Follow a curation of discoveries and updates in immunology focusing on immune responses to infectious disease, structure and function, and developments in the defense against infection by watching and engaging in these webinars.
When producing a quality vaccine, all manufacturers must confirm the purity as well as the stability of their formulation and final product. Sample quantity and measurement time are often th...
Background Protection from SARS-CoV-2 vaccines wanes over time and is compounded by emerging variants including Omicron subvariants. This study evaluated safety and immunogenicity of SARS-Co...
1. Identify 3 barriers to immune cell response to cancer 2. List 3 approaches to overcome immunosuppressive barriers to bolster the immune response to cancer 3. Explain how fusion proteins c...
A key step in the clinical production of CAR T cells is the expansion of engineered T cells. To generate enough cells for viable adoptive cell therapy, cells must be robustly stimulated, whi...
Learning Objectives: 1. Discuss the value of infectious disease diagnostics. 2. Recognize the importance of home diagnostics. 3. Identify how better diagnostics leads to more resiliency to p...
Cases and deaths continue to increase steadily in most states. The pace of increase is faster than we expected, leading us to revise upward IHME forecast of deaths and cases into the future....
The risk of mortality from COVID-19 follows a sharp age gradient, with older populations facing a thousand fold higher risk of death upon infection than children. At the same time, the COVID...
NCI estimates that cancer will be the leading cause of death in 2030, worldwide. Checkpoint inhibitors and adoptive cell therapies (ACTs) cost up to ~$2 million/patient and have shown durabl...
During the first year of the SARS-CoV-2 pandemic, international monitoring of SARS-CoV-2 genomic RNA revealed that the virus accumulated roughly 2 mutations per month. Nonetheless, one nonsy...
Viruses and virally transmitted diseases have been impacting human health and well-being for hundreds of years. Some of our greatest scientific challenges and medical triumphs have involved...
One significant challenge with SARS-CoV-2 wastewater monitoring is the lack of optimized and standardized sample processing steps, from sample collection to RNA detection. Viral concentratio...
Learning Objectives: 1. Drug Repurposing Strategies for SARS-CoV2 2. Validation pipeline for SARS-CoV-2 antiviral 3. Outlook for SARS-CoV-2 therapeutics...
SARS-CoV-2 vaccine efficacy testing is now facing increasing challenges in the face of an ongoing pandemic with the emergence of new variants and waning vaccine immunity. Evidence supports t...
SARS-CoV-2 spreads through airborne transmission. Aerosols containing live virus are dispersed when an infected person exhales and then continue to accumulate indoors, putting others at risk...
Vaccination and infection are two different paths to immunity. Understanding human immune responses to SARS-CoV-2 RNA vaccines is of interest for a panoply of reasons. mRNA vaccines have dem...
CAR-T translational research demands precise, reproducible, and scalable flow cytometry workflows. Manual centrifugation and antibody preparation steps remain major sources of variability an...
Join me, an applied epidemiologist with boots on the ground, as we review key discoveries learned from the reopening of sports, entertainment and the arts. The four pillars of reopening incl...
Dr. Koenitzer will present an overview of her current research in immune suppression. After a brief introduction to the MILLIPLEX® multiplex immunoassay portfolio, Dr. Koenitzer will dis...
Multiplex immunofluorescence IHC is a powerful technique to address the increasing research needs in immuno-oncology to better understand the tumor microenvironment. In this webinar, we will...
In all organisms, innate immune pathways sense infection and rapidly activate potent immune responses while maintaining a high degree of specificity to prevent inappropriate activation (auto...
Flaviviruses are pathogens of global public health concern. They include dengue virus (DENV), West Nile virus (WNV), and zika virus (ZIKV). There are no approved US Food and Drug Administrat...
Metastatic prostate cancer (mPC) is a phenotypically diverse disease with poor responses to immune based therapeutics. Development of immunotherapeutic strategies for mPC is hampered by the...
While providing indispensable insight into immune processes, the live cell imaging of immune cells poses unique challenges due to their non-adherent nature. Suspension cells such as immune c...
The forecast IHME released on March 26, 2020, was geared to helping hospitals plan for a surge in demand for their resources (e.g., beds, ICUs, ventilators) to fight COVID-19. With many loca...
We use COVID-19 cases, hospitalizations, and mortality data and a deterministic SEIR (susceptible, exposed, infectious and recovered) compartmental framework to model possible trajectories o...
Multiplexed immunofluorescent imaging sheds new light on cancer and other complex conditions. This imaging technique offers a deeper understanding of cells and their surroundings by providin...
The ongoing COVID-19 pandemic has increased awareness about sex-specific differences in immunity and outcomes following respiratory virus infections. Strong evidence of a male bias in acute...