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    Drug Discovery

    Drug Discovery: drug discovery is the process by which new candidate medications are discovered. Historically, drugs were discovered through identifying the active ingredient from traditional remedies or by serendipitous discovery. Modern drug discovery involves the identification of screening hits, medicinal chemistry and optimization of those hits to increase the affinity, selectivity (to reduce the potential of side effects), efficacy/potency, metabolic stability (to increase the half-life), and oral bioavailability.

    Trending News

    • OCT 11, 2020
      Drug Discovery & Development
      Treating Connective Tissue Disorders
      Treating Connective Tissue Disorders
      Collaborative research efforts are geared to improving disease that affects connective tissues via innovative drug deliv ...
      Written By: Nouran Amin
      2
      OCT 10, 2020
      Drug Discovery & Development
      Fishnet of Nanoparticles Traps Drug Molecules
      Fishnet of Nanoparticles Traps Drug Molecules
      ‘Fishnet’ Nanoparticles Traps Drug Molecules A team at Northwestern University have casted a net of nanopart ...
      Written By: Nouran Amin
      1
      OCT 09, 2020
      Technology
      Deep Learning Advances Drug Design
      Deep Learning Advances Drug Design
      Computational data is advancing all areas of medicine and pharmaceutical drug development is certainly no exception. &nb ...
      Written By: Nouran Amin
      1
      OCT 07, 2020
      Technology
      Millimeter-Precision Drug Delivery
      Millimeter-Precision Drug Delivery
      It is almost impossible to deliver targeted drug therapy via the bloodstream without reaching the entire brain and body ...
      Written By: Nouran Amin
      1
      OCT 07, 2020
      Cancer
      Delivering Cancer Drugs to Osteosarcoma with Nanoparticles
      Delivering Cancer Drugs to Osteosarcoma with Nanoparticles
      Over the years, cancer researchers have struggled not just with drug and diagnostic design, but with drug delivery. The ...
      Written By: Jasper Cantrell
      1
      OCT 06, 2020
      Drug Discovery & Development
      Drug For A Severe E. Coli Infection
      Drug For A Severe E. Coli Infection
      Escherichia coli, known as E. coli, is a popular bacterium associated with food poisoning and depending on the strain ca ...
      Written By: Nouran Amin
      1
      OCT 06, 2020
      Technology
      Web Resources Provide Insights Into COVID-19 Research
      Web Resources Provide Insights Into COVID-19 Research
      Web resources are now helping researchers globally to answer critical questions about the COVID-19 pandemic. These resou ...
      Written By: Nouran Amin
      1
      OCT 06, 2020
      Cardiology
      A New Heart Drug Taken from a Yellow Dye
      A New Heart Drug Taken from a Yellow Dye
      Cardiovascular disease is an ever-present issue in the modern world.  One of the most unfortunate cardiovascular ev ...
      Written By: Jasper Cantrell
      1
      OCT 06, 2020
      Cannabis Sciences
      Cannabis Use May Reduce Cancer Risk by 10%
      Cannabis Use May Reduce Cancer Risk by 10%
      A recent meta-analysis of 34 studies found that cannabis use may decrease one’s risk of developing certain kinds o ...
      Written By: Annie Lennon
      1
      OCT 06, 2020
      Drug Discovery & Development
      New Immunotherapy Drug Effective Against Lung Cancer
      New Immunotherapy Drug Effective Against Lung Cancer
      A new study has confirmed that Tecentriq, an immunotherapy drug, improves survival rates among those with newly diagnose ...
      Written By: Annie Lennon
      1
      OCT 05, 2020
      Drug Discovery & Development
      Fecal Transplants Could Restore Cognitive Function in the Elderly
      Fecal Transplants Could Restore Cognitive Function in the Elderly
      An international team of researchers has found that fecal transplants could one day be used to restore cognitive functio ...
      Written By: Annie Lennon
      2
      OCT 03, 2020
      Drug Discovery & Development
      Treating Gut-Leakiness
      Treating Gut-Leakiness
      A drug called tofacitinib, also called Xeljanz , was found to treat permeability defects in the intestines. Tofacitinib ...
      Written By: Nouran Amin
      1
      OCT 03, 2020
      Cannabis Sciences
      Cannabis Compound Prevents Colon Cancer in Mice
      Cannabis Compound Prevents Colon Cancer in Mice
      Second only to skin cancer, colon cancer is the most common cancer diagnosed in both men and women in the US. Now, resea ...
      Written By: Annie Lennon
      1
      OCT 02, 2020
      Immunology
      Stop the Clot: A New Antibody Treatment for Thrombosis
      Stop the Clot: A New Antibody Treatment for Thrombosis
      Blood clotting helps stem the bleeding from a wound, suppressing blood loss and stopping pathogenic microorganisms from ...
