Cells carry out specialized functions throughout the body and each cell type functions distinctly from other cell types. Some cellular functions include transporting nutrients throughout the body and producing energy. One specialized cell is muscle cells which function to create a force that moves parts of the body. Another example are bone cells, whose functions include protecting internal organs from damage and storing minerals such as calcium.
The world–as microbes perceive it–is composed of physical and chemical stimuli. These stimuli create conditions that result in life or death for microbes, affecting their survival...
Polyamines are small, mostly linear organic molecules found in almost all living cells, and are positively charged at physiological pH. As a consequence of their positive charge, polyamines b...
Advances in sequencing technology and increasing recognition of the importance of our microbial world have led to unprecedented discoveries in recent years with respect to the human microbiom...
The human race, like all macrobiological life, evolved in a sea of microbes. There was no way to keep the bacterial and archaeal hoards at bay, so instead life evolved mechanisms to live with...
Human microbiome projects have delivered our first glimpse into the microbial communities that reside in and on our bodies. Building on these efforts the research community has begun to corre...
Among many surprising insights, the genomic revolution has helped us to realize that we're never alone and, in fact, barely human. For most of our lives, we share our bodies with some ten ti...
DATE: July 22, 2015TIME: 9:00AM PT, 12:00PM ETHuman induced pluripotent stem cells (iPSCs) bring human biology into pre-clinical aspects of drug discovery. iPSC-derived cardiomyocytes have em...
DATE: June 17th, 2015TIME: 8am Pacific time, 11am Eastern timeSpatial heterogeneity of tumors has been identified within and between metastatic lesions and can be visualized wit...
Date: June 16, 2015Time: 8:00AM Pacific time, 11:00AM Eastern TimeGroup 2 innate lymphoid cells (ILC2s) are recently described innate immune cells that contribute to type 2 inflammation, tiss...
I will discuss the use of genomic technologies - mostly ultrahigh-throughput DNA sequencing - to study normal human biology and to determine what goes wrong when we have disease. First I wil...
Genome Wide Association Studies (GWAS) and eQTL analyses are producing huge numbers of associations and show no signs of slowing. There are now more than 8,500 SNPs associated with more than...
Long noncoding RNAs (lncRNAs) are increasingly recognized as having key regulatory roles in development and disease. However, these regulatory molecules often have short half lives and are ex...
The Allen Institute for Brain Science provides several brain atlases that are freely available to the public at www.brain-map.org. A common use for these atlases is to study expression patter...
Every major scientific and technological revolution in history has been driven by one thing: access to data. Today, the availability of Big Data from a wide variety of sources is transforming...
Please click here to watch this webinar On DemandsiRNA-mediated silencing of gene expression has revolutionized the study of biology by enabling rapid and unbiased loss-of-function studies to...
Extracellular vesicles (EVs) include the exosomes (30-100 nm) that are produced through the endocytic pathway via the multivesicular bodies and the ectosomes (100-1000 nm) that are released t...
Date: Tuesday, April 7th, 2015Time: 8:30AM PST, 11:30AM EST, 5:30PM CETThe development of new medicines for Diabetes Type 2 complications has proven to be challenging due to the use of cell...
DARPA’s investments aim to leverage brain-function research to alleviate the burden of illness and injury and provide novel, neurotechnology-based capabilities for military personnel an...
The NIH BRAIN initiative, informed by the report from the scientific community (BRAIN 2025) is underway. The major funded efforts at this time fit into 3 main categories; 1) defining the comp...
There is growing interest internationally in elucidating the clinical and biological profile of those at high genetic risk to bipolar disorder (BD) so as to enable the development of targeted...
Impulsivity can be defined as the tendency to act prematurely without foresight. Behavioural and neurobiological analysis of this construct, based on evidence from both animal and human studi...
Recent advances in noninvasive neuroimaging have set the stage for the systematic exploration of human brain circuits in health and disease. The Human Connectome Project (HCP) is systematical...
At the cellular and molecular levels of operation, neurons and their circuits achieve brain functions by chemical signals, in which the principle agents, neurotransmitters convey the signal f...
