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    Monoclonal proteins

    Monoclonal proteins, also called M proteins, are elevated in the blood and urine of patients with multiple myeloma or monoclonal gammopathy of undetermined significance (MGUS), a condition which is highly correlated to bone marrow and blood cancers. Monoclonal proteins are antibodies produced in the bone marrow by the cancerous cells.

    Webinars

    • DEC 05, 2023 | 3:00 PM
      Revolutionizing Drug Development: Synthetic Nanodiscs
      Revolutionizing Drug Development: Synthetic Nanodiscs
      Most FDA-approved therapeutic drugs target transmembrane proteins, yet the development of monoclonal antibodies for multi-transmembrane protein targets has been limited. Despite the abundanc...
      Speaker: Dr. Donghui Ma
      Sponsored By: DIMA Biotech
      11
      JUN 27, 2023 | 10:00 AM
      Challenges in Monoclonal Free Light Chain Measurements
      Challenges in Monoclonal Free Light Chain Measurements
      There is a great variability in testing for monoclonal gammopathies. During his presentation, Dr. David F. Keren, MD, Clinical Professor of Pathology at University of Michigan Health, descri...
      Speaker: David F. Keren, MD
      Sponsored By: Siemens Healthineers
      9
      APR 13, 2023 | 8:00 AM
      Novel subunit analysis for biotherapeutic development: increased coverage from a single injection
      Novel subunit analysis for biotherapeutic development: increased...
      Date: April 13, 2023 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) It is important to confirm the sequences and post-translational modifications (PTMs) of protein therapeutics to ensure d...
      Speaker: Haichuan Liu
      Sponsored By: SCIEX
      6
      FEB 22, 2023 | 10:30 AM
      Using Single B Technology to Develop Lead Antibody Molecules on GPCR Targets with Live Q&A
      Using Single B Technology to Develop Lead Antibody Molecules on...
      Immunogens with native conformation and a high-throughput IgG cloning platform are two of the most important key components for high quality lead antibody molecules discovery. DIMABIO’...
      Speaker: Donghui Ma, PhD
      Presented at: Drug Discovery & Development Virtual Event Series 2023
      Sponsored By: DIMA Biotech
      3
      FEB 09, 2023 | 9:00 AM
      A Modern Approach to Screening for Monoclonal Gammopathies using Digital Workflows
      A Modern Approach to Screening for Monoclonal Gammopathies using...
      Date: February 09, 2023 Time: 9:00am (PST), 12:00pm (EST), 6:00pm (CET) Monoclonal gammopathies (MGs) comprise a broad set of diseases involving the abnormal clonal proliferation of plasma c...
      Speaker: Mark Zaydman, M.D., Ph.D.
      Sponsored By: Sebia, Inc.
      22
      JUN 22, 2022 | 10:00 AM
      Making Therapeutic Antibodies Simple, Fast and Safe
      Making Therapeutic Antibodies Simple, Fast and Safe
      Date: June 22, 2022 Time: 10:00am (PDT), 1:00pm (EDT), 7:00pm (CEST) Rabbits have a robust and unique immune system that enables the generated antibodies with superior specificity, affinity,...
      Speaker: Lidan Ding
      Sponsored By: GenScript
      17
      JUN 01, 2022 | 9:00 AM
      Analysis of process related impurities in cell & gene therapy products by SWATH LC-MS
      Analysis of process related impurities in cell & gene therapy...
      Date: June 01, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) The manufacturing process for cell and gene therapies is complex and can contain process-related impurities from multiple...
      Speaker: Ejvind Mørtz
      Sponsored By: SCIEX
      3
      APR 06, 2022 | 9:00 AM
      Keynote Presentation: Continuous Bioprocessing - New Challenges and Opportunities for Membrane Technology
      Keynote Presentation: Continuous Bioprocessing - New Challenges...
      There is growing interest in the development of integrated continuous bioprocesses for the production of important biotherapeutics due to the potential for enhanced productivity, greater fle...
