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    Fibrosis

    Fibrosis: is the formation of excess fibrous connective tissue in an organ or tissue in a reparative or reactive process. This can be a reactive, benign, or pathological state. In response to injury, this is called scarring, and if fibrosis arises from a single cell line, this is called a fibroma.

    Webinars

    • NOV 09, 2023 | 6:00 AM
      Using MERFISH to decode spatially regulated disease drivers in human heart and kidney disease
      Using MERFISH to decode spatially regulated disease drivers in...
      In this talk we will explore the application of Multiplexed Error-Robust Fluorescence in situ Hybridization (MERFISH) technology to decode spatially regulated disease drivers in human heart...
      Speaker: Christoph Kuppe, MD, MHBA
      Sponsored By: Vizgen
      8
      JUN 22, 2022 | 8:00 AM
      Effective application of targeted sequence analysis to propel the biopharmaceutic development continuum from pre-clinical research and biomarker discovery through manufacturing
      Effective application of targeted sequence analysis to propel...
      Biopharmaceutical discovery, development and manufacturing requires the use of genetic analysis across the development continuum. Sanger sequencing and fragment analysis by capillary electro...
      Speaker: Edgar Schreiber, PhD
      Sponsored By: Thermo Fisher Scientific
      9 2
      OCT 13, 2021 | 10:30 AM
      Spatial Transcriptomic Profiling of Severe COVID-19 Patients
      Spatial Transcriptomic Profiling of Severe COVID-19 Patients
      Severe SARS-CoV-2 infection often leads to development of acute respiratory distress syndrome (ARDS), with profound pulmonary patho-histological changes post-mortem. In this study, we utiliz...
      Speaker: Camilla Margaroli, PhD
      Presented at: Coronavirus Series
      Sponsored By: NanoString Technologies
      2
      APR 21, 2021 | 12:00 AM
      Flex Analysis: A Safe, Integrated and Flexible Approach to Non-Invasive Aneuploidy Analysis
      Flex Analysis: A Safe, Integrated and Flexible Approach to Non-Invasive...
      NGS Bioinformatics software has come of age. Our workflows need software solutions that don’t only carry out the correct calculations to give the correct results reliably and unambiguo...
      Speaker: Matthew C. Forman, PhD
      Presented at: Genetics Week Virtual Event Series 2021
      1
      APR 07, 2021 | 12:00 AM
      Anti-fibrotic materials for immunoprotected cell-based therapies
      Anti-fibrotic materials for immunoprotected cell-based therapies
      Cell encapsulation within semi-permeable devices represents a local immunoisolation strategy for cell-based therapies without the need for systemic immunosuppression. The encapsulation syste...
      Speaker: Dr. Matthew Bochenek, PhD
      Presented at: Bioprocessing Virtual Event Series 2021
      1
      SEP 09, 2020 | 10:00 AM
      Immunoprotective vs. immunopathogenic responses during fungal-associated allergic airway inflammation
      Immunoprotective vs. immunopathogenic responses during fungal-associated...
      Asthma is an increasing health concern affecting more than 25 million individuals in the United States and more than 300 million individuals worldwide. In some cases, sensitization or exposu...
      Speaker: Chad Steele, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      Sponsored By: Luminex - A DiaSorin Company
      1
      JUN 30, 2020 | 10:00 AM
      COVID-19 Serology Assays and Cell Therapy Strategies
      COVID-19 Serology Assays and Cell Therapy Strategies
      DATE: June 30, 2020 TIME: 10:00 am PDT, 1:00 pm EDT COVID-19 is a highly pathogenic disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We have assembled a panel...
      Speaker: Fatima Amanat , Dean Lee , Lior Raviv
      Sponsored By: Thermo Fisher Scientific/Gibco
      30 1
      JUN 17, 2020 | 3:00 PM
      Surgery as (Un)Usual: Development of Rodent Intracerebroventricular injection Capabilities During COVID-19
      Surgery as (Un)Usual: Development of Rodent Intracerebroventricular...
      Bringing a new research surgical model into production is always a challenging endeavor, and it has become much more challenging with the emergence of the Covid-19 pandemic. The virus’...
