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    Monoclonal proteins

    Monoclonal proteins, also called M proteins, are elevated in the blood and urine of patients with multiple myeloma or monoclonal gammopathy of undetermined significance (MGUS), a condition which is highly correlated to bone marrow and blood cancers. Monoclonal proteins are antibodies produced in the bone marrow by the cancerous cells.

    Webinars

    • JUN 08, 2021 | 9:00 AM
      Innovations in Vaccine Research and Development
      Innovations in Vaccine Research and Development
      Date: June 8, 2021 Time: 9:00am PDT Reducing the spread of highly infectious and deadly diseases within the population, vaccine development is crucial in saving millions of lives each year....
      Speaker: Laura Chapman , Ketil Pedersen, Ph.D , Alexander "Sasha" Vlassov , Matt Mckenna
      Sponsored By: Thermo Fisher Scientific
      28 4
      MAY 19, 2021 | 6:00 AM
      Novel Solution For High Throughput Antibody And Protein Purification Using Magnetic Beads
      Novel Solution For High Throughput Antibody And Protein Purification...
      With the ever-increasing demand for antibody and protein-based therapeutics, a flexible purification platform that can handle low to high sample volumes and expression levels is critical for...
      Speaker: Nishant Saxena, PhD
      Presented at: Laboratory Automation Virtual Event Series 2021
      Sponsored By: GenScript
      2
      APR 01, 2021 | 8:00 AM
      Develop High Quality Therapeutic Antibodies Straight From Selections in Record Time
      Develop High Quality Therapeutic Antibodies Straight From Selections...
      Date: April 01, 2021 Time: 8:00am (PST), 11:00am (EST) Generating therapeutic antibodies is far more challenging than obtaining antibodies that merely recognize their targets. Engineering po...
      Speaker: Andrew Bradbury, MD, PhD , Noah Ditto
      Sponsored By: Carterra
      3 1
      MAR 31, 2021 | 8:00 AM
      CytoFLEX SRT Cell Sorter: What is it really like for a user?
      CytoFLEX SRT Cell Sorter: What is it really like for a user?
      Date: March 31, 2021 Time: 08:00am PST CytoFLEX SRT has enabled researcher lead self-service sorting. The need for a cell sorting expert to setup and maintain the sorter status is now necess...
      Speaker: Peter O'Toole, PhD , Dr. Karen Hogg
      Sponsored By: Beckman Coulter Life Sciences
      7
      FEB 24, 2021 | 4:30 PM
      Novel Solutions for High Throughput Antibody and Protein Purification Using Magnetic Beads Platform
      Novel Solutions for High Throughput Antibody and Protein Purification...
      High throughput purification is a critical step for antibody engineering and screening. Protein purification using traditional protein A resin columns is limited by throughput and a complica...
      Speaker: Nishant Saxena, PhD
      Presented at: Drug Discovery & Development Virtual Event Series 2021
      Sponsored By: GenScript
      2
      FEB 24, 2021 | 10:00 AM
      Biosafety Enclosures and the Automated Lab: Steps for Success
      Biosafety Enclosures and the Automated Lab: Steps for Success
      DATE: February 24, 2021 TIME: 10am PST Automated lab instruments such as liquid handlers and cell sorters are increasingly common in all types of laboratories, driving fast results for labor...
      Speaker: David Wasescha , Simon Fogarty
      Sponsored By: Labconco
      15
      FEB 10, 2021 | 7:00 AM
      Influenza vaccine viral protein profiling for viral potency
      Influenza vaccine viral protein profiling for viral potency
      Date: February 10, 2021 Time: 7:00am (PST), 10:00 am (EST) In this talk today we will discuss a new approach to profile influenza proteins. Influenza vaccines typically consist of either a...
      Speaker: Stephen Lock, PhD , Patrick Buckley, PhD
      Sponsored By: SCIEX
      17
      JAN 14, 2021 | 7:00 AM
      Cell Culture Bioprocess Scale-Up Workflow from Bench to Pilot/Production Scale using Single-Use Bioreactors
      Cell Culture Bioprocess Scale-Up Workflow from Bench to Pilot/Production...