      Speaker: Andrew L. Zydney, PhD
      Presented at: Bioprocessing Virtual Event Series 2022
      1
      APR 06, 2022 | 5:30 AM
      Optimising Cell Line Development for Bioprocessing
      Optimising Cell Line Development for Bioprocessing
      In the last decades, the upstream processing in biopharma industry has been revolutionized regarding the production of bioactive materials such as monoclonal antibodies, proteins and biother...
      Speaker: Sami Ullah, PhD
      Presented at: Bioprocessing Virtual Event Series 2022
      4
      MAR 01, 2022 | 9:00 AM
      CAP Guidelines for Laboratory Detection and Initial Diagnosis of Monoclonal Gammopathies
      CAP Guidelines for Laboratory Detection and Initial Diagnosis...
      Date: March 1, 2022 Time: 9:00am (PST), 12:00pm (EST) Dr. David F Keren currently serves as a Professor of Pathology at the University of Michigan (Michigan Medicine). Dr. Keren received his...
      Speaker: David F. Keren, MD
      Sponsored By: Binding Site
      9 2
      FEB 23, 2022 | 11:55 PM
      Identification of Novel Protein Biomarkers in the Era of Precision Medicine Oncology
      Identification of Novel Protein Biomarkers in the Era of Precision...
      Cancer is a leading cause of morbidity and mortality in developed countries including the United States. Early detection of various cancers, before they spread and become incurable, has been...
      Speaker: Hilal Arnouk, MD, PhD
      Presented at: Drug Discovery & Development Virtual Event Series 2022
      3
      DEC 08, 2021 | 7:00 AM
      Troubleshooting in bioprocessing
      Troubleshooting in bioprocessing
      Date: December 08, 2021 Time: 7:00am (PDT), 10:00am (EDT) Successful bioprocessing is complex and depends on many factors. From the selection of the expression host, media composition, the p...
      Speaker: Ines Hartmann , Eric Timmermans
      Sponsored By: Eppendorf
      12
      NOV 17, 2021 | 9:00 AM
      Transform your timelines: Cut development time through multi-capillary CE-SDS and cIEF analysis of mAbs and mAb variants
      Transform your timelines: Cut development time through multi-capillary...
      Date: November 18, 2021 Time: 9:00am (PDT), 12:00pm (EDT) Therapeutic proteins such as monoclonal antibodies (mAbs) and mAb variants have been successfully applied in the treatment of cancer...
      Speaker: Marcia Santos
      Sponsored By: SCIEX
      2
      NOV 10, 2021 | 6:00 AM
      High-throughput, high resolution purity and heterogeneity characterization of biologics using breakthrough multi-capillary technology
      High-throughput, high resolution purity and heterogeneity characterization...
      Date: November 10, 2021 Time: 6:00am (PST), 9:00am (EST) Over the last 20 years, automated capillary electrophoresis (CE) has become an industry-preferred technique for quantitative purity a...
      Speaker: Fang Wang, PhD
      Sponsored By: SCIEX
      4
      NOV 04, 2021 | 10:00 AM
      A Clinical Chemist's Perspective of the Benefits and Limitations of Fecal Calprotectin Testing
      A Clinical Chemist's Perspective of the Benefits and Limitations...
      Date: November 04, 2021 Time: 10:00am (PDT), 1:00pm (EDT) Fecal calprotectin is a highly sensitive assay that measures inflammation present in the intestinal tract. Gastroenterologists are i...
      Speaker: Dr. Lisa Johnson
      Sponsored By: Diasorin
      5
      OCT 20, 2021 | 2:30 PM
      Structural Characterization of Short Oligonucleotide Therapeutics by Solution NMR
      Structural Characterization of Short Oligonucleotide Therapeutics...
      Short oligonucleotides are an emerging platform for the development of biopharmaceuticals to treat various diseases, including those that are inaccessible to small molecule- and protein-base...
      Speaker: Owen Becette, PhD
      Presented at: Analytical Chemistry & Separation Sciences Virtual Event Series 2021
      8
      OCT 20, 2021 | 9:00 AM
      Comprehensive analysis of next generation biologics using advanced data interpretation software
      Comprehensive analysis of next generation biologics using advanced...
