Liver diseases are characterized by their damaging impacts on hepatic tissue. Many liver diseases are caused by viruses, such as hepatitis A, B, and C. Other liver diseases, including cirrhosis, can also be driven by drug or alcohol abuse, and exposure to toxins or poisons. Additionally, some liver diseases, such as Wilson disease, are genetically passed through generations.
DATE: November 13, 2018TIME: 9:00am PST, 12:00pm ESTExtracellular vesicles (EVs) are cell-secreted nanoparticles that play a pivotal role in intercellular communic...
Complex disease phenotypes - obesity, type II diabetes, and cancer challenge simple models in both evolution and biology. Examination of molecular networks and their dynamic behavior o...
Mesenchymal stem cell (MSC)-derived exosomes mediate tissue regeneration in a variety of diseases including ischemic heart injury, liver fibrosis, and cerebrovascular disease. Despite an incr...
Free 25OH Vitamin D has received increasing attention over the last four years. More and more studies support the importance of free 25OH Vitamin D, suggesting that this fraction of 25OH Vita...
Adult stem cell research is one of the most dynamic and fast growing fields of our time. Investigating how organs maintain and repair themselves has led to the discovery of cell populations t...
DATE: October 4th, 2017TIME: 8:00AM PT, 11:00AM ET, 5:00PM (GMT+2)New HCV drugs are now approved which, when used in combination, yield very high rates of cure of HC...
DATE: May 23, 2017TIME: 10:00am PT, 1:00pm ETA number of studies have shown that vitamin D deficiency is very common in both the developing and developed world. This has increased the i...
The study of inherited genomic variation through genome wide association studies (GWAS) promised to provide key biologic insight into common diseases of public health significance such as obe...
DATE: February 9, 2017TIME: 9:00am PT, 12:00pm ETTraditional models of liver fibrosis in rodents involve many weeks of induction, with frequent injections of a pro-fibrotic agent. The m...
Join Dr Javier Conde Vancells as he reviews the use of primary and secondary antibody conjugates across multiple lab applications, including a review of direct vs. indirect methods in cellula...
DATE: December 7, 2016TIME: 8:00am PT, 11:00am ET1,25-dihydroxyvitamin D (1,25[OH]2D) is the active, hormonal form of vitamin D. It is produced from its precursor (vitamin D) by two hyd...
The mission of the California Institute for Regenerative Medicine (CIRM) is to accelerate stem cell treatments to patients with unmet medical needs. With $3 billion in funding and 300 a...
Hepatocellular Carcinoma (HCC) and Endometrioid Endometrial Carcinoma (EEC) are two lethal diseases of public health importance worldwide. Understanding the mechanisms of tumor progression in...
In healthy liver, quiescent hepatic stellate cells (HSCs) participate in the homeostasis of extracellular matrix and store vitamin A. After injury, HSCs activate and participate in the wound-...
In the last 10 years, PCSK9 emerged as a promising target for the treatment of autosomal dominant hypercholesterolemia (ADH). With the emergence of induced pluripotent stem (hiPS) cells and f...
Using human pluripotent stem cells as a screening platform, we have identified a novel cell surface maker that identifies foregut endoderm progenitors in pancreas and liver. We have sho...
Hepatocellular Carcinoma (HCC), the third leading cause of global cancer mortality, continues to be a substantial burden to health systems, society and individuals at risk. Although prognosis...
Emerging technologies facilitate basic science research, but their value in regulatory applications requires rigorous assessment and consensus within the research community. Next-generation s...
We have been developing methods to target drugs specifically to pathologic cells, thereby avoiding collateral toxicity to healthy cells. In the case of cancer, we have exploited up-regulation...
Multidimensional molecular characterization has led to a tsunami of cancer data. Precision Medicine assumes that new understanding and better interventions will flow from this “Big Data...
We have been developing methods to target drugs specifically to pathologic cells, thereby avoiding collateral toxicity to healthy cells. In the case of cancer, we have exploited up-regulation...
The comprehensive, multidimensional molecular characterization of tumors and the individuals in which they have developed is transforming cancer definition, diagnosis, treatment, and preventi...
The comprehensive, multidimensional molecular characterization of tumors and the individuals in which they have developed is transforming cancer definition, diagnosis, treatment, and preventi...