      Speaker: Matthew Flegal, BS, SRS
      Presented at: Coronavirus Series
      1
      JUN 04, 2020 | 2:00 PM
      Lipoma Preferred Partner (LPP) Regulates Breast Cancer Cell Migration and Invasion
      Lipoma Preferred Partner (LPP) Regulates Breast Cancer Cell Migration...
      In 2019, over 220,000 Canadians will be diagnosed with cancer and 82,000 will die of the disease. Approximately 90% of cancer related deaths are the result of metastatic disease. This is ind...
      Speaker: KEYNOTE: Claire Brown, PhD
      Presented at: Cell & Developmental Biology Virtual Meeting
      3
      JUN 03, 2020 | 12:00 AM
      Mining the molecular noise: fluorescence fluctuation image analysis of microscopy and super-resolution microscopy images reveals biomolecule interactions & transport maps in living cells
      Mining the molecular noise: fluorescence fluctuation image analysis...
      The transport properties of biomolecules in cells can reveal a great deal about the functional interactions regulating cells at the molecular level. Various biophysical methods have been dev...
      Speaker: Paul Wiseman, PhD
      Presented at: Cell & Developmental Biology Virtual Meeting
      2
      MAY 09, 2019 | 10:30 AM
      Somatic Gene Recombination in the Brain
      Somatic Gene Recombination in the Brain
      Speculations that some form DNA alteration might be utilized by the brain date to the 1960s [1] wherein hypotheses for genomic alterations of germline DNA were proposed for immunoglobulins an...
      Speaker: Jerold Chun, MD, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2019
      2
      FEB 14, 2019 | 12:00 PM
      Application of Micro-Physiological Systems for Respiratory Drug Discovery: Opportunities and Challenges
      Application of Micro-Physiological Systems for Respiratory Drug...
      The lung is a highly complex organ, comprised of more than 40 cell types that are responsible for various important functions, the lung’s complexity contributes to the subsequent challe...
      Speaker: David Rowlands, PhD
      Presented at: Laboratory Animal Sciences Virtual Event Series 2019
      1
      DEC 10, 2018 | 10:00 PM
      Better Data, Fewer Mice: micro-CT Imaging Breathes New Life into your Lung Research
      Better Data, Fewer Mice: micro-CT Imaging Breathes New Life into...
      DATE: December 11, 2018TIME: 06:00 PSTIt’s understood and accepted that animal disease models generally offer great value for pre-clinical research and efficient drug screeni...
      Speaker: Dr. Christian Dullin , Dr. Sasha (Alexandre) Belenkov , Dr. Francesca Ruscitti
      Sponsored By: Revvity
      4 1
      NOV 15, 2018 | 6:00 AM
      LIVE TRAINING: Pluripotent Stem Cell Picking
      LIVE TRAINING: Pluripotent Stem Cell Picking
      Picking stem cells, whether it be for clone selection or general line maintenance is an important and useful technique that for stem cell researchers should be comfortable with...
      Speaker: Carl Dargitz
      Presented at: 6th annual 24 Hours of Stem Cellsâ„¢ virtual event
      6
      NOV 14, 2018 | 3:00 PM
      Modeling Inflammation and Fibrosis in Humans with PSC-derived Steatohepatitis Liver Organoids
      Modeling Inflammation and Fibrosis in Humans with PSC-derived...
      Neuronal migration defects, including pachygyria, are among the most severe developmental brain defects in humans. Using human genetics approaches, we recently identified bi-allelic truncatin...
      Speaker: Takanori Takebe
      Presented at: 6th annual 24 Hours of Stem Cellsâ„¢ virtual event
      8
      SEP 13, 2018 | 6:00 AM
      The Hurricane Microbiome Project: Environmental Exposures and Population Health
      The Hurricane Microbiome Project: Environmental Exposures and...
      The Alkek Center for Metagenomics and Microbiome Research (CMMR) at Baylor College of Medicine is pursuing numerous research and development efforts in the study of how the microbiome impacts...
