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    Regulation of translation

    Translation is the biological process during which information encoded in mRNA is relayed resulting in a string of amino acids that make up a protein. Regulation of translation ensures the level of protein synthesized from mRNA is adequate to maintain homeostasis within the cell. Translational regulation both the type of protein and amount of protein synthesized from mRNA.

    Webinars

    • MAR 17, 2016 | 9:00 AM
      Featured Speaker - The neurobiology underlying drug addiction: lessons from multimodality imaging and neuropsychological studies in humans
      Featured Speaker - The neurobiology underlying drug addiction:...
      Drug addiction is a chronically relapsing disorder characterized by compulsive drug use despite catastrophic personal consequences (e.g., loss of family, job) and even when the substance is n...
      Speaker: Rita Goldstein, PhD
      Presented at: Neuroscience Virtual Event Series 2016
      2
      MAR 16, 2016 | 12:00 PM
      Featured Speaker - Striatal Synaptic Dysfunction in Parkinson's disease
      Featured Speaker - Striatal Synaptic Dysfunction in Parkinson's...
      Traditional models of basal ganglia disorders are grounded in the assumption that network dysfunction is driven by alterations in intrinsic excitability of striatal neurons. Recent work has c...
      Speaker: D James Surmeier, PhD
      Presented at: Neuroscience Virtual Event Series 2016
      0
      FEB 24, 2016 | 1:00 PM
      From genomics to precision medicine: Uncovering and manipulating the genetic circuits underlying common disease
      From genomics to precision medicine: Uncovering and manipulating...
      Precision medicine requires understanding the mechanistic basis of complex disorders, and to precisely manipulate these mechanisms to better human health. This is partly enabled by the recent...
      Speaker: Manolis Kellis, PhD
      Presented at: Precision Medicine Virtual Event Series 2016
      2
      FEB 24, 2016 | 7:00 AM
      Precision Medicine Approaches and the Future of Drug Development in Oncology
      Precision Medicine Approaches and the Future of Drug Development...
      A number of recently publications have heralded the advent of Precision Medicine in Oncology, where next generation sequencing technology, other ’omics technologies, serial biopsies, so...
      Speaker: Thomas Metcalfe
      Presented at: Precision Medicine Virtual Event Series 2016
      3
      JAN 15, 2016 | 4:00 AM
      Multiplex IHC and novel monoclonal antibodies as enabling tools for the study of tumor immunology
      Multiplex IHC and novel monoclonal antibodies as enabling tools...
      DATE: January 15, 2016 TIME: 7am EST, 12pm UK, 1pm CET With an increasing number of biomarkers and, often, limited availability of biopsy material, there is a growing need for multiplexed...
      Speaker: Matthew Silver, PhD
      Sponsored By: Cell Signaling Technology, Cell Signaling Technology
      10 1
      NOV 11, 2015 | 6:00 AM
      A Comprehensive Toxicology Screening Solution Targeted to Individual Needs
      A Comprehensive Toxicology Screening Solution Targeted to Individual...
      Drugs of abuse toxicology testing by immunoassays is widely used clinically, but also known to be inadequate for many clinical indications. In this presentation, the speaker will outline diff...
      Speaker: Ping Wang, PhD, DABCC, FACB
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2015
      3
      SEP 03, 2015 | 3:00 PM
      Next-Generation Sequencing for Diagnosis and Surveillance of Emerging Infections
      Next-Generation Sequencing for Diagnosis and Surveillance of Emerging...
      Next-generation sequencing (NGS) technologies are powerful approaches for diagnosis and surveillance of emerging infections. Unbiased metagenomic NGS can detect the full spectrum of pathogen...
      Speaker: Charles Chiu, MD, PhD
      Presented at: Microbiology Virtual Event Series 2015
      2
      SEP 02, 2015 | 12:00 PM
      Polyamines in bacterial growth and biofilm formation
      Polyamines in bacterial growth and biofilm formation
      Polyamines are small, mostly linear organic molecules found in almost all living cells, and are positively charged at physiological pH. As a consequence of their positive charge, polyamines b...
      Speaker: Anthony Michael, PhD
      Presented at: Microbiology Virtual Event Series 2015
      3
      SEP 02, 2015 | 6:00 AM
      Structure and Function of the Human Microbiome
      Structure and Function of the Human Microbiome
      Among many surprising insights, the genomic revolution has helped us to realize that we're never alone and, in fact, barely human. For most of our lives, we share our bodies with some ten ti...
