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    Drug Discovery

    Drug Discovery: drug discovery is the process by which new candidate medications are discovered. Historically, drugs were discovered through identifying the active ingredient from traditional remedies or by serendipitous discovery. Modern drug discovery involves the identification of screening hits, medicinal chemistry and optimization of those hits to increase the affinity, selectivity (to reduce the potential of side effects), efficacy/potency, metabolic stability (to increase the half-life), and oral bioavailability.

    Trending News

    • DEC 01, 2021
      Drug Discovery & Development
      Researchers develop a novel drug that can combat diabetic tissue damage
      Researchers develop a novel drug that can combat diabetic tissue damage
      Diabetes is a common disease that occurs when high levels of blood sugar start to silently damage bodily tissue and orga ...
      Written By: J. Bryce Ortiz
      1
      NOV 30, 2021
      Cannabis Sciences
      To Trust or Not to Trust the Process: Bioreactive Chemical Variation in Cannabis Extracts Based on Extraction Method
      To Trust or Not to Trust the Process: Bioreactive Chemical Variation in Cannabis Extracts Based on Extraction Method
      With cannabis legislation becoming increasingly less restrictive over the past 20 years, consumers have found themselves ...
      Written By: Nadine Husami
      1
      NOV 30, 2021
      Cannabis Sciences
      Terpene-Mediated Modulation of Cannabinoid Activity
      Terpene-Mediated Modulation of Cannabinoid Activity
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      1
      NOV 30, 2021
      Immunology
      Sweet Escape: A Sugar Molecule Helps HIV Remain Incognito
      Sweet Escape: A Sugar Molecule Helps HIV Remain Incognito
      HIV is a master of disguise. Once the virus enters the body, it has a number of sophisticated mechanisms through which i ...
      Written By: Tara Fernandes
      1
      NOV 30, 2021
      Drug Discovery & Development
      Enabling new levels of quantification with the SCIEX 7500 system - powered by SCIEX OS Software
      Enabling new levels of quantification with the SCIEX 7500 system - powered by SCIEX OS Software
      Sensitivity is a fundamental performance characteristic of a mass spectrometer The SCIEX 7500 system is enabling new lev ...
      Written By: SCIEX Le
      1
      NOV 29, 2021
      Genetics & Genomics
      A CRISPR-Based Technique to Make New Antibiotics
      A CRISPR-Based Technique to Make New Antibiotics
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      NOV 29, 2021
      Cancer
      An Amino Acid Can Improve Radiation Therapy for Metastatic Brain Cancer
      An Amino Acid Can Improve Radiation Therapy for Metastatic Brain Cancer
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      NOV 25, 2021
      Microbiology
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      How Microbes Use Copper to Make an Antibiotic
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      NOV 25, 2021
      Immunology
      Battling Bacterial Pneumonia, No Antibiotics Required
      Battling Bacterial Pneumonia, No Antibiotics Required
      Instead of flooding the body with antibiotics, what if we could program cells to fight off pathogens more effectively? T ...
      Written By: Tara Fernandes
      1
      NOV 25, 2021
      Immunology
      What's a T Cell COVID Vaccine and Could It Be Better Than What We Have?
      What's a T Cell COVID Vaccine and Could It Be Better Than What We Have?
      All vaccines train the immune system to recognize and wage war against pathogens such as viruses and bacteria. However, ...
      Written By: Tara Fernandes
      1
      NOV 24, 2021
      Drug Discovery & Development
      A prescription digital therapeutic to treat alcohol use disorders
      A prescription digital therapeutic to treat alcohol use disorders
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      3
      NOV 23, 2021
      Health & Medicine
      No Short Term Effects of THC-positive Breast Milk
      No Short Term Effects of THC-positive Breast Milk
      A recent study found that THC does not have short-term negative effects on an early, premature baby’s health. Rese ...
      Written By: Kerry Charron
      1
      NOV 23, 2021
      Infographics
      The Health Benefits of Cannabis
      The Health Benefits of Cannabis
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      NOV 22, 2021
      Health & Medicine
      Important Considerations in the Humanization of Antibodies
      Important Considerations in the Humanization of Antibodies
      In therapeutic applications, monoclonal antibodies (mAbs) provide highly precise targeting of pathological cells and red ...
      Sponsored By: Cyagen Le
      1
      NOV 22, 2021
      Cell & Molecular Biology
      Understanding an Unusual Receptor That's Linked to Depression
