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    Engineering T cells

    Engineering T cells is a broad description of techniques used to modify a T cells obtained from a patient or healthy donor. T cells are a subset of immune cells responsible for targeting and killing tumor cells. Once harvested from a patient or donor, the T cells can be engineered in a laboratory making them better capable of killing a specific tumor. Examples of adoptive cell therapies using engineered T cells are T cell receptor (TCR)-engineered T cells and chimeric antigen receptor (CAR) T cells.

    Trending News

    • JAN 04, 2021
      Cell & Molecular Biology
      Good Results From Trial of CAR T Cell Therapy for Non-Hodgkin Lymphoma
      Good Results From Trial of CAR T Cell Therapy for Non-Hodgkin Lymphoma
      Researchers have reported positive results from a phase 2 clinical trial of a CAR T cell therapy called axicabtagene cil ...
      Written By: Carmen Leitch
      1
      DEC 30, 2020
      Cell & Molecular Biology
      Measuring Electrical Differences Inside of Live Cells
      Measuring Electrical Differences Inside of Live Cells
      Electricity is a key aspect of life, and is required for organisms to move and communicate. The movement of tiny charged ...
      Written By: Carmen Leitch
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      DEC 29, 2020
      Microbiology
      How CRISPR Can Help Create a Vaccine for a Common Parasite
      How CRISPR Can Help Create a Vaccine for a Common Parasite
      The parasite Toxoplasma gondii is thought to infect a third of the people on the planet as well as a wide range of other ...
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      DEC 29, 2020
      Immunology
      Cancer-Killing Viruses Enter in Stealth Mode, Penetrate Immune Barrier
      Cancer-Killing Viruses Enter in Stealth Mode, Penetrate Immune Barrier
      Viruses that when administered to patients preferentially attack and kill cancer cells, leaving normal tissues unscathed ...
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      DEC 27, 2020
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      Written By: Carmen Leitch
      4
      DEC 20, 2020
      Microbiology
      How Do mRNA Vaccines Work?
      How Do mRNA Vaccines Work?
      Scientist Katalin Karikó studied mRNA vaccines for years. She spent years getting grant rejections, but has now helped c ...
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      4
      DEC 16, 2020
      Chemistry & Physics
      Applying photocycloaddition to modify graphene
      Applying photocycloaddition to modify graphene
      Research published recently in the journal Nature Chemistry reports on the development of a new technique that uses ...
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      DEC 11, 2020
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      When Microbes Battle for Survival, the Weakest Can Win
      When Microbes Battle for Survival, the Weakest Can Win
      Our world is filled with different types of bacteria, and they have to coexist with one another. They have to compete fo ...
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      1
      DEC 09, 2020
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      Weed-Killer Causes Epigenetic Changes That May Predict Disease Risk
      Weed-Killer Causes Epigenetic Changes That May Predict Disease Risk
      Glyphosate is a common weed-killing chemical used in agriculture, and it may be best known as the active ingredient in R ...
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      1
      DEC 08, 2020
      Immunology
      Drug Targets Cold Tumors' Achilles Heel
      Drug Targets Cold Tumors' Achilles Heel
      Immunotherapies have emerged as a powerful treatment modality for cancer. They join chemotherapy, surgery, radiotherapy, ...
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      DEC 07, 2020
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      DEC 04, 2020
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      OTC Drug Found Safe for Multiple Myeloma
      Injecting the immune-boosting drug ‘teclistamab’ was found to be safe and effective in patients with relapse ...
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      NOV 29, 2020
      Cell & Molecular Biology
      Engineering 'Smart' Cells to Kill Cancer
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      Cancer researchers have long been searching for a way to target cancer cells while ignoring healthy cells. A team of sci ...
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      NOV 29, 2020
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      NOV 29, 2020
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      Gene Therapy for Eye Disorder May Have Other Applications
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      NOV 24, 2020
      Chemistry & Physics
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      How long does COVID-19 stay on surfaces?
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      NOV 23, 2020
      Cell & Molecular Biology
      Vibrations in Coronavirus Proteins Help Them Infect Cells
      Vibrations in Coronavirus Proteins Help Them Infect Cells
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      NOV 19, 2020
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      Parasitic Worms Help Unravel the Immune Mechanisms Underlying Chronic Disease
      Parasitic worms known as helminths have a complicated relationship with the immune systems of the hosts they invade. Ter ...
      Written By: Tara Fernandes
      2
      NOV 01, 2020
      Microbiology
      SARS-CoV-2 Disrupts the Blood Brain Barrier
      SARS-CoV-2 Disrupts the Blood Brain Barrier
      SARS-CoV-2, which causes COVID-19 has to get into cells to cause infection. It does so with a spike protein on its surfa ...
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      2
      OCT 29, 2020
      Genetics & Genomics
      Severe Genomic Damage in Human Embryos Treated With CRISPR
      Severe Genomic Damage in Human Embryos Treated With CRISPR
      The CRISPR-Cas9 genomic editing system holds great promise for treating genetic errors that cause human disease. But we ...
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      1
      OCT 24, 2020
      Immunology
      New CRISPR-Based Imaging Tool Is Going to Be HiUGE
      New CRISPR-Based Imaging Tool Is Going to Be HiUGE
      A team of researchers at Duke University have developed an imaging technology for tagging structures at a cellular level ...
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      1
      OCT 21, 2020
      Drug Discovery & Development
      Experimental Vaccine Shows Promise in Halting Alzheimer's
      Experimental Vaccine Shows Promise in Halting Alzheimer's
      In a preclinical study, researchers from the Univerity of South Florida have found that a vaccine that targets neurotoxi ...
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      OCT 21, 2020
      Cell & Molecular Biology
      Extracellular Vesicles Help Heart Cells Survive a Heart Attack
      Extracellular Vesicles Help Heart Cells Survive a Heart Attack
      During a heart attack, blood flow is blocked and cells lose oxygen and begin to die. Scientists are developing many new ...
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      OCT 19, 2020
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      Genetically Engineered Foods Could Alleviate Nutritional Deficiencies
      Genetically Engineered Foods Could Alleviate Nutritional Deficiencies
      There are over two billion people around the world that don't get the recommended levels of minerals and vitamins in ...
      Written By: Carmen Leitch
      1
    JAN 04, 2021
    Cell & Molecular Biology
    Good Results From Trial of CAR T Cell Therapy for Non-Hodgkin Lymphoma
    Good Results From Trial of CAR T Cell Therapy for Non-Hodgkin Lymphoma
    Researchers have reported positive results from a phase 2 clinical trial of a CAR T cell therapy called axicabtagene cil ...
    Written By: Carmen Leitch
    1
    DEC 30, 2020
    Cell & Molecular Biology
    Measuring Electrical Differences Inside of Live Cells
    Measuring Electrical Differences Inside of Live Cells
    Electricity is a key aspect of life, and is required for organisms to move and communicate. The movement of tiny charged ...
    Written By: Carmen Leitch
    1
    DEC 29, 2020
    Microbiology
    How CRISPR Can Help Create a Vaccine for a Common Parasite
    How CRISPR Can Help Create a Vaccine for a Common Parasite
    The parasite Toxoplasma gondii is thought to infect a third of the people on the planet as well as a wide range of other ...
    Written By: Carmen Leitch
    2
    DEC 29, 2020
    Immunology
    Cancer-Killing Viruses Enter in Stealth Mode, Penetrate Immune Barrier
    Cancer-Killing Viruses Enter in Stealth Mode, Penetrate Immune Barrier
    Viruses that when administered to patients preferentially attack and kill cancer cells, leaving normal tissues unscathed ...
    Written By: Tara Fernandes
    1
    DEC 27, 2020
    Genetics & Genomics
    Delivering DNA- & RNA-Based Therapies in a New Way
    Delivering DNA- & RNA-Based Therapies in a New Way
    Gene therapy holds tremendous promise for its potential to cure genetic diseases. We've also recently seen how critical ...
    Written By: Carmen Leitch
    4
     