      Date: October 20, 2021 Time: 9:00am (PDT), 12:00pm (EDT) Protein therapeutics is one of the major drug modalities in biopharma industry. With more and more elucidation of disease pathology,...
      Speaker: Zoe Zhang
      Sponsored By: SCIEX
      27
      OCT 20, 2021 | 9:00 AM
      Membrane Proteins: From gene to cryo-EM structure with Thermo Fisher GeneArt and Salipro Biotech
      Membrane Proteins: From gene to cryo-EM structure with Thermo...
      Date: October 20, 2021 Time: 9:00am PDT Cryo-electron microscopy (cryo-EM) is rapidly evolving to be the primary tool for structure determination of membrane proteins. However, generation of...
      Speaker: Ieva Drulyte, PhD , Michael Liss, PhD , Jens Frauenfeld, PhD
      Presented at: Thermo Fisher Scientific - Electron Microscopy Webinars
      Sponsored By: Thermo Fisher Scientific
      4
      OCT 13, 2021 | 6:00 AM
      Keynote Presentation: Discovery and Biology of Protective SARS-CoV-2 Human Monoclonal Antibodies
      Keynote Presentation: Discovery and Biology of Protective SARS-CoV-2...
      We’ll discuss the rapid discovery efforts to identify human monoclonal antibody drugs that protect against COVID-19. We will review the technologies used to find antibodies, the optima...
      Speaker: James Crowe, MD
      Presented at: Coronavirus Series
      26
      OCT 07, 2021 | 8:00 AM
      SARS-CoV-2 specific B cell detection and therapeutic antibody discovery
      SARS-CoV-2 specific B cell detection and therapeutic antibody...
      Date: October 7, 2021 Time: 8:00am (PDT), 11:00am (EDT) To combat the COVID-19 pandemic, comprehensive characterization of humoral and cellular immune responses to SARS-CoV-2 is essential. A...
      Speaker: Cristina Conforti Andreoni
      Sponsored By: Miltenyi Biotec
      15
      JUL 22, 2021 | 12:45 PM
      CRISPR/Cas9-based genome editing for autologous CAR-T cell production
      CRISPR/Cas9-based genome editing for autologous CAR-T cell production
      Gene editing technologies such as CRISPR/Cas9 have greater flexibility and high efficiency. CRISPR technology enables targeted insertion of transgenes at the desired locus and has the abilit...
      Speaker: Ramarao Vepachedu, PhD
      Presented at: GenScript Gene & Cell Engineering Virtual Summit
      3
      JUL 15, 2021 | 2:00 PM
      C.E. CREDITS
      Lupus anticoagulants and antiphospholipid syndrome: Resolving confusion, providing new guideline updates
      Lupus anticoagulants and antiphospholipid syndrome: Resolving...
      Join our session on antiphospholipid syndrome covering diagnosis, antibody testing, guideline updates, and clinical insights....
      Speaker: Thomas Ortel, MD, PhD
      Presented at: Stago EdVantage Virtual University
      Sponsored By: Diagnostica Stago, Inc.
      11
      JUL 13, 2021 | 11:00 AM
      Monoclonality Assurance Using CloneSelect Single-Cell Printer and CloneSelect Imager in Human Stem Cell (hSC) Engineering Workflow
      Monoclonality Assurance Using CloneSelect Single-Cell Printer...
      Date: July 13, 2021 Time: 11:00am (PDT), 1:00pm (EDT) 1 R&D, Cell Culture & Fermentation Sciences, Bio Pharmaceutical Development, AstraZeneca, Gaithersburg, USA, 2 R&D, ADPE, Ce...
      Speaker: Gargi Roy
      Sponsored By: Molecular Devices
      9 10
      JUN 22, 2021 | 10:00 AM
      Role of Cov-2 Serology in a vaccinated world
      Role of Cov-2 Serology in a vaccinated world
      Date: June 22, 2021 Time: 10:00am PST The objectives of this presentation are (1) to review current and emerging SARS-CoV-2 serology applications, (2) to discuss variation among different SA...