      Speaker: Curtis Huttenhower, PhD
      Presented at: Microbiology Virtual Event Series 2015
      9
      MAY 14, 2015 | 12:00 PM
      Regulation of mRNA translation by ribosomes
      Regulation of mRNA translation by ribosomes
      Over the past few years, evidence has been accumulating to indicate that ribosomal subunits are not simply tape-heads that decode mRNA sequences into polypeptide chains, but that they also pl...
      Speaker: Vincent P Mauro, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2015
      3
      MAR 18, 2015 | 10:30 AM
      Special Lecturer - Oxidative Stress in Schizophrenia: a Translational Approach
      Special Lecturer - Oxidative Stress in Schizophrenia: a Translational...
      Schizophrenia is a severe psychiatric disorder affecting 1% of the world’s population, leading to high human, social and economic burdens. Understanding how the interaction of gene and...
      Speaker: Kim Quang Do, PhD
      Presented at: Neuroscience Virtual Event Series 2015
      12
      MAR 18, 2015 | 6:00 AM
      Keynote -Dopamine System Dysregulation in the Pathophysiology of Schizophrenia and Depression
      Keynote -Dopamine System Dysregulation in the Pathophysiology...
      The dopamine-containing neurons of the midbrain have been implicated in a broad array of psychiatric disorders, ranging from schizophrenia to drug abuse and depression. However, studies seem...
      Speaker: Anthony Grace, PhD
      Presented at: Neuroscience Virtual Event Series 2015
      11
      OCT 30, 2014 | 1:30 PM
      Structural Pathways of Cancer
      Structural Pathways of Cancer
      Structural pathways are important. They are essential to the understanding of how oncogenic mutations work and to figuring out alternative parallel pathways in drug resistant mutants. Structu...
      Speaker: Ruth Nussinov, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      16
      OCT 29, 2014 | 3:00 PM
      Molecular Prognosis in the Management of Early Stage Lung Cancer
      Molecular Prognosis in the Management of Early Stage Lung Cancer
      Survival rates for early stage non-small cell lung cancer (NSCLC) remain unacceptably low compared to other common solid tumors. This mortality reflects a weakness in conventional staging, as...
      Speaker: Michael J Mann, MD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      67
      OCT 29, 2014 | 9:00 AM
      Reading and disrupting the histone code with chemical agents: making new tools to understand epigenetic methylation pathways in stem-like cancers
      Reading and disrupting the histone code with chemical agents:...
      Post-translational methylations play central roles in epigenetic gene regulation pathways that are central to stem cell regulation. Lysine methylations are turn-on switches for hundreds of di...
      Speaker: Fraser Hof, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      7
      OCT 29, 2014 | 6:00 AM
      Expanding the scope of RNA-Seq to archival FFPE samples
      Expanding the scope of RNA-Seq to archival FFPE samples
      As next-generation sequencing (NGS) platforms advance in their speed, ease-of-use, and cost-effectiveness, many translational researchers are transitioning from microarrays to RNA sequencing...
      Speaker: Kelli Bramlett, M.S.
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
      4
      SEP 24, 2014 | 3:00 PM
      Site-directed ligand discovery for cryptic sites and other challenging targets
      Site-directed ligand discovery for cryptic sites and other challenging...
      Protein-protein interactions and allosterically regulated enzymes have been challenging but important targets for probe- and drug discovery. We and others have found that fragment-based lead...
      Speaker: Michelle Arkin, PhD
      Presented at: Advances in Drug Discovery and Development
      20
      SEP 10, 2014 | 10:00 AM
      NGS Lessons in Translational Diagnostics
      NGS Lessons in Translational Diagnostics
      In this webinar, we will describe a comprehensive approach for NGS-based marker discovery and the successful migration of these markers to targeted NGS assays using low-quality (FFPE) and low...
      Speaker: Gary Latham Ph.D. and Brian Haynes, Ph.D.
      Sponsored By: Asuragen, Asuragen
      48
      AUG 21, 2014 | 12:45 PM
      Predictive and not: understanding the mixed messages of our DNA
      Predictive and not: understanding the mixed messages of our DNA
      When whole genome and whole exome sequencing are introduced into health care, and offered directly to consumers in commercial settings, the landscape of genetic testing will drastically chang...