     
  • DEC 20, 2020
    Microbiology
    How Do mRNA Vaccines Work?
    How Do mRNA Vaccines Work?
    Scientist Katalin Karikó studied mRNA vaccines for years. She spent years getting grant rejections, but has now helped c ...
    Written By: Carmen Leitch
    4
    DEC 16, 2020
    Chemistry & Physics
    Applying photocycloaddition to modify graphene
    Applying photocycloaddition to modify graphene
    Research published recently in the journal Nature Chemistry reports on the development of a new technique that uses ...
    Written By: Kathryn DeMuth Sullivan
    2
    DEC 11, 2020
    Microbiology
    When Microbes Battle for Survival, the Weakest Can Win
    When Microbes Battle for Survival, the Weakest Can Win
    Our world is filled with different types of bacteria, and they have to coexist with one another. They have to compete fo ...
    Written By: Carmen Leitch
    1
    DEC 09, 2020
    Genetics & Genomics
    Weed-Killer Causes Epigenetic Changes That May Predict Disease Risk
    Weed-Killer Causes Epigenetic Changes That May Predict Disease Risk
    Glyphosate is a common weed-killing chemical used in agriculture, and it may be best known as the active ingredient in R ...
    Written By: Carmen Leitch
    1
    DEC 08, 2020
    Immunology
    Drug Targets Cold Tumors' Achilles Heel
    Drug Targets Cold Tumors' Achilles Heel
    Immunotherapies have emerged as a powerful treatment modality for cancer. They join chemotherapy, surgery, radiotherapy, ...
    Written By: Tara Fernandes
    2
     