      Speaker: David M. Engman, MD, PhD
      Sponsored By: Diasorin
      25
    DEC 05, 2023 | 3:00 PM
    Revolutionizing Drug Development: Synthetic Nanodiscs
    Revolutionizing Drug Development: Synthetic Nanodiscs
    Most FDA-approved therapeutic drugs target transmembrane proteins, yet the development of monoclonal antibodies for multi-transmembrane protein targets has been limited. Despite the abundanc...
    Speaker: Dr. Donghui Ma
    Sponsored By: DIMA Biotech
    11
    JUN 27, 2023 | 10:00 AM
    Challenges in Monoclonal Free Light Chain Measurements
    Challenges in Monoclonal Free Light Chain Measurements
    There is a great variability in testing for monoclonal gammopathies. During his presentation, Dr. David F. Keren, MD, Clinical Professor of Pathology at University of Michigan Health, descri...
    Speaker: David F. Keren, MD
    Sponsored By: Siemens Healthineers
    9
    APR 13, 2023 | 8:00 AM
    Novel subunit analysis for biotherapeutic development: increased coverage from a single injection
    Novel subunit analysis for biotherapeutic development: increased...
    Date: April 13, 2023 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) It is important to confirm the sequences and post-translational modifications (PTMs) of protein therapeutics to ensure d...
    Speaker: Haichuan Liu
    Sponsored By: SCIEX
    6
    FEB 22, 2023 | 10:30 AM
    Using Single B Technology to Develop Lead Antibody Molecules on GPCR Targets with Live Q&A
    Using Single B Technology to Develop Lead Antibody Molecules on...
    Immunogens with native conformation and a high-throughput IgG cloning platform are two of the most important key components for high quality lead antibody molecules discovery. DIMABIO’...
    Speaker: Donghui Ma, PhD
    Presented at: Drug Discovery & Development Virtual Event Series 2023
    Sponsored By: DIMA Biotech
    3
    FEB 09, 2023 | 9:00 AM
    A Modern Approach to Screening for Monoclonal Gammopathies using Digital Workflows
    A Modern Approach to Screening for Monoclonal Gammopathies using...
    Date: February 09, 2023 Time: 9:00am (PST), 12:00pm (EST), 6:00pm (CET) Monoclonal gammopathies (MGs) comprise a broad set of diseases involving the abnormal clonal proliferation of plasma c...
    Speaker: Mark Zaydman, M.D., Ph.D.
    Sponsored By: Sebia, Inc.
    22
     
     
  • JUN 22, 2022 | 10:00 AM
    Making Therapeutic Antibodies Simple, Fast and Safe
    Making Therapeutic Antibodies Simple, Fast and Safe
    Date: June 22, 2022 Time: 10:00am (PDT), 1:00pm (EDT), 7:00pm (CEST) Rabbits have a robust and unique immune system that enables the generated antibodies with superior specificity, affinity,...
    Speaker: Lidan Ding
    Sponsored By: GenScript
    17
    JUN 01, 2022 | 9:00 AM
    Analysis of process related impurities in cell & gene therapy products by SWATH LC-MS
    Analysis of process related impurities in cell & gene therapy...
    Date: June 01, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) The manufacturing process for cell and gene therapies is complex and can contain process-related impurities from multiple...
    Speaker: Ejvind Mørtz
    Sponsored By: SCIEX
    3
    APR 06, 2022 | 9:00 AM
    Keynote Presentation: Continuous Bioprocessing - New Challenges and Opportunities for Membrane Technology
    Keynote Presentation: Continuous Bioprocessing - New Challenges...
    There is growing interest in the development of integrated continuous bioprocesses for the production of important biotherapeutics due to the potential for enhanced productivity, greater fle...
    Speaker: Andrew L. Zydney, PhD
    Presented at: Bioprocessing Virtual Event Series 2022
    1
    APR 06, 2022 | 5:30 AM
    Optimising Cell Line Development for Bioprocessing
    Optimising Cell Line Development for Bioprocessing
    In the last decades, the upstream processing in biopharma industry has been revolutionized regarding the production of bioactive materials such as monoclonal antibodies, proteins and biother...