      DATE: January 14, 2021 TIME: 7:00am PST Transferring a biologic candidate from the research and development phase to commercial production usually requires increasing the working volume...
      Speaker: Amanda Suttle , Dr. Ma Sha , Rich Mirro
      Presented at: Eppendorf Planet of Knowledge - A New Dimension
      Sponsored By: Eppendorf
      16 1
      DEC 10, 2020 | 8:00 AM
      Simple and Fast Charge Variants Analysis of mAbs by CZE
      Simple and Fast Charge Variants Analysis of mAbs by CZE
      Date: December 10, 2020 Time: 8:00am (PST), 11:00am (EST) As you face increasingly shortened timelines to bring new drugs to market, you find yourself strained to finalize analytical methods...
      Speaker: Yan He, Ph.D.
      Sponsored By: SCIEX
      4 1
      DEC 02, 2020 | 8:00 AM
      Optimize your bioprocess - From shaker to bioreactor
      Optimize your bioprocess - From shaker to bioreactor
      DATE: December 2nd, 2020 TIME: 08:00am PDT, 11:00pm EDT Bioreactors and shakers are used to cultivate microorganisms, plant, insect, and mammalian cells in different volumes. Upscaling of pr...
      Speaker: Ines Hartmann , David Solbach
      Sponsored By: Eppendorf
      11
      NOV 19, 2020 | 8:00 AM
      From discovery to functional assays: therapeutic antibody research by Miltenyi Biotec
      From discovery to functional assays: therapeutic antibody research...
      Date: November 19, 2020 Time: 8:00am PST, 11:00am EST Monoclonal antibody-based drugs have shown great potential as a treatment for several cancers. At Miltenyi Biotec, we offer a complete wo...
      Speaker: Dr. Susanne Bethke
      Sponsored By: Miltenyi Biotec
      9
      NOV 12, 2020 | 10:00 AM
      FcRn Affinity Column Chromatography for Therapeutic mAb Characterization
      FcRn Affinity Column Chromatography for Therapeutic mAb Characterization
      Date: November 12, 2020 Time: 10:00am (PST), 1:00pm (EST) Fc receptor based affinity chromatography is a new emerging field of Fc functionality analytics. FcRn affinity columns separate anti...
      Speaker: Tilman Schlothauer, Ph.D
      Sponsored By: Roche CustomBiotech
      3
      OCT 21, 2020 | 12:00 AM
      Developing a Complete Workflow Including N-Linked Glycans Analysis for Monoclonal Antibodies with High Resolution Mass Spectrometry and Fluorescence Detection
      Developing a Complete Workflow Including N-Linked Glycans Analysis...
      Accurate characterization of monoclonal antibodies is essential to development of biotherapeutics. Thorough understanding of biotherapeutic properties aids in the optimization of bioprocess...
      Speaker: Brian Domanski
      Presented at: Analytical Chemistry & Separation Sciences Virtual Event Series 2020
      1
      OCT 08, 2020 | 12:00 PM
      ZooMAb® Antibodies- a Novel Recombinant Antibody Technology
      ZooMAb® Antibodies- a Novel Recombinant Antibody Technology
      Antibodies have become one of the most important tools in life science research, allowing the detection, quantitation, and determination of changes in proteins and other molecules with respe...
      Speaker: Wayne Speckmann, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
      Sponsored By: MilliporeSigma
      2
      OCT 07, 2020 | 12:00 PM
      Drugging the Undruggable Cancer Targets
      Drugging the Undruggable Cancer Targets
      Cancer is a multifactorial disease, and its genesis and progression are extremely complex. The scope of precision oncology is rapidly expanding to address previously undruggable targets. The...
      Speaker: Dr. Ming Liu
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
      Sponsored By: ChemPartner
      1
      SEP 22, 2020 | 10:00 AM
      Characterization of N-linked glycans with the Released Glycans Workflow of MassHunter Bioconfirm Software
      Characterization of N-linked glycans with the Released Glycans...
      Monoclonal antibodies are heterogeneous molecules that include glycosylation variants, carboxyl truncation, and deamidation that require extensive analytical characterization. These molecule...