      Speaker: Cecile Janssens, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2014
      36
      AUG 20, 2014 | 11:45 AM
      Ethical, Legal and Social Issues of Direct-to-Consumer Genetic Testing
      Ethical, Legal and Social Issues of Direct-to-Consumer Genetic...
      Direct-to-consumer (DTC) genetic testing can be understood as including two related aspects: first, the advertising of genetic tests directly to consumers; and second, the direct access or or...
      Speaker: Heidi C Howard, PhD
      Presented at: Genetics and Genomics Virtual Event Series 2014
      25
      MAY 30, 2014 | 7:30 AM
      Multiplexed Fusion Gene Detection using Next Generation Sequencing
      Multiplexed Fusion Gene Detection using Next Generation Sequencing
      As next-generation sequencing (NGS) platforms advance in their speed, ease-of-use, and cost-effectiveness, many translational researchers are transitioning from microarrays to RNA sequencing...
      Speaker: Kelli Bramlett and Jeoffrey Schageman
      Presented at: Clinical Diagnostics & Research Virtual Event Series 2014
      82
      MAR 19, 2014 | 11:00 AM
      When good neurons go bad: Dopamine neuron regulation and its disruption in schizophrenia and depression
      When good neurons go bad: Dopamine neuron regulation and its disruption...
      ...
      Speaker: Anthony Grace, PhD
      Presented at: Neuroscience Virtual Event Series 2014
      36
      OCT 23, 2013 | 12:00 PM
      Cellular regulation of the molecular chaperone HSP90 by posttranslational modifications - impact on function and drug sensitivity
      Cellular regulation of the molecular chaperone HSP90 by posttranslational...
      Molecular chaperones help nascent polypeptides fold correctly and multimeric protein complexes assemble productively, while minimizing the danger of aggregation in the protein-rich intracellu...
      Speaker: Len Neckers, PhD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      2
      OCT 16, 2013 | 11:00 AM
      Molecular Prognosis in the Management of Early Stage Lung Cancer
      Molecular Prognosis in the Management of Early Stage Lung Cancer
      Survival rates for early stage non-small cell lung cancer (NSCLC) remain unacceptably low compared to other common solid tumors. This mortality reflects a weakness in conventional staging, a...
      Speaker: Michael J Mann, MD
      Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
      58
    MAR 17, 2016 | 9:00 AM
    Featured Speaker - The neurobiology underlying drug addiction: lessons from multimodality imaging and neuropsychological studies in humans
    Featured Speaker - The neurobiology underlying drug addiction:...
    Drug addiction is a chronically relapsing disorder characterized by compulsive drug use despite catastrophic personal consequences (e.g., loss of family, job) and even when the substance is n...
    Speaker: Rita Goldstein, PhD
    Presented at: Neuroscience Virtual Event Series 2016
    2
    MAR 16, 2016 | 12:00 PM
    Featured Speaker - Striatal Synaptic Dysfunction in Parkinson's disease
    Featured Speaker - Striatal Synaptic Dysfunction in Parkinson's...
    Traditional models of basal ganglia disorders are grounded in the assumption that network dysfunction is driven by alterations in intrinsic excitability of striatal neurons. Recent work has c...
    Speaker: D James Surmeier, PhD
    Presented at: Neuroscience Virtual Event Series 2016
    0
    FEB 24, 2016 | 1:00 PM
    From genomics to precision medicine: Uncovering and manipulating the genetic circuits underlying common disease
    From genomics to precision medicine: Uncovering and manipulating...
    Precision medicine requires understanding the mechanistic basis of complex disorders, and to precisely manipulate these mechanisms to better human health. This is partly enabled by the recent...
    Speaker: Manolis Kellis, PhD
    Presented at: Precision Medicine Virtual Event Series 2016
    2
    FEB 24, 2016 | 7:00 AM
    Precision Medicine Approaches and the Future of Drug Development in Oncology
    Precision Medicine Approaches and the Future of Drug Development...
    A number of recently publications have heralded the advent of Precision Medicine in Oncology, where next generation sequencing technology, other ’omics technologies, serial biopsies, so...
    Speaker: Thomas Metcalfe
    Presented at: Precision Medicine Virtual Event Series 2016
    3
    JAN 15, 2016 | 4:00 AM
    Multiplex IHC and novel monoclonal antibodies as enabling tools for the study of tumor immunology
    Multiplex IHC and novel monoclonal antibodies as enabling tools...