    Speaker: Sami Ullah, PhD
    Presented at: Bioprocessing Virtual Event Series 2022
    4
    MAR 01, 2022 | 9:00 AM
    CAP Guidelines for Laboratory Detection and Initial Diagnosis of Monoclonal Gammopathies
    CAP Guidelines for Laboratory Detection and Initial Diagnosis...
    Date: March 1, 2022 Time: 9:00am (PST), 12:00pm (EST) Dr. David F Keren currently serves as a Professor of Pathology at the University of Michigan (Michigan Medicine). Dr. Keren received his...
    Speaker: David F. Keren, MD
    Sponsored By: Binding Site
    9 2
     
     
  • FEB 23, 2022 | 11:55 PM
    Identification of Novel Protein Biomarkers in the Era of Precision Medicine Oncology
    Identification of Novel Protein Biomarkers in the Era of Precision...
    Cancer is a leading cause of morbidity and mortality in developed countries including the United States. Early detection of various cancers, before they spread and become incurable, has been...
    Speaker: Hilal Arnouk, MD, PhD
    Presented at: Drug Discovery & Development Virtual Event Series 2022
    3
    DEC 08, 2021 | 7:00 AM
    Troubleshooting in bioprocessing
    Troubleshooting in bioprocessing
    Date: December 08, 2021 Time: 7:00am (PDT), 10:00am (EDT) Successful bioprocessing is complex and depends on many factors. From the selection of the expression host, media composition, the p...
    Speaker: Ines Hartmann , Eric Timmermans
    Sponsored By: Eppendorf
    12
    NOV 17, 2021 | 9:00 AM
    Transform your timelines: Cut development time through multi-capillary CE-SDS and cIEF analysis of mAbs and mAb variants
    Transform your timelines: Cut development time through multi-capillary...
    Date: November 18, 2021 Time: 9:00am (PDT), 12:00pm (EDT) Therapeutic proteins such as monoclonal antibodies (mAbs) and mAb variants have been successfully applied in the treatment of cancer...
    Speaker: Marcia Santos
    Sponsored By: SCIEX
    2
    NOV 10, 2021 | 6:00 AM
    High-throughput, high resolution purity and heterogeneity characterization of biologics using breakthrough multi-capillary technology
    High-throughput, high resolution purity and heterogeneity characterization...
    Date: November 10, 2021 Time: 6:00am (PST), 9:00am (EST) Over the last 20 years, automated capillary electrophoresis (CE) has become an industry-preferred technique for quantitative purity a...
    Speaker: Fang Wang, PhD
    Sponsored By: SCIEX
    4
    NOV 04, 2021 | 10:00 AM
    A Clinical Chemist's Perspective of the Benefits and Limitations of Fecal Calprotectin Testing
    A Clinical Chemist's Perspective of the Benefits and Limitations...
    Date: November 04, 2021 Time: 10:00am (PDT), 1:00pm (EDT) Fecal calprotectin is a highly sensitive assay that measures inflammation present in the intestinal tract. Gastroenterologists are i...
    Speaker: Dr. Lisa Johnson
    Sponsored By: Diasorin
    5
     
     
  • OCT 20, 2021 | 2:30 PM
    Structural Characterization of Short Oligonucleotide Therapeutics by Solution NMR
    Structural Characterization of Short Oligonucleotide Therapeutics...
    Short oligonucleotides are an emerging platform for the development of biopharmaceuticals to treat various diseases, including those that are inaccessible to small molecule- and protein-base...
    Speaker: Owen Becette, PhD
    Presented at: Analytical Chemistry & Separation Sciences Virtual Event Series 2021
    8
    OCT 20, 2021 | 9:00 AM
    Comprehensive analysis of next generation biologics using advanced data interpretation software
    Comprehensive analysis of next generation biologics using advanced...