      Speaker: Rebecca Glaskin
      Presented at: Agilent Biopharma Workflow Solutions Virtual Symposium: Advances in Glycan and Sialic Acid Analysis
      1
      SEP 15, 2020 | 8:00 AM
      Next generation ultra high content analysis of the tumor immune microenvironment using MICS technology
      Next generation ultra high content analysis of the tumor immune...
      DATE: September 15, 2020 TIME: 08:00am PT Tumorigenesis and cancer progression are affected by the tumor immune microenvironment (TIME). The TIME not only influences the efficiency of existi...
      Speaker: Stefan Eulitz
      Sponsored By: Miltenyi Biotec
      15 2
      SEP 10, 2020 | 9:00 AM
      An Insider's Look: How One Parameter Can Optimize Key Phases of Bioprocessing Workflows
      An Insider's Look: How One Parameter Can Optimize Key Phases of...
      Date: September 10, 2020 Time: 9:00am (PDT), 12:00pm (EDT) Osmolality testing is relevant throughout the entire bioprocessing workflow. As customers look to refine mAb and gene therapy workf...
      Speaker: Tara Barreira , Kristeena Wright
      Sponsored By: Advanced Instruments
      7
      SEP 08, 2020 | 12:00 PM
      Keynote Presentation: Structure-based Vaccine Design for COVID-19 and other Respiratory Viruses
      Keynote Presentation: Structure-based Vaccine Design for COVID-19...
      While the frequency of pandemic threats seems to be increasing, we fortunately have new tools and technologies to make vaccines with more precision and speed and that support a more proactiv...
      Speaker: Barney S. Graham, MD, PhD
      Presented at: Microbiology Week Virtual Event Series 2020
      1
      SEP 03, 2020 | 9:00 AM
      The Complexities of SV Analytical Ultracentrifugation: AAVs are not Simple, Binary Systems
      The Complexities of SV Analytical Ultracentrifugation: AAVs are...
      DATE: September 3, 2020 TIME: 09:00am PT, 12:00pm ET xxx Learning Objectives: xxx Webinars will be available for unlimited on-demand viewing after live event. LabRoots is approved as a provi...
      Speaker: Dr. Lake Paul
      Sponsored By: Beckman Coulter Life Sciences
      12
      AUG 25, 2020 | 8:00 AM
      How LV and AAV Transfection Platforms will Shape the Future of Gene Therapy Manufacturing
      How LV and AAV Transfection Platforms will Shape the Future of...
      DATE: August 25, 2020 TIME: 8:00am PDT, 10:00am CDT, 11:00am EDT Recombinant lentivirus (LV) and adeno-associated virus (AAV) are critical components of cell and gene therapies, which show g...
      Speaker: Leisha Kopp
      Sponsored By: Mirus
      18 2
      AUG 11, 2020 | 10:00 AM
      Better resolution for CE-SDS analysis of new biopharmaceutical modalities through fine-tuning the separation temperature
      Better resolution for CE-SDS analysis of new biopharmaceutical...
      DATE: August 11, 2020 TIME: 10:00am PDT, 1:00pm EDT Biopharma researchers facing a difficult time adopting CE-SDS for purity/heterogeneity analysis of new protein modalities can now...
      Speaker: Andras Guttman, PhD
      Sponsored By: SCIEX
      9 4
      AUG 06, 2020 | 10:00 AM
      Single Cell Antibody Discovery Using 'Islands of Automation'
      Single Cell Antibody Discovery Using 'Islands of Automation'
      DATE: August 6th, 2020 TIME: 10:00am PT In recent years Lilly has implemented a Next Generation Research (NGR) initiative to improve the value output of the R&D portfolio. One of the NGR...
      Speaker: Paul Anderson
      Sponsored By: Beckman Coulter Life Sciences
      16 5
      JUN 30, 2020 | 9:00 AM
      Quality Control for the Pharmaceutical Industry; Stage 3, Continued Verification, in the Lifecycle of Analytical Procedures
      Quality Control for the Pharmaceutical Industry; Stage 3, Continued...
      DATE: June 30, 2020 TIME: 9:00am PDT, 12:00pm EDT QC laboratories perform a critical role in demonstrating pharmaceutical products are consistently manufactured, safe, potent, and pure. At t...