The hippocampal formation is one of the most extensively studied regions of the brain, with well described anatomy and basic physiology; moreover, aspects of human memory mediated by hippocam...
The world–as microbes perceive it–is composed of physical and chemical stimuli. These stimuli create conditions that result in life or death for microbes, affecting their survival...
Polyamines are small, mostly linear organic molecules found in almost all living cells, and are positively charged at physiological pH. As a consequence of their positive charge, polyamines b...
Advances in sequencing technology and increasing recognition of the importance of our microbial world have led to unprecedented discoveries in recent years with respect to the human microbiom...
The human race, like all macrobiological life, evolved in a sea of microbes. There was no way to keep the bacterial and archaeal hoards at bay, so instead life evolved mechanisms to live with...
Human microbiome projects have delivered our first glimpse into the microbial communities that reside in and on our bodies. Building on these efforts the research community has begun to corre...
Among many surprising insights, the genomic revolution has helped us to realize that we're never alone and, in fact, barely human. For most of our lives, we share our bodies with some ten ti...
DATE: July 22, 2015TIME: 9:00AM PT, 12:00PM ETHuman induced pluripotent stem cells (iPSCs) bring human biology into pre-clinical aspects of drug discovery. iPSC-derived cardiomyocytes have em...
DATE: June 17th, 2015TIME: 8am Pacific time, 11am Eastern timeSpatial heterogeneity of tumors has been identified within and between metastatic lesions and can be visualized wit...
Date: June 16, 2015Time: 8:00AM Pacific time, 11:00AM Eastern TimeGroup 2 innate lymphoid cells (ILC2s) are recently described innate immune cells that contribute to type 2 inflammation, tiss...
I will discuss the use of genomic technologies - mostly ultrahigh-throughput DNA sequencing - to study normal human biology and to determine what goes wrong when we have disease. First I wil...
Genome Wide Association Studies (GWAS) and eQTL analyses are producing huge numbers of associations and show no signs of slowing. There are now more than 8,500 SNPs associated with more than...
Long noncoding RNAs (lncRNAs) are increasingly recognized as having key regulatory roles in development and disease. However, these regulatory molecules often have short half lives and are ex...
The Allen Institute for Brain Science provides several brain atlases that are freely available to the public at www.brain-map.org. A common use for these atlases is to study expression patter...
Every major scientific and technological revolution in history has been driven by one thing: access to data. Today, the availability of Big Data from a wide variety of sources is transforming...
Please click here to watch this webinar On DemandsiRNA-mediated silencing of gene expression has revolutionized the study of biology by enabling rapid and unbiased loss-of-function studies to...
Extracellular vesicles (EVs) include the exosomes (30-100 nm) that are produced through the endocytic pathway via the multivesicular bodies and the ectosomes (100-1000 nm) that are released t...
Date: Tuesday, April 7th, 2015Time: 8:30AM PST, 11:30AM EST, 5:30PM CETThe development of new medicines for Diabetes Type 2 complications has proven to be challenging due to the use of cell...
DARPA’s investments aim to leverage brain-function research to alleviate the burden of illness and injury and provide novel, neurotechnology-based capabilities for military personnel an...
The NIH BRAIN initiative, informed by the report from the scientific community (BRAIN 2025) is underway. The major funded efforts at this time fit into 3 main categories; 1) defining the comp...
There is growing interest internationally in elucidating the clinical and biological profile of those at high genetic risk to bipolar disorder (BD) so as to enable the development of targeted...
Impulsivity can be defined as the tendency to act prematurely without foresight. Behavioural and neurobiological analysis of this construct, based on evidence from both animal and human studi...
Recent advances in noninvasive neuroimaging have set the stage for the systematic exploration of human brain circuits in health and disease. The Human Connectome Project (HCP) is systematical...
At the cellular and molecular levels of operation, neurons and their circuits achieve brain functions by chemical signals, in which the principle agents, neurotransmitters convey the signal f...
The hippocampal formation is one of the most extensively studied regions of the brain, with well described anatomy and basic physiology; moreover, aspects of human memory mediated by hippocam...
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