    DATE: January 15, 2016 TIME: 7am EST, 12pm UK, 1pm CET With an increasing number of biomarkers and, often, limited availability of biopsy material, there is a growing need for multiplexed...
    Speaker: Matthew Silver, PhD
    Sponsored By: Cell Signaling Technology, Cell Signaling Technology
    10 1
     
     
  • NOV 11, 2015 | 6:00 AM
    A Comprehensive Toxicology Screening Solution Targeted to Individual Needs
    A Comprehensive Toxicology Screening Solution Targeted to Individual...
    Drugs of abuse toxicology testing by immunoassays is widely used clinically, but also known to be inadequate for many clinical indications. In this presentation, the speaker will outline diff...
    Speaker: Ping Wang, PhD, DABCC, FACB
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2015
    3
    SEP 03, 2015 | 3:00 PM
    Next-Generation Sequencing for Diagnosis and Surveillance of Emerging Infections
    Next-Generation Sequencing for Diagnosis and Surveillance of Emerging...
    Next-generation sequencing (NGS) technologies are powerful approaches for diagnosis and surveillance of emerging infections. Unbiased metagenomic NGS can detect the full spectrum of pathogen...
    Speaker: Charles Chiu, MD, PhD
    Presented at: Microbiology Virtual Event Series 2015
    2
    SEP 02, 2015 | 12:00 PM
    Polyamines in bacterial growth and biofilm formation
    Polyamines in bacterial growth and biofilm formation
    Polyamines are small, mostly linear organic molecules found in almost all living cells, and are positively charged at physiological pH. As a consequence of their positive charge, polyamines b...
    Speaker: Anthony Michael, PhD
    Presented at: Microbiology Virtual Event Series 2015
    3
    SEP 02, 2015 | 6:00 AM
    Structure and Function of the Human Microbiome
    Structure and Function of the Human Microbiome
    Among many surprising insights, the genomic revolution has helped us to realize that we're never alone and, in fact, barely human. For most of our lives, we share our bodies with some ten ti...
    Speaker: Curtis Huttenhower, PhD
    Presented at: Microbiology Virtual Event Series 2015
    9
    MAY 14, 2015 | 12:00 PM
    Regulation of mRNA translation by ribosomes
    Regulation of mRNA translation by ribosomes
    Over the past few years, evidence has been accumulating to indicate that ribosomal subunits are not simply tape-heads that decode mRNA sequences into polypeptide chains, but that they also pl...
    Speaker: Vincent P Mauro, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2015
    3
     
     
  • MAR 18, 2015 | 10:30 AM
    Special Lecturer - Oxidative Stress in Schizophrenia: a Translational Approach
    Special Lecturer - Oxidative Stress in Schizophrenia: a Translational...
    Schizophrenia is a severe psychiatric disorder affecting 1% of the world’s population, leading to high human, social and economic burdens. Understanding how the interaction of gene and...
    Speaker: Kim Quang Do, PhD
    Presented at: Neuroscience Virtual Event Series 2015
    12
    MAR 18, 2015 | 6:00 AM
    Keynote -Dopamine System Dysregulation in the Pathophysiology of Schizophrenia and Depression
    Keynote -Dopamine System Dysregulation in the Pathophysiology...
    The dopamine-containing neurons of the midbrain have been implicated in a broad array of psychiatric disorders, ranging from schizophrenia to drug abuse and depression. However, studies seem...
    Speaker: Anthony Grace, PhD
    Presented at: Neuroscience Virtual Event Series 2015
    11
    OCT 30, 2014 | 1:30 PM
    Structural Pathways of Cancer
    Structural Pathways of Cancer
    Structural pathways are important. They are essential to the understanding of how oncogenic mutations work and to figuring out alternative parallel pathways in drug resistant mutants. Structu...
    Speaker: Ruth Nussinov, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    16
    OCT 29, 2014 | 3:00 PM
    Molecular Prognosis in the Management of Early Stage Lung Cancer
    Molecular Prognosis in the Management of Early Stage Lung Cancer
    Survival rates for early stage non-small cell lung cancer (NSCLC) remain unacceptably low compared to other common solid tumors. This mortality reflects a weakness in conventional staging, as...