      Written By: Tara Fernandes
      1
      OCT 01, 2020
      Drug Discovery & Development
      Antidepressants Treats Lazy Eye
      Antidepressants Treats Lazy Eye
      A study published in Current Biology revealed how a therapeutic used as an antidepressant and for managing pain could tr ...
      Written By: Nouran Amin
      1
      OCT 01, 2020
      Cancer
      Understanding in vivo Metabolomics: C13 Isotope Studies
      Understanding in vivo Metabolomics: C13 Isotope Studies
      One key to understanding cancer metabolomics lies in the ability to accurately replicate the natural environment of the ...
      Sponsored By: Human Metabolome Technologies
      2
      OCT 01, 2020
      Drug Discovery & Development
      HPV Vaccine Protects Against Cervical Cancer, Large Study Finds
      HPV Vaccine Protects Against Cervical Cancer, Large Study Finds
      It has been known for some time that the HPV vaccine protects against human papillomavirus infection, genital warts, and ...
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      2
      OCT 01, 2020
      Immunology
      Immune Cells and MS: The Good, the Bad, and the Maybe
      Immune Cells and MS: The Good, the Bad, and the Maybe
      Much like electrical wires that are encased in plastic insulating sheaths, nerve cells also are also surrounded by a sim ...
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      3 1
      SEP 30, 2020
      Cancer
      Chemokines Could be the Key in Controlling Glioma Stem Cells
      Chemokines Could be the Key in Controlling Glioma Stem Cells
      The transformation of a healthy cell into a cancerous one often comes with a slew of cellular signaling changes.  T ...
      Written By: Jasper Cantrell
      1
      SEP 29, 2020
      Cardiology
      Improving Acute Myocardial Ischemia Treatment with Nitro Fatty Acids
      Improving Acute Myocardial Ischemia Treatment with Nitro Fatty Acids
      Acute myocardial ischemia occurs when blood flow is restricted in the heart. This usually leads to cardiovascular issues ...
      Written By: Jasper Cantrell
      1
      SEP 29, 2020
      Drug Discovery & Development
      Cycling Molecules into Drug Candidates
      Cycling Molecules into Drug Candidates
      Statistics show that just 1 in 5,000 drug candidates ever makes it from the lab to the pharmacy. In a process that can t ...
      Sponsored By: Charles River
      1 2
      SEP 27, 2020
      Cannabis Sciences
      THC Shows Promise in Treating Severe Cases of COVID-19
      THC Shows Promise in Treating Severe Cases of COVID-19
      Over the last few months, various headlines have emerged suggesting the potential for cannabinoids, and in particular, c ...
      Written By: Annie Lennon
      2
      SEP 27, 2020
      Cell & Molecular Biology
      How Spiders May Open a Path to IBS Treatment
      How Spiders May Open a Path to IBS Treatment
      Irritable bowel syndrome (IBS) is term that describes a gut disorder that causes abdominal pain, cramping, diarrhea or c ...
      Written By: Carmen Leitch
      1
      SEP 25, 2020
      Cell & Molecular Biology
      Researchers Take Organoids a Step Further
      Researchers Take Organoids a Step Further
      The human body is made of many different kinds of cells, which can often be cultured in a lab and studied. However, thos ...
      Written By: Carmen Leitch
      1
    OCT 11, 2020
    Drug Discovery & Development
    Treating Connective Tissue Disorders
    Treating Connective Tissue Disorders
    Collaborative research efforts are geared to improving disease that affects connective tissues via innovative drug deliv ...
    Written By: Nouran Amin
    2
    OCT 10, 2020
    Drug Discovery & Development
    Fishnet of Nanoparticles Traps Drug Molecules
    Fishnet of Nanoparticles Traps Drug Molecules
    ‘Fishnet’ Nanoparticles Traps Drug Molecules A team at Northwestern University have casted a net of nanopart ...
    Written By: Nouran Amin
    1
    OCT 09, 2020
    Technology
    Deep Learning Advances Drug Design
    Deep Learning Advances Drug Design
    Computational data is advancing all areas of medicine and pharmaceutical drug development is certainly no exception. &nb ...
    Written By: Nouran Amin
    1
    OCT 07, 2020
    Technology
    Millimeter-Precision Drug Delivery
    Millimeter-Precision Drug Delivery
    It is almost impossible to deliver targeted drug therapy via the bloodstream without reaching the entire brain and body ...
    Written By: Nouran Amin
    1
    OCT 07, 2020
    Cancer
    Delivering Cancer Drugs to Osteosarcoma with Nanoparticles
    Delivering Cancer Drugs to Osteosarcoma with Nanoparticles
    Over the years, cancer researchers have struggled not just with drug and diagnostic design, but with drug delivery. The ...
    Written By: Jasper Cantrell
    1
     
