Advances in cell and molecular biology have catapulted our understanding of the science of life from the basic understanding of how cells and the components of cells interact within living organisms. Remain up to date on recent discoveries and revelations through these webinars.
The disposition of antibody-based therapeutics is generally determined by both target-mediated and non-target processes, the latter being an often-overlooked aspect. Target-independent liabi...
Cell and gene therapy is at the forefront of medical innovation, offering transformative potential for treating complex diseases. However, achieving success in these therapies requires metic...
I will present my lab’s effort on studying and manipulating RNA processing, with particular emphasis on using CRISPR/Cas systems for targeting RNA in living cells in diseases such as my...
Thinking about a starting a job search? Join us to listen to some tips to help you prepare for starting a successful career/job search. Topics covered: Resume Writing tips, Preparing fo...
The exponential advents of advances in techniques and types of molecular diagnostic testing, and modifying strategies for these tests, are encouraging; but these evolutions simultaneously con...
The path from research discovery to effective immune cell therapies requires innovative approaches to match the challenges we face. Examining the full richness of biological complexity&mdash...
After a brief definition of terms (what are bioplastics?), this lecture will discuss various material and application examples for biobased and/or biodegradable plastics. An overview on the...
On measuring photons and ions: Impact on panel design, signal detection and data quality 10:30–11:00 am PDT Presented By: Tim Bushnell, PhD, MBA Monitoring immunotherapy with a mass cy...
The capture of tumor-derived extracellular vesicles (TEVs) by cells in the tumor microenvironment (TME) contributes to metastasis and notably to the formation of the pre-metastatic niche (PM...
From gene cloning and initial clone selection through to final cell evaluation, the continual assessment of cell count and viability is important for determining the best growing and highest...
Extracellular ligands bind to receptors on the cell surface leading to receptor internalization. Once internalized into small vesicles, the vesicles fuse with an organelle known as the sorti...
Tumor phenotypes are dictated not only by the neoplastic cell component, but also by the tumor microenvironment (TME), which is inherently immuno-suppressive, is equipped to hamper effector...
Extracellular vesicles (EVs) are lipid bilayer-delimited pieces of cells that are released from the plasma membrane as "ectosomes" and from the endosomal system as "exosomes.&...
Checkpoint blockade therapy for cancer has had tremendous impact on clinical outcomes, yet only a subset of patients respond. Recent studies show that response to checkpoint blockade does not...
Biomedical researchers are increasingly using advanced human cell models for translational biology and therapeutic discovery studies. These include patient-specific samples, cultured micro-ti...
Date: September 16, 2021 Time: 8:00am (PDT), 11:00am (EDT) Rapid screening and speed of scale-up in protein therapeutics are critical factors in today’s biotech and pharma workflows. T...
Inborn errors of metabolism (IEMs) are rare, devastating disorders caused by pathogenic variants in genes encoding key metabolic enzymes, with the liver playing a critical role in over 140 I...
Multi-target screening can offer great insight into the genetic pathways in drug resistance and disease. RNAi and the fast pace of CRISPR technology development has brought sophisticated opt...
Current methods used to predict safety and efficacy of candidate drugs accounts for as much as 90% failure rate. Approximately 30% of drugs have failed......
The global incidence of cancer is on a steady rise, with a projected annual diagnosis rate of nearly 30 million cases by 2040. Despite this alarming trend, our understanding of the intricate...
Super-resolution microscopy, or nanoscopy, enables the use of fluorescent-based molecular localization tools to study molecular structure at the nanoscale level in the intact cell. Analysis...
Extracellular vesicles (EV) from many cell types have demonstrated therapeutic potential against many different diseases. Inhibiting progress in this area is the capability to produce EVs in...
The microcapillary-based technology behind the Guava® range of flow cytometers and analyzers offers compact, waste-reducing solutions for all cell health verification and counting needs....
Bladder cancer is the 4th most prevalent cancer in men, 11th in women and presents one of the highest rates of post-treatment recurrence (70%) among malignancies. Despite its impact on human...
Cells of the liver and pancreas are highly polarized and well differentiated, contributing to food digestion through the secretion of lipid emulsifying bile, and proteolytic juice into the g...
Healthy human red blood cells (RBCs) gradually degrade over their lifespan of ~120 days. However, sickle cells - RBCs from sickle cell disease (SCD) patients - degrade much faster within the...
Macrophages have been implicated in both the resolution and progression of influenza, but the drivers of these outcomes are poorly understood. We probed mouse lung transcriptomic datasets us...
The disposition of antibody-based therapeutics is generally determined by both target-mediated and non-target processes, the latter being an often-overlooked aspect. Target-independent liabi...
