An RNA virus is a type of virus that has RNA as genetic material. As the RNA virus enters the host, the virus makes use of the presence of endogenous cellular RNA-dependent RNA polymerases. This allows the virus to replicate its genome and integrate itself into the host's DNA. Once integrated, the virus may become latent (such as in HIV infection) or maybe be transcribed to continually produce new viral proteins (such as in SARS-CoV-2 infection). Examples of RNA viruses include the hepatitis C virus, the virus that causes Ebola, SARS-CoV-2 (the virus that causes the COVID-19 disease), polio, measles, and the HIV virus.
DATE: June 30, 2020 TIME: 10:00 am PDT, 1:00 pm EDT COVID-19 is a highly pathogenic disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We have assembled a panel...
In his 2018 TED talk “How to build synthetic DNA and send it across the internet,” Dr. Dan Gibson highlighted a unique synthetic biology approach for fighting pandemics such as S...
Understanding the complex interplay between a pathogen and the host response is important to developing effective vaccines and therapeutics. The nCounter® Analysis System and GeoMx®...
The spread of the SARS-COV-2 (COVID-19) pandemic is driving an urgent need for extensive testing, including patients and health workers as a priority. The most sensitive and reliable method...
Next-generation sequencing (NGS) is the primary technology used to identify genomic targets for vaccine development, detect emerging viral strains and monitor transmission patterns. Enhanced...
DATE: June 11, 2020 TIME: 10:00am PT, 1:00pm ET Correlative light and electron microscopy (CLEM) enables biological discoveries by merging different microscopes and imaging modalities to stu...
Background and aim: Rapid and complex diagnosis of viral, bacterial and parasitic infections is highly desirable not only in clinical practice, but also in food safety or early warning syste...
BGI group has been at the forefront in the fight against covid-19. Starting from building a lab in Wuhan, sequencing first 2019-nCoV virus genome and offering RT-PCR and sequencing based det...
Learning Objectives: 1. What kind of virus is the coronavirus? Where is its greatest vulnerability and why? 2. What differentiated the HCoVs discovered in the 1960s from the SARS-CoV and MER...
DATE: December 11, 2019 TIME: 7:00am PST, 10:00am EST Rapid growth in the cell and gene therapy industry has generated an urgent need for robust analytics around characterization of both vec...
Despite FDA-approved vaccines and antivirals, seasonal and pandemic influenza remains a serious threat associated with substantial morbidity and mortality. The present modalities and vaccine...
Respiratory viral infections remain a leading cause of medical visits and can contribute significantly to morbidity and mortality. Influenza, together with pneumonia, is the leading infectiou...
Since the establishment of reverse genetics techniques to manipulate the influenza virus genome, it has been possible to study viral molecular signatures responsible for virulence, and the ge...
immunocompromised populations where the virus can cause systemic and even fatal infections. Indeed, we have shown that astrovirus infections are more prevalent than norovirus in our pediatric...
DATE: September 5, 2019TIME: 7:00am PT, 10:00am ET, 4:00pm CEST PCR (Polymerase Chain Reaction) has gone through a massive evolution since its development in 1983. Besides it...
DATE: May 15, 2019TIME: 9:00am PDTHepatitis B infections remain a significant global healthcare burden resulting in 887,000 deaths in 2015. Clinical laboratories can have a measurable i...
“Emerging infections” are those that appear suddenly or are rapidly increasing in incidence or geographic range (e.g., HIV/AIDS, Ebola, SARS, Middle East Respiratory Syndrome [MER...
The Ebola virus disease outbreak in West Africa in 2014-2016 was the largest of its kind in history. This was the first outbreak that involved a randomized clinical trial for therapeutics, a...
Rapid, inexpensive, and sensitive nucleic acid detection may aid point-of-care pathogen detection, genotyping, and disease monitoring. We combine the RNA- targeting CRISPR effector Cas13 with...
DATE: November 15,2018TIME: 06:00am PST, 09:00am EST, 3:00pm CET Hepatitis D virus (HDV) is a unique RNA virus that requires the hepatitis B surface antigen (HBsAg) to...
Machine learning approaches to pattern discovery in protein-protein interaction networks of Huntington’s disease brain and model organisms are revealing novel connections of the disease...