     
  • OCT 06, 2020
    Drug Discovery & Development
    Drug For A Severe E. Coli Infection
    Drug For A Severe E. Coli Infection
    Escherichia coli, known as E. coli, is a popular bacterium associated with food poisoning and depending on the strain ca ...
    Written By: Nouran Amin
    1
    OCT 06, 2020
    Technology
    Web Resources Provide Insights Into COVID-19 Research
    Web Resources Provide Insights Into COVID-19 Research
    Web resources are now helping researchers globally to answer critical questions about the COVID-19 pandemic. These resou ...
    Written By: Nouran Amin
    1
    OCT 06, 2020
    Cardiology
    A New Heart Drug Taken from a Yellow Dye
    A New Heart Drug Taken from a Yellow Dye
    Cardiovascular disease is an ever-present issue in the modern world.  One of the most unfortunate cardiovascular ev ...
    Written By: Jasper Cantrell
    1
    OCT 06, 2020
    Cannabis Sciences
    Cannabis Use May Reduce Cancer Risk by 10%
    Cannabis Use May Reduce Cancer Risk by 10%
    A recent meta-analysis of 34 studies found that cannabis use may decrease one’s risk of developing certain kinds o ...
    Written By: Annie Lennon
    1
    OCT 06, 2020
    Drug Discovery & Development
    New Immunotherapy Drug Effective Against Lung Cancer
    New Immunotherapy Drug Effective Against Lung Cancer
    A new study has confirmed that Tecentriq, an immunotherapy drug, improves survival rates among those with newly diagnose ...
    Written By: Annie Lennon
    1
     