      Speaker: Jane Weitzel
      Sponsored By: Sartorius
      17 1
    JUN 08, 2021 | 9:00 AM
    Innovations in Vaccine Research and Development
    Innovations in Vaccine Research and Development
    Date: June 8, 2021 Time: 9:00am PDT Reducing the spread of highly infectious and deadly diseases within the population, vaccine development is crucial in saving millions of lives each year....
    Speaker: Laura Chapman , Ketil Pedersen, Ph.D , Alexander "Sasha" Vlassov , Matt Mckenna
    Sponsored By: Thermo Fisher Scientific
    28 4
    MAY 19, 2021 | 6:00 AM
    Novel Solution For High Throughput Antibody And Protein Purification Using Magnetic Beads
    Novel Solution For High Throughput Antibody And Protein Purification...
    With the ever-increasing demand for antibody and protein-based therapeutics, a flexible purification platform that can handle low to high sample volumes and expression levels is critical for...
    Speaker: Nishant Saxena, PhD
    Presented at: Laboratory Automation Virtual Event Series 2021
    Sponsored By: GenScript
    2
    APR 01, 2021 | 8:00 AM
    Develop High Quality Therapeutic Antibodies Straight From Selections in Record Time
    Develop High Quality Therapeutic Antibodies Straight From Selections...
    Date: April 01, 2021 Time: 8:00am (PST), 11:00am (EST) Generating therapeutic antibodies is far more challenging than obtaining antibodies that merely recognize their targets. Engineering po...
    Speaker: Andrew Bradbury, MD, PhD , Noah Ditto
    Sponsored By: Carterra
    3 1
    MAR 31, 2021 | 8:00 AM
    CytoFLEX SRT Cell Sorter: What is it really like for a user?
    CytoFLEX SRT Cell Sorter: What is it really like for a user?
    Date: March 31, 2021 Time: 08:00am PST CytoFLEX SRT has enabled researcher lead self-service sorting. The need for a cell sorting expert to setup and maintain the sorter status is now necess...
    Speaker: Peter O'Toole, PhD , Dr. Karen Hogg
    Sponsored By: Beckman Coulter Life Sciences
    7
    FEB 24, 2021 | 4:30 PM
    Novel Solutions for High Throughput Antibody and Protein Purification Using Magnetic Beads Platform
    Novel Solutions for High Throughput Antibody and Protein Purification...
    High throughput purification is a critical step for antibody engineering and screening. Protein purification using traditional protein A resin columns is limited by throughput and a complica...
    Speaker: Nishant Saxena, PhD
    Presented at: Drug Discovery & Development Virtual Event Series 2021
    Sponsored By: GenScript
    2
     
     
  • FEB 24, 2021 | 10:00 AM
    Biosafety Enclosures and the Automated Lab: Steps for Success
    Biosafety Enclosures and the Automated Lab: Steps for Success
    DATE: February 24, 2021 TIME: 10am PST Automated lab instruments such as liquid handlers and cell sorters are increasingly common in all types of laboratories, driving fast results for labor...
    Speaker: David Wasescha , Simon Fogarty
    Sponsored By: Labconco
    15
    FEB 10, 2021 | 7:00 AM
    Influenza vaccine viral protein profiling for viral potency
    Influenza vaccine viral protein profiling for viral potency
    Date: February 10, 2021 Time: 7:00am (PST), 10:00 am (EST) In this talk today we will discuss a new approach to profile influenza proteins. Influenza vaccines typically consist of either a...
    Speaker: Stephen Lock, PhD , Patrick Buckley, PhD
    Sponsored By: SCIEX
    17
    JAN 14, 2021 | 7:00 AM
    Cell Culture Bioprocess Scale-Up Workflow from Bench to Pilot/Production Scale using Single-Use Bioreactors
    Cell Culture Bioprocess Scale-Up Workflow from Bench to Pilot/Production...
    DATE: January 14, 2021 TIME: 7:00am PST Transferring a biologic candidate from the research and development phase to commercial production usually requires increasing the working volume...
