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Approximately 30% of drugs have failed in human clinical trials due to adverse reactions despite promising pre-clinical studies, and another 60% fail due to lack of efficacy. The NIH Tissue C...
The adeno-associated virus (AAV) has evolved overlapping genes to maximize its genome use, as with the recently-discovered ORF in the cap gene which encodes a membrane-associated accessory p...
The CSIRO Tissue Culture Facility (CTCF) employs a range of in-house optimized platform technologies to identify optimum vector-host cell combinations for both transient and stable protein pr...
COVID-19 remains a global health emergency with limited treatment options, lagging vaccine rates, and inadequate healthcare resources in the face of an ongoing calamity. The disease is chara...
DATE: February 8, 2017TIME: 12:00pm PT, 3:00pm ETLarge animal models have recently become a staple in biomedical research. The pig’s similarities to humans in terms of genet...
There are an urgent need for antivirals to treat the newly emerged SARS-CoV-2. We set out to develop cell-based screens to repurpose existing drugs for use against SARS-CoV-2. Our goal was t...
Regulatory agencies across the world are responsible for enforcing regulations for different industries. Industries must adhere to these regulations to assure the quality of their products a...
Cell free DNA (cfDNA) analysis for the purpose of diagnostics is currently practiced for non-invasive prenatal screening of cell free fetal DNA (cffDNA), and is anticipated to be leveraged fo...
The inability of neurons to regenerate damaged axons within the CNS has dire consequences for victims of traumatic or ischemic brain injury and multiple neurodegenerative diseases. Like other...
Pancreatic β cell replacement therapy is considered as a potential strategy to treat diabetes. To date, transplantation of pancreatic islets from cadavers is the most effective approach...
The most recently developed genome editing system, CRISPR-Cas9 has greater inherent flexibility than prior programmable nuclease platforms. Because of its simplicity and efficacy, this techno...
The All of Us Research Program is a historic effort to gather data from one million or more people living in the United States to accelerate research and improve health. By taking into accoun...
Multi-Drug Resistant Organisms (MDROs) are becoming a bigger and bigger concern throughout the world. Antibiotic resistance forms and spreads faster than pharmaceutical companies have been ab...
This presentation will focus on the near- and medium-term future of COVID. COVID will become endemic, but what does this really mean? How will COVID affect longevity in the United States? Wh...
The spread of the SARS-COV-2 (COVID-19) pandemic is driving an urgent need for extensive testing, including patients and health workers as a priority. The most sensitive and reliable method...
To execute COVID-19 testing strategies effectively, labs need to procure reliable components of the workflow without interruption – from reagents to equipment and consumables at the sc...
Learning objectives:1. Metagenomic analysis is already complex, and complicated further by incomplete and non-standardized databases of known organisms2. Fungi may have their own 'mic...
Facioscapulohumeral muscular dystrophy (FSHD), one of the most common forms of progressive muscular dystrophies and is often conventionally diagnosed by Southern blot analysis. The accurate d...
Embark on an enlightening journey through the intricate landscape of loop-mediated isothermal amplification (LAMP) technology. Unveil the ingenious mechanism of rapid DNA amplification under...
Clinical laboratories worldwide are implementing various targeted panels to identify cancer genomic variants and ultimately improve patient outcomes. As most of the panels and NGS platforms...
Automating Cannabis Testing with Laboratory Information Management Systems (LIMS) Software systems automate not only key aspects of laboratory testing, but provide a comprehensive data manage...
Detection of neural signatures related to pathological behavioral states could enable adaptive deep brain stimulation (DBS), a potential strategy for improving efficacy of DBS for neurologic...
Kinetic antibody internalization assays using live-cell analysisMonoclonal antibodies (mAb) and antibody-drug conjugates (ADCs) are widely used biological therapeutics. A key property of...
Vitamin D3 supplementation can effectively remedy the current epidemic of vitamin D deficiency, especially within the African-American population and the elderly of any ethnicity. Racial disp...
Approximately 30% of drugs have failed in human clinical trials due to adverse reactions despite promising pre-clinical studies, and another 60% fail due to lack of efficacy. The NIH Tissue C...