    Date: October 20, 2021 Time: 9:00am (PDT), 12:00pm (EDT) Protein therapeutics is one of the major drug modalities in biopharma industry. With more and more elucidation of disease pathology,...
    Speaker: Zoe Zhang
    Sponsored By: SCIEX
    27
    OCT 20, 2021 | 9:00 AM
    Membrane Proteins: From gene to cryo-EM structure with Thermo Fisher GeneArt and Salipro Biotech
    Membrane Proteins: From gene to cryo-EM structure with Thermo...
    Date: October 20, 2021 Time: 9:00am PDT Cryo-electron microscopy (cryo-EM) is rapidly evolving to be the primary tool for structure determination of membrane proteins. However, generation of...
    Speaker: Ieva Drulyte, PhD , Michael Liss, PhD , Jens Frauenfeld, PhD
    Presented at: Thermo Fisher Scientific - Electron Microscopy Webinars
    Sponsored By: Thermo Fisher Scientific
    4
    OCT 13, 2021 | 6:00 AM
    Keynote Presentation: Discovery and Biology of Protective SARS-CoV-2 Human Monoclonal Antibodies
    Keynote Presentation: Discovery and Biology of Protective SARS-CoV-2...
    We’ll discuss the rapid discovery efforts to identify human monoclonal antibody drugs that protect against COVID-19. We will review the technologies used to find antibodies, the optima...
    Speaker: James Crowe, MD
    Presented at: Coronavirus Series
    26
    OCT 07, 2021 | 8:00 AM
    SARS-CoV-2 specific B cell detection and therapeutic antibody discovery
    SARS-CoV-2 specific B cell detection and therapeutic antibody...
    Date: October 7, 2021 Time: 8:00am (PDT), 11:00am (EDT) To combat the COVID-19 pandemic, comprehensive characterization of humoral and cellular immune responses to SARS-CoV-2 is essential. A...
    Speaker: Cristina Conforti Andreoni
    Sponsored By: Miltenyi Biotec
    15
     
     
  • JUL 22, 2021 | 12:45 PM
    CRISPR/Cas9-based genome editing for autologous CAR-T cell production
    CRISPR/Cas9-based genome editing for autologous CAR-T cell production
    Gene editing technologies such as CRISPR/Cas9 have greater flexibility and high efficiency. CRISPR technology enables targeted insertion of transgenes at the desired locus and has the abilit...
    Speaker: Ramarao Vepachedu, PhD
    Presented at: GenScript Gene & Cell Engineering Virtual Summit
    3
    JUL 15, 2021 | 2:00 PM
    C.E. CREDITS
    Lupus anticoagulants and antiphospholipid syndrome: Resolving confusion, providing new guideline updates
    Lupus anticoagulants and antiphospholipid syndrome: Resolving...
    Join our session on antiphospholipid syndrome covering diagnosis, antibody testing, guideline updates, and clinical insights....
    Speaker: Thomas Ortel, MD, PhD
    Presented at: Stago EdVantage Virtual University
    Sponsored By: Diagnostica Stago, Inc.
    11
    JUL 13, 2021 | 11:00 AM
    Monoclonality Assurance Using CloneSelect Single-Cell Printer and CloneSelect Imager in Human Stem Cell (hSC) Engineering Workflow
    Monoclonality Assurance Using CloneSelect Single-Cell Printer...
    Date: July 13, 2021 Time: 11:00am (PDT), 1:00pm (EDT) 1 R&D, Cell Culture & Fermentation Sciences, Bio Pharmaceutical Development, AstraZeneca, Gaithersburg, USA, 2 R&D, ADPE, Ce...
    Speaker: Gargi Roy
    Sponsored By: Molecular Devices
    9 10
    JUN 22, 2021 | 10:00 AM
    Role of Cov-2 Serology in a vaccinated world
    Role of Cov-2 Serology in a vaccinated world
    Date: June 22, 2021 Time: 10:00am PST The objectives of this presentation are (1) to review current and emerging SARS-CoV-2 serology applications, (2) to discuss variation among different SA...
    Speaker: David M. Engman, MD, PhD
    Sponsored By: Diasorin
    25
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