     
  • DEC 07, 2020
    Cell & Molecular Biology
    Cellular Structure Discovered Inside Peroxisomes
    Cellular Structure Discovered Inside Peroxisomes
    Rice University researcher Zachary Wright has discovered a previously unknown compartment inside cellular organelles cal ...
    Written By: Carmen Leitch
    1
    DEC 04, 2020
    Drug Discovery & Development
    OTC Drug Found Safe for Multiple Myeloma
    OTC Drug Found Safe for Multiple Myeloma
    Injecting the immune-boosting drug ‘teclistamab’ was found to be safe and effective in patients with relapse ...
    Written By: Nouran Amin
    1
    NOV 29, 2020
    Cell & Molecular Biology
    Engineering 'Smart' Cells to Kill Cancer
    Engineering 'Smart' Cells to Kill Cancer
    Cancer researchers have long been searching for a way to target cancer cells while ignoring healthy cells. A team of sci ...
    Written By: Carmen Leitch
    1
    NOV 29, 2020
    Microbiology
    Modeling the Evolution of Antibiotic Resistance
    Modeling the Evolution of Antibiotic Resistance
    Pathogenic bacteria are becoming increasingly resistant to standard antibiotics, for a variety of reasons. Scientists ar ...
    Written By: Carmen Leitch
    1
    NOV 29, 2020
    Genetics & Genomics
    Gene Therapy for Eye Disorder May Have Other Applications
    Gene Therapy for Eye Disorder May Have Other Applications
    In recent years, scientists have been able to develop gene therapies to treat some eye diseases. The eyes are uniquely q ...
    Written By: Carmen Leitch
    1
     
     
  • NOV 24, 2020
    Chemistry & Physics
    How long does COVID-19 stay on surfaces?
    How long does COVID-19 stay on surfaces?
    New research published today in Physics of Fluids explores the drying times of COVID-19 on different think liquid film s ...
    Written By: Kathryn DeMuth Sullivan
    1
    NOV 23, 2020
    Cell & Molecular Biology
    Vibrations in Coronavirus Proteins Help Them Infect Cells
    Vibrations in Coronavirus Proteins Help Them Infect Cells
    If a key isn't cut quite right, it might need a special jiggle to get it into a lock in the right way. Scientists have n ...
    Written By: Carmen Leitch
    1
    NOV 19, 2020
    Immunology
    Parasitic Worms Help Unravel the Immune Mechanisms Underlying Chronic Disease
    Parasitic Worms Help Unravel the Immune Mechanisms Underlying Chronic Disease
    Parasitic worms known as helminths have a complicated relationship with the immune systems of the hosts they invade. Ter ...
    Written By: Tara Fernandes
    2
    NOV 01, 2020
    Microbiology
    SARS-CoV-2 Disrupts the Blood Brain Barrier
    SARS-CoV-2 Disrupts the Blood Brain Barrier
    SARS-CoV-2, which causes COVID-19 has to get into cells to cause infection. It does so with a spike protein on its surfa ...
    Written By: Carmen Leitch
    2
    OCT 29, 2020
    Genetics & Genomics
    Severe Genomic Damage in Human Embryos Treated With CRISPR
    Severe Genomic Damage in Human Embryos Treated With CRISPR
    The CRISPR-Cas9 genomic editing system holds great promise for treating genetic errors that cause human disease. But we ...
    Written By: Carmen Leitch
    1
     
     
  • OCT 24, 2020
    Immunology
    New CRISPR-Based Imaging Tool Is Going to Be HiUGE
    New CRISPR-Based Imaging Tool Is Going to Be HiUGE
    A team of researchers at Duke University have developed an imaging technology for tagging structures at a cellular level ...
    Written By: Tara Fernandes
    1
    OCT 21, 2020
    Drug Discovery & Development
    Experimental Vaccine Shows Promise in Halting Alzheimer's
    Experimental Vaccine Shows Promise in Halting Alzheimer's
    In a preclinical study, researchers from the Univerity of South Florida have found that a vaccine that targets neurotoxi ...
    Written By: Annie Lennon
    1
    OCT 21, 2020
    Cell & Molecular Biology
    Extracellular Vesicles Help Heart Cells Survive a Heart Attack
    Extracellular Vesicles Help Heart Cells Survive a Heart Attack
    During a heart attack, blood flow is blocked and cells lose oxygen and begin to die. Scientists are developing many new ...
    Written By: Carmen Leitch
    1
    OCT 19, 2020
    Plants & Animals
    Genetically Engineered Foods Could Alleviate Nutritional Deficiencies
    Genetically Engineered Foods Could Alleviate Nutritional Deficiencies
    There are over two billion people around the world that don't get the recommended levels of minerals and vitamins in ...
    Written By: Carmen Leitch
    1
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