Plant viruses cause significant damage in terms of reduction in quality and quantity of yield in a wide range of crop plants worldwide. The majority of plant viruses are transmitted from one...
Genome sequencing can be used to discover new pathogens but it can also be used to monitor known ones. This is known as genomic surveillance and it becoming an increasingly important tool in...
DATE: June 30, 2020 TIME: 10:00 am PDT, 1:00 pm EDT COVID-19 is a highly pathogenic disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We have assembled a panel...
In his 2018 TED talk “How to build synthetic DNA and send it across the internet,” Dr. Dan Gibson highlighted a unique synthetic biology approach for fighting pandemics such as S...
Understanding the complex interplay between a pathogen and the host response is important to developing effective vaccines and therapeutics. The nCounter® Analysis System and GeoMx®...
The spread of the SARS-COV-2 (COVID-19) pandemic is driving an urgent need for extensive testing, including patients and health workers as a priority. The most sensitive and reliable method...
Next-generation sequencing (NGS) is the primary technology used to identify genomic targets for vaccine development, detect emerging viral strains and monitor transmission patterns. Enhanced...
DATE: June 11, 2020 TIME: 10:00am PT, 1:00pm ET Correlative light and electron microscopy (CLEM) enables biological discoveries by merging different microscopes and imaging modalities to stu...
Background and aim: Rapid and complex diagnosis of viral, bacterial and parasitic infections is highly desirable not only in clinical practice, but also in food safety or early warning syste...
BGI group has been at the forefront in the fight against covid-19. Starting from building a lab in Wuhan, sequencing first 2019-nCoV virus genome and offering RT-PCR and sequencing based det...
Learning Objectives: 1. What kind of virus is the coronavirus? Where is its greatest vulnerability and why? 2. What differentiated the HCoVs discovered in the 1960s from the SARS-CoV and MER...
DATE: December 11, 2019 TIME: 7:00am PST, 10:00am EST Rapid growth in the cell and gene therapy industry has generated an urgent need for robust analytics around characterization of both vec...
Despite FDA-approved vaccines and antivirals, seasonal and pandemic influenza remains a serious threat associated with substantial morbidity and mortality. The present modalities and vaccine...
Respiratory viral infections remain a leading cause of medical visits and can contribute significantly to morbidity and mortality. Influenza, together with pneumonia, is the leading infectiou...
Since the establishment of reverse genetics techniques to manipulate the influenza virus genome, it has been possible to study viral molecular signatures responsible for virulence, and the ge...
immunocompromised populations where the virus can cause systemic and even fatal infections. Indeed, we have shown that astrovirus infections are more prevalent than norovirus in our pediatric...
DATE: September 5, 2019TIME: 7:00am PT, 10:00am ET, 4:00pm CEST PCR (Polymerase Chain Reaction) has gone through a massive evolution since its development in 1983. Besides it...
DATE: May 15, 2019TIME: 9:00am PDTHepatitis B infections remain a significant global healthcare burden resulting in 887,000 deaths in 2015. Clinical laboratories can have a measurable i...
“Emerging infections” are those that appear suddenly or are rapidly increasing in incidence or geographic range (e.g., HIV/AIDS, Ebola, SARS, Middle East Respiratory Syndrome [MER...
The Ebola virus disease outbreak in West Africa in 2014-2016 was the largest of its kind in history. This was the first outbreak that involved a randomized clinical trial for therapeutics, a...
Rapid, inexpensive, and sensitive nucleic acid detection may aid point-of-care pathogen detection, genotyping, and disease monitoring. We combine the RNA- targeting CRISPR effector Cas13 with...
DATE: November 15,2018TIME: 06:00am PST, 09:00am EST, 3:00pm CET Hepatitis D virus (HDV) is a unique RNA virus that requires the hepatitis B surface antigen (HBsAg) to...
Machine learning approaches to pattern discovery in protein-protein interaction networks of Huntington’s disease brain and model organisms are revealing novel connections of the disease...
Plant viruses cause significant damage in terms of reduction in quality and quantity of yield in a wide range of crop plants worldwide. The majority of plant viruses are transmitted from one...
Genome sequencing can be used to discover new pathogens but it can also be used to monitor known ones. This is known as genomic surveillance and it becoming an increasingly important tool in...
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