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      2
      NOV 22, 2021
      Health & Medicine
      Can Nanotechnology Prevent Corneal Graft Rejection?
      Can Nanotechnology Prevent Corneal Graft Rejection?
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      2
      NOV 22, 2021
      Microbiology
      Researchers Solve the Structure of the HIV Capsid, May Be a New Drug Target
      Researchers Solve the Structure of the HIV Capsid, May Be a New Drug Target
      Though treatments are available, there is no cure or vaccine from HIV, which impacts about 38 million people worldwide. ...
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      1
      NOV 22, 2021
      Cancer
      A New Treatment Option for Patients with Cancer in the Eye
      A New Treatment Option for Patients with Cancer in the Eye
      Uveal melanoma (UM) is a rare malignancy characterized by the formation of cancer cells in the tissues of the eye. UM be ...
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      3
      NOV 20, 2021
      Neuroscience
      Fear balance - the brain and body communicate to maintain fear within an adaptive range
      Fear balance - the brain and body communicate to maintain fear within an adaptive range
      We have all experienced the emotion of fear. Although what one individual might fear (e.g. rollercoasters or snakes), mi ...
      Written By: J. Bryce Ortiz
      2
      NOV 19, 2021
      Cannabis Sciences
      Topical CBD Reverses UV-Induced Changes in Skin
      Topical CBD Reverses UV-Induced Changes in Skin
      Results from a new study published in Nature’s Scientific Reports suggest that topical application of cannabidiol ...
      Written By: Nadine Husami
      2
      NOV 19, 2021
      Neuroscience
      Exercise Fights Inflammation by Increasing Body's Own Cannabis Production
      Exercise Fights Inflammation by Increasing Body's Own Cannabis Production
      Exercise increases the body’s production of endocannabinoids, which in turn reduces inflammation and pain in condi ...
      Written By: Annie Lennon
      2
      NOV 19, 2021
      Genetics & Genomics
      Transcriptomics Method Can Reveal Genes Behind Venom Production
      Transcriptomics Method Can Reveal Genes Behind Venom Production
      Some of our best medications have come from nature. For years, researchers have been studying the properties of differen ...
      Written By: Carmen Leitch
      1
      NOV 19, 2021
      Health & Medicine
      Increase in Cannabis Use Disorder in Prenatal Hospitalizations
      Increase in Cannabis Use Disorder in Prenatal Hospitalizations
      A recent study by Columbia University and Weill Cornell Medicine researchers found that cannabis use disorder (CUD) in p ...
      Written By: Kerry Charron
      1
      NOV 18, 2021
      Cannabis Sciences
      Could Cannabis-Based Compounds Be the Next New Class of Antibiotics?
      Could Cannabis-Based Compounds Be the Next New Class of Antibiotics?
      According to the Centers for Disease Prevention and Control (CDC), antibiotic-resistant bacterial or fungal strains infe ...
      Written By: Nadine Husami
      1
    DEC 01, 2021
    Drug Discovery & Development
    Researchers develop a novel drug that can combat diabetic tissue damage
    Researchers develop a novel drug that can combat diabetic tissue damage
    Diabetes is a common disease that occurs when high levels of blood sugar start to silently damage bodily tissue and orga ...
    Written By: J. Bryce Ortiz
    1
    NOV 30, 2021
    Cannabis Sciences
    To Trust or Not to Trust the Process: Bioreactive Chemical Variation in Cannabis Extracts Based on Extraction Method
    To Trust or Not to Trust the Process: Bioreactive Chemical Variation in Cannabis Extracts Based on Extraction Method
    With cannabis legislation becoming increasingly less restrictive over the past 20 years, consumers have found themselves ...
    Written By: Nadine Husami
    1
    NOV 30, 2021
    Cannabis Sciences
    Terpene-Mediated Modulation of Cannabinoid Activity
    Terpene-Mediated Modulation of Cannabinoid Activity
    A popular theory – the “entourage effect” – has been gaining traction amongst the cannabis scien ...
    Written By: Nadine Husami
    1
    NOV 30, 2021
    Immunology
    Sweet Escape: A Sugar Molecule Helps HIV Remain Incognito
    Sweet Escape: A Sugar Molecule Helps HIV Remain Incognito
    HIV is a master of disguise. Once the virus enters the body, it has a number of sophisticated mechanisms through which i ...
    Written By: Tara Fernandes
    1
    NOV 30, 2021
    Drug Discovery & Development
    Enabling new levels of quantification with the SCIEX 7500 system - powered by SCIEX OS Software
    Enabling new levels of quantification with the SCIEX 7500 system - powered by SCIEX OS Software
    Sensitivity is a fundamental performance characteristic of a mass spectrometer The SCIEX 7500 system is enabling new lev ...
    Written By: SCIEX Le
    1
     