      Speaker: Joseph Petrosino, PhD
      Presented at: Microbiology & Immunology Virtual Event Series 2018
      1
      SEP 12, 2018 | 12:00 PM
      Antimicrobial Resistance Identification, Strain Typing, and Assay Design with CLC Genomics Workbench
      Antimicrobial Resistance Identification, Strain Typing, and Assay...
      Whole genome sequencing of bacterial isolates via next-generation sequencing is becoming a standard approach for clinical microbiology and bio-surveillance labs seeking to conduct outbreak in...
      Speaker: Winnie Ridderberg, PhD
      Presented at: Microbiology & Immunology Virtual Event Series 2018
      Sponsored By: QIAGEN
      3
      JUN 26, 2018 | 9:00 AM
      Automated In Vivo Efficacy Assessment in Preclinical Lung Disease Models
      Automated In Vivo Efficacy Assessment in Preclinical Lung Disease...
      Treatments for respiratory diseases represent an enormous, unmet medical need with limited therapies currently approved for use. Despite many compounds demonstrating beneficial effects in ani...
      Speaker: Laura Schaevitz, PhD
      Sponsored By: Vium
      6
      JUN 01, 2018 | 12:00 AM
      Embryonic Stem (ES) Cell FBS Qualified
      Embryonic Stem (ES) Cell FBS Qualified
      Thermo Fisher Scientific has developed an advanced assay to qualify FBS for use with ESCs.  This assay is designed to sustain undifferentiated ES cells while maintaining karyotype integr...
      Speaker: Carl Dargitz
      Presented at: 6th annual 24 Hours of Stem Cellsâ„¢ virtual event
      1
      MAY 09, 2018 | 10:30 AM
      The microRNA Regulatory Landscape of MSC-Derived Exosomes: A Systems View
      The microRNA Regulatory Landscape of MSC-Derived Exosomes: A Systems...
      Mesenchymal stem cell (MSC)-derived exosomes mediate tissue regeneration in a variety of diseases including ischemic heart injury, liver fibrosis, and cerebrovascular disease. Despite an incr...
      Speaker: Juliane Nguyen, PharmD, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2018
      Sponsored By: NanoString Technologies
      3
      APR 12, 2018 | 9:00 AM
      Metabolites, Germs and People: Eavesdropping on Human Microbial Communities
      Metabolites, Germs and People: Eavesdropping on Human Microbial...
      The Whiteson lab uses culture-independent metagenomics, metabolomics, and ecological statistics along with hypothesis driven, reductionist microbiology to answer questions about how bacteria...
      Speaker: Katrine Whiteson, PhD
      Presented at: Molecular Diagnostics Virtual Event Series 2018
      1
      FEB 22, 2018 | 1:30 PM
      Recent Trends in GPCR Drug Discovery: Novel Targets, New Disease Indications, and an Upsurge in Biologics
      Recent Trends in GPCR Drug Discovery: Novel Targets, New Disease...
      GPCRs constitute the largest receptor family in the human genome. Over the years they have proven themselves to be druggable targets accounting for about 1/3 of all drugs on the market today....
      Speaker: Annette Gilchrist, PhD
      Presented at: Drug Discovery Virtual Event Series 2018
      1
      SEP 13, 2017 | 12:00 PM
      High Resolution Outbreak Tracing and Resistance Detection using Whole Genome Sequencing in the case of a Mycobacterium tuberculosis Outbreak
      High Resolution Outbreak Tracing and Resistance Detection using...
      Background: In March 2014, a molecular cluster of five multidrug resistant Mycobacterium tuberculosis was detected by the Austrian National Reference Laboratory. An investigation was initiate...
      Speaker: Winnie Ridderberg, PhD
      Presented at: Microbiology & Immunology Virtual Event Series 2017
      1
      JUN 14, 2017 | 6:00 AM
      WEBINAR: Accelerated Data Workflows for Biomarker Discovery in Metabolomics: Clinical Research Applications in Cystic Fibrosis Research
      WEBINAR: Accelerated Data Workflows for Biomarker Discovery in...
      DATE: June 14, 2017TIME: 6:00am PT, 9:00am ET, 3:00pm CETComprehensive metabolite profiling (i.e., metabolomics) offers a holistic approach for understanding the phenotype of an organis...