    Speaker: Amanda Suttle , Dr. Ma Sha , Rich Mirro
    Presented at: Eppendorf Planet of Knowledge - A New Dimension
    Sponsored By: Eppendorf
    16 1
    DEC 10, 2020 | 8:00 AM
    Simple and Fast Charge Variants Analysis of mAbs by CZE
    Simple and Fast Charge Variants Analysis of mAbs by CZE
    Date: December 10, 2020 Time: 8:00am (PST), 11:00am (EST) As you face increasingly shortened timelines to bring new drugs to market, you find yourself strained to finalize analytical methods...
    Speaker: Yan He, Ph.D.
    Sponsored By: SCIEX
    4 1
    DEC 02, 2020 | 8:00 AM
    Optimize your bioprocess - From shaker to bioreactor
    Optimize your bioprocess - From shaker to bioreactor
    DATE: December 2nd, 2020 TIME: 08:00am PDT, 11:00pm EDT Bioreactors and shakers are used to cultivate microorganisms, plant, insect, and mammalian cells in different volumes. Upscaling of pr...
    Speaker: Ines Hartmann , David Solbach
    Sponsored By: Eppendorf
    11
     
     
  • NOV 19, 2020 | 8:00 AM
    From discovery to functional assays: therapeutic antibody research by Miltenyi Biotec
    From discovery to functional assays: therapeutic antibody research...
    Date: November 19, 2020 Time: 8:00am PST, 11:00am EST Monoclonal antibody-based drugs have shown great potential as a treatment for several cancers. At Miltenyi Biotec, we offer a complete wo...
    Speaker: Dr. Susanne Bethke
    Sponsored By: Miltenyi Biotec
    9
    NOV 12, 2020 | 10:00 AM
    FcRn Affinity Column Chromatography for Therapeutic mAb Characterization
    FcRn Affinity Column Chromatography for Therapeutic mAb Characterization
    Date: November 12, 2020 Time: 10:00am (PST), 1:00pm (EST) Fc receptor based affinity chromatography is a new emerging field of Fc functionality analytics. FcRn affinity columns separate anti...
    Speaker: Tilman Schlothauer, Ph.D
    Sponsored By: Roche CustomBiotech
    3
    OCT 21, 2020 | 12:00 AM
    Developing a Complete Workflow Including N-Linked Glycans Analysis for Monoclonal Antibodies with High Resolution Mass Spectrometry and Fluorescence Detection
    Developing a Complete Workflow Including N-Linked Glycans Analysis...
    Accurate characterization of monoclonal antibodies is essential to development of biotherapeutics. Thorough understanding of biotherapeutic properties aids in the optimization of bioprocess...
    Speaker: Brian Domanski
    Presented at: Analytical Chemistry & Separation Sciences Virtual Event Series 2020
    1
    OCT 08, 2020 | 12:00 PM
    ZooMAb® Antibodies- a Novel Recombinant Antibody Technology
    ZooMAb® Antibodies- a Novel Recombinant Antibody Technology
    Antibodies have become one of the most important tools in life science research, allowing the detection, quantitation, and determination of changes in proteins and other molecules with respe...
    Speaker: Wayne Speckmann, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
    Sponsored By: MilliporeSigma
    2
    OCT 07, 2020 | 12:00 PM
    Drugging the Undruggable Cancer Targets
    Drugging the Undruggable Cancer Targets
    Cancer is a multifactorial disease, and its genesis and progression are extremely complex. The scope of precision oncology is rapidly expanding to address previously undruggable targets. The...
    Speaker: Dr. Ming Liu
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2020
    Sponsored By: ChemPartner
    1
     
     
  • SEP 22, 2020 | 10:00 AM
    Characterization of N-linked glycans with the Released Glycans Workflow of MassHunter Bioconfirm Software
    Characterization of N-linked glycans with the Released Glycans...
    Monoclonal antibodies are heterogeneous molecules that include glycosylation variants, carboxyl truncation, and deamidation that require extensive analytical characterization. These molecule...
    Speaker: Rebecca Glaskin
    Presented at: Agilent Biopharma Workflow Solutions Virtual Symposium: Advances in Glycan and Sialic Acid Analysis
    1
    SEP 15, 2020 | 8:00 AM
    Next generation ultra high content analysis of the tumor immune microenvironment using MICS technology
    Next generation ultra high content analysis of the tumor immune...
