompatible substance. The gel could quickly and ...
    Written By: Nouran Amin
    1
    FEB 25, 2019
    Drug Discovery & Development
    Open-Science Model Advances Drug Discovery
    Open-Science Model Advances Drug Discovery
    Parkinson’s disease and Amyotrophic Lateral Sclerosis is the latest push for Medicines 4 Neurodegenerative Disease ...
    Written By: Nouran Amin
    1
    FEB 25, 2019
    Drug Discovery & Development
    Photoelectrochemical Cells To Produce New Drug Discovery Molecules
    Photoelectrochemical Cells To Produce New Drug Discovery Molecules
    Photoelectrochemical (PEC) cells utilize photocathodes and photoanodes to "split" water into hydrogen and oxyg ...
    Written By: Nouran Amin
    1
     
     
  • FEB 24, 2019
    Drug Discovery & Development
    Possible Therapeutic for Duchenne Muscular Dystrophy (DMD)
    Possible Therapeutic for Duchenne Muscular Dystrophy (DMD)
    Individuals diagnosed with Duchenne muscular dystrophy (DMD) face few treatment options. DMD is a progressive muscle wea ...
    Written By: Nouran Amin
    2
    FEB 21, 2019
    Genetics & Genomics
    How High-fat Diets may be Driving a Rise in Colon Cancer
    How High-fat Diets may be Driving a Rise in Colon Cancer
    While cancer rates are dropping in general, colorectal cancer is becoming more common in people under the age of 55.
    Written By: Carmen Leitch
    2
    FEB 21, 2019
    Cannabis Sciences
    Cannabis 101: Now Accepting Students
    Cannabis 101: Now Accepting Students
    Michigan voters recently legalized recreational cannabis. A few months later, PharmSci 420 (I'm serious, that is the ...
    Written By: Amy Loriaux
    1
    FEB 21, 2019
    Health & Medicine
    Getting A Second Opinion
    Getting A Second Opinion
    If you have been handed down to her diagnosis from your doctor and you are considering asking for a second opinion, you ...
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    1
    FEB 20, 2019
    Drug Discovery & Development
    Possible New Drug To Combat African Sleeping Sickness
    Possible New Drug To Combat African Sleeping Sickness
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    Written By: Nouran Amin
    2
     
     
  • FEB 20, 2019
    Drug Discovery & Development
    Cocktail of Common Antibiotics Fights E. coli Infections
    Cocktail of Common Antibiotics Fights E. coli Infections
    Researchers at the Technical University of Denmark are working towards finding new methods for battling antibiotic resis ...
    Written By: Nouran Amin
    1
    FEB 17, 2019
    Drug Discovery & Development
    Dangers of an OTC Diarrhea Medication
    Dangers of an OTC Diarrhea Medication
    A recent study by Rutgers University found that overdosing on loperamide—a non-prescription, over-the-counter diar ...
    Written By: Nouran Amin
    1
    FEB 17, 2019
    Drug Discovery & Development
    Drug Improves Muscle Properties
    Drug Improves Muscle Properties
    Currently, adults over 65 are an increasingly growing segment in many countries. In the United States, the elderly popul ...
    Written By: Nouran Amin
    1 1
    FEB 17, 2019
    Drug Discovery & Development
    Drug Combination May Become Standard Treatment for Metastatic Kidney Cancer
    Drug Combination May Become Standard Treatment for Metastatic Kidney Cancer
    Reporting from results of a phase 3 clinical trial, patients with metastatic kidney cancer may soon receive a new standa ...
    Written By: Nouran Amin
    1
    FEB 17, 2019
    Neuroscience
    Scientists Find First Biomarker for Pain
    Scientists Find First Biomarker for Pain
    Pain.
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    2
     
     
  • FEB 11, 2019
    Chemistry & Physics
    Actinium-based Targeted Alpha Therapy Delivers A Combo Punch
    Actinium-based Targeted Alpha Therapy Delivers A Combo Punch
    Radiotherapy is a staple among many medical interventions to treat cancer. Besides external beam radiotherapy and sealed ...
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    1
    FEB 08, 2019
    Drug Discovery & Development
    Bodybuilding Supplement Harms Brain Cells
    Bodybuilding Supplement Harms Brain Cells
    Researchers at University of Technology Sydney warn that the protein supplement, L-norvaline, could damage brain cells. ...
    Written By: Nouran Amin
    3
    FEB 08, 2019
    Drug Discovery & Development
    Apsirin Use Prevents Colorectal Cancer
    Apsirin Use Prevents Colorectal Cancer
    In a study published in the American Journal of Medicine, the U.S. Preventive Services Task Force (USPSTF) concluded tha ...
    Written By: Nouran Amin
    1
    FEB 08, 2019
    Drug Discovery & Development
    Drug Combination Generates New Neurons from Neighboring Cells
    Drug Combination Generates New Neurons from Neighboring Cells
    In a study published in Stem Cell Reports, scientists at Penn State University have developed a drug cocktail that conve ...
    Written By: Nouran Amin
    2
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