     
  • NOV 29, 2021
    Genetics & Genomics
    A CRISPR-Based Technique to Make New Antibiotics
    A CRISPR-Based Technique to Make New Antibiotics
    There are many bacterial organisms, and they can live cooperatively, or they can battle one another. They are also capab ...
    Written By: Carmen Leitch
    4
    NOV 29, 2021
    Cancer
    An Amino Acid Can Improve Radiation Therapy for Metastatic Brain Cancer
    An Amino Acid Can Improve Radiation Therapy for Metastatic Brain Cancer
    There are 20 different amino acids that the human body uses to generate proteins.  Amino acids form chains called p ...
    Written By: Katie Kokolus
    3
    NOV 25, 2021
    Microbiology
    How Microbes Use Copper to Make an Antibiotic
    How Microbes Use Copper to Make an Antibiotic
    Copper is known to have antibacterial properties, and though it's an important chemical for many organisms, it can b ...
    Written By: Carmen Leitch
    2
    NOV 25, 2021
    Immunology
    Battling Bacterial Pneumonia, No Antibiotics Required
    Battling Bacterial Pneumonia, No Antibiotics Required
    Instead of flooding the body with antibiotics, what if we could program cells to fight off pathogens more effectively? T ...
    Written By: Tara Fernandes
    1
    NOV 25, 2021
    Immunology
    What's a T Cell COVID Vaccine and Could It Be Better Than What We Have?
    What's a T Cell COVID Vaccine and Could It Be Better Than What We Have?
    All vaccines train the immune system to recognize and wage war against pathogens such as viruses and bacteria. However, ...
    Written By: Tara Fernandes
    1
     
     
  • NOV 24, 2021
    Drug Discovery & Development
    A prescription digital therapeutic to treat alcohol use disorders
    A prescription digital therapeutic to treat alcohol use disorders
    Can a software application be used treat alcohol use disorders? The medical technology company Pear Therapeutics is ...
    Written By: J. Bryce Ortiz
    3
    NOV 23, 2021
    Health & Medicine
    No Short Term Effects of THC-positive Breast Milk
    No Short Term Effects of THC-positive Breast Milk
    A recent study found that THC does not have short-term negative effects on an early, premature baby’s health. Rese ...
    Written By: Kerry Charron
    1
    NOV 23, 2021
    Infographics
    The Health Benefits of Cannabis
    The Health Benefits of Cannabis
    Legislation is opening more and more doors for cannabis- causing an explosion in both research and marketing campaigns f ...
    Written By: Annie Lennon
    3 1
    NOV 22, 2021
    Health & Medicine
    Important Considerations in the Humanization of Antibodies
    Important Considerations in the Humanization of Antibodies
    In therapeutic applications, monoclonal antibodies (mAbs) provide highly precise targeting of pathological cells and red ...
    Sponsored By: Cyagen Le
    1
    NOV 22, 2021
    Cell & Molecular Biology
    Understanding an Unusual Receptor That's Linked to Depression
    Understanding an Unusual Receptor That's Linked to Depression
    Clinical depression is estimated to impact over 264 million people worldwide in any given year, but it's difficult to tr ...
    Written By: Carmen Leitch
    2
     