    Speaker: Michael J Mann, MD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    67
    OCT 29, 2014 | 9:00 AM
    Reading and disrupting the histone code with chemical agents: making new tools to understand epigenetic methylation pathways in stem-like cancers
    Reading and disrupting the histone code with chemical agents:...
    Post-translational methylations play central roles in epigenetic gene regulation pathways that are central to stem cell regulation. Lysine methylations are turn-on switches for hundreds of di...
    Speaker: Fraser Hof, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    7
     
     
  • OCT 29, 2014 | 6:00 AM
    Expanding the scope of RNA-Seq to archival FFPE samples
    Expanding the scope of RNA-Seq to archival FFPE samples
    As next-generation sequencing (NGS) platforms advance in their speed, ease-of-use, and cost-effectiveness, many translational researchers are transitioning from microarrays to RNA sequencing...
    Speaker: Kelli Bramlett, M.S.
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2014
    4
    SEP 24, 2014 | 3:00 PM
    Site-directed ligand discovery for cryptic sites and other challenging targets
    Site-directed ligand discovery for cryptic sites and other challenging...
    Protein-protein interactions and allosterically regulated enzymes have been challenging but important targets for probe- and drug discovery. We and others have found that fragment-based lead...
    Speaker: Michelle Arkin, PhD
    Presented at: Advances in Drug Discovery and Development
    20
    SEP 10, 2014 | 10:00 AM
    NGS Lessons in Translational Diagnostics
    NGS Lessons in Translational Diagnostics
    In this webinar, we will describe a comprehensive approach for NGS-based marker discovery and the successful migration of these markers to targeted NGS assays using low-quality (FFPE) and low...
    Speaker: Gary Latham Ph.D. and Brian Haynes, Ph.D.
    Sponsored By: Asuragen, Asuragen
    48
    AUG 21, 2014 | 12:45 PM
    Predictive and not: understanding the mixed messages of our DNA
    Predictive and not: understanding the mixed messages of our DNA
    When whole genome and whole exome sequencing are introduced into health care, and offered directly to consumers in commercial settings, the landscape of genetic testing will drastically chang...
    Speaker: Cecile Janssens, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2014
    36
    AUG 20, 2014 | 11:45 AM
    Ethical, Legal and Social Issues of Direct-to-Consumer Genetic Testing
    Ethical, Legal and Social Issues of Direct-to-Consumer Genetic...
    Direct-to-consumer (DTC) genetic testing can be understood as including two related aspects: first, the advertising of genetic tests directly to consumers; and second, the direct access or or...
    Speaker: Heidi C Howard, PhD
    Presented at: Genetics and Genomics Virtual Event Series 2014
    25
     
     
  • MAY 30, 2014 | 7:30 AM
    Multiplexed Fusion Gene Detection using Next Generation Sequencing
    Multiplexed Fusion Gene Detection using Next Generation Sequencing
    As next-generation sequencing (NGS) platforms advance in their speed, ease-of-use, and cost-effectiveness, many translational researchers are transitioning from microarrays to RNA sequencing...
    Speaker: Kelli Bramlett and Jeoffrey Schageman
    Presented at: Clinical Diagnostics & Research Virtual Event Series 2014
    82
    MAR 19, 2014 | 11:00 AM
    When good neurons go bad: Dopamine neuron regulation and its disruption in schizophrenia and depression
    When good neurons go bad: Dopamine neuron regulation and its disruption...
    ...
    Speaker: Anthony Grace, PhD
    Presented at: Neuroscience Virtual Event Series 2014
    36
    OCT 23, 2013 | 12:00 PM
    Cellular regulation of the molecular chaperone HSP90 by posttranslational modifications - impact on function and drug sensitivity
    Cellular regulation of the molecular chaperone HSP90 by posttranslational...
    Molecular chaperones help nascent polypeptides fold correctly and multimeric protein complexes assemble productively, while minimizing the danger of aggregation in the protein-rich intracellu...
    Speaker: Len Neckers, PhD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    2
    OCT 16, 2013 | 11:00 AM
    Molecular Prognosis in the Management of Early Stage Lung Cancer
    Molecular Prognosis in the Management of Early Stage Lung Cancer
    Survival rates for early stage non-small cell lung cancer (NSCLC) remain unacceptably low compared to other common solid tumors. This mortality reflects a weakness in conventional staging, a...
    Speaker: Michael J Mann, MD
    Presented at: Cancer: Research, Discovery and Therapeutics Virtual Event Series 2013
    58
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