      Speaker: Philip Britz-McKibbin
      Sponsored By: Agilent
      4
    NOV 09, 2023 | 6:00 AM
    Using MERFISH to decode spatially regulated disease drivers in human heart and kidney disease
    Using MERFISH to decode spatially regulated disease drivers in...
    In this talk we will explore the application of Multiplexed Error-Robust Fluorescence in situ Hybridization (MERFISH) technology to decode spatially regulated disease drivers in human heart...
    Speaker: Christoph Kuppe, MD, MHBA
    Sponsored By: Vizgen
    8
    JUN 22, 2022 | 8:00 AM
    Effective application of targeted sequence analysis to propel the biopharmaceutic development continuum from pre-clinical research and biomarker discovery through manufacturing
    Effective application of targeted sequence analysis to propel...
    Biopharmaceutical discovery, development and manufacturing requires the use of genetic analysis across the development continuum. Sanger sequencing and fragment analysis by capillary electro...
    Speaker: Edgar Schreiber, PhD
    Sponsored By: Thermo Fisher Scientific
    9 2
    OCT 13, 2021 | 10:30 AM
    Spatial Transcriptomic Profiling of Severe COVID-19 Patients
    Spatial Transcriptomic Profiling of Severe COVID-19 Patients
    Severe SARS-CoV-2 infection often leads to development of acute respiratory distress syndrome (ARDS), with profound pulmonary patho-histological changes post-mortem. In this study, we utiliz...
    Speaker: Camilla Margaroli, PhD
    Presented at: Coronavirus Series
    Sponsored By: NanoString Technologies
    2
    APR 21, 2021 | 12:00 AM
    Flex Analysis: A Safe, Integrated and Flexible Approach to Non-Invasive Aneuploidy Analysis
    Flex Analysis: A Safe, Integrated and Flexible Approach to Non-Invasive...
    NGS Bioinformatics software has come of age. Our workflows need software solutions that don’t only carry out the correct calculations to give the correct results reliably and unambiguo...
    Speaker: Matthew C. Forman, PhD
    Presented at: Genetics Week Virtual Event Series 2021
    1
    APR 07, 2021 | 12:00 AM
    Anti-fibrotic materials for immunoprotected cell-based therapies
    Anti-fibrotic materials for immunoprotected cell-based therapies
    Cell encapsulation within semi-permeable devices represents a local immunoisolation strategy for cell-based therapies without the need for systemic immunosuppression. The encapsulation syste...
    Speaker: Dr. Matthew Bochenek, PhD
    Presented at: Bioprocessing Virtual Event Series 2021
    1
     
     
  • SEP 09, 2020 | 10:00 AM
    Immunoprotective vs. immunopathogenic responses during fungal-associated allergic airway inflammation
    Immunoprotective vs. immunopathogenic responses during fungal-associated...
    Asthma is an increasing health concern affecting more than 25 million individuals in the United States and more than 300 million individuals worldwide. In some cases, sensitization or exposu...
    Speaker: Chad Steele, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    Sponsored By: Luminex - A DiaSorin Company
    1
    JUN 30, 2020 | 10:00 AM
    COVID-19 Serology Assays and Cell Therapy Strategies
    COVID-19 Serology Assays and Cell Therapy Strategies
    DATE: June 30, 2020 TIME: 10:00 am PDT, 1:00 pm EDT COVID-19 is a highly pathogenic disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We have assembled a panel...
    Speaker: Fatima Amanat , Dean Lee , Lior Raviv
    Sponsored By: Thermo Fisher Scientific/Gibco
    30 1
    JUN 17, 2020 | 3:00 PM
    Surgery as (Un)Usual: Development of Rodent Intracerebroventricular injection Capabilities During COVID-19
    Surgery as (Un)Usual: Development of Rodent Intracerebroventricular...
    Bringing a new research surgical model into production is always a challenging endeavor, and it has become much more challenging with the emergence of the Covid-19 pandemic. The virus’...
