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    Histone Modification

    A histone modification is a covalent post-translational modification (PTM) to histone proteins which includes methylation, phosphorylation, acetylation, ubiquitylation, and sumoylation. The PTMs made to histones can impact gene expression by altering chromatin structure or recruiting histone modifiers. Histone proteins act to package DNA, which wraps around the eight histones, into chromosomes. Histone modifications act in diverse biological processes such as transcriptional activation/inactivation, chromosome packaging, and DNA damage/repair.

    Trending News

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      OCT 31, 2019
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      OCT 24, 2019
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      SEP 21, 2019
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      JAN 22, 2019
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      OCT 23, 2018
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      JUN 26, 2018
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      MAY 17, 2018
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      Epigenetic Similarities Between Rheumatoid Arthritis and Huntington's Disease
      A detailed investigation into the epigenome of rheumatoid arthritis (RA) patients revealed unexpected similarities betwe ...
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      DEC 17, 2017
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      AUG 16, 2017
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      NOV 20, 2016
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      SEP 18, 2016
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      MAY 14, 2015
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      APR 22, 2015
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      AUG 22, 2014
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    APR 03, 2020
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    Less than a millisecond after a cell is stretched out, genes are activated, which will result in the production of prote ...
    Written By: Carmen Leitch
    3
    OCT 31, 2019
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    Unpacking lactate's role in the Warburg effect
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    In a recent issue of Nature, the findings of one study made a particularly big splash: how and why cancer cells use ener ...
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    1
    OCT 24, 2019
    Neuroscience
    Alcohol Consumption Linked to Epigenetic Changes in Brain Memory System
    Alcohol Consumption Linked to Epigenetic Changes in Brain Memory System
    For a recovering alcoholic, walking past a familiar bar or attending social events are often challenging situations. In ...
    Written By: Dr. Nina Lichtenberg
    1
    SEP 21, 2019
    Cell & Molecular Biology
    Insight Into the Epigenetic Mechanisms Controlling Cellular Identity
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    Every cell type has to carefully control which genes are expressed, and new research has learned more about that process ...
    Written By: Carmen Leitch
    2
    JAN 22, 2019
    Genetics & Genomics
    Towards a Better Understanding of Genetic Modifications in Plants
    Towards a Better Understanding of Genetic Modifications in Plants
    Scientists have taken a close look at what happens on the molecular level when DNA is inserted into the genome of a plan ...
    Written By: Carmen Leitch
    1
     
     
  • OCT 23, 2018
    Genetics & Genomics
    Sperm Can Pass Epigenetic Information Onto Offspring
    Sperm Can Pass Epigenetic Information Onto Offspring
    We are born with a genome that doesn't change, but small modifications can be made to that genetic material throughout o ...
    Written By: Carmen Leitch
    1
    JUN 26, 2018
    Cancer
    Five "-omics" Fields Introduced
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    Written By: Mauri Brueggeman
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    MAY 21, 2018
    Cancer
    Epigenetics & Cancer: DNA Modification Impacts
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    Written By: Mauri Brueggeman
    3
    MAY 17, 2018
    Immunology
    Epigenetic Similarities Between Rheumatoid Arthritis and Huntington's Disease
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    Written By: Kara Marker
    3 1
    DEC 17, 2017
    Drug Discovery & Development
    Epigenetic Drugs: Promising Therapeutics
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  • AUG 16, 2017
    Microbiology
    Cancer drugs take aim at viruses
    Cancer drugs take aim at viruses
    Researchers at the National Institute of Allergy and Infectious Disease knew that some viruses - herpes simplex virus, f ...
    Written By: Kerry Evans
    2
    JAN 31, 2017
    Genetics & Genomics
    Gene Essential for Reprogramming Human Amniotic Stem Cells
    Gene Essential for Reprogramming Human Amniotic Stem Cells
    Gene Essential for Reprogramming Human Amniotic Stem Cells
    Written By: Jennifer Ellis
    2
    NOV 20, 2016
    Cell & Molecular Biology
    Similar Epigenetic Changes Seen in Various Types of Autism
    Similar Epigenetic Changes Seen in Various Types of Autism
    A study published in Cell demonstrated how the brains of patients with different kinds of autism spectrum disorder (ASD) ...
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    4
    SEP 18, 2016
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    New Probe Detects Histone Modifications in Live Cells
    New Probe Detects Histone Modifications in Live Cells
    Researchers have created a new, fluorescent probe that detects a specific methyl group on histones in living cells. This ...
    Written By: Carmen Leitch
    2 1
    MAY 14, 2015
    Genetics & Genomics
    Long Non-Coding RNAs Steer Bodily Functions
    Long Non-Coding RNAs Steer Bodily Functions
    Understanding the function of certain groups of non-coding RNAs will lead to a greater understanding of how certain illn ...
    Written By: Ilene Schneider
    8 3
     
     
  • APR 22, 2015
    Genetics & Genomics
    Steering the epigenome to turn on specific genes
    Steering the epigenome to turn on specific genes
    Could the epigenome provide a new avenue for gene therapies and guiding stem cell differentiation?

    Written By: Robert Woodard
    5
    AUG 22, 2014
    Genetics & Genomics
    It
    It
    Epigenetics has a large say in blood formation.

    Blood stem cells have the potential to turn into any type of ...
    Written By: Ilene Schneider
    3
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