    DATE: September 15, 2020 TIME: 08:00am PT Tumorigenesis and cancer progression are affected by the tumor immune microenvironment (TIME). The TIME not only influences the efficiency of existi...
    Speaker: Stefan Eulitz
    Sponsored By: Miltenyi Biotec
    15 2
    SEP 10, 2020 | 9:00 AM
    An Insider's Look: How One Parameter Can Optimize Key Phases of Bioprocessing Workflows
    An Insider's Look: How One Parameter Can Optimize Key Phases of...
    Date: September 10, 2020 Time: 9:00am (PDT), 12:00pm (EDT) Osmolality testing is relevant throughout the entire bioprocessing workflow. As customers look to refine mAb and gene therapy workf...
    Speaker: Tara Barreira , Kristeena Wright
    Sponsored By: Advanced Instruments
    7
    SEP 08, 2020 | 12:00 PM
    Keynote Presentation: Structure-based Vaccine Design for COVID-19 and other Respiratory Viruses
    Keynote Presentation: Structure-based Vaccine Design for COVID-19...
    While the frequency of pandemic threats seems to be increasing, we fortunately have new tools and technologies to make vaccines with more precision and speed and that support a more proactiv...
    Speaker: Barney S. Graham, MD, PhD
    Presented at: Microbiology Week Virtual Event Series 2020
    1
    SEP 03, 2020 | 9:00 AM
    The Complexities of SV Analytical Ultracentrifugation: AAVs are not Simple, Binary Systems
    The Complexities of SV Analytical Ultracentrifugation: AAVs are...
    DATE: September 3, 2020 TIME: 09:00am PT, 12:00pm ET xxx Learning Objectives: xxx Webinars will be available for unlimited on-demand viewing after live event. LabRoots is approved as a provi...
    Speaker: Dr. Lake Paul
    Sponsored By: Beckman Coulter Life Sciences
    12
     
     
  • AUG 25, 2020 | 8:00 AM
    How LV and AAV Transfection Platforms will Shape the Future of Gene Therapy Manufacturing
    How LV and AAV Transfection Platforms will Shape the Future of...
    DATE: August 25, 2020 TIME: 8:00am PDT, 10:00am CDT, 11:00am EDT Recombinant lentivirus (LV) and adeno-associated virus (AAV) are critical components of cell and gene therapies, which show g...
    Speaker: Leisha Kopp
    Sponsored By: Mirus
    18 2
    AUG 11, 2020 | 10:00 AM
    Better resolution for CE-SDS analysis of new biopharmaceutical modalities through fine-tuning the separation temperature
    Better resolution for CE-SDS analysis of new biopharmaceutical...
    DATE: August 11, 2020 TIME: 10:00am PDT, 1:00pm EDT Biopharma researchers facing a difficult time adopting CE-SDS for purity/heterogeneity analysis of new protein modalities can now...
    Speaker: Andras Guttman, PhD
    Sponsored By: SCIEX
    9 4
    AUG 06, 2020 | 10:00 AM
    Single Cell Antibody Discovery Using 'Islands of Automation'
    Single Cell Antibody Discovery Using 'Islands of Automation'
    DATE: August 6th, 2020 TIME: 10:00am PT In recent years Lilly has implemented a Next Generation Research (NGR) initiative to improve the value output of the R&D portfolio. One of the NGR...
    Speaker: Paul Anderson
    Sponsored By: Beckman Coulter Life Sciences
    16 5
    JUN 30, 2020 | 9:00 AM
    Quality Control for the Pharmaceutical Industry; Stage 3, Continued Verification, in the Lifecycle of Analytical Procedures
    Quality Control for the Pharmaceutical Industry; Stage 3, Continued...
    DATE: June 30, 2020 TIME: 9:00am PDT, 12:00pm EDT QC laboratories perform a critical role in demonstrating pharmaceutical products are consistently manufactured, safe, potent, and pure. At t...
    Speaker: Jane Weitzel
    Sponsored By: Sartorius
    17 1
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