    Speaker: Matthew Flegal, BS, SRS
    Presented at: Coronavirus Series
    1
    JUN 04, 2020 | 2:00 PM
    Lipoma Preferred Partner (LPP) Regulates Breast Cancer Cell Migration and Invasion
    Lipoma Preferred Partner (LPP) Regulates Breast Cancer Cell Migration...
    In 2019, over 220,000 Canadians will be diagnosed with cancer and 82,000 will die of the disease. Approximately 90% of cancer related deaths are the result of metastatic disease. This is ind...
    Speaker: KEYNOTE: Claire Brown, PhD
    Presented at: Cell & Developmental Biology Virtual Meeting
    3
    JUN 03, 2020 | 12:00 AM
    Mining the molecular noise: fluorescence fluctuation image analysis of microscopy and super-resolution microscopy images reveals biomolecule interactions & transport maps in living cells
    Mining the molecular noise: fluorescence fluctuation image analysis...
    The transport properties of biomolecules in cells can reveal a great deal about the functional interactions regulating cells at the molecular level. Various biophysical methods have been dev...
    Speaker: Paul Wiseman, PhD
    Presented at: Cell & Developmental Biology Virtual Meeting
    2
     
     
  • MAY 09, 2019 | 10:30 AM
    Somatic Gene Recombination in the Brain
    Somatic Gene Recombination in the Brain
    Speculations that some form DNA alteration might be utilized by the brain date to the 1960s [1] wherein hypotheses for genomic alterations of germline DNA were proposed for immunoglobulins an...
    Speaker: Jerold Chun, MD, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2019
    2
    FEB 14, 2019 | 12:00 PM
    Application of Micro-Physiological Systems for Respiratory Drug Discovery: Opportunities and Challenges
    Application of Micro-Physiological Systems for Respiratory Drug...
    The lung is a highly complex organ, comprised of more than 40 cell types that are responsible for various important functions, the lung’s complexity contributes to the subsequent challe...
    Speaker: David Rowlands, PhD
    Presented at: Laboratory Animal Sciences Virtual Event Series 2019
    1
    DEC 10, 2018 | 10:00 PM
    Better Data, Fewer Mice: micro-CT Imaging Breathes New Life into your Lung Research
    Better Data, Fewer Mice: micro-CT Imaging Breathes New Life into...
    DATE: December 11, 2018TIME: 06:00 PSTIt’s understood and accepted that animal disease models generally offer great value for pre-clinical research and efficient drug screeni...
    Speaker: Dr. Christian Dullin , Dr. Sasha (Alexandre) Belenkov , Dr. Francesca Ruscitti
    Sponsored By: Revvity
    4 1
    NOV 15, 2018 | 6:00 AM
    LIVE TRAINING: Pluripotent Stem Cell Picking
    LIVE TRAINING: Pluripotent Stem Cell Picking
    Picking stem cells, whether it be for clone selection or general line maintenance is an important and useful technique that for stem cell researchers should be comfortable with...
    Speaker: Carl Dargitz
    Presented at: 6th annual 24 Hours of Stem Cellsâ„¢ virtual event
    6
    NOV 14, 2018 | 3:00 PM
    Modeling Inflammation and Fibrosis in Humans with PSC-derived Steatohepatitis Liver Organoids
    Modeling Inflammation and Fibrosis in Humans with PSC-derived...
    Neuronal migration defects, including pachygyria, are among the most severe developmental brain defects in humans. Using human genetics approaches, we recently identified bi-allelic truncatin...
    Speaker: Takanori Takebe
    Presented at: 6th annual 24 Hours of Stem Cellsâ„¢ virtual event
    8
     
     
  • SEP 13, 2018 | 6:00 AM
    The Hurricane Microbiome Project: Environmental Exposures and Population Health
    The Hurricane Microbiome Project: Environmental Exposures and...
    The Alkek Center for Metagenomics and Microbiome Research (CMMR) at Baylor College of Medicine is pursuing numerous research and development efforts in the study of how the microbiome impacts...
    Speaker: Joseph Petrosino, PhD
    Presented at: Microbiology & Immunology Virtual Event Series 2018
    1
    SEP 12, 2018 | 12:00 PM
    Antimicrobial Resistance Identification, Strain Typing, and Assay Design with CLC Genomics Workbench
    Antimicrobial Resistance Identification, Strain Typing, and Assay...