     
  • OCT 05, 2020
    Drug Discovery & Development
    Fecal Transplants Could Restore Cognitive Function in the Elderly
    Fecal Transplants Could Restore Cognitive Function in the Elderly
    An international team of researchers has found that fecal transplants could one day be used to restore cognitive functio ...
    Written By: Annie Lennon
    2
    OCT 03, 2020
    Drug Discovery & Development
    Treating Gut-Leakiness
    Treating Gut-Leakiness
    A drug called tofacitinib, also called Xeljanz , was found to treat permeability defects in the intestines. Tofacitinib ...
    Written By: Nouran Amin
    1
    OCT 03, 2020
    Cannabis Sciences
    Cannabis Compound Prevents Colon Cancer in Mice
    Cannabis Compound Prevents Colon Cancer in Mice
    Second only to skin cancer, colon cancer is the most common cancer diagnosed in both men and women in the US. Now, resea ...
    Written By: Annie Lennon
    1
    OCT 02, 2020
    Immunology
    Stop the Clot: A New Antibody Treatment for Thrombosis
    Stop the Clot: A New Antibody Treatment for Thrombosis
    Blood clotting helps stem the bleeding from a wound, suppressing blood loss and stopping pathogenic microorganisms from ...
    Written By: Tara Fernandes
    1
    OCT 01, 2020
    Drug Discovery & Development
    Antidepressants Treats Lazy Eye
    Antidepressants Treats Lazy Eye
    A study published in Current Biology revealed how a therapeutic used as an antidepressant and for managing pain could tr ...
    Written By: Nouran Amin
    1
     
     
  • OCT 01, 2020
    Cancer
    Understanding in vivo Metabolomics: C13 Isotope Studies
    Understanding in vivo Metabolomics: C13 Isotope Studies
    One key to understanding cancer metabolomics lies in the ability to accurately replicate the natural environment of the ...
    Sponsored By: Human Metabolome Technologies
    2
    OCT 01, 2020
    Drug Discovery & Development
    HPV Vaccine Protects Against Cervical Cancer, Large Study Finds
    HPV Vaccine Protects Against Cervical Cancer, Large Study Finds
    It has been known for some time that the HPV vaccine protects against human papillomavirus infection, genital warts, and ...
    Written By: Annie Lennon
    2
    OCT 01, 2020
    Immunology
    Immune Cells and MS: The Good, the Bad, and the Maybe
    Immune Cells and MS: The Good, the Bad, and the Maybe
    Much like electrical wires that are encased in plastic insulating sheaths, nerve cells also are also surrounded by a sim ...
    Written By: Tara Fernandes
    3 1
    SEP 30, 2020
    Cancer
    Chemokines Could be the Key in Controlling Glioma Stem Cells
    Chemokines Could be the Key in Controlling Glioma Stem Cells
    The transformation of a healthy cell into a cancerous one often comes with a slew of cellular signaling changes.  T ...
    Written By: Jasper Cantrell
    1
    SEP 29, 2020
    Cardiology
    Improving Acute Myocardial Ischemia Treatment with Nitro Fatty Acids
    Improving Acute Myocardial Ischemia Treatment with Nitro Fatty Acids
    Acute myocardial ischemia occurs when blood flow is restricted in the heart. This usually leads to cardiovascular issues ...
    Written By: Jasper Cantrell
    1
     
     
  • SEP 29, 2020
    Drug Discovery & Development
    Cycling Molecules into Drug Candidates
    Cycling Molecules into Drug Candidates
    Statistics show that just 1 in 5,000 drug candidates ever makes it from the lab to the pharmacy. In a process that can t ...
    Sponsored By: Charles River
    1 2
    SEP 27, 2020
    Cannabis Sciences
    THC Shows Promise in Treating Severe Cases of COVID-19
    THC Shows Promise in Treating Severe Cases of COVID-19
    Over the last few months, various headlines have emerged suggesting the potential for cannabinoids, and in particular, c ...
    Written By: Annie Lennon
    2
    SEP 27, 2020
    Cell & Molecular Biology
    How Spiders May Open a Path to IBS Treatment
    How Spiders May Open a Path to IBS Treatment
    Irritable bowel syndrome (IBS) is term that describes a gut disorder that causes abdominal pain, cramping, diarrhea or c ...
    Written By: Carmen Leitch
    1
    SEP 25, 2020
    Cell & Molecular Biology
    Researchers Take Organoids a Step Further
    Researchers Take Organoids a Step Further
    The human body is made of many different kinds of cells, which can often be cultured in a lab and studied. However, thos ...
    Written By: Carmen Leitch
    1
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