Traditional testing methods for monoclonal protein in Plasma Cell Dyscrasias correctly identify a majority of patients. However, limitations in these methods can cause patients to be missed...
DATE: November 13, 2018TIME: 9:00am PST, 12:00pm ESTExtracellular vesicles (EVs) are cell-secreted nanoparticles that play a pivotal role in intercellular communic...
Complex disease phenotypes - obesity, type II diabetes, and cancer challenge simple models in both evolution and biology. Examination of molecular networks and their dynamic behavior o...
Mesenchymal stem cell (MSC)-derived exosomes mediate tissue regeneration in a variety of diseases including ischemic heart injury, liver fibrosis, and cerebrovascular disease. Despite an incr...
Free 25OH Vitamin D has received increasing attention over the last four years. More and more studies support the importance of free 25OH Vitamin D, suggesting that this fraction of 25OH Vita...
Adult stem cell research is one of the most dynamic and fast growing fields of our time. Investigating how organs maintain and repair themselves has led to the discovery of cell populations t...
DATE: October 4th, 2017TIME: 8:00AM PT, 11:00AM ET, 5:00PM (GMT+2)New HCV drugs are now approved which, when used in combination, yield very high rates of cure of HC...
DATE: May 23, 2017TIME: 10:00am PT, 1:00pm ETA number of studies have shown that vitamin D deficiency is very common in both the developing and developed world. This has increased the i...
The study of inherited genomic variation through genome wide association studies (GWAS) promised to provide key biologic insight into common diseases of public health significance such as obe...
DATE: February 9, 2017TIME: 9:00am PT, 12:00pm ETTraditional models of liver fibrosis in rodents involve many weeks of induction, with frequent injections of a pro-fibrotic agent. The m...
Join Dr Javier Conde Vancells as he reviews the use of primary and secondary antibody conjugates across multiple lab applications, including a review of direct vs. indirect methods in cellula...
DATE: December 7, 2016TIME: 8:00am PT, 11:00am ET1,25-dihydroxyvitamin D (1,25[OH]2D) is the active, hormonal form of vitamin D. It is produced from its precursor (vitamin D) by two hyd...
The mission of the California Institute for Regenerative Medicine (CIRM) is to accelerate stem cell treatments to patients with unmet medical needs. With $3 billion in funding and 300 a...
Hepatocellular Carcinoma (HCC) and Endometrioid Endometrial Carcinoma (EEC) are two lethal diseases of public health importance worldwide. Understanding the mechanisms of tumor progression in...
In healthy liver, quiescent hepatic stellate cells (HSCs) participate in the homeostasis of extracellular matrix and store vitamin A. After injury, HSCs activate and participate in the wound-...
In the last 10 years, PCSK9 emerged as a promising target for the treatment of autosomal dominant hypercholesterolemia (ADH). With the emergence of induced pluripotent stem (hiPS) cells and f...
Using human pluripotent stem cells as a screening platform, we have identified a novel cell surface maker that identifies foregut endoderm progenitors in pancreas and liver. We have sho...
Hepatocellular Carcinoma (HCC), the third leading cause of global cancer mortality, continues to be a substantial burden to health systems, society and individuals at risk. Although prognosis...
Emerging technologies facilitate basic science research, but their value in regulatory applications requires rigorous assessment and consensus within the research community. Next-generation s...
We have been developing methods to target drugs specifically to pathologic cells, thereby avoiding collateral toxicity to healthy cells. In the case of cancer, we have exploited up-regulation...
Multidimensional molecular characterization has led to a tsunami of cancer data. Precision Medicine assumes that new understanding and better interventions will flow from this “Big Data...
We have been developing methods to target drugs specifically to pathologic cells, thereby avoiding collateral toxicity to healthy cells. In the case of cancer, we have exploited up-regulation...
The comprehensive, multidimensional molecular characterization of tumors and the individuals in which they have developed is transforming cancer definition, diagnosis, treatment, and preventi...
The comprehensive, multidimensional molecular characterization of tumors and the individuals in which they have developed is transforming cancer definition, diagnosis, treatment, and preventi...
Traditional testing methods for monoclonal protein in Plasma Cell Dyscrasias correctly identify a majority of patients. However, limitations in these methods can cause patients to be missed...
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