    Whole genome sequencing of bacterial isolates via next-generation sequencing is becoming a standard approach for clinical microbiology and bio-surveillance labs seeking to conduct outbreak in...
    Speaker: Winnie Ridderberg, PhD
    Presented at: Microbiology & Immunology Virtual Event Series 2018
    Sponsored By: QIAGEN
    3
    JUN 26, 2018 | 9:00 AM
    Automated In Vivo Efficacy Assessment in Preclinical Lung Disease Models
    Automated In Vivo Efficacy Assessment in Preclinical Lung Disease...
    Treatments for respiratory diseases represent an enormous, unmet medical need with limited therapies currently approved for use. Despite many compounds demonstrating beneficial effects in ani...
    Speaker: Laura Schaevitz, PhD
    Sponsored By: Vium
    6
    JUN 01, 2018 | 12:00 AM
    Embryonic Stem (ES) Cell FBS Qualified
    Embryonic Stem (ES) Cell FBS Qualified
    Thermo Fisher Scientific has developed an advanced assay to qualify FBS for use with ESCs.  This assay is designed to sustain undifferentiated ES cells while maintaining karyotype integr...
    Speaker: Carl Dargitz
    Presented at: 6th annual 24 Hours of Stem Cellsâ„¢ virtual event
    1
    MAY 09, 2018 | 10:30 AM
    The microRNA Regulatory Landscape of MSC-Derived Exosomes: A Systems View
    The microRNA Regulatory Landscape of MSC-Derived Exosomes: A Systems...
    Mesenchymal stem cell (MSC)-derived exosomes mediate tissue regeneration in a variety of diseases including ischemic heart injury, liver fibrosis, and cerebrovascular disease. Despite an incr...
    Speaker: Juliane Nguyen, PharmD, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2018
    Sponsored By: NanoString Technologies
    3
     
     
  • APR 12, 2018 | 9:00 AM
    Metabolites, Germs and People: Eavesdropping on Human Microbial Communities
    Metabolites, Germs and People: Eavesdropping on Human Microbial...
    The Whiteson lab uses culture-independent metagenomics, metabolomics, and ecological statistics along with hypothesis driven, reductionist microbiology to answer questions about how bacteria...
    Speaker: Katrine Whiteson, PhD
    Presented at: Molecular Diagnostics Virtual Event Series 2018
    1
    FEB 22, 2018 | 1:30 PM
    Recent Trends in GPCR Drug Discovery: Novel Targets, New Disease Indications, and an Upsurge in Biologics
    Recent Trends in GPCR Drug Discovery: Novel Targets, New Disease...
    GPCRs constitute the largest receptor family in the human genome. Over the years they have proven themselves to be druggable targets accounting for about 1/3 of all drugs on the market today....
    Speaker: Annette Gilchrist, PhD
    Presented at: Drug Discovery Virtual Event Series 2018
    1
    SEP 13, 2017 | 12:00 PM
    High Resolution Outbreak Tracing and Resistance Detection using Whole Genome Sequencing in the case of a Mycobacterium tuberculosis Outbreak
    High Resolution Outbreak Tracing and Resistance Detection using...
    Background: In March 2014, a molecular cluster of five multidrug resistant Mycobacterium tuberculosis was detected by the Austrian National Reference Laboratory. An investigation was initiate...
    Speaker: Winnie Ridderberg, PhD
    Presented at: Microbiology & Immunology Virtual Event Series 2017
    1
    JUN 14, 2017 | 6:00 AM
    WEBINAR: Accelerated Data Workflows for Biomarker Discovery in Metabolomics: Clinical Research Applications in Cystic Fibrosis Research
    WEBINAR: Accelerated Data Workflows for Biomarker Discovery in...
    DATE: June 14, 2017TIME: 6:00am PT, 9:00am ET, 3:00pm CETComprehensive metabolite profiling (i.e., metabolomics) offers a holistic approach for understanding the phenotype of an organis...
    Speaker: Philip Britz-McKibbin
    Sponsored By: Agilent
    4
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