     
  • NOV 22, 2021
    Health & Medicine
    Can Nanotechnology Prevent Corneal Graft Rejection?
    Can Nanotechnology Prevent Corneal Graft Rejection?
    The cornea is among the essential anatomic features of the eye, responsible for most of the eye’s focusing ability ...
    Written By: Christopher DiMaio
    2
    NOV 22, 2021
    Microbiology
    Researchers Solve the Structure of the HIV Capsid, May Be a New Drug Target
    Researchers Solve the Structure of the HIV Capsid, May Be a New Drug Target
    Though treatments are available, there is no cure or vaccine from HIV, which impacts about 38 million people worldwide. ...
    Written By: Carmen Leitch
    1
    NOV 22, 2021
    Cancer
    A New Treatment Option for Patients with Cancer in the Eye
    A New Treatment Option for Patients with Cancer in the Eye
    Uveal melanoma (UM) is a rare malignancy characterized by the formation of cancer cells in the tissues of the eye. UM be ...
    Written By: Katie Kokolus
    3
    NOV 20, 2021
    Neuroscience
    Fear balance - the brain and body communicate to maintain fear within an adaptive range
    Fear balance - the brain and body communicate to maintain fear within an adaptive range
    We have all experienced the emotion of fear. Although what one individual might fear (e.g. rollercoasters or snakes), mi ...
    Written By: J. Bryce Ortiz
    2
    NOV 19, 2021
    Cannabis Sciences
    Topical CBD Reverses UV-Induced Changes in Skin
    Topical CBD Reverses UV-Induced Changes in Skin
    Results from a new study published in Nature’s Scientific Reports suggest that topical application of cannabidiol ...
    Written By: Nadine Husami
    2
     
     
  • NOV 19, 2021
    Neuroscience
    Exercise Fights Inflammation by Increasing Body's Own Cannabis Production
    Exercise Fights Inflammation by Increasing Body's Own Cannabis Production
    Exercise increases the body’s production of endocannabinoids, which in turn reduces inflammation and pain in condi ...
    Written By: Annie Lennon
    2
    NOV 19, 2021
    Genetics & Genomics
    Transcriptomics Method Can Reveal Genes Behind Venom Production
    Transcriptomics Method Can Reveal Genes Behind Venom Production
    Some of our best medications have come from nature. For years, researchers have been studying the properties of differen ...
    Written By: Carmen Leitch
    1
    NOV 19, 2021
    Health & Medicine
    Increase in Cannabis Use Disorder in Prenatal Hospitalizations
    Increase in Cannabis Use Disorder in Prenatal Hospitalizations
    A recent study by Columbia University and Weill Cornell Medicine researchers found that cannabis use disorder (CUD) in p ...
    Written By: Kerry Charron
    1
    NOV 18, 2021
    Cannabis Sciences
    Could Cannabis-Based Compounds Be the Next New Class of Antibiotics?
    Could Cannabis-Based Compounds Be the Next New Class of Antibiotics?
    According to the Centers for Disease Prevention and Control (CDC), antibiotic-resistant bacterial or fungal strains infe ...
    Written By: Nadine Husami
    1
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